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CKD, glomerulonephritis, renal failure, dialysis,

Luana Rodrigues Sarmento, Paula Frassinetti Castelo Branco Camurça Fernandes, Marcelo Ximenes Pontes, Daniel Barros Santos Correia, Victhor Castelo Branco Chaves, Cecília Ferreira de Araújo Carvalho, Tiago Lima Arnaud, Matheus Henrique Seixas Dos Santos, Livia Cristina Barros Barreto, Larissa Alves Alexandre Moliterno
INTRODUCTION: Knowledge of validated primary causes of end-stage renal disease (ESRD) is extremely relevant in the realm of public health. The literature lacks validated studies on the primary causes of ESRD. OBJECTIVE: The aim of this study was to estimate the prevalence of the causes of ESRD in a State Capital in Northeastern Brazil. METHODS: This cross-sectional study was based on the analysis of medical records of patients on hemodialysis at five specialized centers in Fortaleza, CE, Brazil...
May 17, 2018: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
Marie Patrice Halle, Carine Tsou Lapsap, Esther Barla, Hermine Fouda, Hilaire Djantio, Beatrice Kaptue Moudze, Christophe Adjahoung Akazong, Eugene Belley Priso
BACKGROUND: Pediatric nephrology is challenging in developing countries and data on the burden of kidney disease in children is difficult to estimate due to absence of renal registries. We aimed to describe the epidemiology and outcomes of children with renal failure in Cameroon. METHODS: We retrospectively reviewed 103 medical records of children from 0 to 17 years with renal failure admitted in the Pediatric ward of the Douala General Hospital from 2004 to 2013...
December 6, 2017: BMC Pediatrics
Periyasamy Muthukumar, Jeyachandran Dhanapriya, Natarajan Gopalakrishnan, Thanigachalam Dineshkumar, Ramanathan Sakthirajan, T Balasubramaniyan
The most common causes of renal disease in rheumatoid arthritis (RA) are glomerulonephritis (GN), amyloidosis, tubulo-interstitial nephritis, and drug toxicity. Our aim was to evaluate the clinicopathologic correlation of renal lesions and to assess the course and prognosis of renal disease in patients with RA. We conducted a prospective observational study in all adult patients with RA between July 2010 and June 2015. The total number of patients studied was 90, with a female:male ratio of 2.3:1. Mean follow-up duration was 30 ± 6...
January 2017: Saudi Journal of Kidney Diseases and Transplantation
Vina Tresa, Afshan Yaseen, Ali Asghar Lanewala, Seema Hashmi, Sabeeta Khatri, Irshad Ali, Muhammed Mubarak
BACKGROUND: The reported prevalence rates and etiologies of acute kidney injury (AKI) are quite variable in different regions of the world. The current study was planned to determine the etiology, clinical profile, and short-term outcome of pediatric AKI at our hospital. METHODS: A prospective, observational study was carried out from April 2014 to March 2015. All pediatric patients (1 month to ≤15 years) diagnosed as AKI using modified pRIFLE criteria were studied and followed for 3 months to document short-term outcome...
November 2017: Renal Failure
Jeonghwan Lee, Jung Pyo Lee, Jung Nam An, Sung Gyun Kim, Yong-Lim Kim, Chul Woo Yang, Shin-Wook Kang, Nam-Ho Kim, Yon Su Kim, Yun Kuy Oh, Chun Soo Lim
Timely referral to nephrologists is important for improving clinical outcomes and reducing costs during transition periods. We evaluated the impact of patients' demographic, clinical, and social health characteristics on referral time.A total of 1744 CKD patients who started maintaining dialysis were enrolled in a Korean prospective cohort. The early referral (ER) and late referral group (LR) were defined as patients who were referred to a nephrologist more than or less than 1 year prior to dialysis initiation, respectively...
May 2016: Medicine (Baltimore)
Weihua Li, Shijun Zhang
BACKGROUND: Aberrant mineral metabolism and bone diseases, which are commonly seen in chronic kidney disease (CKD), have been considered to be the important causes of morbidity and decreased quality of life. OBJECTIVES: We aimed to investigate the characteristics of calcium-phosphorus metabolism abnormalities and parathyroid dysfunction in elderly patients with chronic kidney disease undergoing hemodialysis. MATERIAL AND METHODS: A total of 336 patients undergoing maintenance hemodialysis were divided into two age groups: elderly (≥ 65 years) and non-elderly (< 65 years)...
November 2015: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
Gaosi Xu, Wenjun Yan, Jingzhen Li
Nonthyroidal illness syndrome (NTIS) is widely found in the patients with chronic kidney disease (CKD) or critical illness. However, the exact pathogenesis and reasonable treatment remain unclear. To identify suitable studies for inclusion in present review, a search for articles using PubMed search engine with combined terms: (thyroid OR hypothyroidism OR hyperthyroidism OR triiodothyronine) AND (glomerulonephritis OR chronic kidney disease OR chronic renal failure OR end stage renal disease OR hemodialysis OR peritoneal dialysis OR kidney transplantation OR renal transplantation) was performed...
December 2014: Clinical and Experimental Nephrology
David P Ripley, Sri Kannoly, Oliver E Gosling, Ejaz Hossain, Rebecca R Chawner, Jason Moore, Angela C Shore, Nick G Bellenger
AIMS: Current guidelines recommend cardiovascular risk assessment prior to renal transplantation. There is currently no evidence for the role of cardiovascular magnetic resonance (CMR) in this population, despite an established evidence base in the non-chronic kidney disease (CKD) population. Our aim is to determine the feasibility and safety of dobutamine stress CMR (DSCMR) imaging in the risk stratification of CKD patients awaiting renal transplantation. METHODS: CKD patients who were deemed at high risk for coronary artery disease (CAD) and awaiting renal transplantation underwent DSCMR...
April 2014: Journal of Cardiovascular Medicine
E Bili, D Tsolakidis, S Stangou, B Tarlatzis
An increasing number of pregnancies occur in the presence of chronic kidney diseases (CKD), mainly including chronic glomerulonephritis (GN), diabetic nephropathy (DN), and lupus nephritis (LN). The most important factor affecting fetal and maternal prognosis is the degree of renal function at conception. In the majority of patients with mild renal function impairment, and well-controlled blood pressure, pregnancy is usually successful and does not alter the natural course of maternal renal disease. Conversely, fetal outcome and long-term maternal renal function might be seriously threatened by pregnancy in women with moderate or severe renal function impairment...
April 2013: Hippokratia
C O Amira, R W Braimoh, B T Bello
BACKGROUND: The safety of haemodialysis (HD) procedure has improved greatly over the years but, the procedure is not without risks; complications still occur during dialysis. In this study, we report on the pattern of intradialytic complications seen over a one year period at the dialysis centre of the Lagos University Teaching Hospital Lagos (LUTH), Nigeria. METHOD: We reviewed the dialysis and hospital records of consecutive patients with chronic kidney disease (CKD) who received haemodialysis treatment in the dialysis centre during the period between January and December 2010...
December 2012: African Journal of Medicine and Medical Sciences
Keiko Yasuda, Tomonori Kimura, Koichi Sasaki, Yoshitsugu Obi, Kenichiro Iio, Masaya Yamato, Hiromi Rakugi, Yoshitaka Isaka, Terumasa Hayashi
BACKGROUND: As a cardiorenal syndrome, there is a dynamic interplay between the heart and the kidney. We conducted a prospective study to evaluate the prognostic impact of plasma B-type natriuretic peptide (BNP) level, a cardiac biomarker, on the long-term kidney prognosis in chronic kidney disease (CKD) patients. METHODS: We prospectively enrolled 508 patients with CKD Stages 3, 4 and 5 not on dialysis, from a single nephrology department between 2004 and 2010...
October 2012: Nephrology, Dialysis, Transplantation
Iu S Milovanov, L Iu Milovanova
AIM: Comparison of efficacy of 12-month treatment of anemia in patients with chronic kidney disease (CKD) of stage III - IV with a long-acting drug darbepoetin alpha - aranesp and short-acting drug erythropoietin beta - recormon. MATERIAL AND METHODS: A total of 44 patients with CKD of stage III-IVwere divided into two groups. Of them, 24 had chronic glomerulonephritis and 20 had tubulointerstitial nephritis with verified nephrogenic anemia. Group 1 consisted of 22 patients given long-acting erythropoetin (darbepoetin alpha) in an initial dose 0,75 mcg/kg each 2 weeks subcutaneously...
2012: Terapevticheskiĭ Arkhiv
A Chijioke, A M Makusidi, P M Kolo
BACKGROUND: Chronic kidney disease (CKD) has an increased risk of not only end-stage renal disease (ESRD), but majority of moderate CKD patients do die from cardiovascular disease (CVD) before reaching ESRD. The prognosis of these patients is very poor in most developing countries because of late presentation, inadequate diagnostic facilities, and inability to pay for treatment. Knowledge about CVD in CKD is crucial because of unpredictable progressive nature of the disease and increased risk of premature death from cardiovascular events...
January 2012: Annals of African Medicine
Marianna Zsom, Tibor Fülöp, Lajos Zsom, Akos Baráth, Zoltán Maróti, Emoke Endreffy
The relationship between renal disease progression and genetic polymorphism of enzymes influencing endothelial function remains incompletely understood. We genotyped three cohorts of elderly Hungarian patients: 245 patients with end-stage renal disease (ESRD) on chronic hemodialysis (HD), 88 patients with mild chronic kidney disease (CKD), and 200 healthy controls. The underlying diagnoses of renal diseases were primary glomerulonephritis, interstitial nephritis, hypertension, diabetic nephropathy, and hereditary diseases...
October 2011: Hemodialysis International
M O Odubanjo, A O Oluwasola, S Kadiri
The incidence of CKD (Chronic kidney disease) in Nigeria has been shown by various studies to range between 1.6 and 12.4%. We have shown that the burden of renal disease in Nigeria is probably significantly higher than any previous study on end-stage renal disease (ESRD) has documented, as most studies are hospital-based and fail to include the many patients who do not have access to hospital care. The increased prevalence of ESRD among blacks in the United States and South Africa compared with other races also suggests that ESRD may be more prevalent in Africa than in the United States and other developed nations...
September 2011: International Urology and Nephrology
Noriko Takeuchi, Emi Takenoshita, Fumino Kato, Tomoko Terajima, Makoto Ogawa, Satoshi Suzuki, Takayuki Fujii, Eriko Kobayashi, Tomoya Sakurada, Nobunori Satoh, Shiro Ueda
BACKGROUND: The evaluation of the progression of renal insufficiency, or decline in glomerular filtration rate (GFR), has been approached more simply and precisely by converting measured serum creatinine value into the reciprocal of serum creatinine, estimated GFR, or other parameters. Doubling of serum creatinine (simple doubling) is conveniently used as a surrogate endpoint for progression of renal disease but is thought to be biased unfairly by the initial value of serum creatinine (Scr(Int))...
February 2011: Clinical and Experimental Nephrology
Yasuhiko Tomino
Immunoglobulin (Ig)A nephropathy is one of the major causes of chronic kidney disease (CKD) in Japan. Despite statutory urinalysis of industrial workers and school children, Japan unfortunately still ranks among the countries with the highest CKD-5D prevalence in the world. Topics of this review are as follow: (i) early diagnosis and treatment; (ii) influence of the period from onset to medical intervention on renal prognosis; and (iii) epidemiology of IgA nephropathy patients in Japan. Some investigators have discussed the possibility of predicting the diagnosis and prognosis of this disease...
June 2010: Nephrology
Keng-Thye Woo, Kok-Seng Wong, Choong-Meng Chan
The three main causes of Chronic Kidney Diseases [CKD] are diabetes mellitus, chronic glomerulonephritis and hypertension. CKD is an increasing burden in the community as more patients fall prey to kidney failure. Both dialysis and renal transplantation are expensive modalities of treatment for end stage renal failure [ESRF]. Through the years many clinical trials have been performed to retard the progression of CKD to ESRF. Most of the trials focus on three main strategies which aim at renal retardation, namely, control of hypertension, treatment of proteinuria and control of hypercholesterolaemia...
September 2009: Reviews on Recent Clinical Trials
Hasan Nasir Abbas, Malik Anas Rabbani, Nilofer Safdar, Ghulam Murtaza, Qamaruddin Maria, Aasim Ahamd
To determine the nutritional status of chronic hemodialysis (HD) patients and the association of changes in serum albumin levels, C-reactive protein (CRP), low density lipoprotein (LDL) cholesterol and body mass index (BMI) as indicators of nutritional status with the urea reduction ratio (URR) during dialysis, we studied 201 chronic HD patients (97 males and the mean age was 51 +/- 15 years). Diabetes was the cause of chronic kidney disease (CKD) in 34% of the patients, hypertension in 57%, chronic glomerulonephritis in 12%, and obstructive uropathy in 10%...
November 2009: Saudi Journal of Kidney Diseases and Transplantation
Royne Thorman, Martin Neovius, Britta Hylander
OBJECTIVE: Early detection of oral infections plays an important role for dental referral during progression of renal disease and during dialysis treatment in uraemic patients. This study investigated how oral health is related to uraemia in a group of uraemic patients in Stockholm, Sweden. MATERIAL AND METHODS: This cross-sectional study assessed oral diseases in chronic kidney disease (CKD) patients in different stages (n=93) compared with healthy age- and gender-matched controls...
2009: Scandinavian Journal of Urology and Nephrology
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