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https://www.readbyqxmd.com/read/29911968/how-a-nothingoma-can-bring-joy-to-a-physician
#1
Scott Abramson
No abstract text is available yet for this article.
June 11, 2018: Permanente Journal
https://www.readbyqxmd.com/read/29905630/ultrasound-guided-percutaneous-peripheral-nerve-stimulation-neuromodulation-of-the-sciatic-nerve-for-postoperative-analgesia-following-ambulatory-foot-surgery-a-proof-of-concept-study
#2
Brian M Ilfeld, Rodney A Gabriel, Engy T Said, Amanda M Monahan, Jacklynn F Sztain, Wendy B Abramson, Bahareh Khatibi, John J Finneran, Pia T Jaeger, Alexandra K Schwartz, Sonya S Ahmed
BACKGROUND AND OBJECTIVES: Percutaneous peripheral nerve stimulation (PNS) is an analgesic modality involving the insertion of a lead through an introducing needle followed by the delivery of electric current. This modality has been reported to treat chronic pain as well as postoperative pain the day following knee surgery. However, it remains unknown if this analgesic technique may be used in ambulatory subjects following foot procedures beginning within the recovery room immediately following surgery, and with only short series of patients reported to date, the only available data are derived from strictly observational studies...
June 13, 2018: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/29905518/arthur-s-abramson
#3
D H Whalen, Laura L Koenig
No abstract text is available yet for this article.
June 2018: Language and Speech
https://www.readbyqxmd.com/read/29902319/clinicopathological-correlation-of-choroidal-invasion-in-retinoblastoma
#4
David H Abramson, Robert Folberg, Jasmine H Francis
No abstract text is available yet for this article.
June 14, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/29894209/childhood-respiratory-risk-factor-profiles-their-interactions-and-mediators-and-middle-age-lung-function-a-prospective-cohort-study-from-the-1st-to-6th-decade
#5
Dinh S Bui, Haydn E Walters, John A Burgess, Jennifer L Perret, Minh Q Bui, Gayan Bowatte, Adrian J Lowe, Melissa A Russell, Bruce R Thompson, Garun S Hamilton, Alan L James, Graham G Giles, Paul S Thomas, Debbie Jarvis, Cecilie Svanes, Judith Garcia-Aymerich, Bircan Erbas, Peter A Frith, Katrina J Allen, Michael J Abramson, Caroline J Lodge, Shyamali C Dharmage
RATIONALE: Childhood risk factors for long-term lung health often co-exist and their specific patterns may affect subsequent lung function differently. OBJECTIVES: To identify childhood risk factor profiles, their influence on lung function and chronic obstructive pulmonary disease (COPD) in middle-age and potential pathways. METHODS: Profiles of 11 childhood respiratory risk factors, documented at age 7, were identified in 8352 participants from the Tasmanian Longitudinal Health Study using latent class analysis...
June 12, 2018: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/29887666/splenomegaly-segmentation-using-global-convolutional-kernels-and-conditional-generative-adversarial-networks
#6
Yuankai Huo, Zhoubing Xu, Shunxing Bao, Camilo Bermudez, Andrew J Plassard, Jiaqi Liu, Yuang Yao, Albert Assad, Richard G Abramson, Bennett A Landman
Spleen volume estimation using automated image segmentation technique may be used to detect splenomegaly (abnormally enlarged spleen) on Magnetic Resonance Imaging (MRI) scans. In recent years, Deep Convolutional Neural Networks (DCNN) segmentation methods have demonstrated advantages for abdominal organ segmentation. However, variations in both size and shape of the spleen on MRI images may result in large false positive and false negative labeling when deploying DCNN based methods. In this paper, we propose the Splenomegaly Segmentation Network (SSNet) to address spatial variations when segmenting extraordinarily large spleens...
March 2018: Proceedings of SPIE
https://www.readbyqxmd.com/read/29887665/fully-convolutional-neural-networks-improve-abdominal-organ-segmentation
#7
Meg F Bobo, Shunxing Bao, Yuankai Huo, Yuang Yao, Jack Virostko, Andrew J Plassard, Ilwoo Lyu, Albert Assad, Richard G Abramson, Melissa A Hilmes, Bennett A Landman
Abdominal image segmentation is a challenging, yet important clinical problem. Variations in body size, position, and relative organ positions greatly complicate the segmentation process. Historically, multi-atlas methods have achieved leading results across imaging modalities and anatomical targets. However, deep learning is rapidly overtaking classical approaches for image segmentation. Recently, Zhou et al. showed that fully convolutional networks produce excellent results in abdominal organ segmentation of computed tomography (CT) scans...
March 2018: Proceedings of SPIE
https://www.readbyqxmd.com/read/29875233/intravitreal-chemotherapy-in-retinoblastoma-expanded-use-beyond-intravitreal-seeds
#8
David H Abramson, Xunda Ji, Jasmine H Francis, Federica Catalanotti, Scott E Brodie, Larissa Habib
BACKGROUND/AIMS: Ophthalmic artery chemosurgery (OAC) has changed the face of retinoblastoma treatment and led to a higher rate of globe salvage. The introduction of intravitreal chemotherapy (IVitC) has further enhanced globe salvage with increased success in treatment of intravitreal seeds. Our group has seen success at treating non-vitreous disease that is refractory to OAC using IVitC. This study was undertaken to quantify and report on this success. METHODS: A retrospective review was used to identify patients treated with IVitC for indications other than vitreous seeds from two centres...
June 6, 2018: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29870077/diagnosis-of-concomitant-inducible-laryngeal-obstruction-and-asthma
#9
Joy W Lee, Tunn Ren Tay, Paul Paddle, Amanda L Richards, Lisa Pointon, Miriam Voortman, Michael J Abramson, Ryan Hoy, Mark Hew
BACKGROUND: Inducible laryngeal obstruction, an induced, inappropriate narrowing of the larynx, leading to symptomatic upper airway obstruction, can coexist with asthma. Accurate classification has been challenging because of overlapping symptoms and the absence of sensitive diagnostic criteria for either condition. OBJECTIVE: To evaluate patients with concomitant clinical suspicion for inducible laryngeal obstruction and asthma. We used a multidisciplinary protocol incorporating objective diagnostic criteria to determine whether asthma, inducible laryngeal obstruction, both, or neither diagnosis was present...
June 5, 2018: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29851607/effects-of-ambient-pm-1-air-pollution-on-daily-emergency-hospital-visits-in-china-an-epidemiological-study
#10
Gongbo Chen, Shanshan Li, Yongming Zhang, Wenyi Zhang, Daowei Li, Xuemei Wei, Yong He, Michelle L Bell, Gail Williams, Guy B Marks, Bin Jalaludin, Michael J Abramson, Yuming Guo
BACKGROUND: China is experiencing severe ambient air pollution. However, few studies anywhere have examined the health effects of PM1 (particulate matter with aerodynamic diameter <1 μm), which are a major part of PM2·5 (particulate matter with aerodynamic diameter <2·5 μm) and even potentially more harmful than PM2·5 . We aimed to estimate the effects of ambient daily PM1 and PM2·5 concentrations on emergency hospital visits in China. METHODS: In this epidemiological study, we collected daily counts of emergency hospital visits from the 28 largest hospitals in 26 Chinese cities from Sept 9, 2013, to Dec 31, 2014...
September 2017: Lancet. Planetary Health
https://www.readbyqxmd.com/read/29806733/childhood-arthritis-and-rheumatology-research-alliance-consensus-treatment-plans-for-juvenile-idiopathic-arthritis-associated-and-idiopathic-chronic-anterior-uveitis
#11
Sheila T Angeles-Han, Mindy S Lo, Lauren A Henderson, Melissa A Lerman, Leslie Abramson, Ashley M Cooper, Miriam F Parsa, Lawrence S Zemel, Tova Ronis, Timothy Beukelman, Erika Cox, H Nida Sen, Gary N Holland, Hermine I Brunner, Andrew Lasky, C Egla Rabinovich
OBJECTIVE: Systemic immunosuppressive treatment of pediatric chronic anterior uveitis (CAU), both juvenile idiopathic arthritis (JIA)-associated and idiopathic varies, making it difficult to identify best treatments. The Childhood Arthritis and Rheumatology Research Alliance (CARRA) developed consensus treatment plans (CTPs) for CAU for the purpose of reducing practice variability and allowing future comparison of treatments by comparative effectiveness analysis techniques. METHODS: A core group of pediatric rheumatologists, ophthalmologists with uveitis expertise, and a lay advisor comprised the CARRA uveitis workgroup who performed literature review on pharmacologic treatments, held teleconferences, and developed a case-based survey administered to the CARRA membership to delineate treatment practices...
May 28, 2018: Arthritis Care & Research
https://www.readbyqxmd.com/read/29791475/ten-year-experience-with-ophthalmic-artery-chemosurgery-ocular-and-recurrence-free-survival
#12
Jasmine H Francis, Ariana M Levin, Emily C Zabor, Y Pierre Gobin, David H Abramson
PURPOSE: To report associations between disease- and treatment-related variables and rates of recurrence-free survival and ocular survival in eyes treated with ophthalmic artery chemosurgery (OAC) for retinoblastoma. DESIGN: Pre-post study. SUBJECTS: All eyes treated with OAC for retinoblastoma at Memorial Sloan Kettering Cancer Center between May 2006 and February 2017. METHODS: This retrospective review included 452 retinoblastoma eyes treated with OAC...
2018: PloS One
https://www.readbyqxmd.com/read/29788280/genetic-and-environmental-factors-affecting-birth-size-variation-a-pooled-individual-based-analysis-of-secular-trends-and-global-geographical-differences-using-26-twin-cohorts
#13
Yoshie Yokoyama, Aline Jelenkovic, Yoon-Mi Hur, Reijo Sund, Corrado Fagnani, Maria A Stazi, Sonia Brescianini, Fuling Ji, Feng Ning, Zengchang Pang, Ariel Knafo-Noam, David Mankuta, Lior Abramson, Esther Rebato, John L Hopper, Tessa L Cutler, Kimberly J Saudino, Tracy L Nelson, Keith E Whitfield, Robin P Corley, Brooke M Huibregtse, Catherine A Derom, Robert F Vlietinck, Ruth J F Loos, Clare H Llewellyn, Abigail Fisher, Morten Bjerregaard-Andersen, Henning Beck-Nielsen, Morten Sodemann, Robert F Krueger, Matt McGue, Shandell Pahlen, Meike Bartels, Catharina E M van Beijsterveldt, Gonneke Willemsen, Jennifer R Harris, Ingunn Brandt, Thomas S Nilsen, Jeffrey M Craig, Richard Saffery, Lise Dubois, Michel Boivin, Mara Brendgen, Ginette Dionne, Frank Vitaro, Claire M A Haworth, Robert Plomin, Gombojav Bayasgalan, Danshiitsoodol Narandalai, Finn Rasmussen, Per Tynelius, Adam D Tarnoki, David L Tarnoki, Syuichi Ooki, Richard J Rose, Kirsi H Pietiläinen, Thorkild I A Sørensen, Dorret I Boomsma, Jaakko Kaprio, Karri Silventoinen
Background: The genetic architecture of birth size may differ geographically and over time. We examined differences in the genetic and environmental contributions to birthweight, length and ponderal index (PI) across geographical-cultural regions (Europe, North America and Australia, and East Asia) and across birth cohorts, and how gestational age modifies these effects. Methods: Data from 26 twin cohorts in 16 countries including 57 613 monozygotic and dizygotic twin pairs were pooled...
May 19, 2018: International Journal of Epidemiology
https://www.readbyqxmd.com/read/29781646/emotional-clarity-development-and-psychosocial-outcomes-during-adolescence
#14
Liza M Haas, Brae Anne McArthur, Taylor A Burke, Thomas M Olino, Lyn Y Abramson, Lauren B Alloy
Past research on emotional clarity (EC), the ability to identify and label one's own emotions, has illustrated an association between EC deficits and poor psychosocial outcomes during the adolescent years. Although past research has connected EC to psychosocial outcomes during adolescence in cross-sectional and longitudinal designs, no studies have traced the trajectory of EC over time to determine the developmental course of the construct during adolescence. Thus, this study investigated how EC developed over five years during adolescence and what factors were associated with the developmental trajectory of emotional clarity...
May 21, 2018: Emotion
https://www.readbyqxmd.com/read/29781470/neuro-oncology-nurse-navigation-developing-the-role-for-a-unique-patient-population
#15
Eleanor Miller
Navigation seeks to assess and address barriers that hinder a patient's access to care. With the success of the nurse navigation program at Penn Medicine's Abramson Cancer Center, leadership expanded navigation to neuro-oncology. The purpose of this article is to describe this population's unique needs and the effect of nurse navigation. Although the navigation role maintains integrity with regard to scope of practice, specialized navigation strategies are tailored to the neuro-oncology population and are different from other disease sites...
June 1, 2018: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/29750695/proximal-versus-distal-continuous-adductor-canal-blocks-does-varying-perineural-catheter-location-influence-analgesia-a-randomized-subject-masked-controlled-clinical-trial
#16
Jacklynn F Sztain, Bahareh Khatibi, Amanda M Monahan, Engy T Said, Wendy B Abramson, Rodney A Gabriel, John J Finneran, Richard H Bellars, Patrick L Nguyen, Scott T Ball, Francis B Gonzales, Sonya S Ahmed, Michael C Donohue, Jennifer A Padwal, Brian M Ilfeld
BACKGROUND: A continuous adductor canal block provides analgesia after surgical procedures of the knee. Recent neuroanatomic descriptions of the thigh and knee led us to speculate that local anesthetic deposited in the distal thigh close to the adductor hiatus would provide superior analgesia compared to a more proximal catheter location. We therefore tested the hypothesis that during a continuous adductor canal nerve block, postoperative analgesia would be improved by placing the perineural catheter tip 2-3 cm cephalad to where the femoral artery descends posteriorly to the adductor hiatus (distal location) compared to a more proximal location at the midpoint between the anterior superior iliac spine and the superior border of the patella (proximal location)...
May 9, 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29746555/human-herpes-virus-8-in-hiv-1-infected-individuals-receiving-cancer-chemotherapy-and-stem-cell-transplantation
#17
Louise E Hogan, Emily Hanhauser, Kristen S Hobbs, Christine D Palmer, Yvonne Robles, Stephanie Jost, Anne S LaCasce, Jeremy Abramson, Ayad Hamdan, Francisco M Marty, Daniel R Kuritzkes, Timothy J Henrich
BACKGROUND: Human Herpes Virus 8 (HHV8) can cause Kaposi's Sarcoma (KS) in immunosuppressed individuals. However, little is known about the association between chemotherapy or hematopoietic stem cell transplantation (HSCT), circulating HHV8 DNA levels, and clinical KS in HIV-1-infected individuals with various malignancies. Therefore, we examined the associations between various malignancies, systemic cancer chemotherapy, T cell phenotypes, and circulating HHV8 DNA in 29 HIV-1-infected participants with concomitant KS or other cancer diagnoses...
2018: PloS One
https://www.readbyqxmd.com/read/29736261/choroidal-infarction-following-ophthalmic-artery-chemotherapy
#18
Kelley J Bohm, Y Pierre Gobin, Jasmine H Francis, Gabrielle McInerney, Anahita Dabo-Trubelja, Paul H Dalecki, Brian P Marr, David H Abramson
Background: Methylenetetrahydrofolate reductase (MTHFR) genetic mutations and intra-procedural inhaled nitrous oxide (N2 O) independently increase blood levels of homocysteine, a compound associated with thrombosis. Patients with MTHFR mutations who also receive N2 O during ophthalmic artery chemotherapy (OAC) for retinoblastoma may have a heightened thrombotic risk. Case presentations: Single-center retrospective review of pediatric patients with advanced retinoblastoma who received OAC and developed choroidal infarcts...
2018: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/29734385/growth-patterns-of-survivors-of-retinoblastoma-treated-with-ophthalmic-artery-chemosurgery
#19
Sruti S Akella, Jasmine H Francis, Andrea Knezevic, Irina Ostrovnaya, Y Pierre Gobin, Danielle Friedman, Edith Guarini, Lindsey Eibeler, Federica Catalanotti, David H Abramson
Although studies from pediatric cancers (largely acute lymphoblastic leukemia) have shown that patients undergoing systemic chemotherapy may experience decreased growth velocity during the treatment phase, no such data exist for retinoblastoma patients treated with systemic chemotherapy or ophthalmic artery chemosurgery (OAC). The purpose of this study is to report growth patterns of our retinoblastoma (Rb) population who were treated with OAC in a retrospective, single center (Memorial Sloan Kettering Cancer Center) review of 341 patients treated between 2006 and 2016...
2018: PloS One
https://www.readbyqxmd.com/read/29727172/quantitative-prediction-of-optical-absorption-in-molecular-solids-from-an-optimally-tuned-screened-range-separated-hybrid-functional
#20
Arun K Manna, Sivan Refaely-Abramson, Anthony Martin Reilly, Alexandre Tkatchenko, Jeffrey B Neaton, Leeor Kronik
We show that fundamental gaps and optical spectra of molecular solids can be predicted quantitatively and non-empirically within the framework of time-dependent density functional theory (TDDFT), using the recently-developed optimally-tuned screened range-separated hybrid (OTSRSH) approach. In this scheme, the electronic structure of the gas-phase molecule is determined by optimal tuning of the range-separation parameter in a range-separated hybrid functional. Screening and polarization in the solid-state are taken into account by adding long-range dielectric screening to the functional form, with the modified functional used to perform self-consistent periodic-boundary calculations for the crystalline solid...
May 4, 2018: Journal of Chemical Theory and Computation
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