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https://www.readbyqxmd.com/read/29458197/changes-in-motor-function-cognition-and-emotion-related-behavior-after-right-hemispheric-intracerebral-hemorrhage-in-various-brain-regions-of-mouse
#1
Wei Zhu, Yufeng Gao, Jieru Wan, Xi Lan, Xiaoning Han, Shanshan Zhu, Weidong Zang, Xuemei Chen, Wendy Ziai, Daniel F Hanley, Scott J Russo, Ricardo E Jorge, Jian Wang
Intracerebral hemorrhage (ICH) is a detrimental type of stroke. Mouse models of ICH, induced by collagenase or blood infusion, commonly target striatum, but not other brain sites such as ventricular system, cortex, and hippocampus. Few studies have systemically investigated brain damage and neurobehavioral deficits that develop in animal models of ICH in these areas of the right hemisphere. Therefore, we evaluated the brain damage and neurobehavioral dysfunction associated with right hemispheric ICH in ventricle, cortex, hippocampus, and striatum...
February 16, 2018: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/29458184/defuse-3-reinforcing-evidence-for-extended-endovascular-intervention-time-window-for-ischemic-stroke
#2
Dallas L Sheinberg, David J McCarthy, Eric C Peterson, Robert M Starke
No abstract text is available yet for this article.
February 16, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29458183/age-dependent-attitudes-of-ischemic-patients-towards-disability-after-decompressive-hemicraniectomy-for-malignant-middle-cerebral-artery-infarction
#3
Byoung-Joon Kim, Yeon Ran Hong, Youngmin Han, Yang-Ha Hwang, Boram Ohk, Jaechan Park
OBJECTIVE: To improve the process of surgical informed consent, patient attitudes towards acceptable levels of disability after decompressive surgery for malignant middle cerebral artery infarction are investigated, including the impact of patient age. METHODS: Patients who had experienced a recent minor stroke were asked to complete a questionnaire comprised of 2 parts: 1) demographic information, including patient age, gender, years of education, working status, religion, and economic status and 2) acceptable level of disability based on a modified Rankin Scale (mRS) with corresponding illustrations to explain the mRS levels...
February 16, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29458135/porcine-heart-interatrial-septum-anatomy
#4
Mateusz K Hołda, Mateusz Koziej, Katarzyna Piątek, Wiesława Klimek-Piotrowska
BACKGROUND: The left-sided atrial septal pouch (SP), a recently re-discovered anatomical structure within the human interatrial septum, has emerged as a possible source of thrombi formation and a trigger for atrial fibrillation, thereby potentially increasing the risk for ischemic stroke. In many studies, the swine interatrial septum has been used as model of the human heart. Also, possible new strategies and devices for management of the SPs may first be tested in this pig model. Therefore, in this study, we aimed to evaluate swine interatrial septum morphology and to compare it with the human analog, especially in the light of SP occurrence...
February 16, 2018: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://www.readbyqxmd.com/read/29458073/establishment-and-validation-of-a-prediction-model-for-ischemic-stroke-risks-in-patients-with-type-2-diabetes
#5
Tsai-Chung Li, Hsiang-Chi Wang, Chia-Ing Li, Chiu-Shong Liu, Wen-Yuan Lin, Chih-Hsueh Lin, Sing-Yu Yang, Cheng-Chieh Lin
AIMS: A risk scoring system for predicting ischemic stroke incidence may identify type 2 diabetes patients at high risk for ischemic stroke who can benefit from preventive intervention programs. Such a risk scoring system can serve as a benchmark to test novel putative risk factors. METHODS: The study adopted a retrospective cohort, including 28,124 Chinese patients with type 2 diabetes aged 30-84 years during 2001-2004. Participants were randomly assigned to the derivation and validation sets at a 2:1 ratio...
February 16, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29458056/alcohol-and-cv-health-jekyll-and-hyde-j-curves
#6
REVIEW
Evan L O'Keefe, James J Di Nicolantonio, James H O'Keefe, Carl J Lavie
A routine of light or moderate alcohol consumption (≤1 drink/day for women and 1 to 2 drinks/day for men) were associated with a lower risk for all-cause mortality, coronary artery disease (CAD), type 2 diabetes mellitus (T2D), heart failure (HF), and stroke. Conversely, heavy drinking, (>4 drinks/day) is associated with an increased risk for death and cardiovascular (CV) disease (CVD). Excessive alcohol intake trails behind only smoking and obesity among the 3 leading causes of premature deaths in the United States (US)...
February 16, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/29457918/quality-of-life-among-patients-during-subacute-phase-following-stroke-during-hospitalisation-period-in-shanghai
#7
Jiang Jingwen, Jin Han, Zhang Yu, Huang Xiaojun, Zhuang Junpeng, Shen Fanxia, Liu Jianrong
OBJECTIVE: This study aimed to investigate the factors influencing the quality of life of in-hospital subacute stroke patients. METHODS: The patients of subacute stroke (within four weeks) in our institution between 2015 and 2016 were recruited. Patients' characteristics and QOL were obtained from medical charts and stroke-specific quality of life scale (SS-QOL). Associations of each domain in SS-QOL with socio-demographic, clinical factors and patient satisfaction were investigated using the linear regression models...
February 19, 2018: International Journal of Psychiatry in Clinical Practice
https://www.readbyqxmd.com/read/29457651/progressive-recruitment-of-contralesional-cortico-reticulospinal-pathways-drives-motor-impairment-post-stroke
#8
Jacob G McPherson, Albert Chen, Michael D Ellis, Jun Yao, C J Heckman, Julius P A Dewald
KEY POINTS: Activation of the shoulder abductor muscles in the arm opposite a unilateral brain injury causes involuntary increases in elbow, wrist and finger flexion in the same arm, a phenomenon referred to as the flexion synergy. It has been proposed that flexion synergy expression is related to reduced output from ipsilesional motor cortex and corticospinal pathways. In this human subjects study, we provide evidence that the magnitude of flexion synergy expression is instead related to a progressive, task-dependent recruitment of contralesional cortex...
February 19, 2018: Journal of Physiology
https://www.readbyqxmd.com/read/29457559/functional-outcomes-of-inpatient-rehabilitation-in-very-elderly-patients-with-stroke-differences-across-three-age-groups
#9
Hitoshi Mutai, Tomomi Furukawa, Ayumi Wakabayashi, Akihito Suzuki, Tokiji Hanihara
Background As the population continues to age rapidly, clarifying the factors affecting the prognosis in very elderly stroke patients is essential to enhance the quality of their rehabilitation. Objectives To compare the functional recovery of elderly stroke patients classified into three age groups and to identify the predictors of functional recovery in the very elderly following acute inpatient rehabilitation. Methods Observational study: We collected data on 461 stroke patients in the neurology and neurosurgery ward and classified them into three age groups (65-74, 75-84, and ≥ 85 years)...
February 19, 2018: Topics in Stroke Rehabilitation
https://www.readbyqxmd.com/read/29457532/effects-of-real-time-gait-biofeedback-on-paretic-propulsion-and-gait-biomechanics-in-individuals-post-stroke
#10
Katlin Genthe, Christopher Schenck, Steven Eicholtz, Laura Zajac-Cox, Steven Wolf, Trisha M Kesar
Objectives Gait training interventions that target paretic propulsion induce improvements in walking speed and function in individuals post-stroke. Previously, we demonstrated that able-bodied individuals increase propulsion unilaterally when provided real-time biofeedback targeting anterior ground reaction forces (AGRF). The purpose of this study was to, for the first time, investigate short-term effects of real-time AGRF gait biofeedback training on post-stroke gait. Methods Nine individuals with post-stroke hemiparesis (6 females, age = 54 ± 12...
February 19, 2018: Topics in Stroke Rehabilitation
https://www.readbyqxmd.com/read/29457494/management-of-phenobarbital-and-apixaban-interaction-in-recurrent-cardioembolic-stroke
#11
Philip K King, Trevor A Stump, Allyn M Walkama, Benjamin M Ash, Susana M Bowling
No abstract text is available yet for this article.
February 1, 2018: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/29457348/fixed-dose-vs-free-dose-combinations-for-the-management-of-hypertension-an-analysis-of-81-958-patients
#12
Peter Bramlage, Stefanie Schmidt, Helen Sims
Fixed-dose combinations (FDC) have been developed to reduce the pill burden for hypertensive patients. Data on fixed-dose or free-dose (freeDC) ramipril/amlodipine (R/A) or candesartan/amlodipine (C/A) combination treatment initiation were assessed. 71 463 patients were prescribed R/A and 10 495 C/A. For both R/A and C/A, FDC patients were younger (both P < .001) and less comorbid. Prior MI (OR: 0.61 and 0.60), prior stroke (OR: 0.68 and 0.70) and CHD (OR: 0.68 and 0.64) were negatively associated with FDC use, whereas hyperlipidemia was positively associated (OR: 1...
February 19, 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/29457323/anticoagulation-knowledge-in-patients-with-atrial-fibrillation-an-australian-survey
#13
Kehinde O Obamiro, Leanne Chalmers, Kenneth Lee, Bonnie J Bereznicki, Luke R E Bereznicki
BACKGROUND: Atrial fibrillation (AF) is the most commonly diagnosed arrhythmia in clinical practice, and is associated with a significant medical and economic burden. Anticoagulants reduce the risk of stroke and systemic embolism by approximately two-thirds compared with no therapy. Knowledge regarding anticoagulant therapy can influence treatment outcomes in patients with AF. OBJECTIVE: To measure the level of anticoagulation knowledge in patients with AF taking oral anticoagulants (OACs), investigate the association between patient-related factors and anticoagulation knowledge, and compare these results in patients taking warfarin and direct-acting oral anticoagulant (DOACs)...
February 19, 2018: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/29457264/comparison-of-left-atrial-size-and-function-in-hypertrophic-cardiomyopathy-and-in-fabry-disease-with-left-ventricular-hypertrophy
#14
María Cristina Saccheri, Tomás Francisco Cianciulli, Wilde Challapa Licidio, Jorge A Lax, Martín A Beck, Luis A Morita, Juan A Gagliardi
BACKGROUND: Fabry disease (FD) and hypertrophic cardiomyopathy (HCM) are two diseases with a different pathophysiology, both cause left ventricular hypertrophy (LVH) and myocardial fibrosis. Although remodeling and systolic dysfunction of the left atrium (LA) are associated with atrial fibrillation and stroke in HCM, changes in the size and function of the LA have not been well studied in FD with LVH. METHODS: The following groups were studied prospectively, and their respective findings compared: 19 patients with non-obstructive HCM (Group I), 20 patients with a diagnosis of Fabry cardiomyopathy (Group II), and 20 normal subjects matched for sex and age (Group III)...
February 19, 2018: Echocardiography
https://www.readbyqxmd.com/read/29457261/angiography-vs-transesophageal-echocardiography-guided-patent-foramen-ovale-closure-a-propensity-score-matched-analysis-of-a-two-center-registry
#15
Paolo Scacciatella, Ilaria Meynet, Mauro Giorgi, Lorenza M Biava, Ivana Matranga, Luigi Biasco, Pierluigi Omedè, Fulvio Orzan, Fiorenzo Gaita
OBJECTIVES: The purpose of this study is to compare the long-term outcomes of patent foramen ovale (PFO) closure using angiography or transesophageal echocardiography as procedural guidance. BACKGROUND: The interventional treatment is emerging as a safe and efficient option for patients with high likelihood of PFO-related cryptogenic stroke and high risk of recurrence. The "gold-standard" guidance technique remains an issue. METHODS: Two cohorts of patients undergoing PFO closure for cryptogenic stroke in two catheterization laboratories of the same institution, using similar inclusion criteria but different guidance, were compared with propensity score matching...
February 19, 2018: Echocardiography
https://www.readbyqxmd.com/read/29457147/a-scoping-review-of-health-outcomes-examined-in-randomized-controlled-trials-using-guided-imagery
#16
Peter R Giacobbi, Jonathan Stewart, Keeley Chaffee, Anna-Marie Jaeschke, Meagan Stabler, George A Kelley
Introduction: Guided imagery involves the controlled visualization of detailed mental images. This integrative health technique is used for healing, health maintenance, or the treatment of specific conditions. Guided imagery is an integral part of mindfulness meditation, hypnosis, and various relaxation exercises. However, evidence to support the widespread use and dissemination of guided imagery interventions has been lacking. The purposes of this scoping review were to document the scope of health outcomes and disease processes examined by guided imagery researchers and the journal outlets where this work has been published...
December 2017: Progress in Preventive Medicine
https://www.readbyqxmd.com/read/29456567/influence-of-blood-glucose-level-on-the-prognosis-of-patients-with-diabetes-mellitus-complicated-with-ischemic-stroke
#17
REVIEW
Xiao-Liu Dong, Fei Guan, Shi-Jun Xu, Li-Xia Zhu, Pan-Pan Zhang, Ai-Bin Cheng, Tie-Jun Liu
We carried out this meta-analysis for the aim of exploring the influence of diabetes mellitus (DM) on the prognosis of patients with ischemic stroke. Relevant studies were identified using computerized databases supplemented with manual search strategies. The included studies were strictly followed the inclusion and exclusion criteria. Case-control studies which related to the influence of DM on the prognosis of patients with ischemic stroke were selected. Statistical analyses were implemented with the STATA version 12...
2018: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/29456400/unilateral-transient-watershed-cerebral-infarct-in-a-6-year-old-girl-with-frequently-relapsing-nephrotic-syndrome
#18
Kapil Bhalla, Deepali Garg, Mahima Rajan, Jaya Shankar Kaushik, Geeta Gathwala
Nephrotic syndrome is a prothrombotic state with predisposition to venous sinus thrombosis and arterial vascular stroke. Watershed infarcts in junction of arterial territory develop in hypotensive hypovolemic state. These border zone infarcts are usually bilateral in the absence of unilateral arterial stenosis or microembolism. We report a 6-year-girl of frequently relapsing nephrotic syndrome who developed sudden onset hemiparesis with aphasia. Magnetic resonance (MR) imaging brain revealed unilateral watershed infarct in territory between the major cerebral arterial vessels with evidence of restricted diffusion and normal vessel anatomy on MR angiography...
January 2018: Journal of Natural Science, Biology, and Medicine
https://www.readbyqxmd.com/read/29456380/moxibustion-artemisia-plant-at-acupuncture-point-as-alternative-therapy-in-hypertension-a-promising-approach
#19
Mohammad Jamshed Siddiqui, Mohamad Fadly Bin Kamarudin, Abdul Kareem Mohammed Al-Shami, Siti Zaiton Mat So'ad, Shazia Qasim Jamshed
Hypertension is a pathological condition in which the blood pressure is higher than under normal physiological conditions, i.e., 140/90 mmHg or higher. Blood pressure is measured as the force exerted by the blood pumped by the heart against the walls of arteries (aorta) and distributed throughout the body. Use of complementary and alternative medicine as a cure for hypertension is a common phenomenon because of the high risk of cardiovascular complications and kidney diseases caused by conventional Western medicine...
October 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29456365/dyspraxic-gait-due-to-right-posterior-cerebral-artery-stroke
#20
Halil Onder
No abstract text is available yet for this article.
January 2018: Journal of Neurosciences in Rural Practice
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