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Isotretinoin

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https://www.readbyqxmd.com/read/29469597/treatment-of-multiple-eccrine-hidrocystoma-with-oral-isotretinoin-following-erbium-yttrium-aluminum-garnet-laser
#1
Serkan Demirkan
Eccrine hidrocystomes (EH) are benign cystic tumors of dermal eccrine ducts. There is still no gold standard treatment option for EH because of the large number of lesions, the risk of cicatrization and the different treatment options offered. We offer combined oral isotretinoin and following erbium-yttrium aluminum garnet laser treatment as an alternative treatment option in difficult patients with EH.
February 22, 2018: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/29464980/evaluation-the-efficacy-of-trichloroacetic-acid-tca-33-in-treatment-of-oral-retinoid-induced-cheilitis-compared-with-placebo-vaseline-a-randomized-pilot-study
#2
Parvin Mansouri, Zahra Azizian, Zeinab Najafi, Somaye Hejazi, Shima Younespour
BACKGROUND: Oral Isotretinoin (13-cis-retinoic acid)is a gold standardtreatment for severe forms of acne with cheilitis as a most frequent complication.we designed this novel study to investigate the therapeutic effect of Trichloroacetic Acid(TCA) 33% as compared with placebo to treat cheilitis. METHODS: In this pilot study, 90 acne vulgaris patients between 18 to 50 years, who refered dermatologic clinic with cheilitis, were assigned to either case (TCA) or control (Vaseline) group using permuted-block randomization from 2013 to 2015,with data analysis in 2016...
February 21, 2018: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/29460332/vitamin-d-levels-in-acne-vulgaris-patients-treated-with-oral-isotretinoin
#3
Mohammed Abu El-Hamd, Moustafa A El Taieb, Hassan M Ibrahim, Sanaa S Aly
BACKGROUND/OBJECTIVES: Acne vulgaris is a common inflammatory skin disease. Vitamin D deficiency plays a role in many inflammatory skin diseases. It may play a role in pathogenesis of acne vulgaris. This study aimed to assess serum levels of 25 hydroxy vitamin D in patients with acne vulgaris before and after treatment with isotretinoin and its relation with acne vulgaris severity. METHODS: Ninety patients with acne vulgaris and 60 age-sex matched healthy subject as controls have been recruited in this study...
February 20, 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29441308/granulomatous-periorificial-dermatitis-effectively-managed-with-oral-isotretinoin
#4
Swagata Tambe, Hemangi Jerajani, Poonam Pund
No abstract text is available yet for this article.
January 2018: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/29417084/comparing-the-efficacy-of-low-dose-and-conventional-dose-of-oral-isotretinoin-in-treatment-of-moderate-and-severe-acne-vulgaris
#5
Gita Faghihi, Fatemeh Mokhtari, Nasrin Motamedi Fard, Narges Motamedi, Sayed Mohsen Hosseini
Objective: This study was conducted to compare the effect of low-dose isotretinoin with its conventional dose in patients with moderate and severe acne. Methods: This was a clinical trial conducted on 60 male and female patients with moderate and severe acne vulgaris. The patients were divided into two treatment groups: 0.5 mg/kg/day isotretinoin capsule and low-dose isotretinoin capsule (0.25 mg/kg/day). Patients in both groups received 6-month treatment. At the end of the 6th month and 12th month (6 months after the end of the treatment), they were examined again, and their improvement was determined and compared...
October 2017: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/29409107/indications-and-use-of-isotretinoin-in-facial-plastic-surgery
#6
Markus V Heppt, Michael C Kirchberger, Thomas Ruzicka, Carola Berking, Werner J Heppt
Isotretinoin is a first generation retinoid with pleiotropic effects on keratinocyte differentiation, proliferation, and activity of sebaceous glands. For years, there has been intense debate on whether the use of isotretinoin combined with cosmetic or surgical procedures is safe and potentially more efficient than either therapy alone. Due to delays in wound healing and keloid formation, conservative recommendations were not to combine isotretinoin with any plastic surgery or local treatment at 6 to 12 months after discontinuation of the drug...
February 2018: Facial Plastic Surgery: FPS
https://www.readbyqxmd.com/read/29403267/assessment-of-medication-adherence-and-responsible-use-of-isotretinoin-and-contraception-through-belgian-community-pharmacies-by-using-pharmacy-refill-data
#7
Natacha Biset, Mélanie Lelubre, Christelle Senterre, Karim Amighi, Olivier Bugnon, Marie P Schneider, Carine De Vriese
Purpose: The aims of the study were to evaluate medication adherence and the influencing factors for isotretinoin and contraception (oral, patches, and rings) and to evaluate the concomitant use of contraception and isotretinoin. Methods: Reimbursed prescription data from January 2012 to August 2015 of all patients in Belgium were received from Pharmanet-National Institute for Health and Disability Insurance. Medication adherence was measured according to the medication possession ratio...
2018: Patient Preference and Adherence
https://www.readbyqxmd.com/read/29395031/facial-papules-in-frontal-fibrosing-alopecia-good-response-to-isotretinoin
#8
M Á Flores-Terry, M García-Arpa, M Franco-Muñóz, L González-Ruiz
No abstract text is available yet for this article.
January 22, 2018: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/29369339/prevalence-and-predictors-of-depressive-symptoms-among-attendees-of-a-tertiary-care-dermatology-clinic-in-muscat-oman
#9
Mohammed Al Alawi, Hamed Al Sinawi, Al Mutasim Al Qasabi, Al Moatasem Al Mamari, Sathiya Murthi Panchatcharam, Samir Al-Adawi
BACKGROUND: Various studies have suggested that depression is more prevalent among patients with skin disorders than in the general population. Most of the studies addressing this subject involve Euro-American populations. OBJECTIVES: The present study aimed to estimate the prevalence of depressive symptoms among patients with dermatological disorders and, then, to decipher the clinical-demographic factors associated with depressive symptoms. METHODS: A cross-sectional analytical study was conducted among a random sample of patients attending a dermatology clinic in Muscat...
January 25, 2018: International Journal of Dermatology
https://www.readbyqxmd.com/read/29364446/morbihan-disease-a-therapeutic-challenge
#10
Fernanda Cabral, Lara Caroline Lubbe, Monisa Martins Nóbrega, Daniel Lago Obadia, Roberto Souto, Alexandre Carlos Gripp
Morbihan disease is a rare condition characterized by chronic and persistent erythematous solid edema localized on the face. It is believed to be a complication of rosacea and may occur at any stage of the disease. Features of this condition include variable therapeutic response and great refractoriness. We report a case of a 61-year-old man with rosacea history diagnosed with Morbihan disease, who showed excellent therapeutic response with the combination of deflazacort and oral isotretinoin but developed recurrence after corticosteroid discontinuation...
November 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/29363297/teratogenicity-of-systemic-isotretinoin
#11
Helle Holst, Edit Muhari-Stark, Sebastiano A Lava
No abstract text is available yet for this article.
February 2018: Minerva Pediatrica
https://www.readbyqxmd.com/read/29362686/a-possible-link-between-pyriproxyfen-and-microcephaly
#12
Raphael Parens, H Frederik Nijhout, Alfredo Morales, Felipe Xavier Costa, Yaneer Bar-Yam
The Zika virus has been the primary suspect in the large increase in incidence of microcephaly in 2015-6 in Brazil. While evidence for Zika being the cause of some of the cases is strong, its role as the primary cause of the large number of cases in Brazil has not been confirmed. Recently, the disparity between the incidences in different geographic locations has led to questions about the virus's role. Here we consider the alternative possibility that the use of the insecticide pyriproxyfen for control of mosquito populations in Brazilian drinking water is the primary cause...
November 27, 2017: PLoS Currents
https://www.readbyqxmd.com/read/29360905/disfiguring-ulcerative-neutrophilic-dermatosis-secondary-to-doxycycline-and-isotretinoin-in-an-adolescent-boy-with-acne-conglobata
#13
Bahman Sotoodian, Paul Kuzel, Alain Brassard, Loretta Fiorillo
Acne fulminans is an uncommon and debilitating disease that presents as an acute eruption of nodular and ulcerative acne lesions in association with systemic symptoms. It occurs commonly during treatment of severe acne (eg, acne conglobata) with isotretinoin in young adolescent male patients. Isotretinoin and doxycycline also can potentially induce development of neutrophilic dermatoses in patients with severe acne lesions, which are characterized by the acute appearance of painful ulcerative papulonodules accompanied by systemic symptoms including fever and leukocytosis...
December 2017: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/29332721/oral-isotretinoin-as-an-adjunctive-treatment-for-recurrent-genital-warts
#14
Abhijeet Kumar Jha, Sidharth Sonthalia, Satyaki Ganguly
No abstract text is available yet for this article.
February 2018: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29314240/isotretinoin-induced-acne-fulminans-without-systemic-symptoms-with-concurrent-exuberant-granulation-tissue
#15
Alvin W Li, Richard J Antaya
Acne fulminans is a severe form of acne characterized by painful, inflammatory nodules that progress into ulcers and concurrent systemic symptoms. Treatment of acne with isotretinoin can precipitate a syndrome called isotretinoin-induced acne fulminans without systemic symptoms. An exuberant granulation tissue response, another known adverse event associated with isotretinoin, can occur concurrently, inhibiting wound repair and complicating treatment. We report a case of isotretinoin-induced acne fulminans without systemic symptoms with exuberant granulation tissue response that was treated successfully with topical clobetasol ointment...
January 4, 2018: Pediatric Dermatology
https://www.readbyqxmd.com/read/29313960/isotretinoin-treatment-for-folliculitis-decalvans-a-retrospective-case-series-study
#16
Berna Aksoy, Asli Hapa, Emine Mutlu
BACKGROUND: The literature includes only a few reports of oral isotretinoin for the treatment of folliculitis decalvans (FD). This study aimed to determine the most effective dose and duration of oral isotretinoin monotherapy for achieving remission in FD patients. METHODS: This retrospective case series study included FD patients that were treated with oral isotretinoin. Patient demographics, clinical characteristics, and treatment details were obtained from the patients' medical records...
February 2018: International Journal of Dermatology
https://www.readbyqxmd.com/read/29308367/retinoic-acid-embryopathy
#17
Dipankar Mondal, Sreekanth R Shenoy, Santisena Mishra
Isotretinoin is a retinoid which is derived from Vitamin A. It is indicated for severe cystic acne treatment, but it has been classified as teratogenic. A wide spectrum of birth defects including craniofacial, heart, and nervous system malformations have been described with prenatal exposure to this drug. We report the case of a newborn with a history of prenatal exposure to isotretinoin with craniofacial defects, including left-sided anotia, right-sided microtia, complex congenital heart disease, and central nervous system malformation...
October 2017: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/29285959/kyrle-s-disease-effectively-treated-with-oral-isotretinoin
#18
Martina Maurelli, Paolo Gisondi, Giampiero Girolomoni
BACKGROUND: Kyrle's disease (KD) is a primary perforating dermatosis that affects more commonly 30-50 year old females, and clinically characterized by pruritic hyperkeratotic and ulcerated nodules, papules and plaques, localized on extensor surface of upper and lower limbs, and on the trunk. OBJECTIVE: To determine the effectiveness of the treatment with oral isotretinoin in KD. METHODS: We present the case of a 63-year-old woman with hyperkeratotic, erythematous-brown nodules and plaques localized on arms and legs, intensely itching; some lesions were ulcerated and discharging...
January 10, 2018: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/29282392/diffuse-dermal-angiomatosis-of-the-breast-a-distinct-entity-in-the-spectrum-of-cutaneous-reactive-angiomatoses-clinicopathologic-study-of-two-cases-and-comprehensive-review-of-the-literature
#19
Jörg Galambos, Claudia Meuli-Simmen, Regula Schmid, Lisa S Steinmann, Werner Kempf
Diffuse dermal angiomatosis (DDA) is a rare reactive angioproliferation in the skin and considered to be a subtype in the group of cutaneous reactive angiomatoses. DDA is clinically characterized by livedoid patches and plaques with tender ulceration. Its histologic features are a reactive diffuse proliferation of bland endothelial cells and pericytes within the dermis, forming small capillary vessels. Previously described cases of DDA most commonly involved the limbs and were associated with a wide spectrum of predisposing comorbidities, especially advanced atherosclerotic vascular disease and arteriovenous fistula...
September 2017: Case Reports in Dermatology
https://www.readbyqxmd.com/read/29249250/-what-s-new-in-pediatric-dermatology
#20
C Chiaverini
The year 2017 in pediatric dermatology was marked by several consensus recommendations and meta analyzes on childhood psoriasis, atopic dermatitis or PHACE syndrome, case series on the role of anti-JAK treatment in adolescent with alopecia areata, sirolimus for vascular malformations, ivermectine for rosacea, inhibitors of MEK for type 1 neurofibromatosis or on the side effects of the oral isotretinoin for acne or propranolol for immature hemangioma. Only few randomized controlled studies have been published on the interest of adalimumab in the treatment of psoriasis or topical sirolimus for angiofibroma in tuberous sclerosis complex for example...
December 2017: Annales de Dermatologie et de Vénéréologie
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