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Antibiotic sensitivity

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https://www.readbyqxmd.com/read/28635967/social-behaviour-involving-drug-resistance-the-role-of-initial-density-initial-frequency-and-population-structure-in-shaping-the-effect-of-antibiotic-resistance-as-a-public-good
#1
I L Domingues, J A Gama, L M Carvalho, F Dionisio
Bacteria sometimes cooperate with co-inhabiting cells. Pathogenic bacteria, for example, often produce and excrete virulence factors, eventually benefitting both producer and non-producer cells. The role of social interactions involving antibiotic resistance, however, has been more elusive. Enzymes that inactivate β-lactam antibiotics such as ampicillin or penicillin (β-lactamases) are good candidates as public goods. Nonetheless, it has been claimed that bacteria harbouring plasmids of natural origin coding for β-lactamase almost do not protect sensitive bacteria...
June 21, 2017: Heredity
https://www.readbyqxmd.com/read/28634541/campylobacter-jejuni-myocarditis-a-journey-from-the-gut-to-the-heart
#2
M Toba Obafemi, Homeyra Douglas
OBJECTIVES: Campylobacter jejuni is an unusual cause of myocarditis and could easily be missed. METHODS: We describe a case of a 25 year old man, who presented with 3 day history of vomiting and diarrhoea, followed by chest pain and significant high sensitive troponin rise. RESULTS: The patient's profuse diarrhoea was accompanied by raised inflammatory markers, electrocardiogram changes and evidence of cardiomyopathy on transthoracic echocardiogram...
2017: SAGE open medical case reports
https://www.readbyqxmd.com/read/28634537/a-meta-analysis-of-antibacterial-envelope-use-in-prevention-of-cardiovascular-implantable-electronic-device-infection
#3
Sajid Ali, Yousuf Kanjwal, Steven R Bruhl, Mohammed Alo, Mohammed Taleb, Syed S Ali, Ameer Kabour, Owais Khawaja
OBJECTIVES: Cardiac implantable electronic device (CIED) infection has been a major clinical problem in addition to being a major financial burden. In spite of antimicrobial prophylaxis, CIED infection rates have been increasing disproportionately. We therefore conducted this meta-analysis to assess the role of TYRX antibiotic envelope for the prevention of CIED infection. METHODS: Using extensive online search, we conducted a meta-analysis of studies reporting CIED infections with versus without the use of TYRX antibiotic envelope...
May 2017: Therapeutic Advances in Infectious Disease
https://www.readbyqxmd.com/read/28633962/evaluation-of-three-commercial-multiplex-assays-for-the-detection-of-respiratory-viral-infections
#4
Sandi Radko, J Ian Stuart, George Zahariadis
BACKGROUND: Timely identification of respiratory virus infection is essential to mitigate inappropriate antibiotic use and to implement appropriate treatment and/or infection control procedures. As such, multiplexed PCR assays have become standard in many virology laboratories. OBJECTIVES: To compare the Seeplex RV15 (test of record) with two newer generation multiplex assays, the Anyplex II RV16 and the xTAG respiratory virus panels. STUDY DESIGN: Two hundred and three retrospective and 36 prospective respiratory samples were tested by all three assays...
June 17, 2017: Journal of Virological Methods
https://www.readbyqxmd.com/read/28632783/transient-effects-of-transfusion-and-feeding-advances-volumetric-and-caloric-on-necrotizing-enterocolitis-development-a-case-crossover-study
#5
Vi T Le, Mark A Klebanoff, Maria M Talavera, Jonathan L Slaughter
OBJECTIVE: To evaluate the short-term effects of feed fortification, feed volume increase, and PRBC transfusion on the odds of developing NEC. STUDY DESIGN: Case-crossover study of neonatal intensive care infants born at ≤ 32 weeks' gestation who were admitted to 5 central Ohio intensive care units from January 2012-July 2016 and developed NEC Bell Stage ≥2. Each patient served as their own control, with exposure during the 48-hour period just prior to NEC onset (hazard period) being compared to a preceding 48-hour control period, thus eliminating confounding by patient factors fixed between both intervals...
2017: PloS One
https://www.readbyqxmd.com/read/28632380/recent-progress-in-nanomaterial-based-optical-aptamer-assay-for-the-detection-of-food-chemical-contaminants
#6
Lingyi Lan, Yao Yao, Jianfeng Ping, Yibin Ying
Food chemical contaminant is a major factor to cause foodborne diseases and can do harm to human health. Hence, to develop robust, easy, and sensitive methods for rapid evaluation of food chemical contaminants is highly desirable. Nanomaterial-based optical aptasensors combined with the advantages of the high selectivity of optical detection techniques, excellent stability of aptamer, and the unique properties of nanomaterials have been recognized as useful tools for routine biosensing applications. The recent progress in nanomaterial-based optical aptamer assays to determine food chemical contaminants including heavy metals, toxins, pesticides, and antibiotics are presented in this paper...
June 20, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28631638/clinicomicrobiological-profile-of-endophthalmitis-a-10-year-experience-in-a-tertiary-care-center-in-north-india
#7
Gita Satpathy, Niranjan Nayak, Meenakshi Wadhwani, Pradeep Venkwatesh, Atul Kumar, Yograj Sharma, Vishnu Sreenivas
PURPOSE: To determine the clinicomicrobiological profile of infectious agents and their antibiotic susceptibility in different type of endophthalmitis. METHODS: A retrospective review of clinical and microbiological records from January 2001 to December 2010, was performed in 1110 patients diagnosed with different type of endophthalmitis (postoperative, posttraumatic, endogenous and post keratitis) to record the demographic details, clinical presentations; microbiological agents isolated with their antimicrobial sensitivity pattern...
April 2017: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/28631632/risk-of-cardiac-pacemaker-pocket-infection-in-a-tertiary-care-hospital
#8
Jaswinder Singh Gill, Navreet Singh, S P Khanna
BACKGROUND: The risk of pacemaker pocket infections (PPIs) is rare with good antisepsis techniques and use of advanced antibiotics. However, injudicious antibiotic usage leads to the rise of multidrug-resistant bacteria, which may cause PPI. Few reports exist about the microbial spectrum of the PPI from our country, prompting us to study the same. METHODS: We conducted this retrospective observational study for 3 years (January 2013-February 2016) from all the patients with PPI...
April 2017: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/28630127/deciphering-function-of-new-gonococcal-vaccine-antigens-using-phenotypic-microarrays
#9
Benjamin I Baarda, Sarah Emerson, Philip J Proteau, Aleksandra E Sikora
The function and extracellular location of cell envelope proteins make them attractive candidates for developing vaccines against bacterial diseases, including challenging, drug-resistant pathogens such as Neisseria gonorrhoeae Proteomics-driven reverse vaccinology delivered multiple gonorrhea vaccine candidates; however, the biological functions of many of them remain to be elucidated. Herein, the functions of six gonorrhea vaccine candidates - NGO2121, NGO1985, NGO2054, NGO2111, NGO1205, and NGO1344 - in cell envelope homeostasis were probed using phenotype microarrays with 1,056 conditions and a ΔbamE mutant (Δngo1780) as a reference of perturbed outer membrane integrity...
June 19, 2017: Journal of Bacteriology
https://www.readbyqxmd.com/read/28629795/epidemiological-features-and-antibiotic-resistance-patterns-of-haemophilus-influenzae-originating-from-respiratory-tract-and-vaginal-specimens-in-pediatric-patients
#10
Jian-Ping Li, Chun-Zhen Hua, Li-Ying Sun, Hong-Jiao Wang, Zhi-Min Chen, Shi-Qiang Shang
BACKGROUND: Haemophilus influenzae (H. influenzae) is a common pathogen of respiratory tract infections in children, however, as a possible cause of vulvovaginitis in prepubertal girls, its epidemiological features,antibiotic-resistance patterns, and treatment are seldom noted. METHODS: Specimens obtained from patients were inoculated on Haemophilus selective medium; and drug-sensitivities tests were determined with disc diffusion method. Cefinase disc was used to detect β-lactamase...
June 16, 2017: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/28629781/position-paper-for-the-evaluation-and-management-of-oral-status-in-patients-with-valvular-disease-groupe-de-travail-valvulopathies-de-la-soci%C3%A3-t%C3%A3-fran%C3%A3-aise-de-cardiologie-soci%C3%A3-t%C3%A3-fran%C3%A3-aise-de-chirurgie-orale-soci%C3%A3-t%C3%A3-fran%C3%A3-aise-de-parodontologie-et-d-implantologie
#11
REVIEW
Sarah Millot, Philippe Lesclous, Marie-Laure Colombier, Loredana Radoi, Clément Messeca, Mathieu Ballanger, Jean-Luc Charrier, Philippe Tramba, Stéphane Simon, Alain Berrebi, Fabien Doguet, Emmanuel Lansac, Christophe Tribouilloy, Gilbert Habib, Xavier Duval, Bernard Iung
Oral health is of particular importance in patients with heart valve diseases because of the risk of infective endocarditis. Recommendations for antibiotic prophylaxis before dental procedures have been restricted, but the modalities of oral evaluation and dental care are not detailed in guidelines. Therefore, a multidisciplinary working group reviewed the literature to propose detailed approaches for the evaluation and management of buccodental status in patients with valvular disease. Simple questions asked by a non-dental specialist may draw attention to buccodental diseases...
June 16, 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/28629687/sensitivity-and-specificity-of-empiric-treatment-for-sexually-transmitted-infections-in-a-pediatric-emergency-department
#12
Kristen Breslin, Lisa Tuchman, Katie L Hayes, Gia Badolato, Monika K Goyal
OBJECTIVE: To determine test characteristics of provider judgment for empiric antibiotic provision to patients undergoing testing for a sexually transmitted infection. STUDY DESIGN: We conducted a retrospective cross-sectional electronic health record review of all patients aged 13-19 years who had Neisseria gonorrhoeae (GC) and Chlamydia trachomatis (CT) testing sent from an urban, academic pediatric emergency department in 2012. We abstracted data, including patient demographics, chief complaint, sexually transmitted infection test results, and treatment...
June 16, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28629614/molecular-detection-methods-of-resistance-to-antituberculosis-drugs-in-mycobacterium-tuberculosis
#13
F Brossier, W Sougakoff
OBJECTIVE: Molecular methods predict drug resistance several weeks before phenotypic methods and enable rapid implementation of appropriate therapeutic treatment. We aimed to detail the most representative molecular tools used in routine practice for the rapid detection of resistance to antituberculosis drugs among Mycobacterium tuberculosis strains. MATERIALS AND METHODS: The molecular diagnosis of resistance to antituberculosis drugs in clinical samples or from in vitro cultures is based on the detection of the most common mutations in the genes involved in the development of resistance in M...
June 16, 2017: Médecine et Maladies Infectieuses
https://www.readbyqxmd.com/read/28627952/clinical-efficacy-of-piperacillin-tazobactam-in-the-treatment-of-complicated-skin-and-soft-tissue-infections
#14
Kohei Takimoto, Qianzhi Wang, Daisuke Suzuki, Mitsuya Katayama, Yoshiro Hayashi
Introduction Complicated skin and soft tissue infections (cSSTIs) are skin and soft tissue infections (SSTIs) that involve deep soft tissue. cSSTIs often require surgical intervention and/or hospitalization. cSSTIs are associated with significant mortality and morbidity, and carry a significant burden on health care systems. Piperacillin/tazobactam has been regarded as a standard treatment for cSSTIs because of its antibiotic spectrum, safety and clinical efficacy. Several antibiotics, as compared to piperacillin/tazobactam, have been evaluated in the treatment of cSSTIs...
June 19, 2017: Expert Opinion on Pharmacotherapy
https://www.readbyqxmd.com/read/28625839/surveillance-of-upper-respiratory-infections-by-using-newly-multiplex-pcr-assay-compared-to-conventional-methods-during-influenza-season-in-taiwan
#15
Shu-Chun Chiu, Yung-Cheng Lin, Hsiao-Chi Wang, Jen-Jen Hsu, Ting-Kai Yeh, Hsin-Fu Liu, Jih-Hui Lin
OBJECTIVES: To improve the diagnosis of laboratory surveillance, we conducted influenza-like illness (ILI) surveillance by using newly multiplex PCR Assay (FilmArray) compared to conventional methods during winter period in Taiwan. METHODS: Throat swabs from ILI patients presenting to physicians in sentinel practices were collected during 2016-2017 influenza season. RESULTS: A total of 52 samples were tested positive by FilmArray-Respiratory Panel, 40% of them were influenza A virus, subtype H3N2 viruses were the major epidemic strains...
June 15, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/28625182/bovine-intra-mammary-challenge-with-streptococcus-dysgalactiae-spp-dysgalactiae-to-explore-the-effect-on-the-response-of-complement-activity
#16
Susan Maye, James Flynn, Catherine Stanton, Gerald F Fitzgerald, Philip M Kelly
Recently published work as described by the authors highlighted the extent of Complement activity in bovine milk. Localised mastitis infection occurring in the mammary glands of dairy cows is readily detectable by the levels of somatic cells in milk. Thus, it is opportune to monitor Complement activity in milks in association with the animal's innate immune response to mammary infection. Preliminary screening of milk samples taken randomly showed that milk with a high somatic cell count (SCC) reduced growth of the Complement-sensitive strain E...
June 19, 2017: Journal of Dairy Research
https://www.readbyqxmd.com/read/28625025/-causative-bacterial-strains-and-sensitivityto-antimicrobial-agents-in-female-acute-uncomplicated-cystitis
#17
Takuya Owari, Tomoki Yamamoto, Shinichiro Mizobuchi, Yositaka Itami, Tomonori Nakahama, Yosihiro Matsumoto, Kaoru Yamada, Hitoshi Momose
Recently, wide spreading of fluoloquinolone resistant Escherichia coli is a serious problem inthe treatment of urinary tract infection. To investigate the causative bacterial strains of female acute uncomplicated cystitis (AUC) in the community and their sensitivity to antimicrobial agents, we retrospectively reviewed the medical records of 215 female AUC patients treated at our clinics from April 2014 to June 2015. Two hundred and nineteen strains were isolated as the causative bacteria from the patients'urine samples, including E...
May 2017: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/28623341/metabolic-fingerprinting-of-bacteria-by-fluorescence-lifetime-imaging-microscopy
#18
Arunima Bhattacharjee, Rupsa Datta, Enrico Gratton, Allon I Hochbaum
Bacterial populations exhibit a range of metabolic states influenced by their environment, intra- and interspecies interactions. The identification of bacterial metabolic states and transitions between them in their native environment promises to elucidate community behavior and stochastic processes, such as antibiotic resistance acquisition. In this work, we employ two-photon fluorescence lifetime imaging microscopy (FLIM) to create a metabolic fingerprint of individual bacteria and populations. FLIM of autofluorescent reduced nicotinamide adenine dinucleotide (phosphate), NAD(P)H, has been previously exploited for label-free metabolic imaging of mammalian cells...
June 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28622864/isolation-and-characterization-of-avibacterium-paragallinarum-with-different-nicotinamide-adenine-dinucleotide-requirements
#19
Ok-Mi Jeong, Min-Su Kang, Byung-Woo Jeon, Byung-Kook Choi, Yong-Kuk Kwon, So-Youn Yoon, Patrick J Blackall, Hee-Soo Lee, Suk-Chan Jung, Jae-Hong Kim
Twenty field isolates of Avibacterium paragallinarum were obtained from chickens in South Korea during 2011-2015. The isolates were identified by a HPG-2 PCR assay specific for A. paragallinarum and by biochemical tests. Growth requirements, Page serovars, carbohydrate fermentation patterns, and antimicrobial susceptibility were also examined. Most isolates (16/20) showed the typical requirement for nicotinamide adenine dinucleotide (NAD) and an enriched CO2 atmosphere for growth. One isolate needed increased levels of NAD and serum for good growth...
June 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/28621728/determination-of-sulfonamide-residues-in-food-by-capillary-zone-electrophoresis-with-on-line-chemiluminescence-detection-based-on-an-ag-iii-complex
#20
Tingting Dai, Jie Duan, Xinghua Li, Xiangdong Xu, Hongmei Shi, Weijun Kang
The presence of sulfonamide (SA) residues in foods is largely due to the raising of animals with sulfonamide antibiotics added or polluted feedstuff. In this paper, a sensitive method was developed for the determination of the residues of three sulfonamides in animal-derived food; the SAs include sulfadimidine (SDD), sulfadiazine (SDZ), and sulfathiazole (STZ). The method is based on capillary zone electrophoresis (CE) with online chemiluminescence (CL) detection, using an Ag(III) complex as an oxidant. These SAs have an inhibiting effect on the Ag(III)-luminol CL reaction...
June 16, 2017: International Journal of Molecular Sciences
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