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Supraspinatus

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https://www.readbyqxmd.com/read/28916838/functionally-distinct-tendons-from-elastin-haploinsufficient-mice-exhibit-mild-stiffening-and-tendon-specific-structural-alteration
#1
Jeremy D Eekhoff, Fei Fang, Lindsey G Kahan, M G Espinosa, Austin J Cocciolone, Jessica E Wagenseil, Robert P Mecham, Spencer P Lake
Elastic fibers are present in low quantities in tendon, where they are located both within fascicles near tenocytes and more broadly in the interfascicular matrix. While elastic fibers have long been known to be significant in the mechanics of elastin-rich tissue (i.e. vasculature, skin, lungs), recent studies have suggested a mechanical role for elastic fibers in tendons that is dependent on specific tendon function. However, the exact contribution of elastin to properties of different types of tendons (e...
September 16, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28910993/transtendon-repair-in-partial-articular-supraspinatus-tendon-tear
#2
Leonardo Osti, Matteo Buda, Mattia Andreotti, Raffaella Osti, Leo Massari, Nicola Maffulli
Introduction: Partial thickness rotator cuff tears (PTRCTs) are common, with an incidence between 17% and 37%, and a high prevalence in throwing athletes. Different surgical procedures are suggested when partial tears involve the articular portion of the rotator cuff, including arthroscopic debridement of the tear, debridement with acromioplasty, tear completion and repair, and lately transtendon repair. This systematic review describes the transtendon repair and examines indications, contraindications, complications and clinical outcome...
September 1, 2017: British Medical Bulletin
https://www.readbyqxmd.com/read/28905242/poly-n-acetyl-glucosamine-snag-enhances-early-rotator-cuff-tendon-healing-in-a-rat-model
#3
C A Nuss, J Huegel, J F Boorman-Padgett, D S Choi, S N Weiss, J Vournakis, L J Soslowsky
Rotator cuff injuries frequently require surgical repairs which have a high failure rate. Biological augmentation has been utilized in an attempt to improve tendon repair. Poly-N-acetyl glucosamine (sNAG) polymer containing nanofibers has been shown to increase the rate for healing of venous leg ulcers. The purpose of this study was to investigate the healing and analgesic properties of sNAG in a rat rotator cuff injury and repair model. 144 adult male Sprague-Dawley rats underwent a transection and repair of their left supraspinatus tendons...
September 13, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28904952/internal-impingement-of-the-shoulder-a-risk-of-false-positive-test-outcomes-in-external-impingement-tests
#4
Tim Leschinger, Christopher Wallraff, Dirk Müller, Matthias Hackenbroch, Henning Bovenschulte, Jan Siewe
BACKGROUND: External impingement tests are considered as being particularly reliable for identifying subacromial and coracoid shoulder impingement mechanisms. The purpose of the present study was to evaluate if these tests are likely to provoke an internal shoulder impingement mechanism which, in cases of a pathologic condition, can lead to a positive test result. METHOD: In 37 subjects, the mechanical contact between the glenoid rim and the rotator cuff (RC) was measured quantitatively and qualitatively in external impingement test positions using an open MRI system...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28902861/epigenetic-regulation-of-metalloproteinases-and-their-inhibitors-in-rotator-cuff-tears
#5
Mariana Ferreira Leal, Leonardo Caires Dos Santos, Adrielle Martins de Oliveira, Paulo Santoro Belangero, Eduardo Antônio Figueiredo, Carina Cohen, Felipe de Seixas Alves, Wânia Hiromi Yanaguizawa, Carlos Vicente Andreoli, Alberto de Castro Pochini, Benno Ejnisman, Marília Cardoso Smith, Maria Teresa de Seixas Alves, Moises Cohen
Rotator cuff tear is a common orthopedic condition. Metalloproteinases (MMP) and their inhibitors (TIMP) seem to play a role in the development of joint injuries and in the failure of tissue healing. However, the mechanisms of regulation of gene expression in tendons are still unknown. Epigenetic mechanisms, such as DNA methylation and microRNAs regulation, are involved in the dynamic control of gene expression. Here, the mRNA expression and DNA methylation status of MMPs (MMP1, MMP2, MMP3, MMP9, MMP13, and MMP14) and TIMPs (TIMP1-3) and the expression of miR-29 family members in ruptured supraspinatus tendons were compared with non-injured tendons of individuals without this lesion...
2017: PloS One
https://www.readbyqxmd.com/read/28899384/systematic-review-of-quantitative-imaging-biomarkers-for-neck-and-shoulder-musculoskeletal-disorders
#6
Judith E Gold, David M Hallman, Fredrik Hellström, Martin Björklund, Albert G Crenshaw, Svend Erik Mathiassen, Mary F Barbe, Sayed Ali
BACKGROUND: This study systematically summarizes quantitative imaging biomarker research in non-traumatic neck and shoulder musculoskeletal disorders (MSDs). There were two research questions: 1) Are there quantitative imaging biomarkers associated with the presence of neck and shoulder MSDs?, 2) Are there quantitative imaging biomarkers associated with the severity of neck and shoulder MSDs? METHODS: PubMed and SCOPUS were used for the literature search. One hundred and twenty-five studies met primary inclusion criteria...
September 12, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28893546/cost-effectiveness-of-magnetic-resonance-imaging-versus-ultrasound-for-the-detection-of-symptomatic-full-thickness-supraspinatus-tendon-tears
#7
Soterios Gyftopoulos, Kip E Guja, Naveen Subhas, Mandeep S Virk, Heather T Gold
BACKGROUND: The purpose of this study was to determine the value of magnetic resonance imaging (MRI) and ultrasound-based imaging strategies in the evaluation of a hypothetical population with a symptomatic full-thickness supraspinatus tendon (FTST) tear using formal cost-effectiveness analysis. METHODS: A decision analytic model from the health care system perspective for 60-year-old patients with symptoms secondary to a suspected FTST tear was used to evaluate the incremental cost-effectiveness of 3 imaging strategies during a 2-year time horizon: MRI, ultrasound, and ultrasound followed by MRI...
September 8, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28893394/biceps-tenotomy-in-the-presence-of-a-supraspinatus-tear-alters-the-adjacent-intact-tendons-and-glenoid-cartilage
#8
Zakary M Beach, Jennica J Tucker, Stephen J Thomas, Katherine E Reuther, Chancellor F Gray, Chang-Soo Lee, David L Glaser, Louis J Soslowsky
A rotator cuff tear is a common injury in athletes and workers who repeatedly perform overhead movements, and it is not uncommon for this demographic to return to activity shortly after treatment. A biceps tenotomy is often performed in the presence of a rotator cuff tear to help reduce pain and improve joint function. However, the effect of this procedure on the surrounding tissues in the glenohumeral joint is unknown. Therefore, the purpose of this study was to investigate the effect of a biceps tenotomy in the presence of a supraspinatus rotator cuff tear followed by overuse activity on ambulatory function and mechanical and histologic properties of the remaining rotator cuff tendons and glenoid cartilage...
August 26, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28879051/targeting-danger-molecules-in-tendinopathy-the-hmgb1-tlr4-axis
#9
Moeed Akbar, Derek S Gilchrist, Susan M Kitson, Briana Nelis, Lindsay A N Crowe, Emma Garcia-Melchor, James H Reilly, Shauna C Kerr, George A C Murrell, Iain B McInnes, Neal L Millar
OBJECTIVES: To seek evidence of the danger molecule, high-mobility group protein B1 (HMGB1) expression in human tendinopathy and thereafter, to explore mechanisms where HMGB1 may regulate inflammatory mediators and matrix regulation in human tendinopathy. METHODS: Torn supraspinatus tendon (established pathology) and matched intact subscapularis tendon (representing 'early pathology') biopsies were collected from patients undergoing arthroscopic shoulder surgery...
2017: RMD Open
https://www.readbyqxmd.com/read/28878470/reliability-of-musculoskeletal-ultrasound-imaging-to-measure-supraspinatus-tendon-thickness-in-healthy-subjects
#10
Ashfaq Ahmad, Mohammad A Mohseni Bandpei, S Amir Gilani, Arooj Munawar, Ishaq Ahmed, Fahad Tanveer
[Purpose] The purpose of this study was to assess intra-rater and inter-rater reliability of musculoskeletal ultrasound (MSKUS) as a tool to measure supraspinatus tendon thickness in healthy subjects. [Subjects and Methods] Twenty healthy subjects were assessed in similar sitting position. Two experienced musculoskeletal ultrasound specialists measured supraspinatus tendon thickness. Tendon was measured twice in one day by each of two raters with an interval of one hour for within day reliability and was re-measured following one week for between days reliability...
August 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28872465/increased-reliability-of-quantitative-ultrasound-measures-of-the-supraspinatus-tendon-using-multiple-image-analysts-and-analysis-runs
#11
Elizabeth R Felix, Rachel E Cowan, Tyler S Clark, Diana D Cardenas, Robert W Irwin
Quantitative ultrasound (QUS) is an inexpensive and promising tool for sensitive measurement of tendon pathology. However, few studies have reported the psychometric properties of measurements obtained using this technique for assessments of the supraspinatus tendon. The present study was undertaken to determine the variance contributed by several sources of error (participant, ultrasound operator, image analyst, analysis session) to QUS measures of the supraspinatus tendon. Transverse images of the supraspinatus tendon were captured from eleven subjects (22 shoulders) by two ultrasonographers, and each image was analyzed by two image analysts who each completed two analysis runs...
September 1, 2017: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/28869071/role-of-transplanted-bone-marrow-cells-in-development-of-rotator-cuff-muscle-fatty-degeneration-in-mice
#12
Lawrence V Klomps, Naseem Zomorodi, H Mike Kim
BACKGROUND: Rotator cuff muscle fatty degeneration after a chronic tendon tear is an irreversible pathologic change associated with poor clinical outcomes of tendon repair, and its exact pathogenesis remains unknown. We sought to investigate the role of transplanted bone marrow cells in the development of fatty degeneration, specifically in adipocyte accumulation, using a mouse model. METHODS: Fourteen mice were divided into 2 bone marrow chimeric animal groups: bone marrow transplantation (BMT) group and reverse BMT group...
August 28, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28865966/characterizing-the-macro-and-micro-mechanical-properties-of-scaffolds-for-rotator-cuff-repair
#13
Richard D J Smith, Nasim Zargar, Cameron P Brown, Navraj S Nagra, Stephanie G Dakin, Sarah J B Snelling, Osnat Hakimi, Andrew Carr
BACKGROUND: Retearing after rotator cuff surgery is a major clinical problem. Numerous scaffolds are being used to try to reduce retear rates. However, few have demonstrated clinical efficacy. We hypothesize that this lack of efficacy is due to insufficient mechanical properties. Therefore, we compared the macro and nano/micro mechanical properties of 7 commercially available scaffolds to those of the human supraspinatus tendons, whose function they seek to restore. METHODS: The clinically approved scaffolds tested were X-Repair, LARS ligament, Poly-Tape, BioFiber, GraftJacket, Permacol, and Conexa...
August 30, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28865049/exercise-therapy-for-treatment-of-supraspinatus-tears-does-not-alter-glenohumeral-kinematics-during-internal-external-rotation-with-the-arm-at-the-side
#14
Gerald A Ferrer, R Matthew Miller, Jason P Zlotnicki, Scott Tashman, James J Irrgang, Volker Musahl, Richard E Debski
PURPOSE: Rotator cuff tears are a significant clinical problem, with exercise therapy being a common treatment option for patients. Failure rates of exercise therapy may be due to the failure to improve glenohumeral kinematics. Tears involving the supraspinatus may result in altered glenohumeral kinematics and joint instability for internal/external rotation with the arm at the side because not all muscles used to stabilize the glenohumeral joint are functioning normally. The objective of the study is to assess in vivo glenohumeral kinematic changes for internal/external rotation motions with the arm at the side of patients with a symptomatic full-thickness supraspinatus tear before and after a 12-week exercise therapy programme...
September 1, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28856018/sonographic-detection-of-inferior-subluxation-in-post-stroke-hemiplegic-shoulders
#15
Bukunmi M Idowu, Oluwagbemiga O Ayoola, Victor A Adetiloye, Morenikeji A Komolafe, Babalola I Afolabi
AIM OF THE STUDY: To evaluate the usefulness of ultrasonographic acromion-greater tuberosity distance measurement and Shoulder ratio in detecting post-stroke inferior shoulder subluxation. MATERIAL AND METHODS: Forty-five hemiplegic stroke patients and 45 controls underwent shoulder sonography to measure their acromion-greater tuberosity distance. Side-to-side acromion-greater tuberosity distance differences and Shoulder ratios were derived from the acromion-greater tuberosity distance values...
June 2017: Journal of Ultrasonography
https://www.readbyqxmd.com/read/28853127/winging-of-the-scapula-diagnosed-as-parsonage-turner-syndrome-a-case-report
#16
Christine Carroll, Bill Bass
A 24-year-old active duty female Soldier complained of right shoulder burning, stinging, electrical shock-like pain with radiation to the right hand after completing a ruck march. She also complained of swelling and feelings of her cold right hand. Examination showed a deficit in the deltoid, upper trapezius, supraspinatus, and also right winging of the scapula. She also exhibited weakness to right arm, weak right hand grip, and decreased sensation over the dorsal right hand. The right hand was also noticed to be colder to touch than the left one...
July 2017: U.S. Army Medical Department Journal
https://www.readbyqxmd.com/read/28852340/thickness-of-the-rotator-cuff-tendons-at-the-articular-margin-an-anatomic-cadaveric-study
#17
William C Sessions, Rebekah L Lawrence, J Tyler Steubs, Paula M Ludewig, Jonathan P Braman
BACKGROUND: With a substantial portion of the population experiencing rotator cuff pathology, the importance of understanding mechanisms of rotator cuff disease remains critical. Current research aimed at understanding relationships between shoulder movement and cuff injuries has been hindered by our limited knowledge of the thickness of soft tissue structures within the shoulder. Therefore, the purpose of this study is to measure the thicknesses of all four rotator cuff tendons at the articular margin...
2017: Iowa Orthopaedic Journal
https://www.readbyqxmd.com/read/28851983/new-insights-into-tenocyte-immune-cell-interplay-in-an-in-vitro-model-of-inflammation
#18
Meaghan Stolk, Franka Klatte-Schulz, Aysha Schmock, Susann Minkwitz, Britt Wildemann, Martina Seifert
Inflammation plays an important role in the development and resolution of tendon diseases, but underlying mechanisms are poorly understood. We therefore aimed to analyze the response of human tenocytes to inflammatory stimuli and to uncover their interplay with macrophages in vitro. Tenocytes from human ruptured supraspinatus tendons (n = 10) were treated for three days with a stimulation mixture derived from activated mononuclear cells isolated from healthy human peripheral blood. Significantly increased expression levels of selected adhesion- and human leukocyte antigen (HLA)-molecules, and enhanced interleukin (IL)-6 release were detected by flow cytometry...
August 29, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28829699/association-between-years-of-competition-and-shoulder-function-in-collegiate-swimmers
#19
Jack D Dischler, Timothy G Baumer, Evan Finkelstein, Daniel S Siegal, Michael J Bey
BACKGROUND: Shoulder injuries are common among competitive swimmers, and the progression of shoulder pathology is not well understood. The objective of this study was to assess the extent to which years of competitive swim training were associated with physical properties of the supraspinatus muscle and tendon, shoulder strength, and self-reported assessments of shoulder pain and function. HYPOTHESIS: Increasing years of competition will be associated with declining physical properties of the supraspinatus muscle/tendon and declining self-reported assessments of pain and function...
August 1, 2017: Sports Health
https://www.readbyqxmd.com/read/28822637/porcine-dermis-patch-augmentation-of-supraspinatus-tendon-repairs-a-pilot-study-assessing-tendon-integrity-and-shoulder-function-2%C3%A2-years-after-arthroscopic-repair-in-patients-aged-60%C3%A2-years-or%C3%A2-older
#20
Matthias Flury, Dominik Rickenbacher, Christian Jung, Marco M Schneider, David Endell, Laurent Audigé
PURPOSE: To investigate the 2-year postoperative clinical and subjective outcomes after arthroscopic rotator cuff repair (ARCR) with xenologous porcine dermal patch augmentation compared with ARCR alone. METHODS: Patients aged 60 years or older with a complete supraspinatus (SSP) tendon tear underwent primary ARCR with a transosseous-equivalent technique. By use of a matched-pair comparative trial design, a consecutive series of 20 patients receiving additional xenologous porcine dermal patch augmentation (patch group) was matched by tear location with 20 patients who received ARCR only (control group)...
August 16, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
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