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https://www.readbyqxmd.com/read/28214172/does-successful-rotator-cuff-repair-improve-muscle-atrophy-and-fatty-infiltration-of-the-rotator-cuff-a-retrospective-magnetic-resonance-imaging-study-performed-shortly-after-surgery-as-a-reference
#1
Noritaka Hamano, Atsushi Yamamoto, Hitoshi Shitara, Tsuyoshi Ichinose, Daisuke Shimoyama, Tsuyoshi Sasaki, Tsutomu Kobayashi, Yohei Kakuta, Toshihisa Osawa, Kenji Takagishi
BACKGROUND: Muscle atrophy and fatty infiltration in the rotator cuff muscles are often observed in patients with chronic rotator cuff tears. The recovery from these conditions has not been clarified. METHODS: Ninety-four patients were included in this study. The improvement in muscle atrophy and fatty infiltration in successfully repaired rotator cuff tears was evaluated by magnetic resonance imaging at 1 year and 2 years after surgery and was compared with muscle atrophy and fatty infiltration observed on magnetic resonance imaging at 2 weeks after surgery to discount any changes due to the medial retraction of the torn tendon...
February 15, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28197872/mr-arthrography-of-the-shoulder-evaluation-of-isotropic-3d-intermediate-weighted-fse-and-hybrid-gre-t1-weighted-sequences
#2
Giovanni Foti, Paolo Avanzi, William Mantovani, Flavia Dal Corso, Emanuele Demozzi, Claudio Zorzi, Giovanni Carbognin
PURPOSE: To compare the diagnostic accuracy of three-dimensional (3D) fast spin echo (FSE) intermediate-weighed (IW-3D) and 3D hybrid double-echo steady-state T1-weighted sequences (Hy-3D) and two-dimensional (FSE) images (2D) at shoulder MR arthrography (MRA). MATERIALS AND METHODS: Institutional review board approval was obtained and informed consent was waived for this retrospective study. From September 2011 to October 2014, 102 patients who had undergone 1...
February 15, 2017: La Radiologia Medica
https://www.readbyqxmd.com/read/28197744/efficiency-of-quantitative-echogenicity-for-investigating-supraspinatus-tendinopathy-by-the-gray-level-histogram-of-two-ultrasound-devices
#3
Jiun-Cheng Hsu, Po-Han Chen, Kuo-Chin Huang, Yao-Hung Tsai, Wei-Hsiu Hsu
PURPOSE: The gray-level histogram of ultrasound is a promising tool for scanning the hypoechogenic appearance of supraspinatus tendinopathy, and the aim of this study was to test the hypothesis that the gray-level value of the supraspinatus tendon in the painful shoulder has a lower value on B-mode images even though in different ultrasound devices. METHODS: Sixty-seven patients who had unilateral shoulder pain with rotator cuff tendinopathy underwent bilateral shoulder ultrasonography, and we compared the mean gray-level values of painful shoulders and contralateral shoulders without any pain in each patient using two ultrasound devices...
February 14, 2017: Journal of Medical Ultrasonics
https://www.readbyqxmd.com/read/28196035/perivascular-stem-cells-diminish-muscle-atrophy-following-massive-rotator-cuff-tears-in-a-small-animal-model
#4
Claire D Eliasberg, Ayelet Dar, Andrew R Jensen, Iain R Murray, Winters R Hardy, Tomasz J Kowalski, Cameron A Garagozlo, Kyle M Natsuhara, Adam Z Khan, Owen J McBride, Peter I Cha, Benjamin V Kelley, Denis Evseenko, Brian T Feeley, David R McAllister, Bruno Péault, Frank A Petrigliano
BACKGROUND: Rotator cuff tears are a common cause of shoulder pain and often necessitate operative repair. Muscle atrophy, fibrosis, and fatty infiltration can develop after rotator cuff tears, which may compromise surgical outcomes. This study investigated the regenerative potential of 2 human adipose-derived progenitor cell lineages in a murine model of massive rotator cuff tears. METHODS: Ninety immunodeficient mice were used (15 groups of 6 mice). Mice were assigned to 1 of 3 surgical procedures: sham, supraspinatus and infraspinatus tendon transection (TT), or TT and denervation via suprascapular nerve transection (TT + DN)...
February 15, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28192875/functions-of-the-subregions-of-the-supraspinatus-muscle
#5
Takuma Yuri, Yoshiki Kuwahara, Hiromi Fujii, Yoshiro Kiyoshige
The aim of this study was to investigate the functions of the six subregions of the supraspinatus muscle (SSP) determined by Kim et al. (2007) using real-time tissue elastography (RTE). Twelve young male volunteers participated. The muscular hardness of the SSP was measured at rest and with contraction of the MMT3 in internal, neutral and external rotations. The SSP was functionally divided into five groups on the basis of the RTE results. These functional areas were roughly classified into three property groups: the anterior-superficial, anterior-middle and anterior-deep subregions, which produce contractile force for abduction; the posterior-deep subregion, which produces contractile force for external rotation; and the posterior-superficial and posterior-middle subregions, which maintain tension...
February 13, 2017: Clinical Anatomy
https://www.readbyqxmd.com/read/28188359/in-vivo-analysis-of-coracoid-and-subacromial-shoulder-impingement-mechanism-during-clinical-examination
#6
Tim Leschinger, Christopher Wallraff, Dirk Müller, Matthias Hackenbroch, Henning Bovenschulte, Jan Siewe
BACKGROUND: Understanding the mechanisms of shoulder impingement created by clinical tests is crucial to accurately evaluate the condition. The objective of this study was to relate mechanisms of subacromial and coracoid impingement occurring in positions of the shoulder during clinical examination, in quantitative and qualitative terms. METHODS: A 1.0T open magnetic resonance imaging system was used in 18 female and 19 male subjects, to determine the distances between the humeral head and the acromion or coracoid, and contact with the rotator cuff (RC)...
February 11, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28162888/the-effectiveness-of-demineralized-cortical-bone-matrix-in-a-chronic-rotator-cuff-tear-model
#7
Tanujan Thangarajah, Frederick Henshaw, Anita Sanghani-Kerai, Simon M Lambert, Gordon W Blunn, Catherine J Pendegrass
BACKGROUND: The purpose of this study was to assess the effect of demineralized bone matrix (DBM) on rotator cuff tendon-bone healing. The hypothesis was that compared with a commercially available dermal matrix scaffold, DBM would result in a higher bone mineral density and regenerate a morphologically superior enthesis in a rat model of chronic rotator cuff degeneration. METHODS: Eighteen female Wistar rats underwent unilateral detachment of the supraspinatus tendon...
February 2, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28153683/supraspinatus-muscle-occupation-ratio-predicts-rotator-cuff-reparability
#8
Jeung Yeol Jeong, Pill Ku Chung, Sang Min Lee, Jae Chul Yoo
BACKGROUND: We wished to determine the correlation between supraspinatus muscle occupation ratio and reparability of rotator cuff muscles and that of each occupation ratio with 1-muscle, 2-muscle, and 3-muscle rotator cuff injury. METHODS: We evaluated 170 patients (average age, 62.3 [40-83] years) with complete (type II) or incomplete (type III) rotator cuff repair by arthroscopy. Type II repair was defined as complete repair but less optimal coverage of the entire medial-lateral footprint...
January 30, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28152242/imaging-of-the-rabbit-supraspinatus-enthesis-at-7-tesla-a-4-week-time-course-after-repair-surgery-and-effect-of-channeling
#9
Guy Trudel, Gerd Melkus, Greg O Cron, Hakim Louati, Adnan Sheikh, Peder E Z Larson, Mark Schweitzer, Peter Lapner, Hans K Uhthoff, Odette Laneuville
PURPOSE: To image the supraspinatus enthesis reformation of rabbit shoulders by magnetic resonance at 7 Tesla (T) using T2 mapping after surgical repair and to assess the effects of channeling aimed at enhancing enthesis reformation. MATERIALS AND METHODS: In 112 rabbits, the distal supraspinatus (SSP) tendon was unilaterally detached and reattached after 1 week. At the first surgery, channeling was performed at the footprint in 64 rabbits. At the second surgery, the SSP tendon of all rabbits was re-attached to the greater tuberosity...
February 2, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28149695/validation-of-ultrasonographic-muscle-thickness-measurements-as-compared-to-the-gold-standard-of-computed-tomography-in-dogs
#10
Lindsey E Bullen, Maria G Evola, Emily H Griffith, Gabriela S Seiler, Korinn E Saker
OBJECTIVE: The objective was to quantitatively evaluate the validity of ultrasonographic (US) muscle measurements as compared to the gold standard of computed tomography (CT) in the canine. DESIGN: This was a prospective study. POPULATION: Twenty-five, client-owned dogs scheduled for CT as part of a diagnostic work-up for the management of their primary disease process were included. MATERIALS AND METHODS: Specific appendicular (cubital flexors and extensors, coxofemoral flexors and extensors) and axial (temporalis, supraspinatus, infraspinatus, lumbar epaxials) muscle groups were selected for quantitative measure based on CT planning and patient position...
2017: PeerJ
https://www.readbyqxmd.com/read/28141953/interposition-dermal-matrix-xenografts
#11
Julie A Neumann, Miltiadis H Zgonis, Kathleen D Rickert, Kendall E Bradley, Thomas J Kremen, Blake R Boggess, Alison P Toth
BACKGROUND: Management of massive rotator cuff tears in shoulders without glenohumeral arthritis remains problematic for surgeons. Repairs of massive rotator cuff tears have failure rates of 20% to 94% at 1 to 2 years postoperatively as demonstrated with arthrography, ultrasound, and magnetic resonance imaging. Additionally, inconsistent outcomes have been reported with debridement alone of massive rotator cuff tears, and limitations have been seen with other current methods of operative intervention, including arthroplasty and tendon transfers...
January 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28131694/neer-award-2016-reduced-muscle-degeneration-and-decreased-fatty-infiltration-after-rotator-cuff-tear-in-a-poly-adp-ribose-polymerase-1-parp-1-knock-out-mouse-model
#12
Michael B Kuenzler, Katja Nuss, Agnieszka Karol, Michael O Schär, Michael Hottiger, Sumit Raniga, David Kenkel, Brigitte von Rechenberg, Matthias A Zumstein
BACKGROUND: Disturbed muscular architecture, atrophy, and fatty infiltration remain irreversible in chronic rotator cuff tears even after repair. Poly (adenosine 5'-diphosphate-ribose) polymerase 1 (PARP-1) is a key regulator of inflammation, apoptosis, muscle atrophy, muscle regeneration, and adipocyte development. We hypothesized that the absence of PARP-1 would lead to a reduction in damage to the muscle subsequent to combined tenotomy and neurectomy in a PARP-1 knockout (KO) mouse model...
January 25, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28129897/quantifying-radiation-dose-delivered-to-individual-shoulder-muscles-during-breast-radiotherapy
#13
David B Lipps, Sean Sachdev, Jonathan B Strauss
BACKGROUND AND PURPOSE: Radiotherapy is an effective treatment for managing breast cancer, but patients may experience shoulder morbidity after completing radiotherapy. There is a knowledge gap regarding how the inclusion of the regional lymphatics in radiation treatment regimens influence the radiation dose delivered to the underlying shoulder musculature. MATERIAL AND METHODS: Five standardized radiation treatment regimens were developed from the computed tomography (CT) scans of 11 patients: tangent fields only (T), high tangent fields (HT), T+supraclavicular fossa and axillary apex with an anterior oblique beam (SCV), T+SCV+axillary nodes with an anterior oblique beam (SCV+AX), and T+SCV+AX with the nodal regions treated with a directly opposed beam configuration (DO)...
January 24, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28122639/persistent-stromal-fibroblast-activation-is-present-in-chronic-tendinopathy
#14
Stephanie G Dakin, Christopher D Buckley, Mohammad Hussein Al-Mossawi, Robert Hedley, Fernando O Martinez, Kim Wheway, Bridget Watkins, Andrew J Carr
BACKGROUND: Growing evidence supports a key role for inflammation in the onset and progression of tendinopathy. However, the effect of the inflammatory infiltrate on tendon cells is poorly understood. METHODS: We investigated stromal fibroblast activation signatures in tissues and cells from patients with tendinopathy. Diseased tendons were collected from well-phenotyped patient cohorts with supraspinatus tendinopathy before and after sub-acromial decompression treatment...
January 25, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28122541/physical-examination-tests-of-the-shoulder-a-systematic-review-and-meta-analysis-of-diagnostic-test-performance
#15
Sigmund Ø Gismervik, Jon O Drogset, Fredrik Granviken, Magne Rø, Gunnar Leivseth
BACKGROUND: Physical examination tests of the shoulder (PETS) are clinical examination maneuvers designed to aid the assessment of shoulder complaints. Despite more than 180 PETS described in the literature, evidence of their validity and usefulness in diagnosing the shoulder is questioned. METHODS: This meta-analysis aims to use diagnostic odds ratio (DOR) to evaluate how much PETS shift overall probability and to rank the test performance of single PETS in order to aid the clinician's choice of which tests to use...
January 25, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28111180/computed-tomography-based-prediction-of-the-straight-antegrade-humeral-nail-s-entry-point-and-exposure-of-critical-types-truth-or-fiction
#16
Simon A Euler, Clemens Hengg, Matthias Boos, Grant J Dornan, Travis Lee Turnbull, Markus Wambacher, Franz S Kralinger, Peter J Millett, Maximilian Petri
BACKGROUND: Straight antegrade intramedullary nailing of proximal humerus fractures has shown promising clinical results. However, up to 36% of all humeri seem to be "critical types" in terms of the potential violation of the supraspinatus (SSP) tendon footprint by the nail's insertion zone. The aims of this study were to evaluate if a computed tomography (CT) scan could reliably predict the nail's entry point on the humeral head and if it would be possible to preoperatively estimate the individual risk of iatrogenic violation of the SSP tendon footprint by evaluating the uninjured contralateral humerus...
January 19, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28110933/shear-wave-elastography-of-the-supraspinatus-muscle-and-tendon-repeatability-and-preliminary-findings
#17
Timothy G Baumer, Leah Davis, Jack Dischler, Daniel S Siegal, Marnix van Holsbeeck, Vasilios Moutzouros, Michael J Bey
Shear wave elastography (SWE) is a promising tool for estimating musculoskeletal tissue properties, but few studies have rigorously assessed its repeatability and sources of error. The objectives of this study were to assess: (1) the extent to which probe positioning error and human user error influence measurement accuracy, (2) intra-user, inter-user, and day-to-day repeatability, and (3) the extent to which active and passive conditions affect shear wave speed (SWS) repeatability. Probe positioning and human usage errors were assessed by acquiring SWE images from custom ultrasound phantoms...
January 18, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28108482/inhibition-of-prolyl-4-hydroxylase-decreases-muscle-fibrosis-following-chronic-rotator-cuff-tear
#18
J P Gumucio, M D Flood, A Bedi, H F Kramer, A J Russell, C L Mendias
OBJECTIVES: Rotator cuff tears are among the most frequent upper extremity injuries. Current treatment strategies do not address the poor quality of the muscle and tendon following chronic rotator cuff tears. Hypoxia-inducible factor-1 alpha (HIF-1α) is a transcription factor that activates many genes that are important in skeletal muscle regeneration. HIF-1α is inhibited under normal physiological conditions by the HIF prolyl 4-hydroxylases (PHDs). In this study, we used a pharmacological PHD inhibitor, GSK1120360A, to enhance the activity of HIF-1α following the repair of a chronic cuff tear, and measured muscle fibre contractility, fibrosis, gene expression, and enthesis mechanics...
January 2017: Bone & Joint Research
https://www.readbyqxmd.com/read/28098497/magnetic-resonance-arthrography-results-that-indicate-surgical-treatment-for-partial-articular-sided-supraspinatus-tendon-avulsion-a-retrospective-study-in-a-tertiary-center
#19
Seok Hahn, Young Han Lee, Yong-Min Chun, Eun Hae Park, Jin-Suck Suh
Background Specific findings on magnetic resonance arthrography (MRA) that indicate the need for surgery in patients with partial articular-sided supraspinatus tendon avulsion (PASTA) are not well understood. Purpose To determine which MRA findings are characteristic of patients who undergo surgery for PASTA. Material and Methods From July 2011 to February 2014, MRA findings for patients treated for PASTA were retrospectively reviewed. The patients were divided into two groups: conservative treatment and surgical repair...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28094420/evaluation-of-the-optimal-plate-position-for-the-fixation-of-supraglenoid-tubercle-fractures-in-warmbloods
#20
Sina Frei, Hans Geyer, Seamus Hoey, Anton E Fuerst, Andrea S Bischofberger
OBJECTIVES: To determine scapular cortex thickness, distal scapular bone density and describe the exact suprascapular nerve course to evaluate the best plate position for the fixation of supraglenoid tubercle fractures in horses. METHODS: Twelve equine cadaveric shoulders were examined with computed tomography. Computed tomography morphometry and density measurements (Hounsfield units [HU]) of the scapula were recorded. Statistical comparisons were made between the cranial and caudal aspects of the scapula...
January 17, 2017: Veterinary and Comparative Orthopaedics and Traumatology: V.C.O.T
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