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https://www.readbyqxmd.com/read/28719406/toward-a-biopsychosocial-ecology-of-the-human-microbiome-brain-gut-axis-and-health
#1
Karl J Maier, Mustafa al'Absi
OBJECTIVE: Rapidly expanding insights to the human microbiome and health suggest that Western medicine is poised for significant evolution, or perhaps revolution - this while the field continues on a trajectory from reductionism to a biopsychosocial (BPS) paradigm recognizing biological, psychological, and social influences on health. The apparent sensitivity of the microbiota to perturbations across BPS domains suggests that a broad and inclusive framework is needed to develop applicable knowledge in this area...
July 18, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28719374/physical-and-chemical-stability-of-budesonide-mucoadhesive-oral-suspensions-mucolox
#2
Kendice Ip, Maria Carvalho, Ashley Shan, Daniel Banov
Budesonide is a corticosteroid that has been shown effective in the treatment of eosinophilic esophagitis, but there are currently no commercial medicines to treat this chronic allergic/immune condition, despite its prevalence in the U.S. Therefore, pharmaceutical compounding is the alternative choice to meet the therapeutic need of eosinophilic esophagitis patients. Two budesonide mucoadhesive oral suspensions (1 mg/10 mL and 2 mg/10 mL) were developed using the compounding vehicle MucoLox, a proprietary mucoadhesive polymer blend that promotes mucosal adhesion...
July 2017: International Journal of Pharmaceutical Compounding
https://www.readbyqxmd.com/read/28719249/applying-sensory-modulation-to-mental-health-inpatient-care-to-reduce-seclusion-and-restraint-a-case-control-study
#3
Charlotte Andersen, Anne Kolmos, Kjeld Andersen, Volkmar Sippel, Elsebeth Stenager
BACKGROUND: Clinical training in managing conflicts and preventing violence seldom contains sensory modulation (SM) as a method to de-escalate and prevent restraint and seclusion. Sensory-based interventions promote adaptive regulation of arousal and emotion. SM is a complementary approach that is associated with reduced rates of seclusion and restraint in mental healthcare, but there is need for more research in this area. AIMS: Using SM to reduce restraint and seclusion in inpatient mental health care...
July 18, 2017: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/28717565/twenty-five-years-of-optical-coherence-tomography-the-paradigm-shift-in-sensitivity-and-speed-provided-by-fourier-domain-oct-invited
#4
Johannes F de Boer, Rainer Leitgeb, Maciej Wojtkowski
Optical coherence tomography (OCT) has become one of the most successful optical technologies implemented in medicine and clinical practice mostly due to the possibility of non-invasive and non-contact imaging by detecting back-scattered light. OCT has gone through a tremendous development over the past 25 years. From its initial inception in 1991 [Science254, 1178 (1991)] it has become an indispensable medical imaging technology in ophthalmology. Also in fields like cardiology and gastro-enterology the technology is envisioned to become a standard of care...
July 1, 2017: Biomedical Optics Express
https://www.readbyqxmd.com/read/28715306/a-data-rich-longitudinal-wellness-study-for-the-digital-age-fixing-a-broken-medical-system-requires-data-about-each-patient
#5
Gustavo Glusman
We live in an age of plentiful information, collected continuously by pervasive gadgetry, distributed through digital and social networks, and mined deeply by ever-more-powerful analytics systems. And yet, one of the things we know the least about is our bodies. When it comes to our own health, we are driving blindly. Modern medicine has clearly been remarkably successful, as evidenced by continually growing life expectancies. For example, the number of people 65 and older in the United States has seen a steady increase over the last century, rising from 3...
July 2017: IEEE Pulse
https://www.readbyqxmd.com/read/28714763/effects-of-trial-duration-on-intrasession-reliability-of-single-leg-balance-testing-on-stable-and-unstable-surfaces
#6
Bryan I Riemann, Kelsey Piersol, George J Davies
CONTEXT: Single leg balance testing is a commonly used tool in sports medicine; however, there has been no consensus on trial duration needed to obtain reliable measures. OBJECTIVE: This investigation sought to determine the minimum trial duration required to obtain the highest intrasession single and average trial reliability for single leg balance testing on stable and unstable surfaces using dominant and nondominant limbs. DESIGN: Intrasession reliability...
July 17, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/28714659/are-patients-referred-to-rehabilitation-diagnosed-accurately
#7
Piotr Tederko, Marek Krasuski, Izabella Nyka, Jerzy Mycielski, Beata Tarnacka
BACKGROUND: An accurate diagnosis of the leading health condition and comorbidities is a prerequisite for safe and effective rehabilitation. The problem of diagnostic errors in physical and rehabilitation medicine (PRM) has not been addressed sufficiently. The responsibility of a referring physician is to determine indications and contraindications for rehabilitation. AIM: To assess the rate of and risk factors for inaccurate referral diagnoses (RD) in patients referred to a rehabilitation facility...
July 17, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28714120/partial-fourier-techniques-in-single-shot-cross-term-spatiotemporal-encoded-mri
#8
Zhiyong Zhang, Lucio Frydman
PURPOSE: Cross-term spatiotemporal encoding (xSPEN) is a single-shot approach with exceptional immunity to field heterogeneities, the images of which faithfully deliver 2D spatial distributions without requiring a priori information or using postacquisition corrections. xSPEN, however, suffers from signal-to-noise ratio penalties due to its non-Fourier nature and due to diffusion losses-especially when seeking high resolution. This study explores partial Fourier transform approaches that, acting along either the readout or the spatiotemporally encoded dimensions, reduce these penalties...
July 16, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28713470/differences-in-anthropometry-biological-age-and-physical-fitness-between-young-elite-kayakers-and-canoeists
#9
Daniel López-Plaza, Fernando Alacid, José María Muyor, Pedro Ángel López-Miñarro
The aim of this study was to determine the anthropometric and physical characteristics of youth elite paddlers and to identify the differences between kayakers and canoeists. A total of 171 male paddlers (eighty-nine kayakers and eighty-two canoeists), aged 13.69 ± 0.57 years (mean ± SD) volunteered to participate in this study. The participants completed basic anthropometric assessments (body mass, stretch stature, sitting height, body mass index, maturity level, sum of 6 skinfolds and fat mass percentage) as well as a battery of physical fitness tests (overhead medicine ball throw, counter movement jump, sit-and-reach and 20 m multi-stage shuttle run tests)...
June 2017: Journal of Human Kinetics
https://www.readbyqxmd.com/read/28713440/investigating-the-physical-stability-of-repackaged-medicines-stored-into-commercially-available-multicompartment-compliance-aids-mcas
#10
Bahijja Tolulope Raimi-Abraham, Alba Garcia Del Valle, Carlota Varon Galcera, Susan Anne Barker, Mine Orlu
BACKGROUND: Compliance aids are devices which have been developed and are currently used to assist individuals in their medicines management. The use of compliance aids involves the transfer of medicines from the manufacturers' original packaging and repackaged into an multicompartment compliance aid (MCA). MCAs do not guarantee the same level of protection compared to manufacturer's original packaging. OBJECTIVE: The aim of this study was to investigate the stability profile of atenolol, aspirin and lansoprazole dosage forms repackaged together in two different commercially available MCAs...
June 2017: Journal of Pharmaceutical Health Services Research
https://www.readbyqxmd.com/read/28713078/-the-influence-of-pain-aliments-and-vertebral-mobility-in-patients-after-whole-body-cryotherapy
#11
Zbigniew Śliwiński, Beata Michalak, Jarosław Pasek, Grzegorz Śliwiński, Sebastian Szajkowski, Aleksander Sieroń
INTRODUCTION: The motive efficiency depends from many factors, in this currently also form the state of health. The change in grounds of vertebral column causing the limitations of mobility and pain can significance worsen the functional state, motive efficiency and quality of patient's life. The leadership of active mode of life complying to recommendations the preventive style of life as well as the using with interventions of physical medicine influences on improvement significance the state of health...
2017: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/28712924/advanced-methodologies-for-cocrystal-synthesis
#12
Dennis Douroumis, Steven A Ross, Ali Nokhodchi
Pharmaceutical cocrystals are multicomponent systems composed of two or more molecules and held together by H-bonding. Currently, cocrystals provide exciting opportunities in the pharmaceutical industry for the development and manufacturing of new medicines by improving poor physical properties of Active Pharmaceutical Ingredients (APIs) such as processability, solubility, stability and bioavailability. According to the recent reclassification, cocrystals are considered as drug polymorph rather a new API which has a significant impact on drug development, regulatory submissions and intellectual property protection...
July 13, 2017: Advanced Drug Delivery Reviews
https://www.readbyqxmd.com/read/28711232/sleep-an-underemphasized-aspect-of-health-and-development-in-neurorehabilitation
#13
Olaf Verschuren, Jan Willem Gorter, Lesley Pritchard-Wiart
Sleep deficiency has unique causes and implications for children with neonatal brain injury; contributing to the development or exacerbation of neurodevelopmental impairments and yet it is an underemphasized aspect of health and development. There is very little research evidence to guide the management of sleep disorders in children with cerebral palsy, a common neurodevelopmental disability of childhood. This paper is a comprehensive review and analysis of the literature regarding what is known about sleep quantity and quality in children with cerebral palsy...
July 12, 2017: Early Human Development
https://www.readbyqxmd.com/read/28710228/longitudinal-qualitative-study-describing-family-physicians-experiences-with-attempting-to-integrate-physical-activity-prescriptions-in-their-practice-it-s-not-easy-to-change-habits
#14
Mathieu Bélanger, Emily Wolfe Phillips, Connor O'Rielly, Bertin Mallet, Shane Aubé, Marylène Doucet, Jonathan Couturier, Maxime Mallet, Jessica Martin, Christine Gaudet, Nathalie Murphy, Jennifer Brunet
OBJECTIVE: Physical activity (PA) prescriptions provided by family physicians can promote PA participation among patients, but few physicians regularly write PA prescriptions. The objective of this study was to describe family physicians' experiences of trying to implement written PA prescriptions into their practice. DESIGN: Longitudinal qualitative study where participants were interviewed four times during a 12-month period. After the first interview, they were provided with PA prescription pads...
July 13, 2017: BMJ Open
https://www.readbyqxmd.com/read/28709862/1st-european-congress-of-medical-physics-september-1-4-2016-medical-physics-innovation-and-vision-within-europe-and-beyond
#15
EDITORIAL
Virginia Tsapaki, George C Kagadis, Marco Brambilla, Mario Ciocca, Catharine H Clark, Harry Delis, Giovanni Mettivier
Medical Physics is the scientific healthcare profession concerned with the application of the concepts and methods of physics in medicine. The European Federation of Organisations for Medical Physics (EFOMP) acts as the umbrella organization for European Medical Physics societies. Due to the rapid advancements in related scientific fields, medical physicists must have continuous education through workshops, training courses, conferences, and congresses during their professional life. The latest developments related to this increasingly significant medical speciality were presented during the 1st European Congress of Medical Physics 2016, held in Athens, September 1-4, 2016, organized by EFOMP, hosted by the Hellenic Association of Medical Physicists (HAMP), and summarized in the current volume...
July 11, 2017: Physica Medica: PM
https://www.readbyqxmd.com/read/28709077/phytonanotherapy-for-management-of-diabetes-using-green-synthesis-nanoparticles
#16
K Anand, C Tiloke, Pragalathan Naidoo, A A Chuturgoon
The world has a rich diversity of indigenous medicinal plants. The World Health Organization (WHO) gives high priority to eco-friendly, non-hazardous and cost effective healthcare such as the use of medicinal plants to treat various illnesses, including Human immunodeficiency virus (HIV) infection and Acquired immune deficiency syndrome (AIDS), tuberculosis (TB), diabetes mellitus (DM), malaria, and cancer. In developing countries, a high proportion of the population tends to use complementary and alternative medicines (CAM) together with conventional prescription drugs...
June 27, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28709048/intentional-burn-injury-assessment-of-allegations-of-self-infliction
#17
Juliet Cohen, Jo Pettitt, Emily Wilbourn
This study investigates the question of whether there is evidence that suggests the possibility of self-infliction, or self-infliction by proxy, of burn injury among a group of asylum claimants in the UK who have attributed such injuries to torture, and how such evidence might be assessed. The question arose from the observations of doctors at the UK-based charity Freedom from Torture that increasing numbers of individuals from Sri Lanka who described a history of torture had suffered severe and disfiguring burn injuries from heated metal objects, and the suggestion from asylum decision-makers that in some cases such injuries could have been acquired deliberately by self-infliction or self-infliction by proxy rather than by torture as claimed...
July 5, 2017: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/28708990/electroporation-by-concentric-type-needle-electrodes-and-arrays
#18
Yi Kung, Alexey Lihachev, Saulius Šatkauskas, Keng-Li Lan, Wen-Shiang Chen
The efficacy of genomic medicine depends on gene transfer efficiency. In this area, electroporation has been found to be a highly promising method for physical gene transfer. However, electroporation raises issues related to electrical safety, tissue damage, and the number of required wounds. Concentric-type needle electrodes seek to address these issues by using a lower bias (10V), a single wound, fewer processing steps, and a smaller working area (≈10mm(3)), thus offering greater accuracy and precision...
July 8, 2017: Bioelectrochemistry
https://www.readbyqxmd.com/read/28707583/cannabis-an-overview-of-its-adverse-acute-and-chronic-effects-and-their-implications
#19
Talitha C Ford, Amie C Hayley, Luke A Downey, Andrew C Parrott
In many communities, cannabis is perceived as a low-risk drug, leading to political lobbying to decriminalise its use. However, acute and chronic cannabis use has been shown to be harmful to several aspects of psychological and physical health, such as mood states, psychiatric outcomes, neurocognition, driving and general health. Furthermore, cannabis is highly addictive, and the adverse effects of withdrawal can lead to regular use. These in turn have adverse implications for public safety and health expenditure...
July 12, 2017: Current Drug Abuse Reviews
https://www.readbyqxmd.com/read/28704193/rehabilitation-of-patients-with-hip-joint-arthroplasty-late-post-surgery-period-hospital-rehabilitation
#20
Maya S Krastanova, Elena M Ilieva, Danelina E Vacheva
BACKGROUND: Hip joint replacement (endoprosthesis, alloplasty) has become one of the most frequent surgery interventions of the 20th century. AIM: To conduct rehabilitation therapy in the late post-surgery period of hospital rehabilitation (45 days after surgery), to track patients' progress and measure the results. MATERIALS AND METHODS: One hundred and fifty-two patients with hip joint endoprosthesis were included in the study. All underwent surgery and rehabilitation at the Department of Clinical Rehabilitation of the Physical and Rehabilitation Medicine Clinic at Doctor G...
June 1, 2017: Folia Medica
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