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https://www.readbyqxmd.com/read/28530492/3d-printing-in-liver-surgery-a-systematic-review
#1
Jan Sylwester Witowski, Jasamine Coles-Black, Tomasz Zbigniew Zuzak, Michał Pędziwiatr, Jason Chuen, Piotr Major, Andrzej Budzyński
BACKGROUND: Rapid growth of three-dimensional (3D) printing in recent years has led to new applications of this technology across all medical fields. This review article presents a broad range of examples on how 3D printing is facilitating liver surgery, including models for preoperative planning, education, and simulation. MATERIALS AND METHODS: We have performed an extensive search of the medical databases Ovid/MEDLINE and PubMed/EMBASE and screened articles fitting the scope of review, following previously established exclusion criteria...
May 22, 2017: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/28530385/polymeric-3d-printed-functional-microcantilevers-for-biosensing-applications
#2
Stefano Stassi, Erika Fantino, Roberta Calmo, Annalisa Chiappone, Matteo Gillono, Davide Scaiola, Candido Fabrizio Pirri, Carlo Ricciardi, Alessandro Chiado', Ignazio Roppolo
The present work shows for the first time the production of mass sensitive polymeric biosensors by 3D printing technology with intrinsic functionalities. We demonstrate the feasibility of mass sensitive biosensors in the form of microcantilever in a one-step printing process, using acrylic acid as functional co-monomer for introducing a controlled amount of functional groups that can covalently immobilize the biomolecules onto the polymer. The effectiveness of the application of 3D printed microcantilevers as biosensors is then demonstrated with their implementation in a standard immunoassay protocol...
May 22, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28530209/reproducible-3d-printed-head-tanks-for-electrical-impedance-tomography-with-realistic-shape-and-conductivity-distribution
#3
James Avery, Kirill Aristovich, Barney Low, David Holder
OBJECTIVE: Electrical impedance tomography (EIT) has many promising applications in brain injury monitoring. To evaluate both instrumentation and reconstruction algorithms, experiments are first performed in head tanks. Existing methods, whilst accurate, produce a discontinuous conductivity, and are often made by hand, making it hard for other researchers to replicate. APPROACH: We have developed a method for constructing head tanks directly in a 3D printer. Conductivity was controlled through perforations in the skull surface, which allow for saline to pass through...
May 22, 2017: Physiological Measurement
https://www.readbyqxmd.com/read/28530207/fabrication-of-biomimetic-bone-grafts-with-multi-material-3d-printing
#4
Nicholas Sears, Prachi Dhavalikar, Michael Whitely, Elizabeth Cosgriff-Hernandez
Extrusion deposition is a versatile method for the 3D printing of biomaterials such as hydrogels, ceramics, and suspensions. Recently, a new class of emulsion inks were developed that can be used to create tunable, hierarchically porous materials with a cure-on-dispense method. Propylene fumarate dimethacrylate (PFDMA) was selected to fabricate bone grafts using this technology due to its established biocompatibility, osteoconductivity, and good compressive properties. Scaffolds fabricated from PFDMA emulsion inks displayed compressive modulus and yield strength of approximately 15 and 1 MPa, respectively...
May 22, 2017: Biofabrication
https://www.readbyqxmd.com/read/28530131/a-novel-combination-of-a-polycaprolactone-fumarate-pclf-scaffold-with-polyethylene-terephthalate-pet-sutures-for-intra-articular-ligament-regeneration
#5
Joshua Parry, Eric R Wagner, Peter Kok, Mahrokh Dadsetan, Michael J Yaszemski, Andre J van Wijnen, Sanjeev Kakar
Intra-articular ligamentous injuries are typically unrepairable and have limited outcomes after graft reconstruction. A combination of porous polycaprolactone fumarate (PCLF) scaffolds with polyethylene terephthalate (PET) sutures was developed with the goal of regenerating intra-articular ligaments. Scaffolds were fabricated by injecting PCLF over 3D-printed molds containing two strands of PET suture down its central pore followed by crosslinking. Scaffolds were seeded with human mesenchymal stem cells (MSCs) from adipose tissue...
May 20, 2017: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/28530091/3d-bioprinting-of-highly-thixotropic-alginate-methylcellulose-hydrogel-with-strong-interface-bonding
#6
Huijun Li, Yu Jun Tan, Kah Fai Leong, Lin Li
A robust alginate/methylcellulose (Alg/MC) blend hydrogel, with a strategy to improve adhesion between printed layers, has been fabricated for the first time for 3D bioprinting. The optimized Alg/MC blend hydrogel exhibits highly thixotropic property, great extrudability and stackability. With treatment by a trisodium citrate (TSC) solution, the interfacial bonding between printed layers is significantly improved. The TSC solution acts as a chelating agent to remove the superficial calcium ions at each layer...
May 22, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28529664/patient-specific-3d-models-aid-planning-for-triplane-proximal-femoral-osteotomy-in-slipped-capital-femoral-epiphysis
#7
L Cherkasskiy, J P Caffrey, A F Szewczyk, E Cory, J D Bomar, C L Farnsworth, M Jeffords, D R Wenger, R L Sah, V V Upasani
PURPOSE: Slipped capital femoral epiphysis (SCFE) can result in a complex three-dimensional (3D) deformity of the proximal femur. A three-plane proximal femoral osteotomy (TPFO) has been described to improve hip mechanics. The purpose of this study was to evaluate the benefits of using 3D print technology to aid in surgical planning. PATIENTS AND METHODS: Fifteen children treated with TPFO for symptomatic proximal femoral deformity due to SCFE were included in this study...
April 2017: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/28525774/development-and-validation-of-a-physical-model-to-investigate-the-biomechanics-of-infant-head-impact
#8
M Jones, D Darwall, G Khalid, R Prabhu, A Kemp, O Arthurs, P Theobald
Head injury in childhood is the single most common cause of death or permanent disability from injury. However, despite its frequency and significance, there is little understanding of the response of a child's head to injurious loading. This is a significant limitation when making early diagnoses, informing clinical and/or forensic management or injury prevention strategies. With respect to impact vulnerability, current understanding is predominantly based on a few post-mortem-human-surrogate (PMHS) experiments...
April 13, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28524375/bioprinted-osteogenic-and-vasculogenic-patterns-for-engineering-3d-bone-tissue
#9
Batzaya Byambaa, Nasim Annabi, Kan Yue, Grissel Trujillo-de Santiago, Mario Moisés Alvarez, Weitao Jia, Mehdi Kazemzadeh-Narbat, Su Ryon Shin, Ali Tamayol, Ali Khademhosseini
Fabricating 3D large-scale bone tissue constructs with functional vasculature has been a particular challenge in engineering tissues suitable for repairing large bone defects. To address this challenge, an extrusion-based direct-writing bioprinting strategy is utilized to fabricate microstructured bone-like tissue constructs containing a perfusable vascular lumen. The bioprinted constructs are used as biomimetic in vitro matrices to co-culture human umbilical vein endothelial cells and bone marrow derived human mesenchymal stem cells in a naturally derived hydrogel...
May 19, 2017: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/28523275/online-detection-of-peroxidase-using-3d-printing-active-magnetic-mixing-and-spectra-analysis
#10
Shanshan Bai, Chengqi Gan, Gaozhe Cai, Lei Wang, Mingyong Chen, Qingan Han, Jianhan Lin
A new method for online detection of peroxidase (POD) using 3D printing, active magnetic mixing, fluidic control, and optical detection was developed and demonstrated in this study. The proposed POD detection system consisted of a 3D printing and active magnetic mixing based fluidic chip for online catalytic reaction, an optical detector with a fluidic flow cell for quantitative determination of the final catalysate, and a single-chip microcontroller based controller for automatic control of two rotating magnetic fields and four precise peristaltic pumps...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28523082/three-dimensional-printing-custom-made-implants-for-craniomaxillofacial-reconstructive-surgery
#11
REVIEW
Mariana Matias, Horácio Zenha, Horácio Costa
Craniomaxillofacial reconstructive surgery is a challenging field. First it aims to restore primary functions and second to preserve craniofacial anatomical features like symmetry and harmony. Three-dimensional (3D) printed biomodels have been widely adopted in medical fields by providing tactile feedback and a superior appreciation of visuospatial relationship between anatomical structures. Craniomaxillofacial reconstructive surgery was one of the first areas to implement 3D printing technology in their practice...
June 2017: Craniomaxillofacial Trauma & Reconstruction
https://www.readbyqxmd.com/read/28520846/patient-specific-augmentation-rhinoplasty-using-a-three-dimensional-simulation-program-and-three-dimensional-printing
#12
Yim Don Choi, Youngjun Kim, EunSoo Park
Background: The convergence of three-dimensional (3D) simulation, tissue engineering, and 3D printing technology is creating a paradigm shift in plastic surgery. In augmentation rhinoplasty, determining the ideal material and design method has been a critical issue for many years. Thus, these technologies are expected to make important contributions to augmentation rhinoplasty. Objectives: We sought to validate the feasibility of the 3D carving simulation and patient-specific implant fabrication system (3D carving system) in a clinical trial using reproducibility tests...
May 17, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/28520396/simultaneous-on-line-monitoring-of-multiple-reactions-using-a-miniature-mass-spectrometer
#13
Christopher J Pulliam, Ryan M Bain, Heather L Osswald, Dalton T Snyder, Patrick W Fedick, Stephen T Ayrton, Tawnya G Flick, R Graham Cooks
Advanced methods of chemical sampling using miniature mass spectrometer technology are applied to monitor slow reactions at a frequency of ca 180 hr-1. There is no detectable sample carryover and in-line derivatization is used in the case of poorly ionizing compounds. Moreover, we demonstrate high reproducibility with a relative error of less than 10% for major com-ponents. Monitoring is enabled using a continuous-flow nano-electrospray (CF-nESI) probe contained in a custom-built 3D-printed rotary holder. The holder position is automatically set using a stepper motor controlled by a microcontroller...
May 18, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28520334/kidney-anatomy-three-dimensional-3d-printed-pelvicalyceal-system-models-of-the-collector-system-improve-the-diagnosis-and-treatment-of-stone-disease
#14
EDITORIAL
Luciano A Favorito
No abstract text is available yet for this article.
May 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28518077/inkjet-printed-polyvinyl-alcohol-multilayers
#15
Iulia Salaoru, Zuoxin Zhou, Peter Morris, Gregory J Gibbons
Inkjet printing is a modern method for polymer processing, and in this work, we demonstrate that this technology is capable of producing polyvinyl alcohol (PVOH) multilayer structures. A polyvinyl alcohol aqueous solution was formulated. The intrinsic properties of the ink, such as surface tension, viscosity, pH, and time stability, were investigated. The PVOH-based ink was a neutral solution (pH 6.7) with a surface tension of 39.3 mN/m and a viscosity of 7.5 cP. The ink displayed pseudoplastic (non-Newtonian shear thinning) behavior at low shear rates, and overall, it demonstrated good time stability...
May 11, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28518066/scaled-anatomical-model-creation-of-biomedical-tomographic-imaging-data-and-associated-labels-for-subsequent-sub-surface-laser-engraving-ssle-of-glass-crystals
#16
Aislinn M Betts, Matthew T McGoldrick, Christopher R Dethlefs, Justin Piotrowicz, Tony Van Avermaete, Jeff Maki, Steve Gerstler, W M Leevy
Biomedical imaging modalities like computed tomography (CT) and magnetic resonance (MR) provide excellent platforms for collecting three-dimensional data sets of patient or specimen anatomy in clinical or preclinical settings. However, the use of a virtual, on-screen display limits the ability of these tomographic images to fully convey the anatomical information embedded within. One solution is to interface a biomedical imaging data set with 3D printing technology to generate a physical replica. Here we detail a complementary method to visualize tomographic imaging data with a hand-held model: Sub Surface Laser Engraving (SSLE) of crystal glass...
April 25, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28515424/a-split-ring-resonator-dielectric-probe-for-near-field-dielectric-imaging
#17
Dmitry Isakov, Chris J Stevens, Flynn Castles, Patrick S Grant
A single split-ring resonator (SRR) probe for 2D surface mapping and imaging of relative dielectric permittivity for the characterisation of composite materials has been developed. The imaging principle, the analysis and the sensitivity of the SRR surface dielectric probe data is described. The surface dielectric properties of composite materials in the frequency range 1-3 GHz have been measured based on the magnetic resonance frequency of the transmission loss of the SRR dielectric probe when in contact with the surface...
May 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28514229/an-open-source-wireless-capable-miniature-microscope-system
#18
William A Liberti, L Nathan Perkins, Daniel P Leman, Timothy J Gardner
OBJECTIVE: Fluorescence imaging through head-mounted microscopes in freely behaving animals is becoming a standard method to study neural circuit function. Flexible, open-source designs are needed to spur evolution of the method. APPROACH: We describe a miniature microscope for single-photon fluorescence imaging in freely behaving animals. The device is made from 3D printed parts and off-the-shelf components. These microscopes weigh less than 1.8 g, can be configured to image a variety of fluorophores, and can be used wirelessly or in conjunction with active commutators...
May 17, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28513855/technical-note-system-for-evaluating-local-hypothermia-as-a-radioprotector-of-the-rectum-in-a-small-animal-model
#19
Brian A Hrycushko, Chenchen Bing, Cecil Futch, Michelle Wodzak, Strahinja Stojadinovic, Paul M Medin, Rajiv Chopra
PURPOSE: The protective effects of induced or even accidental hypothermia on the human body are widespread with several medical uses currently under active research. In vitro experiments using human cell lines have shown hypothermia provides a radioprotective effect that becomes more pronounced at large, single-fraction doses common to stereotactic body radiotherapy (SBRT) and stereotactic radiosurgery (SRS) treatments. This work describes the development of a system to evaluate local hypothermia for a radioprotive effect of the rat rectum during a large dose of radiation relevant to prostate SBRT...
May 17, 2017: Medical Physics
https://www.readbyqxmd.com/read/28512850/in-situ-handheld-3d-bioprinting-for-cartilage-regeneration
#20
Claudia Di Bella, Serena Duchi, Cathal D O'Connell, Romane Blanchard, Cheryl Augustine, Zhilian Yue, Fletcher Thompson, Christopher Richards, Stephen Beirne, Carmine Onofrillo, Sebastien H Bauquier, Stewart D Ryan, Peter Pivonka, Gordon G Wallace, Peter F Choong
Articular cartilage injuries experienced at an early age can lead to the development of osteoarthritis later in life. In situ 3D printing is an exciting and innovative bio-fabrication technology that enables the surgeon to deliver tissue- engineering techniques at the time and location of need. We have created a hand- held 3D printing device (Biopen) that allows the simultaneous co-axial extrusion of bioscaffold and cultured cells directly into the cartilage defect in vivo in a single session surgery. This pilot study assesses the ability of the Biopen to repair a full thickness chondral defect and the early outcomes in cartilage regeneration, and compares these results to other treatments in a large animal model...
May 17, 2017: Journal of Tissue Engineering and Regenerative Medicine
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