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Adam R Chin, Jin Gao, Yadong Wang, Juan M Taboas, Alejandro J Almarza
PURPOSE: Biodegradable polymeric scaffolds have been used for tissue engineering approaches and can be used to regenerate temporomandibular joint (TMJ) tissues. Synthetic acellular polymeric poly(glycerol sebacate) (PGS) scaffolds and natural scaffolds made from gelatin are polymeric scaffold sponges that could provide a substrate for cell infiltration and remodeling. The authors studied the regenerative potential of these 2 scaffolds in addition to a bioactive signal, magnesium (Mg), in a novel fibrocartilage defect model in the goat mandibular condylar cartilage (MCC)...
February 22, 2018: Journal of Oral and Maxillofacial Surgery
Koichiro Ueki, Akinori Moroi, Takamitsu Tsutsui, Ryota Hiraide, Akihiro Takayama, Yuki Saito, Momoko Sato, Nana Baba, Tatsuya Tsunoda, Asami Hotta, Kunio Yoshizawa
PURPOSE: The purpose of this study was to compare time-course changes in temporomandibular joint (TMJ) space between mandibular advancement surgery and setback surgery after sagittal split ramus osteotomy (SSRO) and Le Fort I osteotomy. SUBJECTS AND METHODS: The subjects were 46 patients (92 joints) who underwent bi-maxillary surgery. The TMJ disc position was assessed by magnetic resonance imaging (MRI) and the anterior, superior, posterior, medial and lateral joint spaces were assessed by computed tomography (CT), preoperatively and at 1 week and 1 year postoperative...
February 9, 2018: Journal of Cranio-maxillo-facial Surgery
Miho Ibi, Sawa Horie, Seiko Kyakumoto, Naoyuki Chosa, Mariko Yoshida, Masaharu Kamo, Masato Ohtsuka, Akira Ishisaki
Many inflammatory cells are known to home to inflamed temporomandibular joint (TMJ) tissues by stimulation with cytokines and chemokines produced by inflammatory lesions in the TMJ. However, how the inflammatory cells affect the progression of inflammation in TMJ synovial tissues after their homing to inflamed TMJ site is still uncertain. Here, we isolated and cultured TMJ synoviocyte-like cells (TMJSCs) from murine TMJ tissues. We demonstrated that interleukin 1b (IL-1β) upregulated expression of monocyte chemoattractant protein 1 (MCP-1) in TMJSCs...
March 13, 2018: Bioscience Reports
Peter Stoustrup, Christian Kerting Iversen, Kasper Dahl Kristensen, Cory M Resnick, Carlalberta Verna, Sven Erik Nørholt, Shelly Abramowicz, Annelise Küseler, Paolo Maria Cattaneo, Troels Herlin, Thomas Klit Pedersen
INTRODUCTION: Patients with juvenile idiopathic arthritis (JIA) and involvement of the temporomandibular joint (TMJ) often experience abnormal facial growth. Three-dimensional (3D) assessment of dentofacial growth deviation has become more common with advancement and commercialization of imaging technologies. However, no standardized guidelines exist for interpretation of 3D imaging in patients with JIA. The aim of this study was to propose and validate morphometric measures for the 3D radiographic assessment of dentofacial growth deviation in patients with JIA to enhance: 1) Description of dentofacial growth deviation; 2) Treatment planning; 3) Longitudinal follow-up...
2018: PloS One
Guan Yun Frances Wang, Xiang Qun Shi, Wenjia Wu, Maria Gueorguieva, Mu Yang, Ji Zhang
Temporomandibular disorder (TMD) is a set of heterogeneous musculoskeletal conditions involving the temporomandibular joint (TMJ) and/or the masticatory muscles. Up to 33% of the population has had at least one symptom of TMD with 5-10% of them requiring treatment. Common symptoms include limited jaw movement, joint sound, and pain in the orofacial area. Once TMD becomes chronic, it can be debilitating with comorbidities that greatly reduce one's overall quality of life. However, the underlying mechanism of TMD is unclear due to the multicausative nature of the disease...
March 12, 2018: Pain
Rawand Mustafa, Metin Güngörmüş, Nur Mollaoğlu
PURPOSE: The aim of this study was to compare and evaluate the efficacy of different concentrations of dextrose prolotherapy for the treatment of temporomandibular joint (TMJ) hypermobility. PATIENTS AND METHODS: A prospective, randomized clinical trial including patients with subluxation or dislocation was performed. The study comprised 40 patients. Patients were randomly divided into 4 groups: control group, 10% dextrose, 20% dextrose, and 30% dextrose group. Patients in all groups received injections into 4 different areas of each TMJ in 4 sessions at monthly intervals...
March 12, 2018: Journal of Craniofacial Surgery
Marshall F Newman, D Graham Lee, M Kinon Lecholop
Treatment of patients with bilateral temporomandibular joint (TMJ) ankylosis in a single-stage procedure can be challenging. The implementation of intraoperative navigation has proved beneficial by enabling faster and safer excision by providing real-time identification of vital structures. Navigation also can be used to verify site preparation for custom joint prostheses. This article seeks to establish a protocol, based on the use of intermaxillary fixation screws, to produce accurate and repeatable outcomes for the correction of bilateral TMJ ankylosis with total joint replacement in a single-stage procedure...
February 20, 2018: Journal of Oral and Maxillofacial Surgery
Audrey Moreau, Mourad-Azzeddine Benassarou, Lotfi Benslama, Patrick Goudot, Thomas Schumann
INTRODUCTION: Temporomandibular joint (TMJ) disorders are a common reason for consultation. Failure of medical treatments sometimes leads to the need for one of many surgical alternatives. Our purpose was to evaluate the results of anterior pedicle temporalis muscle flap interposition in the treatment of TMJ disorders. MATERIAL AND METHODS: For this prospective study, we selected 18 patients who underwent TMJ surgery involving the interposition of a temporalis muscle flap according to a standardized technique, between January 1, 2009 and August 31, 2014...
March 9, 2018: Journal of Stomatology, Oral and Maxillofacial Surgery
Tao Ye, Dongliang Sun, Tong Mu, Yi Chu, Hui Miao, Mian Zhang, Hongxu Yang, Qian Liu, Lei Lu, Xianghui Xing, Shibin Yu
The striking predilection of temporomandibular disorders (TMD) in women, especially during gonad-intact puberty or reproductive years, indicates that oestrogen plays an important role in the progression of TMD, but the underlying mechanism remains unclear. In this study, unilateral anterior crossbite (UAC) was used to create temporomandibular joint osteoarthritis (TMJ OA) models in rats, while 17β-estradiol (E2 ) injections were applied to mimic patients with high-physiological levels of oestrogen. Micro-CT scanning, histological staining and real-time PCR assays were preformed to observe the degenerative changes in the mandibular condylar cartilage and subchondral bone...
March 9, 2018: Bone
Xinqi Huang, Xiao Cen, Jun Liu
BACKGROUND: The aim of this study was to assess the influence of protraction facemask (PFM) on temporomandibular joint (TMJ) of skeletal Class III malocclusion patients. METHOD: Literature searches were carried out electronically in five English and three Chinese databases (Cochrane Database of Systematic Reviews, the Cochrane Central Register of Controlled Trials, PubMed, Embase, MEDLINE (via Ovid), Chinese Biomedical Literature Database, China National Knowledge Infrastructure, and VIP Database)...
March 12, 2018: BMC Oral Health
Marisabel Magnifico, Diana Cassi, Mauro Gandolfini, Andrea Toffoli, Piero A Zecca, Alberto DI Blasio
BACKGROUND: Moebius syndrome is a rare condition characterized by bilateral facial and abducens nerve paralysis. The aim of this study is to evaluate the main orthodontic features and the frequency of associated clinical characteristics in patients with Moebius Syndrome (MS). METHODS: According to Terzis classifications, 58 patients with MS aged 8 months to 46 years old underwent orthodontics and clinical examination. RESULTS: Strabismus, upper and lower limb malformations, lip and palatal cleft were frequently associated with MS...
March 8, 2018: Minerva Stomatologica
Y L Rodrigues, M T Mathew, L G Mercuri, J S P da Silva, B Henriques, J C M Souza
The aim of this study was to perform a literature review on the use of finite element modeling (FEM) for the evaluation of the biomechanical behavior of temporomandibular joint replacement (TMJR) devices. An electronic search of online medical and scientific literature database was conducted using selected search terms. The search identified 307 studies, of which 19 were considered relevant to this study. Of the 19 selected studies, 10 (52.6%) investigated the influence of geometry and fixation methods, while two (10...
March 8, 2018: International Journal of Oral and Maxillofacial Surgery
Said Algan, Murat Kara, Mehmet Akif Cakmak, Onder Tan, Hakan Cinal, Ensar Zafer Barin, Akin Inaloz
OBJECTIVE: Condylar and subcondylar fractures (CSFs) are among the most common mandible fractures. If reduction of these fractures is not carried out correctly, serious complications can result, including infection, damage to temporomandibular joint (TMJ) function, malocclusion, nonunion, malunion, and ankylosis of the TMJ. METHODS: We used a preauricular, mini-incision, open technique (PMIOT) for CSF of the mandible. 66 patients (48 males, 18 females), with a total of 72 CSFs of the mandible, were repaired with PMIOT between 2011 and 2016...
February 8, 2018: Journal of Cranio-maxillo-facial Surgery
I D Davies, M Woods, I Muir-Nelson, A Messiha
Chronic recurrent temporomandibular joint (TMJ) dislocation is both an uncommon and debilitating condition of the facial skeleton. Various conservative management strategies have been tried, but these have often been associated with poor and transient outcomes. The use of a simple, innovative, and non-invasive solution is presented herein. A co-ordinated multidisciplinary approach was used in which the oral and maxillofacial laboratory technicians produced a customized headgear appliance that utilizes a 'seat belt'-like technology...
March 5, 2018: International Journal of Oral and Maxillofacial Surgery
Zhigui Ma, Haoming Zhao, Baoting Fan, Chi Yang, Minjie Chen, Shanyong Zhang
To evaluate the feasibility of the orthodontic traction after local resection of the condylar osteochondroma (OC).From November 2011 to September 2016, consecutive patients with condylar OC who underwent orthodontic extraction after local resection of the mass were reviewed. Clinical data and cone-beam computed tomography (CT) were obtained before treatment (T0), 1 week after surgery (T1), and at least 6-month follow-up after OC resection (T2). Repeated-measures analysis of variance with Bonferroni multiple-comparison test was used to compare the 3-dimensional cephalometric variables at different time points and the paired t test was used to compare changes of temporomandibular joint (TMJ) space between the 2 sides at T1 and T2...
March 2018: Medicine (Baltimore)
Aviv Ouanounou, Michael Goldberg, Daniel A Haas
Temporomandibular disorder (TMD) is a collective term that includes disorders of the temporomandibular joint (TMJ) and of the masticatory muscles and their associated structures. TMDs are characterized by pain, joint sounds and restricted mandibular movement, and drugs are widely used in the management of that pain. Pharmacological agents commonly used for the treatment of TMDs include non-steroidal anti-inflammatory drugs (NSAIDs), opioids, corticosteroids, muscle relaxants, antidepressants, anticonvulsants and benzodiazepines...
July 2017: Journal—Canadian Dental Association, Journal de L'Association Dentaire Canadienne
Shirley Moreira Alves, Raul Sousa Freitas, Danielle Rocha do Val, Lorena Vasconcelos Vieira, Ellen Lima de Assis, Francisco Isaac Fernandes Gomes, Carlos Alberto de Almeida Gadelha, Tatiane Santi Gadelha, José Thalles Jocelino Gomes de Lacerda, Juliana Trindade Clemente-Napimoga, Vicente de Paulo Teixeira Pinto, Gerardo Cristino Filho, Mirna Marques Bezerra, Hellíada Vasconcelos Chaves
Abelmoschus esculentus is largely cultivated in Northeastern Brazil for medicinal purposes, e.g. inflammatory conditions. This study aimed to evaluate the efficacy of Abelmoschus esculentus lectin (AEL) in reducing formalin-induced temporomandibular joint inflammatory hypernociception in rats. The behavioral experiments were performed in male Wistar rats (180-240 g). Rats were pre-treated (i.v.) with AEL (0.001, 0.01 or 0.1 mg/kg) 30 min before formalin injection ( To analyze the possible effect of opioid pathways on AEL efficacy, animals were pre-treated with naloxone or CTOP (μ opioid receptor antagonist), naltrindole (δ opioid receptor antagonist) or nor-binaltorphimine (κ opioid receptor antagonist) (i...
March 1, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
David Faustino Ângelo, Pedro Morouço, Florencio Monje Gil, Lisete Mónico, Raúl González-Gárcia, Rita Sousa, Lia Neto, Inês Caldeira, Margaret Smith, Susan Smith, David Sanz, Fábio Abade Dos Santos, Mário Pinho, Belmira Carrapiço, Sandra Cavaco, Carla Moura, Nuno Alves, Francisco Salvado, Christopher Little
INTRODUCTION: The role of temporomandibular joint (TMJ) surgery is not well defined due to a lack of quality randomized controlled clinical trials, comparing different TMJ surgical treatments with medical and placebo interventions. The temporomandibular joint interposal study (TEMPOJIMS) is a rigorous preclinical trial divided in 2 phases. In phase 1 the authors investigated the role of the TMJ disc and in phase 2 the authors evaluated 3 different interposal materials. The present work of TEMPOJIMS - phase 1, aims to evaluate histopathologic and imaging changes of bilateral discectomy and discopexy in Black Merino sheep TMJ, using a high-quality trial following the ARRIVE guidelines...
February 2, 2018: Journal of Cranio-maxillo-facial Surgery
Nima Khavanin, Edward H Davidson, Diana Y Lee, Patrick Byrne, Amir H Dorafshar
Concomitant temporomandibular joint (TMJ) transplantation is an obvious advancement in the reconstructive armamentarium for face transplantation in scenarios involving TMJ ankylosis. This study investigates the fidelity of mandibular morphology and explores the feasibility of bilateral mandibular condyle transfer in facial vascularized composite allotransplantation. Geometric analysis was performed on 100 skeletally mature maxillofacial computed tomography scans. Exclusion criteria included mandibular trauma and dentoalveolar disease...
March 1, 2018: Journal of Craniofacial Surgery
John E Mitakides
No abstract text is available yet for this article.
March 2018: Cranio: the Journal of Craniomandibular Practice
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