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https://www.readbyqxmd.com/read/28537867/basaloid-follicular-hamartoma-clinical-dermoscopic-and-histopathological-characteristics-of-case
#1
Ellie Choi, May Liau, Jingxiang Huang, Kong Bing Tan, Derrick Aw
Basaloid follicular hamartoma (BFH) is a rare benign adnexal tumor with variable clinical presentation. We report a case of a 64-year-old man, who presented with an incidental finding of a 3mm hyperpigmented macule on his cheek. Dermoscopy revealed a structureless blue lesion. Histopathology examination showed interconnecting lobules and cords of bland pigmented epithelial cells within the dermal stroma, with the presence of pseudohorncysts. The lesional cells were faintly positive for Bcl2on immunohistochemical staining...
May 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/28525460/coexistent-superscan-and-lincoln-sign-on-bone-scintigraphy
#2
Mukta Kulkarni, Atul Soni, Shubhangi Shetkar, Momin Amer, Amruta Mulavekar, Prathamesh Joshi
A 70-year-old man underwent Tc-methylene diphosphonate scintigraphy for staging of adenocarcinoma prostate. Scintigraphy revealed diffuse increased tracer uptake in skeletal system along with faint renal visualization, a pattern compatible with metastatic superscan. The scintigraphy also revealed increased radiotracer uptake in the body of the mandible-Lincoln sign or black beard sign. Radiological imaging revealed sclerotic lesions throughout the skeleton including the mandible, confirming widespread skeletal metastases...
May 19, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28525452/concomitant-lung-cancer-and-gastrointestinal-stromal-tumor-first-report-of-hypoxia-imaging-with-18f-faza-pet-ct
#3
Paola Mapelli, Elena Incerti, Federico Fallanca, Valentino Bettinardi, Antonia Compierchio, Valeria Masiello, Claudio Doglioni, Francesca Rossetti, Giampiero Negri, Luigi Gianolli, Maria Picchio
A 76-year-old man underwent F-FDG PET/CT to complete staging and characterize a suspicious lung mass. Images showed intense uptake in the lung lesion and faint uptake in correspondence of a gastric mass, which was subsequently biopsied revealing a gastrointestinal stromal tumor. A F-FAZA PET/CT was also performed because of patient's enrollment in a prospective clinical trial (trial registration no. EudraCT 2011-002647-98), showing heterogeneous uptake of F-FAZA in the pulmonary lesion and faint uptake in correspondence of the gastrointestinal stromal tumor...
May 19, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28525332/distribution-and-immunohistochemical-characteristics-of-cocaine-and-amphetamineregulated-transcript-positive-nerve-elements-in-the-pelvic-ganglia-of-the-female-pig
#4
A Zacharko-Siembida, M Matysek, R Szalak, A Radlińska, K Obszańska, M B Arciszewski
Cocaine- and amphetamine-regulated transcript (CART) peptides are widely expressed not only in the brain but also in numerous endocrine/neuroendocrine cells as well as in neurons of the peripheral nervous system. The present study investigated the distribution patterns of CART-like immunoreactivity in the pelvic plexus (PP) of the female pig. The co-expression of CART with principal neurotransmitter markers: choline acetyltransferase (ChAT), tyrosine hydroxylase (TH), serotonin (5-HT) or biologically active neuropeptides: pituitary adenylate cyclase-activating polypeptide (PACAP), substance P (SP), calbindin was analyzed using double immunohistochemical stainings...
March 28, 2017: Polish Journal of Veterinary Sciences
https://www.readbyqxmd.com/read/28522756/influence-of-sex-menstrual-cycle-and-oral-contraceptives-on-cerebrovascular-resistance-and-cardiorespiratory-function-during-valsalva-or-standing
#5
Syed Abidi, Misha Nili, Stephania Serna, Simon Kim, Christopher Hazlett, Heather Edgell
Women experience orthostatic intolerance more than men, and experience faintness more in the early follicular (i.e. low hormone (LH)) compared to the luteal (i.e. high hormone (HH)) phase of the menstrual cycle. Men (n=13, age: 25.8±1.8) and women in the LH (day 2-5; placebo) and HH) (day 18-24; high dose) phases of the menstrual cycle with (OC; n=14, age: 22.0±0.8) or without oral contraceptives (NOC; n=12, age: 21.8±0.5) underwent the Valsalva maneuver and a supine-sit-stand protocol. Blood pressure, normalized stroke volume (SVi), cardiac output index (Qi), heart rate (HR), end-tidal carbon dioxide (ET-CO2), and middle cerebral artery blood velocity (MCA) were measured...
May 18, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28522155/fibroelastic-pseudotumour-elastofibroma-dorsi-detected-by-18-f-fdg-pet-ct-and-by-posttherapy-radioiodine-spect-ct
#6
M Oporto, F Cepa, N Orta, S Rubí, H Navalón, C Peña
Radioiodine uptake in the thyroid tissue, metastasis of differentiated thyroid cancer (DTC), and in other tissues, depends on the expression of sodium-iodide symporter (NIS). Vascular permeability, effusions, inflammation, and other mechanisms may also play a role in the accumulation of radioactive iodine. A 63-year-old woman underwent radioiodine therapy, as well as a post-therapy whole-body scan,as she was suspected of having lung metastasis from thyroid carcinoma. The scan not only showed uptake at the lung metastasis but also a faint diffuse bilateral uptake in the posterior thorax...
May 15, 2017: Revista Española de Medicina Nuclear e Imagen Molecular
https://www.readbyqxmd.com/read/28511446/thromboangitis-obliterans-involving-bilateral-upper-limb-extremities-a-rare-case-report-from-malaysia
#7
Uthamalingam Murali, Mohammad Azhar Anis Ahmad, Fatin Najihah
Thromboangitis Obliterans (TAO) or Buerger's disease is a non-atherosclerotic, occlusive, progressive and highly inflammatory disorder of distal arteries seen predominantly affecting the lower limb in smokers. TAO presenting itself in upper limb or bilaterally involving the upper limb is a very rare entity. We report on a rare case of TAO in a 46-year-old gentleman who presented with bilateral upper extremity digital gangrene with 18 pack-years of smoking. Brachial and radial pulses were palpable bilaterally and were of good volume but right ulnar pulse was faintly felt, while on the left side it was not appreciated due to malunion...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28510436/direct-observations-of-graphene-dispersed-in-solution-by-twilight-fluorescence-microscopy
#8
Yutaka Matsuno, Yu-Uya Sato, Hikaru Sato, Masahito Sano
Graphene and graphene oxide (GO) in solution were directly observed by a newly developed twilight fluorescence (TwiF) microscopy. A nanocarbon dispersion is mixed with a highly concentrated fluorescent dye solution and placed in a cell with a viewing glass at the bottom. TwiF microscopy images the nanocarbon material floating within a few hundred m of the glass surface by utilizing two optical processes to provide a faintly illuminating backlight and visualizes GO as either a dark image by absorption and energy transfer processes or a bright image by alternation of fluorophore chemistry and autofluorescence...
May 16, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28505617/ganglion-cell-complex-in-early-and-intermediate-age-related-macular-degeneration-evidence-by-sd-oct-manual-segmentation
#9
Pedro Camacho, Marco Dutra-Medeiros, Liliana Páris
PURPOSE: To evaluate ganglion cell layer (GCL) and ganglion cell complex (GCC) thickness manually by spectral-domain optical coherence tomography in subjects with early and intermediate age-related macular degeneration (AMD) in 12 locations on the horizontal meridian. METHODS: A total of 450 eyes (specifically, 246 eyes classified as having early/intermediate AMD plus 204 control eyes) were studied. Mann-Whitney U and Kruskal-Wallis tests were used to compare values between the healthy controls and the AMD group and also between the subgroups under study...
May 16, 2017: Ophthalmologica. Journal International D'ophtalmologie
https://www.readbyqxmd.com/read/28476432/fainting-episode-in-a-pacemaker-dependent-patient-with-two-implanted-devices-too-much-of-a-good-thing
#10
Filippo Maria Cauti, Pietro Rossi, Luigi Iaia, Stefano Bianchi
A 73 year old man with CRT-D system and pacemaker dependence was admitted to the emergency department due to a syncopal episode. The device interrogation was performed. An RV ventricular sensing test was executed in VVI mode at 50 b/m. During testing the patient developed transient loss of consciousness with full recovery after stopping the sensing test. Applying asynchronous pacing mode, a pacing spike occurred at a faster rate of 65 b/m without evoking any ventricular capture. Looking at the chest X-ray, we found an abandoned right sided, single chamber VVI pacemaker in a submuscular pocket...
April 22, 2017: Journal of Electrocardiology
https://www.readbyqxmd.com/read/28475511/cutaneous-plasmacytosis-a-clinicopathologic-study-of-a-series-of-cases-and-their-treatment-outcomes
#11
Xiuhui Debra Han, Siong See Joyce Lee, Suat Hoon Tan, Wei-Sheng Chong, See Ket Ng, Melissa Gaik Ming Ooi, Chee Leok Goh
INTRODUCTION: Cutaneous plasmacytosis (CP) is a rare skin disorder characterized by multiple reddish brown nodules with polyclonal plasma cell proliferation. It has most often been reported to affect the trunk but is also known to affect the face and extremities in adults and is predominantly seen in Asians. The etiology is poorly understood, and there is no consensus on treatment methods. METHODS: Five cases diagnosed to have CP were collated from our institution...
April 25, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28469719/systematic-analysis-of-measurement-variability-in-lung-cancer-with-multidetector-computed-tomography
#12
Binghu Jiang, Dan Zhou, Yujie Sun, Jichen Wang
OBJECTIVE: To systematically analyze the nature of measurement variability in lung cancer with multidetector computed tomography (CT) scans. METHODS: Multidetector CT scans of 67 lung cancer patients were analyzed. Unidimensional (Response Evaluation Criteria in Solid Tumor criteria), bidimensional (World Health Organization criteria), and volumetric measurements were performed independently by ten radiologists and were repeated after at least 5 months. Repeatability and reproducibility measurement variations were estimated by analyzing reliability, agreement, variation coefficient, and misclassification statistically...
April 2017: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/28464837/the-correlation-between-malaria-rdt-paracheck-pf-%C3%A2-faint-test-bands-and-microscopy-in-the-diagnosis-of-malaria-in-malawi
#13
Ryoko Makuuchi, Sandy Jere, Nobuchika Hasejima, Thoms Chigeda, January Gausi
BACKGROUND: Faint test bands of Paracheck Pf.® are interpreted as malaria positive according to world health organization (WHO) guideline. However if there are conspicuous number of faint test bands, a performance of Paracheck Pf.® could be influenced depending on whether interpreting faint test bands as malaria positive or negative. Finding out the frequency and accurate interpretation of faint test bands are important to prevent the overdiagnosis and drug resistance. METHODS: A cross-sectional, descriptive study was conducted to find out the frequency of faint test bands and evaluate the performance of Paracheck Pf...
May 2, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28461874/epidemiological-study-of-snakebites-in-ardabil-province-iran
#14
Esmaeil Farzaneh, Nasrin Fouladi, Yousef Shafaee, Zahra Mirzamohammadi, Farnaz Naslseraji, Omid Mehrpour
INTRODUCTION: Average annual incidence of snakebite worldwide is between 5.5 to 1.2 million, and at least 125,000 of them are fatal. In Iran, around 4,500-11,000 snakebites occur annually, and a small number of them are fatal. Snake bites can cause intoxity and immediate death in patients, and the aim of this study was to investigate the epidemiological study of snakebites in Ardabil Province. METHODS: This study was a cross-sectional that has been done on 67 snakebite patients who were admitted to the Imam Khomeini Hospital of Ardabil during 2008-2013...
March 2017: Electronic Physician
https://www.readbyqxmd.com/read/28456877/diagnostic-performance-of-a-computer-assisted-diagnosis-system-for-bone-scintigraphy-of-newly-developed-skeletal-metastasis-in-prostate-cancer-patients-search-for-low-sensitivity-subgroups
#15
Mitsuru Koizumi, Kazuki Motegi, Masamichi Koyama, Takashi Terauchi, Takeshi Yuasa, Junji Yonese
PURPOSE: The computer-assisted diagnostic system for bone scintigraphy (BS) BONENAVI is used to evaluate skeletal metastasis. We investigated its diagnostic performance in prostate cancer patients with and without skeletal metastasis and searched for the problems. METHODS: An artificial neural network (ANN) value was calculated in 226 prostate cancer patients (124 with skeletal metastasis and 101 without) using BS. Receiver operating characteristic curve analysis was performed and the sensitivity and specificity determined (cutoff ANN = 0...
April 29, 2017: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/28444333/a-non-classical-member-of-the-protein-disulfide-isomerase-family-pdi7-of-arabidopsis-thaliana-localizes-to-the-cis-golgi-and-endoplasmic-reticulum-membranes
#16
Christen Y L Yuen, Pengfei Wang, Byung-Ho Kang, Kristie Matsumoto, David A Christopher
Members of the protein disulfide isomerase (PDI)-C subfamily are chimeric proteins containing the thioredoxin (Trx) domain of PDIs, and the conserved N- and C-terminal Pfam domains of Erv41p/Erv46p-type cargo receptors. They are unique to plants and chromalveolates. The Arabidopsis genome encodes three PDI-C isoforms: PDI7, PDI12, and PDI13. Here we demonstrate that PDI7 is a 65-kDa integral membrane glycoprotein expressed throughout many Arabidopsis tissues. Using a PDI7-specific antibody, we show through immunoelectron microscopy that PDI7 localizes to the endoplasmic reticulum (ER) and Golgi membranes in wild-type root tip cells, and was also detected in vesicles...
April 21, 2017: Plant & Cell Physiology
https://www.readbyqxmd.com/read/28435655/a-80-year-old-woman-with-b-cell-prolymphocytic-leukemia
#17
Alparslan Merdin, Jale Yıldız, Sinan Dal Mehmet, Merih Kızıl Çakar, Hikmetullah Batgi, Emre Tekgündüz, Aykut Onursever, Fevzi Altuntaş
Prolymhocytic leukemia (PLL) is a rare subtype of lymphocytic leukemias and its cells are immature lymphocytes. It is divided into 2 subgroups: T-PLL and B-PLL according to the lymphocytic origin of the cells. Discriminating B-PLL from other diseases with clinically-similar features is important because of the different treatment approaches and follow-up programs. Hereby, we report a 80-year-old woman presenting with fatigue, leucocytosis and mild anemia. Her peripheral blood smear evaluation revealed 85% prolymphocytes with moderately condensed nuclear chromatin, prominent nucleoli, and a faintly basophilic cytoplasm...
February 23, 2017: Hematology Reports
https://www.readbyqxmd.com/read/28434730/the-effect-of-vitamin-concentrates-on-the-flavor-of-pasteurized-fluid-milk
#18
E B Yeh, A N Schiano, Y Jo, D M Barbano, M A Drake
Fluid milk consumption in the United States continues to decline. As a result, the level of dietary vitamin D provided by fluid milk in the United States diet has also declined. Undesirable flavor(s)/off flavor(s) in fluid milk can negatively affect milk consumption and consumer product acceptability. The objectives of this study were to identify aroma-active compounds in vitamin concentrates used to fortify fluid milk, and to determine the influence of vitamin A and D fortification on the flavor of milk. The aroma profiles of 14 commercial vitamin concentrates (vitamins A and D), in both oil-soluble and water-dispersible forms, were evaluated by sensory and instrumental volatile compound analyses...
April 20, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28434432/pattern-center-and-distortion-determined-from-faint-diffuse-electron-diffraction-rings-from-amorphous-materials
#19
János L Lábár, Partha P Das
Diffuse rings from amorphous materials sit on a steep background resulting in a monotonically decreasing intensity over scattering vector length, frequently with no clear local maximum that could be used to determine the center of the ring. The novelty of the method reported here is that it successful processes such weak patterns. It is based on separating the angular dependence of the positions of the maxima on the azimuthal angle in the measured two-dimensional pattern for a manually preselected peak. Both pattern center and elliptical distortion are simultaneously refined from this angular dependence...
April 24, 2017: Microscopy and Microanalysis
https://www.readbyqxmd.com/read/28433963/schuklenk-s-critique-of-the-cioms-guidelines-all-procedure-no-substance
#20
Ruth Macklin
In his article on the 2016 revision of the CIOMS International Ethical Guidelines (​1), Udo Schuklenk criticises the guidelines but adds a few words of faint praise. His criticisms are primarily procedural, and comprise the following main points: the guidelines aren't really ethical guidelines; the process used by the work group that wrote the guidelines involves "appeals to authority"; the work group used a method of consensus to reach conclusions on controversial points; the work group consisted of twice the number of participants from the global North as from the global South, yet the guidelines are largely directed at low-resource countries...
March 29, 2017: Indian Journal of Medical Ethics
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