Jiguo Zhang, Houbao Qi, Meihui Li, Zhihong Wang, Xiaofang Jia, Tianyong Sun, Shufa Du, Chang Su, Mengfan Zhi, Wenwen Du, Yifei Ouyang, Pingping Wang, Feifei Huang, Hongru Jiang, Li Li, Jing Bai, Yanli Wei, Xiaofan Zhang, Huijun Wang, Bing Zhang, Qiang Feng
The impact of external factors on the human gut microbiota and how gut microbes contribute to human health is an intriguing question. Here, the gut microbiome of 3,224 individuals (496 with serum metabolome) with 109 variables is studied. Multiple analyses reveal that geographic factors explain the greatest variance of the gut microbiome and the similarity of individuals' gut microbiome is negatively correlated with their geographic distance. Main food components are the most important factors that mediate the impact of host habitats on the gut microbiome...
March 13, 2024: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)