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Skin rejuvenation

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https://www.readbyqxmd.com/read/29334090/supramolecular-photosensitizers-rejuvenate-photodynamic-therapy
#1
Xingshu Li, Songyi Lee, Juyoung Yoon
Owing to its spatiotemporal selectivity and noninvasive nature, photodynamic therapy (PDT) has become a clinically promising approach for the treatment of a wide range of cancers and other diseases. However, the full potential of PDT has not been achieved thus far as a consequence of the lack of optimal photosensitizers (PSs) and/or smart transport/activation strategies. These problems, which unfortunately lie at the core of the PDT paradigm, include the oxygen reliance limits, the effect of PDT on hypoxic tumors, limitations of light penetration, and undesired skin photosensitization induced by "always on" PSs...
January 15, 2018: Chemical Society Reviews
https://www.readbyqxmd.com/read/29320593/injection-depth-in-intradermal-therapy-update-and-correction-of-published-data
#2
Patrick Micheels, Lisa Goodman
BACKGROUND: This paper sought to compare calculated injection depth data with published report claims concerning intradermal therapy and skin rejuvenation of the face, hands, neck, and décolleté. OBJECTIVE: A mathematical formula was employed to assess the injection depth, and data from literature were retrieved and compared with the calculated figures to determine whether the claims about the injection depth proved correct. METHODS: Based on a study by Della Volpe et al...
January 1, 2018: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29320592/injectable-non-animal-stabilized-hyaluronic-acid-as-a-skin-quality-booster-an-expert-panel-consensus
#3
Magda Belmontesi, Francesca De Angelis, Carlo Di Gregorio, Ivano Iozzo, Marina Romagnoli, Giovanni Salti, Matteo Tretti Clementoni
Hyaluronic acid (HA) is used extensively in aesthetic medicine thanks to its documented role in skin rejuvenation. The specific applications of HA-based products are not always fully acknowledged due to a lack of consistent recommendations. In this paper, the authors have summarized available published data on the range of applications of non-animal stabilized hyaluronic acid (NASHA®) gel skin boosters (NSBs) in several anatomical areas and types of patient, as well as their own recommendations. Overall, the panel agreed that a standard initial protocol treatment of up to 3 sessions, followed by a maintenance schedule, would allow patients to improve and then preserve skin quality over time...
January 1, 2018: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29320587/a-randomized-study-to-assess-the-efficacy-of-skin-rejuvenation-therapy-in-combination-with-neurotoxin-and-full-facial-filler-treatments
#4
Steven H Dayan, Thuy-Van T Ho, Jonathan T Bacos, Nimit D Gandhi, Arjun Kalbag, Selika Gutierrez-Borst
<p>BACKGROUND: Although non-surgical treatment options for facial rejuvenation are well-established, the literature remains limited regarding the combined effect of topical skin treatment with filler and neurotoxin on patient appearance and satisfaction. The objectives of this study were to assess the impact of a skin rejuvenation therapy in combination with neurotoxin or hyaluronic acid filler injection on skin quality and general aesthetic improvement as well as on short-term self-esteem.</p> <p>METHODS: From 2015 to 2017, 20 female patients were enrolled in our study and were randomized into two groups...
January 1, 2018: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29309339/punctuated-88-phenol-peeling-for-the-treatment-of-facial-photoaging-a-clinical-and-histopathological-study
#5
Maria Cristina C de Mendonça, Natália N Segheto, Fernando M Aarestrup, Beatriz J V Aarestrup
BACKGROUND: Phenol peeling is considered an important agent in the treatment of facial rejuvenation; however, its use has limitations due to its high potential for side effects. OBJECTIVE: This article proposes a new peeling application technique for the treatment of photoaging, aiming to evaluate, clinically and histopathologically, the efficacy of a new way of applying 88% phenol, using a punctuated pattern. METHODS: The procedure was performed in an outpatient setting, with female patients, on static wrinkles and high flaccidity areas of the face...
January 5, 2018: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/29283463/neck-rejuvenation-by-direct-anterior-medial-cervicoplasty-the-modified-zigzag-plasty-according-to-tschopp
#6
Alexander Konstantinow, Tatjana Fischer, Alexander Zink
BACKGROUND: Conventional cervicofacial rhytidectomy has become the standard treatment of skin excess of the ageing neck. However, some patients want to avoid an extensive surgical procedure, especially if the anterior neck is the predominant problem zone. OBJECTIVE: To report on the efficacy and safety of a zigzag-shaped skin excision combined with platysma plication. METHODS & MATERIALS: We present a retrospective case review series of 6 female patients...
December 28, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29273933/neck-contouring-without-rhytidectomy-in-the-presence-of-excess-skin
#7
Ji H Son, Christina Pindar, Kristopher Katira, Bahman Guyuron
BACKGROUND: Patients with severe neck skin laxity due to excess submental adipose tissue have required either standard rhytidectomy or direct excision of neck skin with Z-plasty and submental lipectomy. Our recent experiences with four patients who declined cervicofacial rhytidectomy demonstrate that submental lipectomy and platysmarrhaphy appear to obtain sufficient improvement. METHODS: The submental area, submandibular area, and lateral neck are injected with local anesthetic...
December 22, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29250711/objective-evaluation-of-the-effects-of-intense-pulsed-light-treatment-on-asian-skin-by-reflectance-confocal-microscopy-analysis
#8
Wenjia Sun, Jiaqiang Wu, Hui Qian, Juemin Zhao, Leihong Xiang, Chengfeng Zhang
This study aimed to evaluate the effect of IPL treatment on Asian skin by reflectance confocal microscopy (RCM) analysis. Ten Asian female volunteers (39~54 years old, Fitzpatrick skin type III~IV) received five monthly IPL treatments. RCM skin images were evaluated, and several skin physiological parameters including thickness of stratum corneum, minimal thickness of epidermis, thickness of basal layer, density of dermal papillae, and mean diameter of papillae capillaries were measured both at baseline and 1 month after the last treatment...
December 18, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/29246280/continuous-astaxanthin-intake-reduces-oxidative-stress-and-reverses-age-related-morphological-changes-of-residual-skin-surface-components-in-middle-aged-volunteers
#9
Natalya E Chalyk, Viktor A Klochkov, Tatiana Y Bandaletova, Nigel H Kyle, Ivan M Petyaev
Oxidative stress accelerates skin aging, and dietary supplementation with antioxidants may alleviate it. Morphological analysis of the residual skin surface components (RSSCs) allows detecting age-related changes in corneocyte desquamation, microbial presence, and lipid droplet size. We hypothesized that continuous ingestion of carotenoid antioxidant astaxanthin (4 mg/d) for 4 weeks could influence RSCC morphology and evaluated RSSC samples taken from middle-aged subjects before and after this dietary intervention...
December 2017: Nutrition Research
https://www.readbyqxmd.com/read/29240854/upregulation-of-extracellular-matrix-genes-corroborates-clinical-efcacy-of-human-fibroblast-derived-growth-factors-in-skin-rejuvenation
#10
Kuniko Kadoya, Elizabeth T Makino, Lily I Jiang, Michael Bachelor, Robin Chung, Priscilla Tan, Tsing Cheng, Gail K Naughton, Rahul C Mehta
<p>Skin care products may use various active ingredients to support skin rejuvenation including growth factors and other molecules that help to regenerate extracellular matrix (ECM) and promote skin repair. The biological effect of skin care products with a strong anti-aging claim was assessed in gene expression analyses using an in vitro human skin model. Application of products containing human fbroblast-derived growth factors resulted in signifcant upregulation of genes encoding ECM components including collagens and elas-tin...
December 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29236557/complications-and-posttreatment-care-following-invasive-laser-skin-resurfacing-a-review
#11
Dan Li, Shi-Bin Lin, Biao Cheng
OBJECTIVE: Laser skin resurfacing (LSR) has been used for facial rejuvenation for the last 20 years. Posttreatment care after LSR is essential to decrease the risk of complications. Currently, no unified standards or criteria exist for invasive LSR posttreatment care. We aimed to identify the optimal wound care timing and choice of specific local, systemic, and general medical measures required to decrease complications. METHODS: We performed a systematic search of the PubMed/MEDLINE electronic databases and included only articles written and published in the English language, with no restrictions on the publication time (year)...
December 13, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/29228145/rejuvenating-the-face-an-analysis-of-100-absorbable-suture-suspension-patients
#12
Michael Patrick Ogilvie, Julius Warren Few, Shikhar Singh Tomur, Chad Michael Teven, Alec James Semersky, Caroline Regan Bruno, Natasha Tamagni Kulick
Background: Absorbable suture suspension (Silhouette InstaLift, Sinclair Pharma, Irvine, CA) is a novel, minimally invasive system that utilizes a specially manufactured synthetic suture to help address the issues of facial aging, while minimizing the risks associated with historic thread lifting modalities. Objectives: The purpose of the study was to assess the safety, efficacy, and patient satisfaction of the absorbable suture suspension system in regards to facial rejuvenation and midface volume enhancement...
December 8, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29224038/skin-tightening-does-it-really-exist
#13
Monica Boen, Monique J Vanaman Wilson, Sabrina Fabi
Skin tightening is one of the cornerstones of skin rejuvenation and is defined as the improvement of skin laxity and crepiness of the skin. There are several energy-based devices that can produce significant skin tightening without surgery, both on and off the face. The mechanisms of skin tightening involve collagen denaturation resulting in collagen shrinkage and tissue tightening, and the wound healing response that generates new collagen and elastin. These hypothesized mechanisms of skin contraction leading to clinical skin tightening have been derived from histological, immunohistochemical, and electron microscope analysis, as well as in vitro and in vivo experiments...
December 2017: Seminars in Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29224031/short-pulsed-laser-for-the-treatment-of-tattoos-pigmented-lesions-scars-and-rejuvenation
#14
Emil A Tanghetti, Kristina Andrea Hoffmann, Klaus Hoffmann
This review describes the use of picosecond lasers for the treatment of tattoos, pigmented lesions, scars, and their use in rejuvenation. These devices have delivered enhanced efficacy for the treatment of tattoos and pigmented lesions when compared to the older 40-50 nanosecond devices. The fractional delivery with the picosecond devices have opened up a new method of rejuvenation for photodamaged skin and the treatment of scars. The delivery of these high-energy short pulses have created zones of injury in the skin referred to as areas of laser-induced optical breakdown...
December 2017: Seminars in Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29224030/advances-in-fractional-technology-for-skin-rejuvenation-skin-tightening-drug-delivery-and-treating-scars-and-skin-defects
#15
Deirdre Connolly, Laura Schilling, Nazanin Saedi
The development of fractional photothermolysis has revolutionized the treatment of skin scarring, rejuvenation, and tightening. By creating targeted microthermal zones and leaving surrounding tissue intact, this concept has provided the field with efficacious results, with less downtime and a better safety profile. This has started to change the paradigm of what is considered first-line treatment for scarring and rejuvenation. While originally applied to nonablative lasers, fractionation has now been employed in ablative, quality-switched, picosecond, and novel hybrid fractional lasers...
December 2017: Seminars in Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29218478/the-rejuvenating-effect-and-tolerability-of-an-auto-cross-linked-hyaluronic-acid-on-d%C3%A3-colletage-a-pilot-prospective-study
#16
Andrea Alessandrini, Kseniya Tretyakova
BACKGROUND: A novel auto-cross-linked hyaluronic acid formulation (HA-ACP) has been proposed as a treatment for skin rejuvenation. This prospective pilot study aims to assess its tolerability and performance in the treatment of skin aging of the décolletage. METHODS: Fifteen women (mean age 49.0 ± 8.0  (range 30-65)) who complained about the appearance of their décolletage were prospectively enrolled and treated with three sets of HA-ACP (IAL-SYSTEM ACP®) intradermal injections, administered three weeks apart...
December 7, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29165881/nerve-injury-associated-with-high-intensity-focused-ultrasound-a-case-report
#17
Angkana Sathaworawong, Rungsima Wanitphakdeedecha
Skin laxity is a common cosmetic concern in middle-aged women. High-intensity focused ultrasound (HIFU) is one of noninvasive modalities that provides safe and effective improvement in skin laxity and tightening with minimal adverse effects. Concerning an extensive use of HIFU for facial rejuvenation, dermatologists should be aware of potential adverse effects of HIFU treatment. We herein present a case of 33-year-old Thai female with facial nerve injury after HIFU treatment for skin laxity.
November 22, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29164778/open-label-study-assessing-the-efficacy-and-tolerability-of-topical-skincare-and-sun-protection-products-following-intense-pulsed-light-treatment
#18
Isabela T Jones, Isabella Guiha, Sabrina G Fabi
BACKGROUND: The visible signs of photodamage can be improved by intense pulsed light (IPL). Active ingredients in cosmeceuticals also have effects on skin quality and pigmentation, and can camouflage post-treatment side effects. Combination therapies utilizing different treatment modalities have been shown to optimize clinical outcomes for skin rejuvenation and patient satisfaction. AIM: To evaluate the efficacy of a combination of IPL with a daily topical skincare and sunscreen regimen for the treatment of facial photodamage and for the improvement of IPL treatment tolerability...
November 21, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29160000/new-soft-tissue-filler-derived-from-autologous-keratin-and-fibroblast-for-neck-wrinkles
#19
Yue Wang, Bingqing Wang, Qingguo Zhang, Jiguang Ma
OBJECTIVE: To assess the effectiveness of injection of autologous keratin gel and fibroblast for neck aging as soft tissue filler. MATERIALS AND METHODS: Totally 30 volunteers received treatment of autologous keratin and fibroblast for neck wrinkles and 5 of them received hyaluronic acid (HA) treatment as control. Clinical features of the volunteers were collected at 1st, 3rd, 6th, 12th, and 24th months after treatment. The volunteers were independently assessed using Lemperle's methods at different time points...
November 21, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29133982/combined-aesthetic-interventions-for-prevention-of-facial-ageing-and-restoration-and-beautification-of-face-and-body
#20
Sabrina Fabi, Tatjana Pavicic, André Braz, Jeremy B Green, Kyle Seo, Jani Aj van Loghem
The Merz Institute of Advanced Aesthetics Expert Summit was held in Prague, Czech Republic, from 19-20 November 2016. The meeting had a distinct advisory board character and invited aesthetic practitioners from all over the world to hear an international faculty present a range of keynote lectures and conduct live injection sessions with an emphasis on recent developments in combination aesthetic interventions for face and body rejuvenation and beautification. Aging is associated with changes in bones, muscles, ligaments, adipose tissue, and skin and, moreover, involves interactions among these tissue types...
2017: Clinical, Cosmetic and Investigational Dermatology
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