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Sacrococcygeal teratoma

Hemonta Kr Dutta, Pronami Borah, Mauchumi Baruah
Extragonadal teratomas are rarely encountered in infants and children. These tumors are reported in retroperitoneum, floor of the mouth, mediastinum, craniofacial region or even in the solid organs of the body. Most of the gluteal teratomas reported in the literature are in fact, lateralized sacrococcygeal teratomas. We are reporting a case of unilateral big gluteal teratoma in a 6-year-old girl. The tumor did not have any connection with the sacrum or coccyx and was successfully removed. Histology showed well-differentiated bowel as well as fetiform structures...
October 2016: Journal of Indian Association of Pediatric Surgeons
M Slodki, K Piatek, K Wieckowska, M Respondek-Liberska
No abstract text is available yet for this article.
September 2016: Ultrasound in Obstetrics & Gynecology
Rahul Gupta, Vinita Chaturvedi
No abstract text is available yet for this article.
August 8, 2016: Indian Pediatrics
Robert E Emerson, Chia-Sui Kao, John N Eble, David J Grignon, Mingsheng Wang, Shaobo Zhang, Xiaoyan Wang, Rong Fan, Timothy A Masterson, Lawrence M Roth, Liang Cheng
AIMS: Sacrococcygeal teratomas are rare tumours that occur most frequently in neonates, although adult cases also occur. The molecular pathogenesis of these tumours and their long-term prognosis is uncertain. We investigated the i(12p) status of a large number of primary sacrococcygeal teratomas in both children and adults, including cases with malignant germ cell tumour elements. METHODS AND RESULTS: Fifty-four sacrococcygeal teratoma specimens from 52 patients were identified, and available follow-up information was obtained...
August 13, 2016: Histopathology
Marijke E B Kremer, Lianne M Wellens, Joep P M Derikx, Robertine van Baren, Hugo A Heij, Marc H W A Wijnen, René M H Wijnen, David C van der Zee, L W Ernest van Heurn
BACKGROUND: A small percentage of neonates with sacrococcygeal teratoma die shortly after birth from hemorrhagic complications. The incidence of and risk factors associated with hemorrhagic mortality are unknown. In this multicenter study we determined the incidence of early death in neonates born with SCT and evaluated potential risk factors for hemorrhagic mortality. METHODS: 235 children with SCT treated from 1970 to 2010 in the Netherlands were retrospectively included...
November 2016: Journal of Pediatric Surgery
Michał Krekora, Katarzyna Zych-Krekora, Marek Blitek, Marcin Kęsiak, Anna Piaseczna-Piotrowska, Stanisław Łukaszek, Grzegorz Krasomski, Maciej Słodki, Krzysztof Szaflik, Maria Respondek-Liberska
Prenatal ultrasound at the 20th week of gestation revealed a 3-cm tumour in the sacrococcygeal area. Initially, a sacrococcygeal teratoma was suspected on the basis of fetal ultrasonography, which revealed normal heart anatomy and an increasing tumour mass. The diagnosis was then changed to fetus in fetu or teratoma. Prenatal magnetic resonance imaging at the 34th week of pregnancy confirmed the ultrasound diagnosis. No other anomalies were found. Elective caesarean section was performed at term. The care team included a paediatric surgeon, obstetricians, neonatologists, midwives, and an anesthesiologist...
May 2016: Ultrasound: Journal of the British Medical Ultrasound Society
Sahar Eftekharzadeh, Sorena Keihani, Mehdi Fareghi, Alireza Alamsahebpour, Abdol-Mohammad Kajbafzadeh
Type IV sacrococcygeal teratoma is a rare pediatric tumor that is confined to the presacral area with no external component. The signs and symptoms often arise due to mass effect and compression of adjacent organs. Urinary retention is an uncommon presenting symptom in these patients. A wide spectrum of imaging findings may be encountered in cases with sacrococcygeal teratoma because of variability of tumor size and components. We hereby present a unique magnetic resonance urography finding in a type IV sacrococcygeal teratoma which caused bladder displacement...
2016: Case Reports in Urology
Ramagopal G, Guru R, Suresh P, Moorthy G, Devi Lu
No abstract text is available yet for this article.
July 2016: APSP Journal of Case Reports
Bayram Ali Dorum, Nilgün Köksal, Hilal Özkan, Sabahattin Karakaya, Ahsen Karagözlü Akgül
Sacrococcygeal teratoma (SCT) is rarely associated with syndromes. We report a female newborn with a prenatal diagnosis of small sacrococcygeal teratoma and postnatally diagnosed as having trisomy 13. The sacrococcygeal teratoma was excised. It was reported as mature teratoma. The child succumbed to sepsis postoperatively.
July 2016: APSP Journal of Case Reports
Kristen Zhelnin, Grant Gebhard, David Mirsky, Scott Oliver, Mark A Lovell, Csaba Galambos, Timothy Crombleholme, Emily McCourt
Intraocular teratomas are rare neoplasms with only three previously reported cases. We present the fourth case of intraocular teratoma and the second associated with sacrococcygeal teratoma. While the nature of the association between intraocular teratomas and sacrococcygeal teratomas is unclear it suggests a need for careful ophthalmologic follow-up of infants with congenital sacrococcygeal teratomas.
July 6, 2016: Pediatric and Developmental Pathology
Martin J C van Gemert, Peter G J Nikkels, K Marieke Paarlberg, Jeroen P H M van den Wijngaard, Helena M Gardiner
BACKGROUND: We recently published pump/acardiac umbilical venous diameter (UVD) ratios, representing the pump twin's excess cardiac output fraction, of 27 acardiac twin pregnancies. There was a clear separation between the 17 pump twins that had life-threatening complications and the 10 that did not. The hypothesis of this study is that placental chorangioma and sacrococcygeal teratoma (SCT), tumors whose perfusion also causes high-output complications, have the same fetal outcome as pump twins when perfusion of the tumor requires the same excess cardiac output fraction...
September 2016: Birth Defects Research. Part A, Clinical and Molecular Teratology
Smaranika Choudhury, Manpreet Kaur, Maitree Pandey, Aruna Jain
No abstract text is available yet for this article.
May 2016: Indian Journal of Anaesthesia
P C Browne, S Adam, M Badr, C R Brooks, J Edwards, P Walker, S Mohamed, A R Gregg
Partial trisomy of the 10q region was originally reported in 1979 [1]. For 25 years, the diagnosis was made microscopically based on large, visible insertions in the region identified by karyotype analysis. Previous case reports have included both unbalanced translocations and large duplications/insertions in the 10q region [2]. Probands with partial trisomy 10q syndrome often have an abnormal phenotype that may include developmental delay [3-5], craniofacial abnormalities [3, 5], talipes (clubfoot) [2], microcephaly [2-4], or congenital heart disease [2-6]...
May 17, 2016: Journal of Neonatal-perinatal Medicine
Binod Bade Shrestha, Pradeep Ghimire, Dilasma Ghartimagar, Bishnu Jwarchan, Subita Lalchan, Mikesh Karmacharya
Complete mature brain tissue in sacrococcygeal region is a rare congenital anomaly in a newborn, which usually is misdiagnosed for sacrococcygeal teratoma. Glial tumor-like ependymoma is also common in sacrococcygeal area but mostly appears later in life. We present a case of complete heterotopic brain tissue in the sacrococcygeal region. The patient underwent total excision of mass with coccygectomy. To our knowledge it is the second case being reported.
2016: Journal of Surgical Case Reports
Swetha Lakshmi Narla, Sheba Jacob, Ann Kurian, Ashok Parameswaran
Teratomas are neoplasms comprising of tissues derived from more than one germ layer. Most common sites are gonads, sacrococcygeal, mediastinal, retroperitoneal, and pineal region. Here, we report a case of 2 -year-old previously healthy female toddlerwho presented with fever and right upper quadrant abdominal pain. Magnetic resonance imaging (MRI) of the abdomen revealed a right suprarenal nonenhancing cystic mass. Focal calcification was seen in the inferomedial aspect of the cyst. Complete surgical resection of the right adrenal gland was done...
April 2016: Indian Journal of Pathology & Microbiology
Jose L Peiró, Lourenço Sbragia, Federico Scorletti, Foong Y Lim, Aimen Shaaban
Fetal teratomas are the most common tumors diagnosed prenatally. The majority of these tumors are benign and cured by complete resection of the mass during the neonatal period. Prenatal diagnosis has improved the perinatal management of these lesions and especially for the teratomas that might benefit from fetal intervention. A comprehensive prenatal evaluation including conventional ultrasounds, Doppler, echocardiography and fetal MRI, is essential for an effective counseling and perinatal management. Antenatal counseling helps the parents to better understand the natural history, fetal intervention, and perinatal management of these tumors, which differ dramatically depending on their size and location...
July 2016: Pediatric Surgery International
Kelly M Cunningham, Govind B Chavhan, Kelly E Ainsworth
OBJECTIVE: To describe the imaging characteristics of sacrococcygeal teratomas and to review appropriate diagnostic evaluation and management. CLINICAL FEATURES: 12-year-old otherwise healthy, asymptomatic female with an incidental pelvic mass found on routine scoliosis radiographs. INTERVENTION AND OUTCOME: The pelvic mass was further evaluated by MRI and CT scan. Management consisted of successful surgical resection with no postoperative complications...
March 2016: Journal of the Canadian Chiropractic Association
Anna Raciborska, Katarzyna Bilska, Jadwiga Węcławek-Tompol, Marek Ussowicz, Monika Pogorzała, Joanna Janowska, Magdalena Rychłowska-Pruszyńska, Carlos Rodriguez-Galindo, Ewa Helwich
BACKGROUND: Advances in multidisciplinary care for pediatric cancer have resulted in significant improvement in cure rates over the last decades; however, these advances have not been uniform across all age groups. Cancer is an important cause of perinatal mortality, yet the full spectrum of malignant neoplasms in newborns is not well defined. METHODS: The authors have reviewed the clinical features and outcomes of 37 newborns with congenital malignant tumors treated at three referral centers in North, Central, and South Poland between 1980 and 2014...
August 2016: Pediatrics and Neonatology
Tugba Sarac Sivrikoz, Recep Has, Aytul Corbacioglu Esmer, Ibrahim Kalelioglu, Atil Yuksel, Orhun Cig Taskin
Tethered spinal cord is mostly caused by myelomeningocele and lipomyelomeningocele, while dermal sinus tract, diastematomyelia, lipoma, tumor, thickened/tight filum terminale, spinal trauma, and spinal surgery are among the other causes. Prenatal diagnosis of tethered cord has been reported, and it is usually associated with neural tube defects. We present an atypical presentation of a tethered spinal cord, which was associated with a sacrococcygeal teratoma and was diagnosed in the 23rd week of pregnancy by ultrasonography...
October 2016: Journal of Clinical Ultrasound: JCU
Malgorzata Wojcik, Anna Kalicka-Kasperczyk, Teresa Luszawska-Kutrzeba, Walentyna Balwierz, Jerzy B Starzyk
Cushing syndrome due to ectopic secretion of ACTH in infants is rare. The treatment of choice is radical resection of the tumour in combination with pre-operative chemotherapy using steroidogenesis inhibitors if necessary. If radical surgery is not possible, palliative treatment of hypercortisolemia is recommended. The most frequently used drug in infants is ketoconazole. Experience with the use of metyrapone is poor. We report an 8-month-old female infant with congenital immature sacrococcygeal teratoma secreting AFP, beta hCG and ACTH who had undergone non-radical resection of the tumour mass and was receiving standard risk chemotherapy (vinblastine, bleomycin, and cisplatin)...
December 2015: Neuro Endocrinology Letters
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