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Sacrococcygeal teratoma

Yi Wang, Yeming Wu, Lifeng Wang, Xiaojun Yuan, Mawei Jiang, Yuhua Li
BACKGROUND Sacrococcygeal teratoma (SCT) is a relatively uncommon tumor. Recurrence with poor survival and anorectal dysfunction are the 2 leading problems for patients. Here, we would review the clinic features of patients with SCTs in our hospital to identify risk factors of recurrent SCTs and to analyze anorectal functional sequelae. MATERIAL AND METHODS A retrospective review of all patients with SCTs in our center between 2007 and 2013 was performed. We analyzed the recorded data on each patient and performed follow-up through phone calls...
January 2, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Jeffrey M Denney, Christy Stanley, Lou Ann Armstrong, Jayne Marshall, Bethany Settle, Chad Haldeman-Englert
No abstract text is available yet for this article.
December 27, 2016: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
Kathryn M Maselli, Andrea Badillo
Historically, the gold standard for the treatment of congenital malformations has been planned delivery at tertiary care center with attempted post-natal repair or amelioration of the lesion. Over the last few decades however, rapid advances in imaging and instrumentation technology combined with superior knowledge of fetal pathophysiology has led to the development of novel intrauterine interventions for most common fetal anomalies. Great success has already been seen the treatment of previous devastating anomalies such as myelomeningocele (MMC), congenital cystic malformations of the lung, twin-twin transfusion, and sacrococcygeal teratomas...
October 2016: Annals of Translational Medicine
Claire E Graves, Olajire Idowu, John Zovickian, Dachling Pang, Sunghoon Kim
En bloc removal of the coccyx during sacrococcygeal teratoma resection is necessary to decrease the risk of recurrence. However, variable anatomy often makes the border between the coccyx and sacrum difficult to identify. We describe the use of intraoperative lateral pelvic X-ray to localize this border and ensure complete coccygectomy.
November 17, 2016: Pediatric Surgery International
Ioan Sarbu, Demetra Socolov, Razvan Socolov, Ingrith Miron, Mioara Trandafirescu, Smaranda Diaconescu, Carmen Iulia Ciongradi
INTRODUCTION: Sacrococcygeal teratoma (SCT) is a rare tumor in the general population, arising from multipotent stem cells. Whereas most of the cases diagnosed postnatally have good prognosis, the rate of mortality and morbidities associated with prenatally diagnosed SCT remain high, with a reported mortality rate of 30% to 50%. The outcome of fetal SCT can be unpredictable, with some cases with slow growth during fetal life, whereas others grow rapidly, causing multiple complications; also, some of these tumor will develop triggering fetal (preterm delivery, high-output cardiac failure, hydrops fetalis, intrauterine death) or maternal complications (distocia, placentomegaly, maternal mirror syndrome-preeclampsia)...
October 2016: Medicine (Baltimore)
Rachel A Egler, Yasmin Gosiengfiao, Heidi Russell, Jonathan E Wickiser, A Lindsay Frazier
BACKGROUND: Sacrococcygeal teratoma (SCT) is the most common germ cell tumor (GCT) of infancy. Up to 35% of infants may have malignant elements. The standard of care for SCT with malignant elements (SCT-ME) has been surgery and chemotherapy. However, cases where low-stage SCT-ME have been successfully observed following resection have been reported. PROCEDURE: To better understand the outcomes of low-stage SCT-ME that do not receive chemotherapy, we reviewed SCT pathology reports from five children's hospitals from 1999 to 2009...
October 27, 2016: Pediatric Blood & Cancer
Hemonta Kr Dutta, Pronami Borah, Mauchumi Baruah
Extragonadal teratomas are rarely encountered in infants and children. These tumors are reported in retroperitoneum, floor of the mouth, mediastinum, craniofacial region or even in the solid organs of the body. Most of the gluteal teratomas reported in the literature are in fact, lateralized sacrococcygeal teratomas. We are reporting a case of unilateral big gluteal teratoma in a 6-year-old girl. The tumor did not have any connection with the sacrum or coccyx and was successfully removed. Histology showed well-differentiated bowel as well as fetiform structures...
October 2016: Journal of Indian Association of Pediatric Surgeons
M Slodki, K Piatek, K Wieckowska, M Respondek-Liberska
No abstract text is available yet for this article.
September 2016: Ultrasound in Obstetrics & Gynecology
Rahul Gupta, Vinita Chaturvedi
No abstract text is available yet for this article.
August 8, 2016: Indian Pediatrics
Robert E Emerson, Chia-Sui Kao, John N Eble, David J Grignon, Mingsheng Wang, Shaobo Zhang, Xiaoyan Wang, Rong Fan, Timothy A Masterson, Lawrence M Roth, Liang Cheng
AIMS: Sacrococcygeal teratomas are rare tumours that occur most frequently in neonates, although adult cases also occur. The molecular pathogenesis of these tumours and their long-term prognosis is uncertain. We investigated the i(12p) status of a large number of primary sacrococcygeal teratomas in both children and adults, including cases with malignant germ cell tumour elements. METHODS AND RESULTS: Fifty-four sacrococcygeal teratoma specimens from 52 patients were identified, and available follow-up information was obtained...
January 2017: Histopathology
Marijke E B Kremer, Lianne M Wellens, Joep P M Derikx, Robertine van Baren, Hugo A Heij, Marc H W A Wijnen, René M H Wijnen, David C van der Zee, L W Ernest van Heurn
BACKGROUND: A small percentage of neonates with sacrococcygeal teratoma die shortly after birth from hemorrhagic complications. The incidence of and risk factors associated with hemorrhagic mortality are unknown. In this multicenter study we determined the incidence of early death in neonates born with SCT and evaluated potential risk factors for hemorrhagic mortality. METHODS: 235 children with SCT treated from 1970 to 2010 in the Netherlands were retrospectively included...
November 2016: Journal of Pediatric Surgery
Michał Krekora, Katarzyna Zych-Krekora, Marek Blitek, Marcin Kęsiak, Anna Piaseczna-Piotrowska, Stanisław Łukaszek, Grzegorz Krasomski, Maciej Słodki, Krzysztof Szaflik, Maria Respondek-Liberska
Prenatal ultrasound at the 20th week of gestation revealed a 3-cm tumour in the sacrococcygeal area. Initially, a sacrococcygeal teratoma was suspected on the basis of fetal ultrasonography, which revealed normal heart anatomy and an increasing tumour mass. The diagnosis was then changed to fetus in fetu or teratoma. Prenatal magnetic resonance imaging at the 34th week of pregnancy confirmed the ultrasound diagnosis. No other anomalies were found. Elective caesarean section was performed at term. The care team included a paediatric surgeon, obstetricians, neonatologists, midwives, and an anesthesiologist...
May 2016: Ultrasound: Journal of the British Medical Ultrasound Society
Sahar Eftekharzadeh, Sorena Keihani, Mehdi Fareghi, Alireza Alamsahebpour, Abdol-Mohammad Kajbafzadeh
Type IV sacrococcygeal teratoma is a rare pediatric tumor that is confined to the presacral area with no external component. The signs and symptoms often arise due to mass effect and compression of adjacent organs. Urinary retention is an uncommon presenting symptom in these patients. A wide spectrum of imaging findings may be encountered in cases with sacrococcygeal teratoma because of variability of tumor size and components. We hereby present a unique magnetic resonance urography finding in a type IV sacrococcygeal teratoma which caused bladder displacement...
2016: Case Reports in Urology
Ramagopal G, Guru R, Suresh P, Moorthy G, Devi Lu
No abstract text is available yet for this article.
July 2016: APSP Journal of Case Reports
Bayram Ali Dorum, Nilgün Köksal, Hilal Özkan, Sabahattin Karakaya, Ahsen Karagözlü Akgül
Sacrococcygeal teratoma (SCT) is rarely associated with syndromes. We report a female newborn with a prenatal diagnosis of small sacrococcygeal teratoma and postnatally diagnosed as having trisomy 13. The sacrococcygeal teratoma was excised. It was reported as mature teratoma. The child succumbed to sepsis postoperatively.
July 2016: APSP Journal of Case Reports
Kristen Zhelnin, Grant Gebhard, David Mirsky, Scott Oliver, Mark A Lovell, Csaba Galambos, Timothy Crombleholme, Emily McCourt
Intraocular teratomas are rare neoplasms with only three previously reported cases. We present the fourth case of intraocular teratoma and the second associated with sacrococcygeal teratoma. While the nature of the association between intraocular teratomas and sacrococcygeal teratomas is unclear it suggests a need for careful ophthalmologic follow-up of infants with congenital sacrococcygeal teratomas.
July 6, 2016: Pediatric and Developmental Pathology
Martin J C van Gemert, Peter G J Nikkels, K Marieke Paarlberg, Jeroen P H M van den Wijngaard, Helena M Gardiner
BACKGROUND: We recently published pump/acardiac umbilical venous diameter (UVD) ratios, representing the pump twin's excess cardiac output fraction, of 27 acardiac twin pregnancies. There was a clear separation between the 17 pump twins that had life-threatening complications and the 10 that did not. The hypothesis of this study is that placental chorangioma and sacrococcygeal teratoma (SCT), tumors whose perfusion also causes high-output complications, have the same fetal outcome as pump twins when perfusion of the tumor requires the same excess cardiac output fraction...
September 2016: Birth Defects Research. Part A, Clinical and Molecular Teratology
Smaranika Choudhury, Manpreet Kaur, Maitree Pandey, Aruna Jain
No abstract text is available yet for this article.
May 2016: Indian Journal of Anaesthesia
P C Browne, S Adam, M Badr, C R Brooks, J Edwards, P Walker, S Mohamed, A R Gregg
Partial trisomy of the 10q region was originally reported in 1979 [1]. For 25 years, the diagnosis was made microscopically based on large, visible insertions in the region identified by karyotype analysis. Previous case reports have included both unbalanced translocations and large duplications/insertions in the 10q region [2]. Probands with partial trisomy 10q syndrome often have an abnormal phenotype that may include developmental delay [3-5], craniofacial abnormalities [3, 5], talipes (clubfoot) [2], microcephaly [2-4], or congenital heart disease [2-6]...
May 17, 2016: Journal of Neonatal-perinatal Medicine
Binod Bade Shrestha, Pradeep Ghimire, Dilasma Ghartimagar, Bishnu Jwarchan, Subita Lalchan, Mikesh Karmacharya
Complete mature brain tissue in sacrococcygeal region is a rare congenital anomaly in a newborn, which usually is misdiagnosed for sacrococcygeal teratoma. Glial tumor-like ependymoma is also common in sacrococcygeal area but mostly appears later in life. We present a case of complete heterotopic brain tissue in the sacrococcygeal region. The patient underwent total excision of mass with coccygectomy. To our knowledge it is the second case being reported.
2016: Journal of Surgical Case Reports
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