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https://www.readbyqxmd.com/read/29774649/end-of-life-trajectory-of-coping-and-self-care-of-patients-with-idiopathic-pulmonary-fibrosis-a-meta-synthesis-using-meta-ethnography
#1
Yasuko Igai
AIM: This study aimed to extract patient narratives regarding the end-of-life trajectory of their self-care and coping experiences as patients with idiopathic pulmonary fibrosis and to use meta-ethnography to discover common metaphors of their experience in order to inform the development of nursing interventions. METHODS: A comprehensive search of qualitative research using electronic databases, in English and Japanese, regarding patients with IPF, identified four articles...
May 17, 2018: Japan Journal of Nursing Science: JJNS
https://www.readbyqxmd.com/read/29772916/home-oxygen-therapy-for-bronchiolitis-an-evaluation-of-the-primary-care-providers-experience-at-sea-level
#2
Erin E Dunbar, Michelle L Macy, James A Cranford, Nicole Sroufe, Marie Lozon, Marisa C Louie
Despite 90% of primary care providers at altitude reporting experience with home oxygen therapy for hypoxemic, otherwise well infants, its use at sea level is not well described. Our objective was to understand experience with home oxygen at sea level and determine potential barriers and benefits of its use. We surveyed all pediatricians and family medicine providers within a 30-mile radius of our pediatric hospital from May 2016 to December 2016. Forty-three percent of providers responded. Few (8%) had any experience with home oxygen therapy for bronchiolitis...
May 1, 2018: Clinical Pediatrics
https://www.readbyqxmd.com/read/29768899/preparation-of-graphene-oxide-based-ink-for-inkjet-printing
#3
Peiwen Li, Cheng-An Tao, Bangyun Wang, Jian Huang, Taohai Li, Jianfang Wang
Fabrication of graphene-based conductive circuits via inkjet printing processes would be very significant, but preparation of graphene inks which can be used in ordinary household inkjet printer is still a challenge. Graphene oxide (GO) is an important graphene derivative with good dispersion properties in water, because it has a lot of oxygen-containing functional groups. In this paper, the relationship between the concentration of GO and the viscosity and surface tension of its dispersion were studied first, GO were prepared by modified Hummers' method...
January 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29765003/passive-versus-active-circuit-during-invasive-mechanical-ventilation-in-subjects-with-amyotrophic-lateral-sclerosis
#4
Elisa De Mattia, Elisa Falcier, Andrea Lizio, Christian Lunetta, Valeria A Sansone, Nicola Barbarito, Barbara Garabelli, Marino Iatomasi, Elisabetta Roma, Fabrizio Rao, Annalisa Carlucci
BACKGROUND: Until recently, it has been considered essential to maintain the use of a double-limb circuit in patients with amyotrophic lateral sclerosis (ALS) to avoid rebreathing expired air during invasive mechanical ventilation. Currently, life-sustaining home ventilators can work with a single, lighter circuit that is easier to manage. Our aim was to evaluate the effectiveness and safety of a single-limb circuit with intentional leaks (passive circuit) in comparison with a circuit with an expiratory valve (active circuit), in subjects with ALS who use invasive home ventilation...
May 15, 2018: Respiratory Care
https://www.readbyqxmd.com/read/29763411/characteristics-and-health-care-resource-use-of-subjects-with-copd-in-the-year-before-initiating-lama-monotherapy-or-lama-laba-combination-therapy-a-u-s-database-study
#5
Saurabh Nagar, Jeetvan Patel, Richard H Stanford
PURPOSE: To characterize subjects with chronic obstructive pulmonary disease (COPD) newly initiated on long-acting muscarinic antagonists (LAMA) or dual LAMA/long-acting β2-adrenergic agonist (LABA) therapy. DESIGN: This pilot/preliminary analysis was a retrospective crosssectional study of subjects with COPD from the Optum Impact National Managed Care Benchmark Database. METHODOLOGY: Subjects with at least one LAMA prescription in the index period (July 2008-June 2009) were included and stratified by treatment...
May 2018: Managed Care
https://www.readbyqxmd.com/read/29762884/the-use-of-overnight-oximetry-in-neonates-a-literature-review
#6
REVIEW
Anndrea Flint, Mark W Davies
There is much debate between neonatologists and paediatricians about appropriate oxygen saturation targets for babies with chronic neonatal lung disease (CNLD). Overnight oximetry is used to guide the fraction of inspired oxygen to use. We did this literature review to examine the current literature on the use of overnight oximetry in term infants, preterm infants and babies with CNLD (especially relevant to ex-preterm babies with CNLD going home on oxygen). We reviewed the literature from January 1990 to October 2017 by searching the following databases: Cochrane Central Register of Controlled Trials, The Joanna Briggs Institute, CINAHL, MEDLINE, Scopus, EMBASE, ProQuest and Science Direct...
May 15, 2018: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/29757890/pediatric-carbon-monoxide-poisoning-in-southern-israel-a-cross-sectional-study
#7
Yariv Fruchtman, Zvi H Perry, Tom Leibson, Liat Vered Cohen, Matitiahu Lifshitz, Eugene Leibovitz
OBJECTIVES: This study aimed to describe the epidemiology and clinical burden of unintended carbon monoxide (CO) poisoning among children in the Negev region of southern Israel. METHODS: This was a cross-sectional retrospective study of CO poisoning patients admitted to Soroka University Medical Center in 2011 through 2015. RESULTS: Overall, 43 cases of CO poisoning were recorded among children younger than 18 years. Five patients died, all upon admission...
May 2, 2018: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29751818/harnessing-the-evolutionary-information-on-oxygen-binding-proteins-through-support-vector-machines-based-modules
#8
Selvaraj Muthukrishnan, Munish Puri
OBJECTIVES: The arrival of free oxygen on the globe, aerobic life is becoming possible. However, it has become very clear that the oxygen binding proteins are widespread in the biosphere and are found in all groups of organisms, including prokaryotes, eukaryotes as well as in fungi, plants, and animals. The exponential growth and availability of fresh annotated protein sequences in the databases motivated us to develop an improved version of "Oxypred" for identifying oxygen-binding proteins...
May 11, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29742287/a-mobile-health-technology-enabled-home-based-intervention-to-treat-frailty-in-adult-lung-transplant-candidates-a-pilot-study
#9
Jonathan P Singer, Allison Soong, Alan Bruun, Ayana Bracha, Greg Chin, Steven R Hays, Jasleen Kukreja, Julia Rigler, Jeff A Golden, John R Greenland, Chris Garvey
BACKGROUND: Frailty is prevalent in lung transplant candidates (LTC) and is associated with waitlist delisting or death. We performed a pilot study to assess the safety and feasibility of a home-based, mobile-health technology facilitated intervention to treat frailty in LTC. METHODS: We performed an 8-week, non-randomized, home-based exercise and nutrition intervention in LTC with Short Physical Performance Battery (SPPB) frailty scores of ≤11. The intervention utilized a customized, mobile device application ("app") enabling monitoring and progression of the intervention in real-time...
May 9, 2018: Clinical Transplantation
https://www.readbyqxmd.com/read/29740931/antimicrobial-prescription-in-patients-dying-from-chronic-obstructive-pulmonary-disease
#10
John Taverner, Lauren Ross, Claire Bartlett, M Luthe, J Ong, Louis Irving, Natasha Smallwood
INTRODUCTION: Despite rising antimicrobial resistance, treatment guidelines for COPD exacerbations are frequently ignored. Patients with terminal conditions are often prescribed antimicrobials despite the goal of care to reduce burdensome treatments. The appropriateness of antimicrobials in patients dying from an exacerbation of COPD is unknown. AIM: To review antimicrobial prescription at the time of death in patients who died from COPD. METHODS: A retrospective medical record audit was performed for 475 patients who died over twelve years (2004-2015)...
May 9, 2018: Internal Medicine Journal
https://www.readbyqxmd.com/read/29740015/effects-of-5-aminolevulinic-acid-supplementation-on-home-based-walking-training-achievement-in-middle-aged-depressive-women-randomized-double-blind-crossover-pilot-study
#11
Hiroshi Suzuki, Shizue Masuki, Akiyo Morikawa, Yu Ogawa, Yoshi-Ichiro Kamijo, Kiwamu Takahashi, Motowo Nakajima, Hiroshi Nose
Depressive patients often experience difficulty in performing exercise due to physical and psychological barriers. We examined the effects of 5-aminolevulinic acid (ALA) with sodium ferrous citrate (SFC) supplementation during home-based walking training in middle-aged depressive women. Nine outpatients [53 ± 8 (SD) yr] with major depressive disorder participated in the pilot study with randomized, placebo-controlled, double-blind crossover design. They underwent two trials for 7 days, each performing interval walking training (IWT) with ALA + SFC (ALA + SFC) or placebo supplement intake (PLC) intermittently with >a 10-day washout period...
May 8, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29731878/conversion-of-epithelial-to-mesenchymal-transition-to-mesenchymal-to-epithelial-transition-is-mediated-by-oxygen-concentration-in-pancreatic-cancer-cells
#12
Shuo Chen, Xi Chen, Wei Li, Tao Shan, Wan Run Lin, Jiancang Ma, Xijuan Cui, Wenbin Yang, Gang Cao, Yiming Li, Li Wang, Ya'an Kang
Tumor metastasis is accompanied by a two-stage process of epithelial-to-mesenchymal transition (EMT) and mesenchymal-to-epithelial transition (MET). Currently, the exact mechanisms underlying EMT-MET conversion are unclear. In the present study, the mechanisms by which primary sites (hypoxic) and homing sites (normoxic or hyperoxic) participate in EMT-MET conversion were evaluated. Pancreatic cancer cells were grown under different oxygenation conditions. Cell morphology and epithelial (E)-cadherin and vimentin expression were examined...
May 2018: Oncology Letters
https://www.readbyqxmd.com/read/29720916/evaluation-of-timing-and-dosing-of-caffeine-citrate-in-preterm-neonates-for-the-prevention-of-bronchopulmonary-dysplasia
#13
Eleni E Shenk, Deborah S Bondi, Matthew M Pellerite, Sudhir Sriram
OBJECTIVE: The aim of this study was to evaluate the timing and dosing of caffeine therapy in relation to the development of bronchopulmonary dysplasia (BPD). METHODS: This was a single-center, retrospective cohort study comparing early (days of life 0-2) to late (day of life 3 or greater) caffeine initiation in extremely low birth weight neonates, with a secondary analysis of large (10 mg/kg/day) to small dose (5 mg/kg/day) caffeine. RESULTS: There were 138 patients in the primary timing analysis...
March 2018: Journal of Pediatric Pharmacology and Therapeutics: JPPT: the Official Journal of PPAG
https://www.readbyqxmd.com/read/29717414/primary-central-sleep-apnea-and-anesthesia-a-retrospective-case-series
#14
Alexandru Alexa, Meghna P Mansukhani, Bhargavi Gali, Atousa Deljou, Juraj Sprung, Toby N Weingarten
PURPOSE: Primary (idiopathic) central sleep apnea (PCSA) is a rare central sleep-related breathing disorder characterized by increased chemoreceptor sensitivity to partial pressure of carbon dioxide, which manifests as hyperventilation followed by apnea during non-rapid eye movement sleep. The purpose of this retrospective study was to describe the postoperative course of patients who had PCSA and underwent procedures requiring anesthetic management. METHODS: Patients who received a diagnosis of PCSA at our institution and required procedural anesthesia between 1 January 2010 and 1 June 2016 underwent a comprehensive review of their health records with a focus on identifying respiratory complications...
May 1, 2018: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/29713051/difficult-to-control-hypertension-identification-of-clinical-predictors-and-use-of-ict-based-integrated-care-to-facilitate-blood-pressure-control
#15
Valeria Visco, Rosa Finelli, Antonietta Valeria Pascale, Pietro Mazzeo, Nicola Ragosa, Valentina Trimarco, Maddalena Illario, Michele Ciccarelli, Guido Iaccarino
Difficult-to-control (DTC) hypertension represents a burden in real life that can be partially solved through identification of the characteristics of clinical patterns and tailoring antihypertensive strategies, including ICT-enabled integrated care (ICT-IC). In the quest for clinical predictors of DTC hypertension, we screened 482 hypertensive patients who were consecutively referred to the departmental hypertension clinic. Following a data quality check, patients were divided into controlled (C, 49.37%) and uncontrolled (UC, 50...
May 1, 2018: Journal of Human Hypertension
https://www.readbyqxmd.com/read/29707971/human-multilineage-differentiating-stress-enduring-cells-exert-pleiotropic-effects-to-ameliorate-acute-lung-ischemia-reperfusion-injury-in-a-rat-model
#16
Hiroshi Yabuki, Shohei Wakao, Yoshihiro Kushida, Mari Dezawa, Yoshinori Okada
Posttransplantation lung ischemia-reperfusion (IR) injuries affect both patient survival and graft function. In this study, we evaluated the protective effects of infused human multilineage-differentiating stress-enduring (Muse) cells, a novel, easily harvested type of nontumorigenic endogenous reparative stem cell, against acute IR lung injury in a rat model. After a 2-h warm IR injury induction in a left rat lung, human Muse cells, human mesenchymal stem cells (MSCs), and vehicle were injected via the left pulmonary artery after reperfusion...
January 1, 2018: Cell Transplantation
https://www.readbyqxmd.com/read/29707586/the-relationship-between-diabetes-related-complications-and-obstructive-sleep-apnea-in-type-2-diabetes
#17
Nantaporn Siwasaranond, Hataikarn Nimitphong, Areesa Manodpitipong, Sunee Saetung, Naricha Chirakalwasan, Ammarin Thakkinstian, Sirimon Reutrakul
This study explored the relationship between obstructive sleep apnea (OSA) and the presence of any diabetes-related complications in type 2 diabetes and whether this was mediated by hypertension. Secondly, the relationship between OSA severity and estimated glomerular filtration rate (eGFR) was investigated. A total of 131 patients participated. OSA was diagnosed using a home monitor, and severity was measured by apnea-hypopnea index (AHI) and oxygen desaturation index (ODI). OSA was found in 75.6% of the participants, 40...
2018: Journal of Diabetes Research
https://www.readbyqxmd.com/read/29704781/platinum-69-cobalt-31-alloyed-nanosheet-nanoassemblies-as-advanced-bifunctional-electrocatalysts-for-boosting-ethylene-glycol-oxidation-and-oxygen-reduction
#18
Zhuo-Neng Yu, Zheng Zhang, Zhi-Suo Lv, Meng-Ting Liu, Lu Zhang, Ai-Jun Wang, Liu-Ying Jiang, Jiu-Ju Feng
Pt-based bimetallic nanocrystals are feasible to dramatically improve the catalytic performances in fuel cells via morphology- and composition-engineering. Herein, bimetallic platinum69 -cobalt31 nanosheet nanoassemblies (Pt69 Co31 NSNSs) were facilely synthesized through a one-pot co-reduction solvothermal strategy in oleylamine (OAm), using cetyltrimethylammonium chloride (CTAC) and allantoin as the directing agents. The current synthesis highly depended on the critical concentrations of Pt and Co precursors, the combined use of allantoin to OAm as the co-reductant, and the use of proper allantoin concentration...
April 12, 2018: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29702071/incentive-spirometry-after-lung-resection-a-randomized-controlled-trial
#19
Peter Ra Malik, Christine Fahim, Jordyn Vernon, Priya Thomas, Colin Schieman, Christian J Finley, John Agzarian, Yaron Shargall, Forough Farrokhyar, Wael C Hanna
BACKGROUND: Incentive spirometry (IS) is thought to reduce the incidence of postoperative pulmonary complications (PPC) after lung resection. We sought to determine whether the addition of IS to routine physiotherapy following lung resection results in a lower rate of PPC, as compared to physiotherapy alone. METHODS: A single-blind prospective randomized controlled trial was conducted in adults undergoing lung resection. Individuals with previous lung surgery or home oxygen were excluded...
April 24, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29699897/development-of-regional-extracorporeal-life-support-system-the-importance-of-innovative-simulation-training
#20
Mateusz Puślecki, Marcin Ligowski, Marek Dąbrowski, Sebastian Stefaniak, Małgorzata Ładzińska, Aleksander Pawlak, Marcin Zieliński, Łukasz Szarpak, Bartłomiej Perek, Marek Jemielity
BACKGROUND: Despite advances in mechanical ventilation, severe acute respiratory distress syndrome (ARDS) is associated with high morbidity and mortality rates ranging from 30% to 60%. Extracorporeal Membrane Oxygenation (ECMO) can be used as a "bridge to recovery". ECMO is a complex network that provides oxygenation and ventilation and allows the lungs to rest and recover from respiratory failure, while minimizing iatrogenic ventilator-induced lung injury. In the critical care settings, ECMO is shown to improve survival rates and outcomes in patients with severe ARDS...
April 18, 2018: American Journal of Emergency Medicine
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