keyword
MENU ▼
Read by QxMD icon Read
search

007

keyword
https://www.readbyqxmd.com/read/29475036/adamts-6-is-a-predictor-of-poor-prognosis-in-patients-with-esophageal-squamous-cell-carcinoma
#1
Lan Liu, Zhaoting Yang, Weidong Ni, Yanhua Xuan
BACKGROUND: A disintegrin and metalloprotease with thrombospondin motif (ADAMTS) enzymes play important roles in cell functions including adhesion, invasion, migration, and proliferation. ADAMTS-6 is a member of the ADAMTS family; reports of its relationship with esophageal squamous cell carcinoma (ESCC) progression are rare. It is unclear whether ADAMTS-6 could be an independent ESCC biomarker. METHODS: ADAMTS-6 expression was detected by immunohistochemistry (IHC) in 171 paraffin-embedded ESCC specimens; relationships with patients' clinicopathological features and Twist-1 expression were analyzed by the Pearson Chi-square method, respectively...
February 20, 2018: Experimental and Molecular Pathology
https://www.readbyqxmd.com/read/29474844/cardiac-output-in-pre-eclampsia-is-associated-with-the-presence-of-fetal-growth-restriction-not-gestation-at-onset-a-prospective-cohort-study
#2
Jasmine Tay, Lin Foo, Giulia Masini, Phillip R Bennett, Carmel M Mceniery, Ian B Wilkinson, Christoph C Lees
BACKGROUND AND OBJECTIVES: Pre-eclampsia (PE) and fetal growth restriction (FGR) are considered to be placentally-mediated disorders. The clinical manifestations are widely held to relate to gestation age at onset with early- and late-onset PE considered to be phenotypically distinct. Recent studies have reported conflicting findings in relation to cardiovascular function, and in particular cardiac output, in PE and FGR. STUDY DESIGN: We investigated maternal cardiovascular function in relation to clinical subtype in 45 pathological pregnancies (14 'PE only', 16 'FGR only', 15 'PE and FGR') and compared these with 107 healthy person observations...
February 20, 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29474293/predicting-pain-levels-following-vaginal-reconstructive-surgery-who-is-at-highest-risk
#3
Abigail Shatkin-Margolis, Catrina C Crisp, Christopher Morrison, Rachel N Pauls
OBJECTIVES: An ability to anticipate individuals at increased risk of postoperative pain would improve coordination of care and patient satisfaction. We sought to describe predictive factors of postoperative pain following vaginal reconstructive surgery. METHODS: This institutional review board-approved, retrospective study used previously collected data from research performed at 1 center from 2009 to 2015. Eligible trials enrolled subjects undergoing vaginal reconstructive surgery for pelvic organ prolapse...
March 2018: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/29474289/sequence-of-pelvic-examination-affects-patient-reported-pain
#4
Rebecca Rinko, Ian Yu, Emna Bakillah, Lauren Alper, Colleen Delaney, Marisa Su, Melissa Dawson, Edward J Gracely, Kristene E Whitmore
OBJECTIVE: The purpose of this trial is to compare patient-reported pain based on the sequence of the pelvic examination and to assess the relationship between pain during the examination and quality of life, self-esteem, and sexual function. METHODS: A randomized controlled trial of women presenting for annual gynecologic examinations. Women were assigned to either group A: a Q-tip touch test, speculum examination, then bimanual examination or group B: Q-tip touch test, bimanual examination, then speculum examination...
March 2018: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/29474278/operating-room-efficiency-examining-the-impact-of-personnel-handoffs
#5
Julia Geynisman-Tan, Oluwateniola Brown, Margaret Mueller, Katarzyna Bochenska, Sarah Collins, Christina Lewicky-Gaupp, Kimberly Kenton
OBJECTIVES: This study aimed to determine if personnel handoffs or number of learners in the operating room (OR) are associated with longer OR times in women having pelvic organ prolapse surgery. METHODS: A retrospective review of women undergoing prolapse surgery in 2016 was conducted. Demographics; procedure; OR, anesthetic, and surgical time; number of handoffs between anesthesia members, circulators, and surgical technologies; and number of learners were abstracted...
March 2018: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/29474007/predictors-and-moderators-of-relapse-in-children-and-adolescents-with-major-depressive-disorder
#6
Beth D Kennard, Taryn L Mayes, Zohra Chahal, Paul A Nakonezny, Alexandra Moorehead, Graham J Emslie
OBJECTIVE: To identify predictors and moderators of relapse during continuation treatment among depressed youth randomly assigned to fluoxetine or placebo. METHODS: Potential predictors and moderators of relapse that were identified by a literature review were examined in 102 youth (aged 7-18 years), diagnosed with major depressive disorder as defined by DSM-IV criteria, who were considered responders after 12 weeks of fluoxetine treatment (acute phase). This randomized controlled trial was conducted from June 2000 through October 2005...
February 20, 2018: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/29473768/comparison-of-definitive-intent-finely-fractionated-and-palliative-intent-coarsely-fractionated-radiotherapy-as-adjuvant-treatment-of-feline-microscopic-injection-site-sarcoma
#7
Federica Rossi, Laura Marconato, Silvia Sabattini, Simona Cancedda, Paola Laganga, Vito F Leone, Carla Rohrer Bley
Objectives The aim of this retrospective, bi-institutional study was to evaluate the progression-free interval in a cohort of cats with postoperative microscopic injection-site sarcoma (ISS) treated with two different radiotherapy protocols. Methods Included in the study were cats with ISSs undergoing macroscopic surgical removal and subsequent electron beam radiotherapy treatment with either a finely fractionated protocol (48 or 52.8 Gy over 4 weeks delivered in 12 or 16 fractions) or a coarsely fractionated protocol (36 Gy over 3 weeks administered in six fractions)...
February 1, 2018: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/29473384/five-year-prospective-study-on-cardiovascular-events-in-patients-with-erectile-dysfunction-and-hypotestosterone
#8
Rosanna Iacona, Vito Bonomo, Mariaconcetta Di Piazza, Angela Sansone, Manuela Usala, Salvatore Novo, Carlo Pavone
OBJECTIVE: Testosterone levels play a role in cardiac and vascular pathology. In the present study we investigated the prognostic significance of this hormone for cardiovascular outcome, in a 5-year follow-up. MATERIALS AND METHODS: Our cohort included 802 adult subjects, from 40 to 80 years. Patients were excluded if they had a past history of peripheral or coronary artery disease, and revascularization. A blood sample was drawn to valuate testosterone level, and we considered normal testosterone levels 300 ng/dl...
December 31, 2017: Archivio Italiano di Urologia, Andrologia
https://www.readbyqxmd.com/read/29473247/double-blind-placebo-controlled-multicenter-phase-ii-trial-to-evaluate-d-methionine-in-preventing-reducing-oral-mucositis-induced-by-radiation-and-chemotherapy-for-head-and-neck-cancer
#9
Daniel A Hamstra, Kuei C Lee, Avraham Eisbruch, Prasad Sunkara, Sudhir Borgonha, Babu Phillip, Kathleen C M Campbell, Brian D Ross, Alnawaz Rehemtulla
BACKGROUND: The purpose of this study was to test if oral D-methionine (D-met) reduced mucositis during chemoradiotherapy. METHODS: We conducted a placebo-controlled double-blind randomized phase II trial of D-met (100 mg/kg p.o. b.i.d.) testing the rate of severe (grades 3-4) mucositis. RESULTS: Sixty patients were randomized. Grade 2 + oral pain was higher with placebo (79% vs 45%; P = .0165), whereas grade 2 + body odor was greater with D-met (3% vs 41%; P = ...
February 23, 2018: Head & Neck
https://www.readbyqxmd.com/read/29473101/cardiac-function-assessments-in-left-bochdalek-s-hernia-clinical-relevance
#10
Arvind Sehgal, Kenneth Tan, Peter Ferguson
The objectives of this study were to characterize peri-operative echocardiographic (ECHO) assessments of right ventricular (RV) function and pulmonary hypertension (PH) and ascertain correlation with clinical outcomes in infants with left Bochdalek's hernia (LBH). This retrospective study in a quaternary neonatal intensive care unit involved electronic database search for infants with LBH during January 2009 to July 2017. Demographics, outcomes, and ECHO parameters were accessed from archived databases. Thirty-one infants with mean gestational age and birthweight (BW) 38...
February 23, 2018: Pediatric Cardiology
https://www.readbyqxmd.com/read/29472587/association-of-brca1-ercc1-rap80-pkm2-rrm1-rrm2-ts-tsp1-and-txr1-mrna-expression-levels-between-primary-tumors-and-infiltrated-regional-lymph-nodes-in-patients-with-resectable-non-small-cell-lung-cancer
#11
K Tryfonidis, C Papadaki, S Assele, E Lagoudaki, J Menis, A Koutsopoulos, M Trypaki, E Tsakalaki, M Sfakianaki, B Hasan, E Stathopoulos, V Georgoulias, J Souglakos
Differences in gene expression levels between the primary tumors (PTs) and matched regional lymph nodal metastases (LNs) in patients with totally excised non-small cell lung cancer (NSCLC) were explored. Microdissected formalin-fixed paraffin-embedded (FFPE) samples from (PT) and their matched infiltrated LNs, from 239 patients [183 (with matched PT and LNs samples)-case and 56 PT only samples-control cohorts] were analyzed for BRCA1, ERCC1, RAP80, PKM2, RRM1, RRM2, TS, TSP1, and TXR1 mRNA expression by quantitative real-time polymerase-chain reaction (PCR)...
February 22, 2018: Pharmacogenomics Journal
https://www.readbyqxmd.com/read/29471908/prognostic-factors-for-treatment-success-in-patients-with-multidrug-resistant-tuberculosis-in-china
#12
Y-M Fan, S-P Ding, Z-J Bao, L-M Wu, L-B Zhen, Q Xia, M Zhu
OBJECTIVE: To examine the clinical outcomes and associated prognostic factors among patients with multidrug-resistant tuberculosis (MDR-TB) in China. METHODS: This retrospective study involved 243 patients with MDR-TB. All patients received standard regimens containing para-amino salicylic acid (PAS) and/or cycloserine (CS). The demographic, social and clinical characteristics of patients were recorded and the patients were followed up for 24 months. RESULTS: Treatment success was closely associated with young age, non-farming occupations, shorter history or smoking, normal urine results, initial MDR-TB treatment regimen, increased haemoglobin, direct bilirubin, uric acid and thyroid stimulating hormone (TSH) levels, and lower white blood cell, neutrophil and blood platelet counts (all P < 0...
March 1, 2018: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/29471485/trabecular-bone-score-as-an-assessment-tool-to-identify-the-risk-of-osteoporosis-in-axial-spondyloarthritis-a-case-control-study
#13
Kwi Young Kang, Hye Yeon Goo, Sung-Hwan Park, Yeon Sik Hong
Objectives: To compare the trabecular bone score (TBS) between patients with axial spondyloarthritis (axSpA) and matched normal controls and identify risk factors associated with a low TBS. Methods: TBS and BMD were assessed in the two groups (axSpA and control) using DXA. Osteoporosis risk factors and inflammatory markers were also assessed. Disease activity and radiographic progression in the sacroiliac joint and spine were evaluated in the axSpA group. Multivariate linear regression analysis was performed to identify risk factors associated with TBS...
March 1, 2018: Rheumatology
https://www.readbyqxmd.com/read/29471403/influence-of-distiller-s-dried-grains-with-solubles-on-ram-lamb-growth-and-reproductive-traits
#14
A R Crane, R R Redden, M S Crouse, J D Kirsch, P P Borowicz, J E Held, K C Swanson, C S Schauer
The hypothesis of this experiment was that increasing the inclusion level of distiller's dried grains (DDGS) in the diets would decrease semen quality but have no negative effects on growth performance. Following the removal of DDGS from the diet, it was hypothesized that the ram lambs would recover and become reproductively sound, independent of treatment. To test this hypothesis, Suffolk and Hampshire ram lambs (n = 112) were allocated to four treatments (n = 4 pens/treatment; 7 rams/pen) in a completely randomized design...
February 20, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29471165/emission-characteristics-of-pcdd-fs-in-stack-gas-from-municipal-solid-waste-incineration-plants-in-northern-china
#15
Feng Zhu, Xiaofei Li, Jia-Wei Lu, Jing Hai, Jieru Zhang, Bing Xie, Chengyang Hong
Emission characteristics including congener's profile, gas emissions and toxic equivalent concentration (TEQ) indicators of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) in 57 stack gas samples from 6 municipal solid waste incinerators (MSWIs) in Northern China were investigated by gas chromatography-high resolution mass spectrometry (HRGC-HRMS). Additionally, PCDD/Fs formation mechanisms from the MSWIs were briefly discussed. Results revealed that the concentrations and equivalent concentrations of PCDD/Fs emissions in stack gas from 6 MSWIs were in the range of 0...
February 16, 2018: Chemosphere
https://www.readbyqxmd.com/read/29470363/a-physiological-and-sport-specific-comparison-between-division-i-and-division-ii-italian-male-field-hockey-players
#16
Sandro Bartolomei, Federico Nigro, Luca Gubellini, Simone Ciacci, Franco Merni, Filippo Treno, Matteo Cortesi, Gabriele Semprini
The purpose of the present study was to compare the anthropometric and performance profiles of division I (D1) and division II (D2) Italian field hockey players.Fifteen DI players and fifteen D2 players (age = 25.4 ± 5.2 y; body mass = 78.5 ± 9.0 kg; body height = 179.6 ± 7.8 cm) were assessed on one occasion for anthropometry, body composition, physiological measurements and sport-specific skills. Differences between the two groups were evaluated using a one-way analysis of variance. Pearson correlations were used to examine relationships between the different measurements...
February 20, 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29469443/-studies-on-resistance-of-schistosoma-to-praziquantel-xvii-biological-characteristics-of-praziquantel-resistant-isolates-of-schistosoma-japonicum-in-mice
#17
Qian Ke, Liang You-Sheng, Wang Wei, Qu Guo-Li, Li Hong-Jun, Yang Zhen-Kun, Zhao Zheng-Yang, Xing Yuntian, Dai Jian-Rong
OBJECTIVE: To investigate the biological characteristics of the praziquantel-resistant isolate of Schistosoma japonicum in mice, so as to explore the pathogenicity to definitive hosts and transmission intensity of the praziquantel-resistant isolate of S. japonicum . METHODS: Mice were infected with the cercariae released from two praziquantel-resistant isolates and two praziquantel-susceptible isolates of S. japonicum . The mouse- Oncomelania hupensis snail-mouse cycle was established and maintained in the laboratory...
December 26, 2017: Zhongguo Xue Xi Chong Bing Fang Zhi za Zhi, Chinese Journal of Schistosomiasis Control
https://www.readbyqxmd.com/read/29469181/lymphocyte-immunotherapy-for-recurrent-miscarriages-predictors-of-therapeutic-success
#18
Marcelo Borges Cavalcante, Manoel Sarno, Marla Niag, Kleber Pimentel, Ivana Luz, Bianca Figueiredo, Tatiana Michelon, Simone Lima, Isabela Nelly Machado, Edward Araujo Júnior, Ricardo Barini
PROBLEM: To evaluate the predictors of successful pregnancies in women with a history of recurrent miscarriages (RMs) having undergone lymphocyte immunotherapy (LIT). METHOD OF STUDY: Retrospective, multicenter, observational study which involved 702 pregnant women with history of RM treated with LIT. Comparative analysis of women with a history of RM having undergone LIT and experienced treatment success vs those having experienced treatment failure along with the analysis of the association between the number of prior miscarriages and the efficacy of LIT...
February 22, 2018: American Journal of Reproductive Immunology: AJRI
https://www.readbyqxmd.com/read/29469177/haemodynamic-effects-of-levosimendan-in-advanced-but-stable-chronic-heart-failure
#19
Emil Najjar, Marcus Stålhberg, Camilla Hage, Erica Ottenblad, Aristomenis Manouras, Ida Haugen Löfman, Lars H Lund
AIMS: Levosimendan improves haemodynamics in acute decompensated heart failure (HF). However, it is increasingly used for repetitive or intermittent infusions in advanced but stable chronic HF, without clear indication, selection criteria, or effect. We tested the hypotheses that (1) levosimendan improves haemodynamics in stable chronic HF and (2) that the response is dependent on baseline clinical and haemodynamic factors. METHODS AND RESULTS: Twenty-three patients [median age 56 (49-64) years, four (17%) women] with stable New York Heart Association (NYHA) III and IV HF received a single 24 h levosimendan infusion...
February 22, 2018: ESC Heart Failure
https://www.readbyqxmd.com/read/29468763/medical-marijuana-laws-and-adolescent-marijuana-use-in-the-united-states-a-systematic-review-and-meta-analysis
#20
REVIEW
Aaron L Sarvet, Melanie M Wall, David S Fink, Emily Greene, Aline Le, Anne E Boustead, Rosalie Liccardo Pacula, Katherine M Keyes, Magdalena Cerdá, Sandro Galea, Deborah S Hasin
AIMS: To conduct a systematic review and meta-analysis of studies in order to estimate the effect of US medical marijuana laws (MMLs) on past-month marijuana use prevalence among adolescents. METHODS: A total of 2999 papers from 17 literature sources were screened systematically. Eleven studies, developed from four ongoing large national surveys, were meta-analyzed. Estimates of MML effects on any past-month marijuana use prevalence from included studies were obtained from comparisons of pre-post MML changes in MML states to changes in non-MML states over comparable time-periods...
February 22, 2018: Addiction
keyword
keyword
12590
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"