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Endocrine surgery

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https://www.readbyqxmd.com/read/29690864/radiogenic-angiosarcoma-of-the-breast-case-report-and-systematic-review-of-the-literature
#1
Askin Dogan, Peter Kern, Beate Schultheis, Günther Häusler, Günther A Rezniczek, Clemens B Tempfer
BACKGROUND: Radiogenic angiosarcoma of the breast (RASB) is a rare late sequela of local irradiation of the breast or chest wall after breast cancer. The prognosis of women with RASB is poor and there is no standardized therapy for this type of malignancy. CASE PRESENTATION: We present the case of a 54 year old woman with RASB (poorly differentiated angiosarcoma of the left breast; pT1, pNX, M0, L0, V0) and a history of invasive-ductal cancer of the left breast (pT1b, G2, pN0, ER positive, PR positive, HER-2/neu negative) treated in July 2012 with breast-conserving surgery, adjuvant chemotherapy with 6 cycles of epirubicin and cyclophosphamide, adjuvant irradiation of the left breast with 50 Gray, and adjuvant endocrine therapy with an aromatase inhibitor...
April 24, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29688761/community-endocrine-surgical-experience-with-false-negative-afirma-gec-%C3%A2-results-2011-2017
#2
R Mack Harrell, Stephanie A Eyerly-Webb, Nat E Pinnar, Allan C Golding, Courtney M Edwards, David N Bimston
OBJECTIVE: Afirma Gene Expression Classifier® (Afirma GEC® ) molecular analysis (Veracyte, Inc.; San Francisco, CA) is a negative predictive value (NPV) test developed to reduce the number of thyroidectomies in thyroid nodule patients with indeterminate cytology. GEC technology has reportedly reduced unnecessary thyroid surgery, but few studies have examined Afirma GEC false negative rates since usually patients with GEC benign nodules do not undergo surgery for definitive diagnosis...
April 24, 2018: Endocrine Practice
https://www.readbyqxmd.com/read/29687661/clinicopathologic-features-of-hormone-receptor-positive-breast-cancer-patients-with-late-recurrence
#3
Takeshi Murata, Hiromitsu Jinno, Maiko Takahashi, Masayuki Shimoda, Tetsu Hayashida, Kaori Kameyama, Yuko Kitagawa
The number of long-term breast cancer survivors with a risk of late recurrence is increasing. Hormone-receptor-positive patients have greater risks of late recurrence. Although several studies demonstrated that extended adjuvant endocrine therapy reduces the incidence of late recurrence, it remains unclear which hormone-receptor-positive patients have greater risks of late recurrence. Hormone-receptor-positive breast cancer patients were retrospectively selected from the prospective database of primary breast cancer patients treated at Keio University Hospital from January 1989 to December 2003...
April 23, 2018: Breast Journal
https://www.readbyqxmd.com/read/29679334/metabolic-surgery-and-diabesity-a-systematic-review
#4
REVIEW
Lionel El Khoury, Elie Chouillard, Elias Chahine, Elias Saikaly, Tarek Debs, Radwan Kassir
Bariatric surgery is used to induce weight loss (baros = weight). Evidence has shown that bariatric surgery improves the comorbid conditions associated with obesity such as hypertension, hyperlipidemia, and type 2 diabetes mellitus T2DM. Hence, shifting towards using metabolic surgery instead of bariatric surgery is currently more appropriate in certain subset of patients. Endocrine changes resulting from operative manipulation of the gastrointestinal tract after metabolic surgery translate into metabolic benefits with respect to the comorbid conditions...
April 20, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29677569/validation-of-the-ajcc-8th-prognostic-system-for-breast-cancer-in-an-asian-healthcare-setting
#5
R X Wong, F Y Wong, John Lim, W X Lian, Y S Yap
AIMS: We aim to validate the AJCC 8th edition prognostic staging system for breast cancer in an Asian setting. METHODS: Clinico-pathologic information and cancer-specific survival (CSS) outcomes of 6287 stage I to III patients with invasive breast cancer who underwent upfront surgery at SingHealth institutions in Singapore from 2006 to 2014 were analyzed. Survival distributions for the different staging systems were estimated by the Kaplan-Meier method and compared using the log-rank tests...
April 17, 2018: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/29676711/-intraoperative-neuromonitoring-in-endocrine-surgery-when-is-it-appropriate
#6
A F Engelsman, E J M Nieveen van Dijkum
The use of intraoperative neuromonitoring (IONM) in thyroid surgery has steadily increased in recent years. This technique helps to identify different nerves in and around the operation site, such as the recurrent laryngeal nerve (RLN) and the external branch of the superior laryngeal nerve. Particularly in patients who undergo a second operation or a complex procedure for malignancy, the technique's value has been demonstrated. However, in non-complex thyroid operations the risk of vocal cord paresis due to iatrogenic injury of the RLN is 0...
2018: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/29675407/pancreatic-aquaporin-7-a-novel-target-for-anti-diabetic-drugs
#7
REVIEW
Leire Méndez-Giménez, Silvia Ezquerro, Inês V da Silva, Graça Soveral, Gema Frühbeck, Amaia Rodríguez
Aquaporins comprise a family of 13 members of water channels (AQP0-12) that facilitate a rapid transport of water across cell membranes. In some cases, these pores are also permeated by small solutes, particularly glycerol, urea or nitric oxide, among other solutes. Several aquaporins have been identified in the pancreas, an exocrine and endocrine organ that plays an essential role in the onset of insulin resistance and type 2 diabetes. The exocrine pancreas, which accounts for 90% of the total pancreas, secretes daily large volumes of a near-isotonic fluid containing digestive enzymes into the duodenum...
2018: Frontiers in Chemistry
https://www.readbyqxmd.com/read/29675258/livedo-reticularis-a-cutaneous-clue-to-an-underlying-endocrine-crisis
#8
Natasha Shrikrishnapalasuriyar, Mirena Noyvirt, Philip Evans, Bethan Gibson, Elin Foden, Atul Kalhan
A 54-year-old woman was admitted to hospital with a presumed allergic reaction to a single dose of amoxicillin given for a suspected upper respiratory tract infection. She complained of chest tightness although there was no wheeze or stridor. On examination, she was pyrexial, tachycardic, hypertensive and had a diffuse mottled rash on her lower limbs. Her initial investigations showed raised inflammatory markers. She was treated in the intensive care for a presumed anaphylactic reaction with an underlying sepsis...
2018: Endocrinology, Diabetes & Metabolism Case Reports
https://www.readbyqxmd.com/read/29673111/comparison-of-epidemiological-features-clinicopathological-features-and-treatments-between-premenopausal-and-postmenopausal-female-breast-cancer-patients-in-western-china-a-retrospective-multicenter-study-of-15-389-female-patients
#9
REVIEW
Fan Feng, Yuxian Wei, Ke Zheng, Yujing Li, Lu Zhang, Tielin Wang, Yanli Zhang, Hongyuan Li, Guosheng Ren, Fan Li
Premenopausal and postmenopausal breast cancers are considered different types. Thus, this study aimed to explore differences in risk factors, epidemiological features, clinicopathological features, and treatment modes of premenopausal breast cancer compared to postmenopausal patients in western China. This was a hospital-based, retrospective, multicenter epidemiological study of patients with breast cancer. Using the Western China Clinical Cooperation Group database, we obtained the records of 15,389 female breast cancers between January 2010 and April 2017...
April 19, 2018: Cancer Medicine
https://www.readbyqxmd.com/read/29671537/chronic-pancreatitis-diagnosis-and-treatment
#10
Kathleen Barry
Chronic pancreatitis is an irreversible and progressive disorder of the pancreas characterized by inflammation, fibrosis, and scarring. Exocrine and endocrine functions are lost, often leading to chronic pain. The etiology is multifactorial, although alcoholism is the most significant risk factor in adults. The average age at diagnosis is 35 to 55 years. If chronic pancreatitis is suspected, contrast-enhanced computed tomography is the best imaging modality for diagnosis. Computed tomography may be inconclusive in early stages of the disease, so other modalities such as magnetic resonance imaging, magnetic resonance cholangiopancreatography, or endoscopic ultrasonography with or without biopsy may be used...
March 15, 2018: American Family Physician
https://www.readbyqxmd.com/read/29663329/prophylactic-thyroidectomy-in-children-with-multiple-endocrine-neoplasia-type-2
#11
F P Prete, T Abdel-Aziz, C Morkane, C Brain, T R Kurzawinski
BACKGROUND: In patients with multiple endocrine neoplasia type 2 (MEN2) syndrome, genetic testing offers early diagnosis, stratifies the risk of developing medullary thyroid cancer (MTC) and informs the timing of thyroidectomy. The efficacy of treatment, which depends on timely and safe surgery, is not well established. METHODS: This was a retrospective review of diagnostic and clinicopathological outcomes of prophylactic thyroidectomy in children with MEN2 between 1995 and 2013 in the UK...
April 17, 2018: British Journal of Surgery
https://www.readbyqxmd.com/read/29660423/cme-part-2-hair-disorders-in-cancer-survivors-persistent-chemotherapy-induced-alopecia-persistent-radiotherapy-induced-alopecia-and-hair-growth-disorders-related-to-endocrine-therapy-or-cancer-surgery
#12
REVIEW
Azael Freites-Martinez, Jerry Shapiro, Corina van den Hurk, Shari Goldfarb, Joaquin Jimenez, Anthony M Rossi, Ralf Paus, Mario E Lacouture
With increasing survival rates across all cancers, survivors represent a growing population that is frequently affected by persistent or permanent hair growth disorders as a result of systemic therapies, radiotherapy, surgical procedures, and therapeutic transplants. These hair disorders include persistent chemotherapy-induced alopecia, persistent radiotherapy-induced alopecia, endocrine therapy-induced alopecia and hirsutism, post-surgery alopecia and localized hypertrichosis, alopecia attributed to therapeutic transplants, and to novel anticancer therapies...
April 13, 2018: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29650835/-diagnosis-of-a-non-invasive-ductal-carcinoma-assisted-by-long-term-follow-up-of-spontaneous-nipple-discharge-a-case-report
#13
Tomohiro Hirano, Shuhei Suzuki, Keita Adachi, Hitomi Kubota, Yukiko Hara, Katsuhisa Enomoto, Ryouichi Tomita, Shigeru Fujisaki, Kenichi Sakurai
We report a case of a non-invasive ductal carcinoma revealed on long-term follow-up of spontaneous nipple discharge. The patient, a 36-year-old woman, had noticed spontaneous nipple discharge from both breasts over a 3-year period. Mammography and ultrasonography did not reveal any lesions in the breasts. The nipple discharge from her left breast stopped 36 months after initial clinical assessment. However, the nipple discharges from her right breast transformed into a bloody discharge from a single duct. Ultrasonography showed a tumor, 6mm in diameter, in the upper-outer quadrant of her right breast...
April 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29650825/-successful-breast-conserving-surgery-for-simultaneous-and-ipsilateral-multiple-breast-carcinomas-of-young-patient-a-case-report
#14
Hitomi Kubota, Keita Adachi, Shuhei Suzuki, Shigeru Fujisaki, Yukiko Hara, Katsuhisa Enomoto, Ryouichi Tomita, Tomohiro Hirano, Kenichi Sakurai
We report a case of a simultaneous and ipsilateral multiple breast carcinoma.The patient was 35-year-old woman.She was noticed a breast lump on her right breast, and visited our hospital.Mammography showed a tumor accompanied by spiculation on her right breast.Ultrasonography revealed 2 tumors with irregular margins, 23mm in diameter and 12mm in diameter, and were observed on C area of her right breast.The continuity of the 2 tumors was not clear.Core needle biopsies for each breast tumors led to a diagnosis...
April 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29650819/-a-case-report-of-neuroendocrine-carcinoma-in-the-gall-bladder-showing-recurrence-shortly-after-surgery
#15
Yoshihiro Uchino, Sonofu Taketani, Nobuhisa Hirayu, Koji Shiota, Hironobu Sou, Satoshi Taniwaki, Tetsuo Imamura
A55 -year-old woman with a 10×8mm protuberant gallbladder lesion visited our hospital. To determine possible malignancy, she underwent laparoscopic excision biopsy of the gallbladder, and pathological findings revealed an endocrine carcinoma in the gallbladder. Surgery involved extrahepatic bile duct resection, gallbladder bed resection, and hepatic portal lymph node resection. Recurrence in the peritoneal lymph node was observed in the early postoperative period. Chemotherapy was initiated with cisplatin and irinotecan, and continues 18 months post-operatively...
April 2018: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29629315/surgical-resection-of-neuroendocrine-tumors-of-the-pancreas-pnets-by-minimally-invasive-surgery-the-laparoscopic-approach
#16
REVIEW
Tomoki Shirota, Yuichi Nagakawa, Yatsuka Sahara, Chie Takishita, Yosuke Hijikata, Yuichi Hosokawa, Tetsushi Nakajima, Hiroaki Osakabe, Kenji Katsumata, Akihiko Tsuchida
Neuroendocrine tumors of the pancreas (pNETs) are a rare group of neoplasms that originate from the endocrine portion of the pancreas. Tumors that either secrete or do not secrete compounds, resulting in symptoms, can be classified as functioning and non-functioning pNETs, respectively. The prevalence of such tumors has recently increased due to the use of more sensitive imaging techniques, such as multidetector computed tomography, magnetic resonance imaging and endoscopic ultrasound. The biological behavior of pNETs varies widely from indolent, well-differentiated tumors to those that are far more aggressive...
February 2018: Gland Surgery
https://www.readbyqxmd.com/read/29628632/expression-of-bax-and-bcl2-genes-in-peripheral-blood-lymphocytes-of-patients-with-differentiated-thyroid-cancer
#17
Zari Hamivand, Gholamhassan Haddadi, Reza Fardid
Context: Thyroid cancer is the most common endocrine malignancy worldwide. Iodine-131 is used in the treatment of thyroid cancer with dosage of 100 mCi. In the medical applications of ionizing radiation besides the advantages such as diagnosis and treatment of diseases, the risks arising from exposure should be considered as well. Aims: The present study aimed to evaluate the changes in expression levels of apoptotic Bax and Bcl-2 and the ratio of Bax/Bcl-2, in the peripheral blood lymphocytes (PBLs) of patients with differentiated thyroid cancer (DTC)...
January 2018: Journal of Medical Physics
https://www.readbyqxmd.com/read/29625700/quality-of-life-in-cushing-s-disease-a-long-term-issue
#18
Susan M Webb, Alicia Santos, Eugenia Resmini, Maria-Antonia Martínez-Momblán, Luciana Martel, Elena Valassi
The purpose of this review is to describe how quality of life (QoL) is impaired in patients with hypercortisolism due to Cushing's syndrome of any aetiology, including pituitary-dependent Cushing's disease. It is worse in active disease, but improvement after successful therapy is often incomplete, due to persistent physical and psychological co-morbidities, even years after endocrine "cure". Physical symptoms like extreme fatigability, central obesity with limb atrophy, hypertension, fractures, and different skin abnormalities severely impair the affected patients' everyday life...
April 3, 2018: Annales D'endocrinologie
https://www.readbyqxmd.com/read/29607749/a-home-for-endocrine-surgery-research
#19
Michael C Singer
No abstract text is available yet for this article.
April 2018: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29607686/use-of-integrative-oncology-involvement-in-decision-making-and-breast-cancer-survivor-health-related-quality-of-life-in-the-first-5-years-postdiagnosis
#20
M Robyn Andersen, Erin Sweet, Shelly Hager, Marcia Gaul, Fred Dowd, Leanna J Standish
OBJECTIVE: This study sought to describe changes in the health-related quality of life (HRQOL) of women who do and do not seek naturopathic oncology (NO) complementary and alternative medicine (CAM) care during and immediately after breast cancer treatment, and to explore the predictive role of NO CAM care, demographic characteristics, and involvement in decision-making on HRQOL in breast cancer survivors. METHODS: Matched cohorts of breast cancer survivors who did and did not choose to supplement their breast cancer treatment with NO care within 2 years of diagnosis participated...
March 1, 2018: Integrative Cancer Therapies
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