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https://www.readbyqxmd.com/read/28812878/nanomechanical-imaging-of-the-diffusion-of-fullerene-into-conjugated-polymer
#1
Dong Wang, Ken Nakajima, Feng Liu, Shaowei Shi, Thomas P Russell
The large Young's modulus difference between chemically modified fullerene (PCBM) and a conjugated polymer was used to nanomechanically map the diffusion of PCBM into PTB7, a high efficiency low band gap conjugated polymer. The sharp tip in nanomechanical atomic force microscopy (AFM) ensures a high-resolution nanomechanical characterization of the diffusion front, with the intrinsic benefits of revealing the mechanical properties of the mixtures. Localized structure changes induced by diffusion were investigated by grazing incidence x-ray diffraction methods...
August 16, 2017: ACS Nano
https://www.readbyqxmd.com/read/28812321/prognostic-impact-of-intensive-statin-therapy-on-n-terminal-pro-bnp-level-in-non-st-segment-elevation-acute-myocardial-infarction-patients
#2
Mohamed Shehata, Ayman Samir, May Dardiri
OBJECTIVE: This study explored the impact of intensive daily dosing of atorvastatin on in-hospital N-terminal pro-B-type natriuretic peptide level, left ventricular systolic function and incidence of major adverse cardiac events in non-ST-segment elevation myocardial infarction patients. BACKGROUND: Several studies showed that early initiation of statin therapy in acute coronary syndrome patients has a favorable prognostic impact. METHODS: Hundred statin naive patients were prospectively enrolled...
August 15, 2017: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/28812052/the-superior-labial-frenulum-in-newborns-what-is-normal
#3
Chloe Santa Maria, Janelle Aby, Mai Thy Trong, Yogita Thakur, Sharon Rea, Anna Messner
Introduction and Objectives: There has been an emergence of procedures to release the superior labial frenula in infants, yet little is known about the normal appearance or incidence of severe attachment, or "lip-tie." The objective of this article was to develop a classification system for superior labial frenula and to estimate the incidence of different degrees of attachment. Methods: A prospective cross-sectional study. Newborns were examined and had photographs taken of their upper frenula. Relevant medical professionals rated the appearance of the labial frenula using a previously described Kotlow classification system...
2017: Global Pediatric Health
https://www.readbyqxmd.com/read/28812046/extra-virgin-olive-oil-ameliorates-cognition-and-neuropathology-of-the-3xtg-mice-role-of-autophagy
#4
Elisabetta Lauretti, Luigi Iuliano, Domenico Praticò
OBJECTIVE: Consumption of extra virgin olive oil (EVOO), a major component of the Mediterranean diet, has been associated with reduced incidence of Alzheimer's disease (AD). However, the mechanisms involved in this protective action remain to be fully elucidated. METHODS: Herein, we investigated the effect of daily consumption of EVOO on the AD-like phenotype of a mouse mode of the disease with plaques and tangles. RESULTS: Triple transgenic mice (3xTg) received either regular chow or a chow diet supplemented with EVOO starting at 6 months of age for 6 months, then assessed for the effect of the diet on the AD-like neuropathology and behavioral changes...
August 2017: Annals of Clinical and Translational Neurology
https://www.readbyqxmd.com/read/28812031/early-single-sport-specialization-a-survey-of-3090-high-school-collegiate-and-professional-athletes
#5
Patrick S Buckley, Meghan Bishop, Patrick Kane, Michael C Ciccotti, Stephen Selverian, Dominique Exume, William Emper, Kevin B Freedman, Sommer Hammoud, Steven B Cohen, Michael G Ciccotti
BACKGROUND: Youth participation in organized sports in the United States is rising, with many athletes focusing on a single sport at an increasingly younger age. PURPOSE: To retrospectively compare single-sport specialization in current high school (HS), collegiate, and professional athletes with regard to the rate and age of specialization, the number of months per year of single-sport training, and the athlete's perception of injury related to specialization. STUDY DESIGN: Cross-sectional study; Level of evidence, 3...
July 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28812012/spinal-cord-injury-due-to-tumour-or-metastasis-in-arag%C3%A3-n-northeastern-spain-1991-2008-incidence-time-trends-and-neurological-function
#6
Maayken Elizabeth Louise van den Berg, Juan M Castellote, Jose Ignacio Mayordomo, Ignacio Mahillo-Fernandez, Jesus de Pedro-Cuesta
PURPOSE: Understanding the presentation of spinal cord injury (SCI) due to tumours considering population distribution and temporal trends is key to managing SCI health services. This study quantified incidence rates, function scores, and trends of SCI due to tumour or metastasis over an 18-year time period in a defined region in Spain. METHODS: A retrospective cohort study included in-and outpatients with nontraumatic SCI due to tumour or metastasis admitted to a metropolitan hospital in Spain between 1991 and 2008...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28811901/perioperative-safety-analysis-of-transcatheter-arterial-chemoembolization-for-hepatocellular-carcinoma-patients-with-preprocedural-leukopenia-or-thrombocytopenia
#7
Lin Zhou, Lin-Zhi Zhang, Jing-Yan Wang, Yong-Wu Li, Hai-Dong Hu, Xiao-Ming Peng, Yun Zhao, Xi-Ming Wang, Hui Xie, Chun-Zi Liu, Hua-Ming Wang
Patients with hepatocellular carcinoma (HCC) exhibit a high incidence of concomitant cirrhosis with leukopenia and/or thrombocytopenia. In the present study, perioperative changes in the white blood cell (WBC) and platelet (PLT) counts and associated complications were investigated to assess the safety of transcatheter arterial chemoembolization (TACE) for HCC patients with preprocedural leukopenia or thrombocytopenia. The records of 1,461 HCC patients who received TACE between January 2012 and December 2013 were retrospectively reviewed...
September 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28811871/do-all-patients-with-atrial-fibrillation-need-long-term-anticoagulation
#8
Munish Sharma, Rohit Masih, Daniel A N Mascarenhas
Atrial fibrillation (AF) is the most common cardiac arrhythmia worldwide with an estimated number of 2.7-6.1 million cases in the United States (US) alone. The incidence of AF is expected to increase 2.5 fold over the next 50 years in the US. The management of AF is complex and includes mainly three aspects; restoration of sinus rhythm, control of ventricular rate and prevention of systemic thromboembolism. AF as a cause of systemic embolization has been well known for many years, and majority of patients are on oral anticoagulants (OACs) to prevent this...
June 7, 2017: Clinics and Practice
https://www.readbyqxmd.com/read/28811851/epidemiology-of-infective-endocarditis-in-rural-upstate-new-york-2011-2016
#9
Saeeda Fatima, Benajmin Dao, Ayesha Jameel, Konika Sharma, David Strogatz, Melissa Scribani, Harish Raj Seetha Rammohan
BACKGROUND: The epidemiology of infective endocarditis (IE) depends on a number of host factors whose prevalence can vary globally. The usual patient population affected by IE is sicker and older, often with many comorbid conditions. The risk is growing in younger populations due to the emerging epidemic of intravenous (IV) drug use. We have performed a temporal trend analysis of various factors of IE in the rural counties covering a major part of central Upstate New York. METHODS: We performed a retrospective analysis of electronic medical records of patients who were admitted in a tertiary care hospital in rural Upstate New York and diagnosed with IE from January 1, 2011 to December 31, 2016...
September 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28811761/incidence-rates-of-major-diseases-of-kiwiberry-in-2015-and-2016
#10
Gyoung Hee Kim, Deok Ryong Kim, Sook-Young Park, Young Sun Lee, Jae Sung Jung, Young Jin Koh
Incidence rates of diseases in kiwiberry orchards were investigated monthly from late June to late September in Gwangyang and Boseong in 2015 and 2016. The impact of postharvest fruit rot was investigated during ripening after harvest. Bacterial canker was only observed on one single tree in 2015, but black rot, powdery mildew, leaf spot and blight, and postharvest fruit rot diseases were problematic throughout the study period in both 2015 and 2016. Incidence rates of the diseases varied with kiwiberry cultivar, region and sampling time...
August 2017: Plant Pathology Journal
https://www.readbyqxmd.com/read/28810873/six-month-adherence-to-statin-use-and-subsequent-risk-of-major-adverse-cardiovascular-events-mace-in-patients-discharged-with-acute-coronary-syndromes
#11
Gaoqiang Xie, Yihong Sun, Phyo Kyaw Myint, Anushka Patel, Xingzi Yang, Min Li, Xian Li, Tao Wu, Shenshen Li, Runlin Gao, Yangfeng Wu
BACKGROUND: The evidence of adherence to statin decreasing risk of major adverse cardiovascular events (MACEs) is still lack among patients discharged with acute coronary syndrome (ACS). Our objective is to determine the relationship between six-month adherence to statins and subsequent risk of MACEs in patients discharged with ACS. METHODS: Using two prospective registry cohorts (CPACS-1 and -2), we analyzed data from 12,516 consecutive patients with ACS who were prescribed statin at hospital discharge and survived beyond 6 months without recurrent myocardial infarction (MI) or stroke...
August 15, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/28809867/-risk-perception-and-biological-parameters-related-to-obesity-in-a-sample-population-of-the-city-of-rome-italy-nurses-contribution-to-supporting-health-related-decisions
#12
Eduardo Mazza, Daniele I La Milia, Caterina Galletti, Stefano Gambioli, Umberto Moscato, Gianfranco Damiani, Patrizia Laurenti
INTRODUCTION: Obesity is a major public health problem because it is a risk factor for various chronic diseases and its incidence is constantly increasing due to changes in diet and lifestyle. In Italy, studies show that 32% of the population aged between 18 and 69 years is overweight and 10% is obese. The aim of this study was to measure the anthropometric characteristics of a sample population of the city of Rome (Italy) and correlate these with dietary habits and socio-demographic characteristics of participants in order to evaluate their specific health and educational needs...
May 2017: Igiene e Sanità Pubblica
https://www.readbyqxmd.com/read/28809627/-the-use-of-btb-allograft-in-revision-reconstruction-of-the-anterior-cruciate-ligament-and-its-success-rate-in-terms-of-subjective-patient-satisfaction
#13
J Sklenský, P Vališ, M Repko, M Rouchal, M Maršálek, D Hrůzová
PURPOSE OF THE STUDY A retrospective evaluation of the success rate of revision ACL reconstruction performed using BTB allograft in terms of the life expectancy of the procedure up to and over five years from surgery. MATERIAL AND METHODS Over a ten-year period, from 2003 to 2013, we performed 47 revision ACL reconstruction surgeries. The majority of the primary ACL reconstructions using BTB autografts were not performed at our site. The group observed included 16 women (34%) and 31 men (66%). The women were aged between 25 and 48 years, the median age being 32...
2017: Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca
https://www.readbyqxmd.com/read/28809622/suicide-in-pretoria-a-retrospective-review-2007-2010
#14
Cornelia Engelbrecht, Ryan Blumenthal, Neil K Morris, Gert Saayman
BACKGROUND: The World Health Organization has declared suicide a global ealth crisis, predicting that ~1.53 million people will commit suicide annually by 2020. OBJECTIVE: A study from South Africa reviewed 1 018 suicide cases in Pretoria over 4 years (1997 - 2000). Our study was undertaken to establish whether there have been substantial changes in the profile of suicide victims who died in Pretoria a decade later. METHODS: Case records at the Pretoria Medico-Legal Laboratory were reviewed retrospectively from 2007 to 2010...
July 28, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/28808628/distal-radius-volar-rim-plate-technical-and-radiographic-considerations
#15
Michelle Spiteri, Darren Roberts, Wayne Ng, Jamie Matthews, Dominic Power
AIM: To determine technical considerations and radiographic outcomes of the Synthes volar rim distal radius plate to treat complex intra-articular fractures. METHODS: This review highlights technical considerations learnt using this implant since it was introduced in a major trauma unit in November 2011, including anatomical reduction and whether this was maintained radiographically. RESULTS: Twenty-six of the 382 internally fixed distal radial fractures at our unit (6...
July 18, 2017: World Journal of Orthopedics
https://www.readbyqxmd.com/read/28808565/acute-pancreatitis-a-7-year-retrospective-cohort-study-of-the-epidemiology-aetiology-and-outcome-from-a-tertiary-hospital-in-jamaica
#16
Gail P Reid, Eric W Williams, Damian K Francis, Michael G Lee
BACKGROUND: Acute pancreatitis (AP) is a significant cause of acute abdominal pain, morbidity and hospitalisation. There was previously a dearth of studies exploring the incidence, risk factors and outcome of AP in the Caribbean region. MATERIALS AND METHODS: All patients with a diagnosis of AP admitted to the University Hospital of the West Indies (UHWI) between 2006 and 2012 were reviewed. The epidemiological profile, risk factors, clinical presentation and outcomes of patients with AP were retrospectively studied...
August 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28808492/assessment-of-anti-factor-xa-activity-of-enoxaparin-for-venous-thromboembolism-prophylaxis-in-morbidly-obese-surgical-patients
#17
Nouf Al Otaib, Zohour Bootah, Maha A Al Ammari, Tariq M Aldebasi, Abdulmalik M Alkatheri, Shmeylan A Al Harbi, Salah M AbuRuz, Abdulkareem M AlBekairy
BACKGROUND: Venous thromboembolism (VTE) can be encountered by 60% of hospitalized patients. Anticoagulants have been recommended to reduce the risk of VTE in patients with risk factors. However, no specific dosing recommendations for obese patients are provided in the current practice guidelines. The purpose of this study was to determine the efficacy and safety of weight-based dosing of enoxaparin for VTE prophylaxis among morbidly obese patients undergoing surgery. METHODS: Adult patients were enrolled if they have a body mass index (BMI) of ≥35 kg/m(2) and were scheduled for surgery...
July 2017: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/28808141/a-critical-role-for-plasma-kallikrein-in-the-pathogenesis-of-autoantibody-induced-arthritis
#18
Aizhen Yang, Junsong Zhou, Bo Wang, Jihong Dai, Robert W Colman, Wenchao Song, Yi Wu
The plasma kallikrein-kinin system (KKS) consists of serine proteases, prekallikrein (pKal) and factor XII (FXII), and a cofactor, high-MW kininogen (HK). Upon activation, activated pKal and FXII cleave HK to release bradykinin. Activation of this system has been noted in patients with rheumatoid arthritis, and its pathogenic role has been characterized in animal arthritic models. In this study, we generated 2 knockout mouse strains that lacked pKal and HK and determined the role of KKS in autoantibody-induced arthritis...
August 14, 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/28807850/anti-hiv-activity-of-southern-african-plants-current-developments-phytochemistry-and-future-research
#19
REVIEW
Gerhard Prinsloo, Cynthia K Marokane, Renée A Street
ETHNOPHARMACOLOGICAL RELEVANCE: The African continent is home to a large number of higher plant species used over centuries for many applications, which include treating and managing diseases such as HIV. Due to the overwhelming prevalence and incidence rates of HIV, especially in sub-Saharan Africa, it is necessary to develop new and affordable treatments. AIM OF THE STUDY: The article provides an extensive overview of the status on investigation of plants from the southern African region with ethnobotanical use for treating HIV or HIV-related symptoms, or the management of HIV...
August 11, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28807754/transgenerational-effects-of-early-environmental-insults-on-aging-and-disease-incidence
#20
REVIEW
Mirela Ambeskovic, Tessa J Roseboom, Gerlinde A S Metz
Adverse early life experiences are major influences on developmental trajectories with potentially life-long consequences. Prenatal or early postnatal exposure to stress, undernutrition or environmental toxicants may reprogram brain development and increase risk of behavioural and neurological disorders later in life. Not only experience within a single lifetime, but also ancestral experience affects health trajectories and chances of successful aging. The central mechanism in transgenerational programming of a disease may the formation of epigenetic memory...
August 11, 2017: Neuroscience and Biobehavioral Reviews
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