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https://www.readbyqxmd.com/read/27853297/changes-in-choroidal-thickness-follow-the-rnfl-changes-in-leber-s-hereditary-optic-neuropathy
#1
Enrico Borrelli, Giacinto Triolo, Maria Lucia Cascavilla, Chiara La Morgia, Giovanni Rizzo, Giacomo Savini, Nicole Balducci, Paolo Nucci, Rosa Giglio, Fatemeh Darvizeh, Vincenzo Parisi, Francesco Bandello, Alfredo A Sadun, Valerio Carelli, Piero Barboni
Leber's hereditary optic neuropathy (LHON) is typically characterized by vascular alterations in the acute phase. The aim of this study was to evaluate choroidal changes occurring in asymptomatic, acute and chronic stages of LHON. We enrolled 49 patients with LHON, 19 with Dominant Optic Atrophy (DOA) and 22 healthy controls. Spectral Domain-Optical Coherence Tomography (SD-OCT) scans of macular and peripapillary regions were performed in all subjects, to evaluate macular and peripapillary choroidal thickness, and retinal nerve fiber layer (RNFL) thicknes...
November 17, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27722757/comparison-of-al-scan-and-iolmaster-500-partial-coherence-interferometry-optical-biometers
#2
Kenneth J Hoffer, Giacomo Savini
PURPOSE: To investigate agreement between the ocular biometry measurements provided by a newer optical biometer, the AL-Scan (Nidek Co, Ltd., Gamagori, Japan) and those provided by the IOLMaster 500 (Carl Zeiss Meditec, Jena Germany), which are both based on partial coherence interferometry. METHODS: Axial length, corneal power, and anterior chamber depth (corneal epithelium to lens) were measured in 86 eyes of 86 patients scheduled for cataract surgery using both biometers...
October 1, 2016: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/27548454/hemorrhagic-occlusive-retinal-vasculitis-after-first-eye-cataract-surgery-without-subsequent-second-eye-involvement
#3
Nicole Balducci, Giacomo Savini, Piero Barboni, Pietro Ducoli, Antonio Ciardella
A case of monocular postoperative hemorrhagic occlusive retinal vasculitis (HORV) after uncomplicated bilateral cataract surgery is described. HORV is a severe syndrome that leads to painless visual loss after uncomplicated cataract surgery. The same surgical procedure was adopted in both eyes except for the use of intracameral vancomycin, which was injected only in the eye that developed HORV. Diffuse retinal ischemia with vascular sheathing and intraretinal hemorrhages were detected during the fourth postoperative day...
August 1, 2016: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/27531293/comparison-of-a-new-optical-biometer-using-swept-source-optical-coherence-tomography-and-a-biometer-using-optical-low-coherence-reflectometry
#4
Kenneth J Hoffer, Peter C Hoffmann, Giacomo Savini
PURPOSE: To investigate agreement between the IOLMaster 700 based on swept-source optical coherence tomography (SS-OCT) and the Lenstar LS 900 based on optical low-coherence reflectometry (OLCR). SETTING: Private practice, Castrop-Rouxelle, Germany. DESIGN: Prospective evaluation of diagnostic test. METHODS: Axial length (AL), keratometry (K), anterior chamber depth (corneal epithelium to lens) (ACD), lens thickness, and central corneal thickness (CCT) were measured in 183 eyes of 183 patients...
August 2016: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/27503393/repeatability-and-interobserver-reproducibility-of-a-new-optical-biometer-based-on-swept-source-optical-coherence-tomography-and-comparison-with-iolmaster
#5
Jinhai Huang, Giacomo Savini, Kenneth J Hoffer, Hao Chen, Weicong Lu, Qingjie Hu, Fangjun Bao, Qinmei Wang
OBJECTIVE: To evaluate the precision of the measurements in healthy subjects obtained with a new optical biometer (OA-2000, Tomey, Nagoya, Japan) using swept-source optical coherence tomography (SS-OCT) and compare these measurements with those provided by the IOLMaster v5.4 (Carl Zeiss Meditec AG, Jena, Germany) using partial coherence interferometry (PCI). METHODS: Axial length (AL), keratometry (K) over 2.5 mm and 3.0 mm diameters, anterior chamber depth (ACD) (corneal epithelium to lens), lens thickness (LT), central corneal thickness and corneal diameter (CD) were measured with SS-OCT by two experienced operators...
August 8, 2016: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/27403339/comparison-between-a-new-optical-biometry-device-and-an-anterior-segment-optical-coherence-tomographer-for-measuring-central-corneal-thickness-and-anterior-chamber-depth
#6
Jinhai Huang, Weicong Lu, Giacomo Savini, Hao Chen, Chengfang Wang, Xinxin Yu, Fangjun Bao, Qinmei Wang
Purpose. To compare between a new optical biometer (AL-Scan, Nidek Co., Aichi, Japan) and an anterior segment optical coherence tomographer (Visante AS-OCT, Carl Zeiss Meditec, Dublin, USA) for measuring central corneal thickness (CCT), anterior chamber depth (ACD), and aqueous depth (AD). Methods. Sixty-three eyes of 63 normal subjects were examined with AL-Scan and Visante AS-OCT in this prospective study. One eye per subject was measured three times with both devices to record their CCT, ACD, and AD. All procedures were performed by the same operator...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27387567/influence-of-posterior-corneal-astigmatism-on-total-corneal-astigmatism-in-eyes-with-keratoconus
#7
Giacomo Savini, Kristian Næser, Domenico Schiano-Lomoriello, Alessandro Mularoni
PURPOSE: To measure posterior corneal astigmatism (PCA) and investigate its influence on total corneal astigmatism (TCA) in eyes with keratoconus. METHODS: Keratometric astigmatism (KA), PCA, and TCA were investigated by means of a dual Scheimpflug analyzer in patients with keratoconus. Vector analysis was carried out with the Næser polar value method. RESULTS: We enrolled 119 eyes. PCA magnitude averaged 0.77 ± 0.43 diopters (D) and exceeded 0...
July 6, 2016: Cornea
https://www.readbyqxmd.com/read/27163619/estimating-the-preoperative-corneal-power-with-scheimpflug-imaging-in-eyes-that-have-undergone-myopic-lasik
#8
Giacomo Savini, Kenneth J Hoffer, Domenico Schiano-Lomoriello, Pietro Ducoli
PURPOSE: To investigate whether the Estimated Pre-Refractive SimK accurately predicts the preoperative corneal power (K) in eyes with previous myopic femtosecond laser-assisted LASIK (FS-LASIK) and whether a better prediction can be developed. METHODS: Preoperatively and 3 months after FS-LASIK, patients underwent anterior segment imaging with the Pentacam HR rotating Scheimpflug camera (Oculus Optikgeräte, Wetzlar, Germany). Posterior and anterior corneal curvature and power and asphericity (Q-value at 8 mm) were recorded...
May 1, 2016: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/27101093/object-engagement-and-manipulation-in-extremely-preterm-and-full-term-infants-at-6-months-of-age
#9
Mariagrazia Zuccarini, Alessandra Sansavini, Jana M Iverson, Silvia Savini, Annalisa Guarini, Rosina Alessandroni, Giacomo Faldella, Tiziana Aureli
Delays in the motor domain have been frequently observed in preterm children, especially those born at an extremely low gestational age (ELGA;<28 weeks GA). However, early motor exploration has received relatively little attention despite its relevance for object knowledge and its impact on cognitive and language development. The present study aimed at comparing early object exploration in 20 ELGA and 20 full-term (FT) infants at 6 months of age during a 5-minute mother-infant play interaction. Object engagement (visual vs manual), visual object engagement (no act vs reach), manual object engagement (passive vs active), and active object manipulation (mouthing, transferring, banging, turn/rotating, shaking, fingering) were analyzed...
August 2016: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/27061384/linguistic-features-in-children-born-very-preterm-at-preschool-age
#10
Annalisa Guarini, Andrea Marini, Silvia Savini, Rosina Alessandroni, Giacomo Faldella, Alessandra Sansavini
AIM: This cross-sectional study focused on the effect of very preterm (VPT) birth on language development by analysing phonological, lexical, grammatical, and pragmatic skills and assessing the role of cognitive and memory skills. METHOD: Sixty children (29 males, 31 females) born VPT (<32wks) aged 5 years were compared with 60 children with typical development. The linguistic assessment was performed by administering a battery of Italian tests for the evaluation of language; cognitive and memory skills were assessed by Raven's coloured progressive matrices and digit span subtest (Wechsler Intelligence Scale for Children [WISC-III])...
September 2016: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/27027623/agreement-between-predicted-and-measured-ablation-depth-after-femtosecond-laser-assisted-lasik-for-myopia
#11
Giacomo Savini, Arthur B Cummings, Nicole Balducci, Piero Barboni, Jinhai Huang, Marco Lombardo, Sebastiano Serrao, Pietro Ducoli
PURPOSE: To investigate agreement between the predicted ablation depth calculated by the EX500 excimer laser (Wavelight Laser Technologie AG, Erlangen, Germany) and the measured ablation depth in eyes that have undergone femtosecond laser-assisted LASIK (FS-LASIK) for myopia. METHODS: Corneal thickness was measured with a rotating Scheimpflug camera preoperatively and 3 months postoperatively and the difference between these values was defined as the measured ablation depth...
March 2016: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/26948780/measurement-agreement-between-a-new-biometer-based-on-partial-coherence-interferometry-and-a-validated-biometer-based-on-optical-low-coherence-reflectometry
#12
Junhua Li, Hao Chen, Giacomo Savini, Weicong Lu, Xinxin Yu, Fangjun Bao, Qinmei Wang, Jinhai Huang
PURPOSE: To evaluate the agreement of ocular measurements obtained with a new optical biometer (AL-Scan) and a previously validated optical biometer (Lenstar). SETTING: Eye Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China. DESIGN: Prospective observational cross-sectional study. METHODS: For a comprehensive comparison between the partial coherence interferometry (PCI) device and the optical low-coherence reflectometry (OLCR) device, the axial length (AL), central corneal thickness (CCT), anterior chamber depth (ACD), aqueous depth, mean keratometry (K), astigmatism, white-to-white (WTW), and pupil diameter were measured 3 times per device in eyes with cataract...
January 2016: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/26948779/multicenter-study-of-optical-low-coherence-interferometry-and-partial-coherence-interferometry-optical-biometers-with-patients-from-the-united-states-and-china
#13
Kenneth J Hoffer, H John Shammas, Giacomo Savini, Jinhai Huang
PURPOSE: To evaluate the agreement between the measurements provided by a new optical biometer, the Aladdin, based on optical low-coherence interferometry (OLCI), and those provided by the most commonly used optical biometer (IOLMaster 500), based on partial-coherence interferometry (PCI). SETTING: Multicenter clinical trial. DESIGN: Prospective evaluation of diagnostic test. METHODS: In this study, 2 samples of adult patients were enrolled, 1 in the United States and the other in China...
January 2016: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/26948777/influence-of-the-effective-lens-position-as-predicted-by-axial-length-and-keratometry-on-the-near-add-power-of-multifocal-intraocular-lenses
#14
Giacomo Savini, Kenneth J Hoffer, Marco Lombardo, Sebastiano Serrao, Domenico Schiano-Lomoriello, Pietro Ducoli
PURPOSE: To calculate the near focal distance of different multifocal intraocular lenses (IOLs) as a function of the 2 parameters that are measured before cataract surgery; that is, axial length (AL) and refractive corneal power (keratometry [K]). SETTING: GB Bietti Foundation IRCCS, Rome, Italy. DESIGN: Noninterventional theoretical study. METHODS: The IOL power for emmetropia was first calculated in an eye model with the AL ranging from 20 to 30 mm and K from 38 to 48 diopters (D)...
January 2016: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/26812710/objective-monitoring-of-corneal-backward-light-scattering-after-femtosecond-laser-assisted-lasik
#15
Giacomo Savini, Jinhai Huang, Marco Lombardo, Sebastiano Serrao, Domenico Schiano-Lomoriello, Simona Venanzio, Pietro Ducoli
PURPOSE: To investigate the changes in corneal backward light scattering, as measured by a rotating Scheimpflug camera with automated corneal densitometry software, in eyes treated with femtosecond laser-assisted LASIK (FS-LASIK). METHODS: The cornea was examined preoperatively and postoperatively at 1 day, 1 week, and 1, 3, and 6 months in 23 patients who underwent myopic FS-LASIK. Local analysis of corneal backscatter was performed on four concentric radial zones across a 12-mm diameter (0 to 2, 2 to 6, 6 to 10, and 10 to 12 mm) and at a different corneal depth (anterior 120 µm, central and posterior 60 µm)...
January 2016: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/26701690/corneal-powers-measured-with-a-rotating-scheimpflug-camera
#16
Kristian Næser, Giacomo Savini, Jesper Flethøj Bregnhøj
BACKGROUND/AIM: Keratometry measures the anterior corneal curvature only. Corneal power is calculated by multiplication with the keratometric refractive index, which takes into account the average negative posterior corneal power. The aim of this study was to calculate and compare various expressions for total corneal power assessed with Scheimpflug camera techniques, which also measure the posterior corneal curvature. METHODS: We used the Pentacam rotating Scheimpflug camera to measure the equivalent power, total corneal refractive power (based on Snell's law ray tracing), and simulated keratometry (keratometric refractive index=1...
September 2016: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/26614631/macular-nerve-fibre-and-ganglion-cell-layer-changes-in-acute-leber-s-hereditary-optic-neuropathy
#17
Nicole Balducci, Giacomo Savini, Maria Lucia Cascavilla, Chiara La Morgia, Giacinto Triolo, Rosa Giglio, Michele Carbonelli, Vincenzo Parisi, Alfredo A Sadun, Francesco Bandello, Valerio Carelli, Piero Barboni
AIMS: To evaluate longitudinal retinal ganglion cell inner plexiform layer (GC-IPL) and macular retinal nerve fibre layer (mRNFL) thickness changes in acute Leber's hereditary optic neuropathy (LHON). METHODS: Six eyes of four patients with LHON underwent SD-OCT (optical coherence tomography) at month 1, 3, 6 and 12 after visual loss. In two eyes, the examination was carried out in the presymptomatic stage. The relationship and curves for area under the receiver operator characteristic (AUROC) were generated to assess the ability of each parameter to detect ganglion cell loss...
September 2016: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/26603399/anterior-chamber-depth-studies
#18
COMPARATIVE STUDY
Kenneth J Hoffer, Giacomo Savini
PURPOSE: To compare the anterior chamber depth (ACD; corneal epithelium to lens) using 3 modalities and compare the change 1 day and 3 months postoperatively. SETTING: Private practice, Santa Monica, California, USA. DESIGN: Nonrandomized prospective series. METHODS: The mean optical pachymetry and immersion ultrasound (US) of the ACD and partial coherence interferometry (PCI) were measured. Optical pachymetry ACD was measured in 675 eyes postoperatively at 1 day and 3 months...
September 2015: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/26603397/intraocular-lens-power-calculation-after-myopic-excimer-laser-surgery-selecting-the-best-method-using-available-clinical-data
#19
COMPARATIVE STUDY
Giacomo Savini, Piero Barboni, Michele Carbonelli, Pietro Ducoli, Kenneth J Hoffer
PURPOSE: To compare the results of methods to calculate intraocular lens (IOL) power after myopic excimer laser surgery. SETTING: G.B. Bietti Foundation-IRCCS, Rome, Italy. DESIGN: Prospective interventional case series. METHODS: Eyes were classified into 4 groups: Group 1 (preoperative keratometry available, refractive change known), Group 2 (preoperative keratometry available, refractive change uncertain), Group 3 (preoperative keratometry unavailable, refractive change known), and Group 4 (preoperative keratometry unavailable, refractive change unknown)...
September 2015: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/26600254/the-repeatability-assessment-of-three-dimensional-capsule-intraocular-lens-complex-measurements-by-means-of-high-speed-swept-source-optical-coherence-tomography
#20
Xixia Ding, Qinmei Wang, Pingjun Chang, Jin Li, Giacomo Savini, Jinhai Huang, Shenghai Huang, Yinying Zhao, Na Liao, Lei Lin, Xiaoyu Yu, Yun-e Zhao
PURPOSE: To rebuild the three-dimensional (3-D) model of the anterior segment by high-speed swept-source optical coherence tomography (SSOCT) and evaluate the repeatability of measurement for the parameters of capsule-intraocular lens (C-IOL) complex. METHODS: Twenty-two pseudophakic eyes from 22 patients were enrolled. Three continuous SSOCT measurements were performed in all eyes and the tomograms obtained were used for 3-D reconstruction. The output data were used to evaluate the measurement repeatability...
2015: PloS One
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