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https://www.readbyqxmd.com/read/28075318/deserving-desire-women-s-stories-of-sexual-evolution
#1
Anita P Hoffer
No abstract text is available yet for this article.
January 2, 2017: Journal of Sex & Marital Therapy
https://www.readbyqxmd.com/read/28050320/changes-in-anterior-chamber-depth-after-phacoemulsification-in-pseudoexfoliative-eyes-and-their-effect-on-accuracy-of-intraocular-lens-power-calculation
#2
Sirel Gür Güngör, Ahmet Akman, Leyla Asena, Mustafa Aksoy, Almila Sarıgül Sezenöz
OBJECTIVES: To compare anterior chamber depth (ACD) changes after phacoemulsification surgery in patients with pseudoexfoliation syndrome (PEX) and normal patients using an anterior segment imaging method. Another aim of this study was to evaluate the effect of these changes on the accuracy of intraocular lens (IOL) power calculation and postoperative refraction. MATERIALS AND METHODS: Twenty-two eyes of 22 patients with PEX and 30 eyes of 30 normal patients who underwent uneventful phacoemulsification surgery and IOL implantation were included in the study...
December 2016: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28031003/regarding-is-the-guideline-already-out-of-date
#3
L John Hoffer, Bruce R Bistrian
No abstract text is available yet for this article.
January 2017: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28031002/response-to-letter-from-hoffer-and-bistrian
#4
Ronald L Koretz
No abstract text is available yet for this article.
January 2017: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/27956289/pterygium-size-and-effect-on-intraocular-lens-power-calculation
#5
Mustafa Koc, Mehmet Murat Uzel, Emre Aydemir, Fuat Yavrum, Pinar Kosekahya, Pelin Yılmazbaş
PURPOSE: To evaluate the effects of pterygium on biometry measurements and the relationship between these effects and pterygium size. SETTING: Ulucanlar Eye Hospital, Ankara, Turkey. DESIGN: Prospective comparative study. METHODS: Patients who had unilateral primary pterygium excision were included in the study group. Anterior segment photographed images were taken of eyes with pterygia to calculate the pterygium length and area using the ImageJ program...
November 2016: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/27932264/physician-attitudes-toward-participating-in-a-financial-incentive-program-for-ldl-reduction-are-associated-with-patient-outcomes
#6
Tianyu Liu, David A Asch, Kevin G Volpp, Jingsan Zhu, Wenli Wang, Andrea B Troxel, Aderinola Adejare, Darra D Finnerty, Karen Hoffer, Judy A Shea
No abstract text is available yet for this article.
December 5, 2016: Healthcare
https://www.readbyqxmd.com/read/27898058/ccl5-rantes-contributes-to-hypothalamic-insulin-signaling-for-systemic-insulin-responsiveness-through-ccr5
#7
Szu-Yi Chou, Reni Ajoy, Chun Austin Changou, Ya-Ting Hsieh, Yang-Kao Wang, Barry Hoffer
Many neurodegenerative diseases are accompanied by metabolic disorders. CCL5/RANTES, and its receptor CCR5 are known to contribute to neuronal function as well as to metabolic disorders such as type 2 diabetes mellitus, obesity, atherosclerosis and metabolic changes after HIV infection. Herein, we found that the lack of CCR5 or CCL5 in mice impaired regulation of energy metabolism in hypothalamus. Immunostaining and co-immunoprecipitation revealed the specific expression of CCR5, associated with insulin receptors, in the hypothalamic arcuate nucleus (ARC)...
November 29, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27872409/complexity-analysis-of-decision-making-in-the-critically-ill
#8
Barbara J Daly, Sara L Douglas, Elizabeth O'Toole, James Rowbottom, Alan Hoffer, Amy R Lipson, Christopher Burant
RATIONALE: Despite multiple trials of interventions to improve end-of-life care of the critically ill, there is a persistent lack of understanding of factors associated with barriers to decision-making at the end of life. OBJECTIVE: To apply the principles of complexity science in examining the extent to which transitions to end-of-life care can be predicted by physician, family, or patient characteristics; outcome expectations; and the evaluation of treatment effectiveness...
November 20, 2016: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/27862363/a-comprehensive-microbiological-safety-approach-for-agarose-encapsulated-porcine-islets-intended-for-clinical-trials
#9
Lawrence S Gazda, James Collins, Archie Lovatt, Robert W Holdcraft, Merribeth J Morin, Daniel Galbraith, Melanie Graham, Melissa A Laramore, Christine Maclean, John Black, Euan W Milne, Douglas G Marthaler, Horatiu V Vinerean, Michelle M Michalak, Deborah Hoffer, Steven Richter, Richard D Hall, Barry H Smith
BACKGROUND: The use of porcine islets to replace insulin-producing islet β-cells, destroyed during the diabetogenic disease process, presents distinct challenges if this option is to become a therapeutic reality for the treatment of type 1 diabetes. These challenges include a thorough evaluation of the microbiological safety of the islets. In this study, we describe a robust porcine islet-screening program that provides a high level of confidence in the microbiological safety of porcine islets suitable for clinical trials...
November 2016: Xenotransplantation
https://www.readbyqxmd.com/read/27849008/ku70-serine-155-mediates-aurora-b-inhibition-and-activation-of-the-dna-damage-response
#10
Victoria L Fell, Elizabeth A Walden, Sarah M Hoffer, Stephanie R Rogers, Amelia S Aitken, Louisa M Salemi, Caroline Schild-Poulter
The Ku heterodimer (Ku70/Ku80) is the central DNA binding component of the classical non-homologous end joining (NHEJ) pathway that repairs DNA double-stranded breaks (DSBs), serving as the scaffold for the formation of the NHEJ complex. Here we show that Ku70 is phosphorylated on Serine 155 in response to DNA damage. Expression of Ku70 bearing a S155 phosphomimetic substitution (Ku70 S155D) in Ku70-deficient mouse embryonic fibroblasts (MEFs) triggered cell cycle arrest at multiple checkpoints and altered expression of several cell cycle regulators in absence of DNA damage...
November 16, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27803805/nutrition-in-critical-illness-a-current-conundrum
#11
REVIEW
L John Hoffer, Bruce R Bistrian
Critically ill people are unable to eat. What's the best way to feed them? Nutrition authorities have long recommended providing generous amounts of protein and calories to critically ill patients, either intravenously or through feeding tubes, in order to counteract the catabolic state associated with this condition. In practice, however, patients in modern intensive care units are substantially underfed. Several large randomized clinical trials were recently carried out to determine the clinical implications of this situation...
2016: F1000Research
https://www.readbyqxmd.com/read/27758940/ices-intraoperative-stereotactic-computed-tomography-guided-endoscopic-surgery-for-brain-hemorrhage-a-multicenter-randomized-controlled-trial
#12
Paul Vespa, Daniel Hanley, Joshua Betz, Alan Hoffer, Johnathan Engh, Robert Carter, Peter Nakaji, Chris Ogilvy, Jack Jallo, Warren Selman, Amanda Bistran-Hall, Karen Lane, Nichol McBee, Jeffery Saver, Richard E Thompson, Neil Martin
BACKGROUND AND PURPOSE: Intracerebral hemorrhage (ICH) is a devastating disease without a proven therapy to improve long-term outcome. Considerable controversy about the role of surgery remains. Minimally invasive endoscopic surgery for ICH offers the potential of improved neurological outcome. METHODS: We tested the hypothesis that intraoperative computerized tomographic image-guided endoscopic surgery is safe and effectively removes the majority of the hematoma rapidly...
November 2016: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/27722757/comparison-of-al-scan-and-iolmaster-500-partial-coherence-interferometry-optical-biometers
#13
Kenneth J Hoffer, Giacomo Savini
PURPOSE: To investigate agreement between the ocular biometry measurements provided by a newer optical biometer, the AL-Scan (Nidek Co, Ltd., Gamagori, Japan) and those provided by the IOLMaster 500 (Carl Zeiss Meditec, Jena Germany), which are both based on partial coherence interferometry. METHODS: Axial length, corneal power, and anterior chamber depth (corneal epithelium to lens) were measured in 86 eyes of 86 patients scheduled for cataract surgery using both biometers...
October 1, 2016: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/27716304/appropriate-vitamin-d-loading-regimen-for-patients-with-advanced-lung-cancer
#14
L John Hoffer, Line Robitaille, Nelda Swinton, Jason Agulnik, Victor Cohen, David Small, Carmela Pepe, Shaun Eintracht
BACKGROUND: Most patients attending cancer clinics have hypovitaminosis D. Correcting or preventing this abnormal condition could mitigate the emotional and physical complications of their disease, but clinical trials of vitamin D therapy in this setting are hindered by the unavailability of safe, effective and practical loading dose regimens. METHODS: In this single arm open-label pharmacokinetic trial, outpatients with advanced lung cancer consumed 20,000 IU vitamin D daily with the largest meal of the day for 14 days followed by 10,000 IU per day for a further 7 days...
October 6, 2016: Nutrition Journal
https://www.readbyqxmd.com/read/27681416/uniformity-of-peptide-release-is-maintained-by-methylation-of-release-factors
#15
William E Pierson, Eric D Hoffer, Hannah E Keedy, Carrie L Simms, Christine M Dunham, Hani S Zaher
Termination of protein synthesis on the ribosome is catalyzed by release factors (RFs), which share a conserved glycine-glycine-glutamine (GGQ) motif. The glutamine residue is methylated in vivo, but a mechanistic understanding of its contribution to hydrolysis is lacking. Here, we show that the modification, apart from increasing the overall rate of termination on all dipeptides, substantially increases the rate of peptide release on a subset of amino acids. In the presence of unmethylated RFs, we measure rates of hydrolysis that are exceptionally slow on proline and glycine residues and approximately two orders of magnitude faster in the presence of the methylated factors...
September 27, 2016: Cell Reports
https://www.readbyqxmd.com/read/27661991/refractive-outcome-of-cataract-surgery-in-eyes-with-prior-trabeculectomy-risk-factors-for-postoperative-myopia
#16
Oliver L Yeh, Karine D Bojikian, Mark A Slabaugh, Philip P Chen
PURPOSE: To examine refractive outcomes after phacoemulsification in eyes with prior trabeculectomy. DESIGN: Retrospective observational case-control study METHODS:: Comparison of eyes of glaucoma patients undergoing cataract surgery after trabeculectomy (study group) with a matched group with medically controlled glaucoma (control group). Laser interferometry was used to obtain ocular biometry. We measured the difference between the expected and actual postoperative refraction using third-generation and fourth-generation intraocular lens (IOL) prediction formulae (Haigis, Holladay 2, Hoffer Q, and SRK-T)...
January 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/27660532/first-report-of-cheiloneurus-exitiosus-perkins-1906-and-helegonatopus-dimorphus-hoffer-1954-hymenoptera-encyrtidae-from-japan-with-remarks-on-their-abundance-in-rice-paddies
#17
Toshiharu Mita, Hironobu Handa, Yoshimitsu Higashiura, George Japoshvili
BACKGROUND: Encyrtid secondary parasitoids of Delphacidae have not been recorded in Japan. However, they may play an important role in the rice ecosystem because they can reduce the number of Dryinidae, the natural enemies of rice planthoppers. NEW INFORMATION: We found two encyrtid species, Cheiloneurus exitiosus (Perkins, 1906) and Helegonatopus dimorphus (Hoffer, 1954), from rice paddies and the surrounding environment. Haplogonatopus oratorius (Westwood, 1833) and Anteon sp...
2016: Biodiversity Data Journal
https://www.readbyqxmd.com/read/27658366/rethinking-autonomy-relationships-as-a-source-of-resilience-in-a-changing-healthcare-system
#18
EDITORIAL
Jody Hoffer Gittell
No abstract text is available yet for this article.
October 2016: Health Services Research
https://www.readbyqxmd.com/read/27638079/posttraumatic-dizziness-and-vertigo
#19
M Szczupak, M E Hoffer, S Murphy, C D Balaban
Traumatic brain injury is an increasingly common public health issue, with the mild variant most clinically relevant for this chapter. Common causes of mild traumatic brain injury (mTBI) include motor vehicle accidents, athletics, and military training/deployment. Despite a range of clinically available testing platforms, diagnosis of mTBI remains challenging. Symptoms are primarily neurosensory, and include dizziness, hearing problems, headaches, cognitive, and sleep disturbances. Dizziness is nearly universally present in all mTBI patients, and is the easiest symptom to objectify for diagnosis...
2016: Handbook of Clinical Neurology
https://www.readbyqxmd.com/read/27619562/inhibition-of-drp1-mitochondrial-translocation-provides-neural-protection-in-dopaminergic-system-in-a-parkinson-s-disease-model-induced-by-mptp
#20
Emily Filichia, Barry Hoffer, Xin Qi, Yu Luo
Accumulating evidence suggest mitochondria-mediated pathways play an important role in dopaminergic neuronal cell death in Parkinson's disease (PD). Drp1, a key regulator of mitochondrial fission, has been shown to be activated and translocated to mitochondria under stress, leading to excessive mitochondria fission and dopaminergic neuronal death in vitro. However, whether Drp1 inhibition can lead to long term stable preservation of dopaminergic neurons in PD-related mouse models remains unknown. In this study, using a classical MPTP animal PD model, we showed for the first time Drp1 activation and mitochondrial translocation in vivo after MPTP administration...
September 13, 2016: Scientific Reports
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