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Cholesteatoma

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https://www.readbyqxmd.com/read/28195998/a-meta-analysis-on-the-diagnostic-performance-of-non-echoplanar-diffusion-weighted-imaging-in-detecting-middle-ear-cholesteatoma-10-years-on
#1
Ravi K Lingam, Paul Bassett
OBJECTIVE: To describe via a meta-analysis of the published literature, the performance of non-echo-planar diffusion weighted imaging (DWI) in detecting middle ear cholesteatoma. METHODOLOGY: A systematic review of the published literature was performed to identify original studies evaluating the diagnostic performance of non-echo-planar DWI in detecting middle ear cholesteatoma. Only studies with surgical correlation were included. A bi-variate meta-analysis and hierarchical summary receiver operating characteristic model was performed...
February 10, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28187055/masticator-space-abscess-arising-from-a-spontaneous-external-auditory-canal-cholesteatoma
#2
Ryan Smith, Shawn M Stevens, Ravi N Samy
No abstract text is available yet for this article.
February 9, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28184249/atlantoaxial-rotatory-fixation-as-a-rare-complication-from-head-positioning-in-otologic-surgery-report-of-two-cases-in-young-children
#3
Hiroshi Sakaida, Koji Akeda, Akihiro Sudo, Kazuhiko Takeuchi
BACKGROUND: Atlantoaxial rotatory fixation is a condition in which the first and second vertebrae of the cervical spine become interlocked in a rotated position. This condition can result in serious consequences and thus have a significant impact on patients, especially when diagnosis and treatment are delayed. Some cases of atlantoaxial rotatory fixation have been described in association with otologic surgery or plastic surgery involving the ear. We present the cases of two pediatric patients who developed atlantoaxial rotatory fixation following otologic surgery and we review the relevant literature...
2017: Patient Safety in Surgery
https://www.readbyqxmd.com/read/28167016/lateral-skull-base-surgery-in-a-pediatric-population-a-25-year-experience-in-a-referral-skull-base-center
#4
Golda Grinblat, Sampath Chandra Prasad, Andrea Fulcheri, Melissa Laus, Alessandra Russo, Mario Sanna
OBJECTIVE: To analyze the pathology and surgical outcomes of lateral skull base (LSB) procedures in a pediatric population. STUDY DESIGN: Retrospective case review in a referral skull base center. METHODS: Charts of pediatric patients who underwent defined LSB procedures from 1983 to 2015 for various pathologies were evaluated at our center. A systematic review of literature was performed and our results were compared with the literature. RESULTS: 63 patients presented with 65 diseased ears...
March 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28161243/facial-nerve-paralysis-associated-with-temporal-bone-masses
#5
Hironobu Nishijima, Kenji Kondo, Ryoji Kagoya, Hitoshi Iwamura, Kazuo Yasuhara, Tatsuya Yamasoba
OBJECTIVE: To investigate the clinical and electrophysiological features of facial nerve paralysis (FNP) due to benign temporal bone masses (TBMs) and elucidate its differences as compared with Bell's palsy. METHODS: FNP assessed by the House-Brackmann (HB) grading system and by electroneurography (ENoG) were compared retrospectively. RESULTS: We reviewed 914 patient records and identified 31 patients with FNP due to benign TBMs. Moderate FNP (HB Grades II-IV) was dominant for facial nerve schwannoma (FNS) (n=15), whereas severe FNP (Grades V and VI) was dominant for cholesteatomas (n=8) and hemangiomas (n=3)...
February 1, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28158903/tympanomastoid-cholesterol-granulomas-immunohistochemical-evaluation-of-angiogenesis
#6
Giannicola Iannella, Cira Di Gioia, Raffaella Carletti, Giuseppe Magliulo
OBJECTIVES/HYPOTHESIS: This study investigates the immunohistochemical expression of vascular endothelial growth factor (VEGF) and CD34 in patients treated for middle ear and mastoid cholesterol granulomas to evaluate the angiogenesis and vascularization of this type of lesion. A correlation between the immunohistochemical data and the radiological and intraoperative evidence of temporal bone marrow invasion and blood source connection was performed to validate this hypothesis. STUDY DESIGN: Retrospective study...
February 3, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28140829/the-petrosquamous-stalactite
#7
Michael D Puricelli, Maxwell D Newby, Andrew J Fishman, Arnaldo L Rivera
Objective To define the presence and relationship of the petrosquamous stalactite (PsS)-a condensation of the trabecular Korner's septum into a bony plate of the petrosquamous suture-to surrounding structures and understand its surgical implications. Study Design Series of cadaver dissections. Setting University of Missouri Alumni Temporal Bone and Microvascular Laboratory. Subjects and Methods Anatomic dissections were conducted on 15 consecutive formalin-preserved and frozen adult human temporal bones. A calibrated Dino-Lite Premier Digital Microscope was used to photograph dissections of each bone...
January 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28125327/mastoid-obliteration-with-s53p4-bioactive-glass-in-cholesteatoma-surgery
#8
Pieter D de Veij Mestdagh, David R Colnot, Pepijn A Borggreven, Claudia C Orelio, Jasper J Quak
CONCLUSION: Evaluation of the follow-up of 67 patients shows that S53P4 bioactive glass (BAG) granules are safe and effective as obliteration material in cholesteatoma surgery. OBJECTIVES: To investigate the safety and efficacy of mastoid obliteration using S53P4 BAG in cholesteatoma surgery. Clinical outcomes were infection control (Merchant's grading), cholesteatoma recidivism, and audiometric performance. METHODS: Retrospective follow-up study at the Diakonessenhuis, Utrecht, the Netherlands...
January 26, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28122112/mucous-retention-cyst-of-mastoid-bone-mimicking-cholesteatoma
#9
Nurdoğan Ata, Suna Erkılıç
No abstract text is available yet for this article.
January 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/28119094/regenerative-treatment-for-tympanic-membrane-perforation-using-gelatin-sponge-with-basic-fibroblast-growth-factor
#10
Kaoru Omae, Shin-Ichi Kanemaru, Eiji Nakatani, Hideaki Kaneda, Tsutomu Nishimura, Risa Tona, Yasushi Naito, Atsuhiko Kawamoto, Masanori Fukushima
OBJECTIVE: The objective of this study was to evaluate safety and efficacy of regenerative treatment using gelatin sponge with basic fibroblast growth factor (bFGF) in patients with tympanic membrane perforation (TMP). METHODS: The current study was a prospective, multicenter, open-label, single-arm, and exploratory clinical trial to evaluate the safety and efficacy of the TM regeneration procedure (TMRP). Myringotomy was used to mechanically disrupt the edge of the TMP, and a gelatin sponge immersed in bFGF was then placed over the perforation...
January 21, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28116997/the-burden-and-epidemiology-of-eustachian-tube-dysfunction-in-adults
#11
Peter M Vila, Tom Thomas, Carrie Liu, Dennis Poe, Jennifer J Shin
Objectives Pediatric eustachian tube dysfunction (ETD), otitis media with effusion (OME), and tympanic membrane retraction (TMR) have been well studied, but no large analyses have described the associated burden beyond childhood. The potential impact and feasibility of prospective trials designed to optimize management of affected adults are thus unclear. Our objectives were therefore (1) to determine the national visit burden associated with ETD/OME/TMR beyond childhood and (2) to examine risk factors specific to adults, highlighting differences in comparison with children...
February 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28106625/long-term-hearing-results-after-ossiculoplasty
#12
Matthew D Cox, Aaron Trinidade, James Shep Russell, John L Dornhoffer
OBJECTIVES: To determine if the OOPS index is predictive of long-term hearing results after ossiculoplasty. STUDY DESIGN: Case series with retrospective chart review. SETTING: Tertiary care otology practice. PATIENTS: Adult and pediatric patients (3-88 years of age). INTERVENTIONS: Ossiculoplasty with cartilage tympanoplasty, with or without mastoidectomy. OUTCOME MEASURES: Primary outcome measures included short-term hearing results (pure-tone average air-bone gap [PTA-ABG] measured between 60 days and 1 year after surgery), long-term hearing results (PTA-ABG measured ≥5 years after surgery), and the rate of successful ABG closure to ≤20 dB...
January 18, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28073243/cytokeratin-13-cytokeratin-17-and-ki-67-expression-in-human-acquired-cholesteatoma-and-their-correlation-with-its-destructive-capacity
#13
Mahmood A Hamed, Seiichi Nakata, Kazuya Shiogama, Kenji Suzuki, Ramadan H Sayed, Yoichi Nishimura, Noboru Iwata, Kouhei Sakurai, Badawy S Badawy, Ken-Ichi Inada, Hayato Tsuge, Yutaka Tsutsumi
Objectives: Cholesteatoma is a nonneoplastic destructive lesion of the temporal bone with debated pathogenesis and bone resorptive mechanism. Both molecular and cellular events chiefly master its activity. Continued research is necessary to clarify factors related to its aggressiveness. We aimed to investigate the expression of Ki-67, cytokeratin 13 (CK13) and cytokeratin 17 (CK17) in acquired nonrecurrent human cholesteatoma and correlate them with its bone destructive capacity. Methods: A prospective quantitative immunohistochemical study was carried out using fresh acquired cholesteatoma tissues (n=19), collected during cholesteatoma surgery...
January 12, 2017: Clinical and Experimental Otorhinolaryngology
https://www.readbyqxmd.com/read/28071070/surgery-for-cholesteatomatous-labyrinthine-fistula
#14
John Lim, Anupriya Gangal, Michael Brian Gluth
OBJECTIVE: There is uncertainty regarding the ideal surgical management of cholesteatomatous labyrinthine fistulae. The objective was to review the published evidence to determine whether a difference exists in hearing outcome for cholesteatoma matrix removal or matrix exteriorization. DATA SOURCES: Systematic MEDLINE and Web of Science searches identified publications describing hearing results after cholesteatoma matrix removal or matrix exteriorization. REVIEW METHODS: Three reviewers appraised the studies for quality, level of evidence, and extracted data...
January 1, 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28069077/successful-obliteration-of-troublesome-and-chronically-draining-cavities
#15
S Geerse, F A Ebbens, M J F de Wolf, E van Spronsen
OBJECTIVE: This study aimed to evaluate the results of revision radical cavity surgery with mastoid obliteration using a standardised grading scheme. METHODS: A retrospective study was performed of 121 patients (122 ears) with chronically draining ears who underwent revision radical cavity surgery with mastoid obliteration between 2007 and 2013. Surgical indications, patient characteristics, pre- and post-operative Merchant grade, and surgical outcomes were recorded...
February 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/28061926/baro-otolagia-secondary-to-cholesteatoma
#16
Revadi Govindaraju, Meenakshi Adaikappan, Raman Rajagopalan
BACKGROUND: Baro-otalgia is a common complaint among passengers in an aircraft, in particular those who had a recent upper respiratory tract infection. The underlying pathophysiology is secondary to unequal aeration of the middle ear cleft with the surrounding atmosphere and it can be explained using Boyle's Law. We describe an unusual presentation of baro-otalgia in a pilot secondary to cholesteatoma obstructing the aditus despite normal middle ear pressure equalization provided by a grommet in the ear...
January 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28059056/eaono-jos-joint-consensus-statements-on-the-definitions-classification-and-staging-of-middle-ear-cholesteatoma
#17
REVIEW
Matthew Yung, Tetsuya Tono, Ewa Olszewska, Yutaka Yamamoto, Holger Sudhoff, Masafumi Sakagami, Jef Mulder, Hiromi Kojima, Armağan İncesulu, Franco Trabalzini, Nuri Özgirgin
The European Academy of Otology and Neurotology (EAONO) has previously published a consensus document on the definitions and classification of cholesteatoma. It was based on the Delphi consensus methodology involving the broad EAONO membership. At the same time, the Japanese Otological Society (JOS) had been working independently on the "Classification and Staging of Cholesteatoma." EAONO and JOS then decided to collaborate and produce a joint consensus document. The EAONO/JOS joint consensus on "Definitions, Classification and Staging of Middle Ear Cholesteatoma" was formally presented at the 10th International Conference on Cholesteatoma and Ear Surgery in Edinburgh, June 5-8, 2016...
6, 2017: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/28050207/is-there-a-system%C3%A4-c-inflammatory-effect-of-cholesteatoma
#18
M Mustafa Kılıçkaya, Giray Aynali, Mustafa Tuz, Özkan Bagcı
Introduction Inflammation causes squamous epithelial transformation of the mucosa in the middle ear cavity and plays a role in the onset, growth, spread, and recurrence of cholesteatoma. Objectives The objective of this study is to investigate the systemic inflammatory effect in chronic otitis with cholesteatoma. Methods The study included a total of 311 patients comprising 156 patients with a pathology diagnosis of cholesteatoma and a control group of 155 with no active inflammation. The Neutrophil-to-lymphocyte Ratio (NLR) was calculated by dividing the neutrophil value by the lymphocyte value...
January 2017: International Archives of Otorhinolaryngology
https://www.readbyqxmd.com/read/28041650/attic-cholesteatoma-with-closure-of-the-entrance-to-pars-flaccida-retraction-pocket
#19
Shingo Matsuzawa, Yukiko Iino, Daiki Yamamoto, Masayo Hasegawa, Mariko Hara, Akihiro Shinnabe, Hiromi Kanazawa, Naohiro Yoshida
We report three patients with pars flaccida-type cholesteatoma (attic cholesteatoma) with closure of the entrance to the cholesteatoma at the time of surgery. These patients were diagnosed with attic cholesteatoma requiring surgery on the basis of abnormal findings of the pars flaccida, audiometry, and temporal bone computed tomography during the clinical course. Intraoperatively, cholesteatoma matrix and granulation tissue were observed behind the intact pars flaccida epithelium, which suggested that the entrance had apparently closed and the continuity with the cholesteatoma matrix disappeared after resolution of inflammation at the pars flaccida...
December 29, 2016: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/28031158/an-iatrogenic-cholesteatoma-of-the-squamous-part-of-the-temporal-bone
#20
Daniela Páez Mantilla, Claudio Krstulovic, Manuel Mateos Fernández, Herminio Pérez Garrigues
A cholesteatoma is a relatively common condition within the middle ear cavity, whereas a cholesteatoma of the squamous part of the temporal bone is an exceptionally rare entity. A case of an iatrogenic cholesteatoma located in the squamous part of the temporal bone is presented, which was revealed by an intermittent purulent discharge from an opening above the right ear 20 years after retroauricular myringoplasty. The diagnosis of an iatrogenic cholesteatoma is often made after several years of evolution, sometimes even at the stage of complications...
December 2016: Journal of International Advanced Otology
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