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https://www.readbyqxmd.com/read/27924713/acetylcholinesterase-and-neuropathy-target-esterase-activities-in-11-cases-of-symptomatic-flight-crew-members-after-fume-events
#1
Astrid R R Heutelbeck, Catherine Bornemann, Martina Lange, Anke Seeckts, Michael M Müller
In modern aviation, so-called fume events such as exposure to an unknown mixture of chemicals introduced into the aircraft cabin with bleed air drawn off at the engines may occur. Human exposure may result in (neuro)toxic symptoms described as so-called "aerotoxic syndrome." Currently, among other agents organophosphates (OP) are regarded as a likely cause of the observed adverse effects. After fume events 11 flight crew members (9 female/2 male; ages 23-58 yr) were admitted for a medical examination within 5 d post exposure...
2016: Journal of Toxicology and Environmental Health. Part A
https://www.readbyqxmd.com/read/27923335/-arrived-in-germany-when-children-who-have-fled-tell-their-stories
#2
Katharina Gerarts, Sabine Andresen, Ulrike Ravens-Sieberer, Fionna Klasen
Arrived in Germany: When Children Who have Fled Tell their Stories For this study, we listened to children who had fled with their families. We made a very conscious decision to focus on accompanied minors who have been displaced, because they go through the standard asylum system with their parent/guardian, which is why they often remain "invisible" as regards their own needs and their specific situation. We gave accompanied children who had fled a space where they could tell their stories and asked them to talk about their memories of their countries of origin, their experiences during their journey and on arrival in Germany, and their lives here, their concerns, but also their hopes and desires...
December 2016: Praxis der Kinderpsychologie und Kinderpsychiatrie
https://www.readbyqxmd.com/read/27898553/the-aeromedical-physician-assistant
#3
Joshua Radi, Michael Brisson, Michael Line
The US Army aeromedical physician assistant (PA) serves aviation units in regards to crewmember medical readiness. All PAs are graduates of a 6-week flight surgeon course. They are responsible for conducting nearly 40% of the annual US Army flight physicals. This unique training and deployment illustrates the growing adaptability of PAs to assume a greater role in military medicine.
December 2016: JAAPA: Official Journal of the American Academy of Physician Assistants
https://www.readbyqxmd.com/read/27894563/administration-of-crofab-antivenom-by-a-helicopter-emergency-medical-service-team
#4
Michael T Steuerwald, Season R K Gabbard, Gillian A Beauchamp, Matthew K Riddle, Edward J Otten
The case presented here highlights an unconventional use of a helicopter emergency medical service (HEMS) to provide a specialized medication to a critically ill patient when definitive transport was delayed. A 39-year-old man presented to a rural hospital 1 hour after sustaining a copperhead envenomation. He developed severe symptoms and was intubated. Arrangements were made for transfer to a tertiary referral center by HEMS, but because of incoming weather conditions, the team would not be able to make the return flight safely...
November 2016: Air Medical Journal
https://www.readbyqxmd.com/read/27894560/analysis-of-temperature-variability-in-medication-storage-compartments-in-emergency-transport-helicopters
#5
Margaret A O'Donnell, Justin Whitfield
The purpose of this study was to determine whether the temperature in medication storage compartments in air medical helicopters was within United States Pharmacopeia (USP)-defined limits for controlled room temperature. This was a prospective study using data obtained from a continuous temperature monitoring device. A total of 4 monitors were placed within 2 medication storage locations in 2 identical helicopters. The data collection period lasted 2 weeks during the summer and winter seasons. Data retrieved from monitors were compared against USP parameters for proper medication storage...
November 2016: Air Medical Journal
https://www.readbyqxmd.com/read/27894558/helicopter-scene-response-for-stroke-patients-a-5-year-experience
#6
Andrew Hawk, Catherine Marco, Matt Huang, Bonnie Chow
OBJECTIVE: The purpose of this study was to examine the usefulness of an emergency medical service (EMS)-requested air medical helicopter response directly to the scene for a patient with clinical evidence of an ischemic cerebrovascular accident (CVA) and transport to a regional comprehensive CVA center. METHODS: CareFlight, an air medical critical care transportation service, is based in Dayton, OH. The 3 CareFlight helicopters are geographically located and provided transport to all CVA scene patients in this study...
November 2016: Air Medical Journal
https://www.readbyqxmd.com/read/27852453/current-use-and-outcomes-of-helicopter-transport-in-pediatric-trauma-a-review-of-18-291-transports
#7
Brian R Englum, Kristy L Rialon, Jina Kim, Mark L Shapiro, John E Scarborough, Henry E Rice, Obinna O Adibe, Elisabeth T Tracy
PURPOSE: The role of helicopter emergency medical services (HEMS) in pediatric trauma remains controversial. We examined its use in pediatric trauma and its effectiveness in children with moderate/severe injuries. METHODS: All blunt/penetrating trauma patients ≤18years old in the National Trauma Data Bank were evaluated for use of HEMS and in-hospital mortality. In a comparative effectiveness study, only patients treated at level I/II pediatric centers with injury severity score (ISS)≥9 were included...
October 27, 2016: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/27843740/verification-of-ribosomal-proteins-of-aspergillus-fumigatus-for-use-as-biomarkers-in-maldi-tof-ms-identification
#8
Sayaka Nakamura, Hiroaki Sato, Reiko Tanaka, Takashi Yaguchi
We have previously proposed a rapid identification method for bacterial strains based on the profiles of their ribosomal subunit proteins (RSPs), observed using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). This method can perform phylogenetic characterization based on the mass of housekeeping RSP biomarkers, ideally calculated from amino acid sequence information registered in public protein databases. With the aim of extending its field of application to medical mycology, this study investigates the actual state of information of RSPs of eukaryotic fungi registered in public protein databases through the characterization of ribosomal protein fractions extracted from genome-sequenced Aspergillus fumigatus strains Af293 and A1163 as a model...
2016: Mass Spectrometry
https://www.readbyqxmd.com/read/27843335/incidence-of-clinical-symptoms-during-long-duration-orbital-spaceflight
#9
Brian Crucian, Adriana Babiak-Vazquez, Smith Johnston, Duane L Pierson, C Mark Ott, Clarence Sams
BACKGROUND: The environment of spaceflight may elevate an astronaut's clinical risk for specific diseases. The purpose of this study was to derive, as accurately as currently possible, an assessment of in-flight clinical "incidence" data, based on observed clinical symptoms in astronauts on board the International Space Station (ISS). METHODS: Electronic medical records were examined from 46 long-duration ISS crew members, each serving approximately a 6-month mission on board the ISS, constituting 20...
2016: International Journal of General Medicine
https://www.readbyqxmd.com/read/27833679/endotracheal-tube-cuff-pressures-in-patients-intubated-prior-to-helicopter-ems-transport
#10
Joseph Tennyson, Tucker Ford-Webb, Stacy Weisberg, Donald LeBlanc
INTRODUCTION: Endotracheal intubation is a common intervention in critical care patients undergoing helicopter emergency medical services (HEMS) transportation. Measurement of endotracheal tube (ETT) cuff pressures is not common practice in patients referred to our service. Animal studies have demonstrated an association between the pressure of the ETT cuff on the tracheal mucosa and decreased blood flow leading to mucosal ischemia and scarring. Cuff pressures greater than 30 cmH2O impede mucosal capillary blood flow...
November 2016: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27826453/effectiveness-of-activated-carbon-masks-in-preventing-anticancer-drug-inhalation
#11
Junya Sato, Atushi Kogure, Kenzo Kudo
BACKGROUND: The exposure of healthcare workers to anticancer drugs such as cyclophosphamide (CPA) is a serious health concern. Anticancer drug pollution may spread outside biological safety cabinets even when a closed system is used. The inhalation of vaporized anticancer drugs is thought to be the primary route of exposure. Therefore, it is important that healthcare workers wear masks to prevent inhalation of anticancer drugs. However, the permeability of medical masks to vaporized anticancer drugs has not been examined...
2016: Journal of Pharmaceutical Health Care and Sciences
https://www.readbyqxmd.com/read/27785661/isolation-of-a-novel-atypical-brucella-strain-from-a-bluespotted-ribbontail-ray-taeniura-lymma
#12
Tobias Eisenberg, Karin Riße, Nicole Schauerte, Christina Geiger, Jochen Blom, Holger C Scholz
A pleomorphic Gram-negative, motile coccobacillus was isolated from the gills of a wild-caught bluespotted ribbontail ray after its sudden death during quarantine. Strain 141012304 was observed to grow aerobically, to be clearly positive for cytochrome oxidase, catalase, urease and was initially identified as "Brucella melitensis" or "Ochrobactrum anthropi" by Matrix-assisted laser desorption/ionization-time of flight mass spectrometry and VITEK2-compact(®), respectively. Affiliation to the genus Brucella was confirmed by bcsp31 and IS711 PCR as well as by Brucella species-specific multiplex PCR, therein displaying a characteristic banding pattern recently described for Brucella strains obtained from amphibian hosts...
October 26, 2016: Antonie Van Leeuwenhoek
https://www.readbyqxmd.com/read/27779958/aeromedical-evaluation-for-an-f-16-candidate-with-incomplete-paraplegia
#13
Monica Chahal-Kummen, Trond-Eirik Strand, Jan Ove Owe, Eigil Gulliksen, Anthony S Wagstaff
BACKGROUND: A candidate with paraplegia contacted the Institute of Aviation Medicine, Oslo, requesting a medical examination and medical certification for flying back seat on an F-16 Fighting Falcon. Thorough aeromedical examinations, including specialist evaluations, were initiated for the final decision to be made. CASE REPORT: Almost 13 yr earlier the candidate had acquired spinal cord damage at neurological level L1 after falling 4 m (13 ft) from out of a window...
2016: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/27779956/emergency-medical-considerations-in-a-space-suited-patient
#14
Alejandro Garbino, Derek M Nusbaum, Daniel M Buckland, Anil S Menon, Jonathan B Clark, Erik L Antonsen
The Stratex Project is a high altitude balloon flight that culminated in a freefall from 41,422 m (135,890 ft), breaking the record for the highest freefall to date. Crew recovery operations required an innovative approach due to the unique nature of the event as well as the equipment involved. The parachutist donned a custom space suit similar to a NASA Extravehicular Mobility Unit (EMU), with life support system mounted to the front and a parachute on the back. This space suit had a metal structure around the torso, which, in conjunction with the parachute and life support assembly, created a significant barrier to extraction from the suit in the event of a medical emergency...
2016: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/27714901/fusaricidins-from-paenibacillus-polymyxa-m-1-a-family-of-lipohexapeptides-of-unusual-complexity-a-mass-spectrometric-study
#15
Joachim Vater, Stefanie Herfort, Joerg Doellinger, Max Weydmann, Kristin Dietel, Sebastian Faetke, Peter Lasch
Paenibacillus polymyxa are rhizobacteria with a high potential to produce natural compounds of biotechnological and medical interest. Main products of P. polymyxa are fusaricidins, a large family of antifungal lipopeptides with a 15-guanidino-3-hydroxypentadecanoic acid (GHPD) as fatty acid side chain. We use the P. polymyxa strain M-1 as a model organism for the exploration of the biosynthetic potential of these rhizobacteria. Using matrix-assisted laser-desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) about 40 new fusaricidins were detected which were fractionated by reversed-phase (rp) HPLC...
October 6, 2016: Journal of Mass Spectrometry: JMS
https://www.readbyqxmd.com/read/27703855/accuracy-of-conventional-identification-methods-used-for-enterobacteriaceae-isolates-in-three-nigerian-hospitals
#16
Christiana Jesumirhewe, Peter Oladejo Ogunlowo, Mitsan Olley, Burkhard Springer, Franz Allerberger, Werner Ruppitsch
BACKGROUND: Enterobacteriaceae are ubiquitously present in nature and can be found in the intestinal tract of humans and animals as commensal flora. Multidrug-resistant Enterobacteriaceae are increasingly reported and are a threat to public health implicating a need for accurate identification of the isolates to species level. In developing countries, identification of bacteria basically depends on conventional methods: culture and phenotypic methods that hamper the accurate identification of bacteria...
2016: PeerJ
https://www.readbyqxmd.com/read/27676126/search-for-plasma-biomarkers-in-drug-free-patients-with-bipolar-disorder-and-schizophrenia-using-metabolome-analysis
#17
Yuki Kageyama, Takaoki Kasahara, Hiromasa Morishita, Nobuko Mataga, Yasuhiko Deguchi, Munehide Tani, Kenji Kuroda, Kotaro Hattori, Sumiko Yoshida, Koki Inoue, Tadafumi Kato
AIM: There is an urgent need for diagnostic biomarkers of bipolar disorder (BD) and schizophrenia (SZ); however, confounding effects of medication hamper biomarker discovery. In this study, we conducted metabolome analyses to identify novel plasma biomarkers in drug-free patients with BD and SZ. METHODS: We comprehensively analyzed plasma metabolites using capillary electrophoresis time-of-flight mass spectrometry in patients with SZ (n = 17), BD (n = 6), and major depressive disorder (n = 9) who had not received psychotropics for at least 2 weeks, and in matched healthy controls (n = 19)...
September 27, 2016: Psychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/27662351/screening-and-mitigation-of-layperson-anxiety-in-aerospace-environments
#18
Robert A Mulcahy, Rebecca S Blue, Johnené L Vardiman, Tarah L Castleberry, James M Vanderploeg
INTRODUCTION: Anxiety may present challenges for commercial spaceflight operations, as little is known regarding the psychological effects of spaceflight on laypersons. A recent investigation evaluated measures of anxiety during centrifuge-simulated suborbital commercial spaceflight, highlighting the potential for severe anxiousness to interrupt spaceflight operations. METHODS: To pave the way for future research, an extensive literature review identified existing knowledge that may contribute to formation of interventions for anxiety in commercial spaceflight...
2016: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/27662348/prognostic-factors-for-outcomes-of-in-flight-sudden-cardiac-arrest-on-commercial-airlines
#19
Paulo M Alves, Charles A DeJohn, Eduard M Ricaurte, William D Mills
BACKGROUND: In-flight cardiac arrest (IFCA) is a relatively rare but challenging event. Outcomes and prognostic factors are not entirely understood for victims of IFCAs in commercial aviation. METHODS: This was a retrospective cohort study of airline passengers who experienced IFCA. Demographic and operational variables were studied to identify association in a multivariate logistic regression model with the outcome of survival-to-hospital. In-flight medical emergencies were processed by a ground-based medical center...
2016: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/27661389/tof-sims-and-laser-snms-imaging-of-heterogeneous-topographically-complex-polymer-systems
#20
Andreas Pelster, Martin Körsgen, Takako Kurosawa, Hiromi Morita, Heinrich F Arlinghaus
Heterogeneous polymer coatings, such as those used in organic electronics and medical devices, are of increasing industrial importance. In order to advance the development of these types of systems, analytical techniques are required which are able to determine the elemental and molecular spatial distributions, on a nanometer scale, with very high detection efficiency and sensitivity. The goal of this study was to investigate the suitability of laser postionization secondary neutral mass spectrometry (Laser-SNMS) with a 157 nm postionization laser beam to image structured polymer mixtures and compare the results with time-of-flight secondary ion mass spectrometry (ToF-SIMS) measurements using Bi3(+) primary ions...
October 4, 2016: Analytical Chemistry
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