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Pediatric allergy

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https://www.readbyqxmd.com/read/28099424/the-establishment-of-cow-s-milk-protein-allergy-in-infants-is-related-with-a-deficit-of-regulatory-t-cells-treg-and-vitamin-d
#1
Laura Perezabad García, Jacobo López-Abente Muñoz, Elena Alonso-Lebrero, Elena Seoane Reula, Marjorie Pion, Rafael Correa-Rocha
BACKGROUND: Cow's milk protein allergy (CMPA) is the most common food allergy in infants. However, little is known about which specific immune mechanisms are related with the CMPA onset. The objective was to investigate which immune alterations constitute differential factors between allergy and tolerance, and hence could be implicated in the CMPA establishment in infants. METHODS: An extensive analysis of immune subsets, including Treg and cytokine-secreting cells was performed in blood samples from 28 infants younger than 9 months obtained 1-4 days after the first adverse reaction to milk...
January 18, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28094121/mealtime-behavior-among-parents-and-their-young-children-with-food-allergy
#2
Linda Jones Herbert, Priya Mehta, Hemant Sharma
BACKGROUND: Food allergies are increasingly prevalent in the pediatric population. Balancing allergen avoidance with the promotion of healthy eating behaviors can be challenging for families. OBJECTIVE: To characterize mealtime behaviors among parents of young children with food allergy. METHODS: Seventy-four parents of young children with food allergies (≤7 years of age) completed measures of mealtime behavior, perceptions of food allergy risk and severity, pediatric parenting stress, and food allergy-related quality of life...
January 13, 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28078865/parasympathetic-nervous-system-involvement-in-food-allergy-description-of-a-paediatric-case
#3
G Vitaliti, P Pavone, G R Giugno, M Vecchio, S Cocuzza, A Serra, L Maiolino, P Di Mauro, R Lubrano, R Falsaperla
The latest research data emphasize the interaction between the nervous and the immune systems. It has been demonstrated that the central nervous system (CNS) can be involved secondarily due to blood brain barrier (BBB) disruption via pro-inflammatory cytokines released in allergy. More recently it was demonstrated that the parasympathetic nervous system (PNS) could also be equally involved in models of peripheral inflammation such as food allergy; although this last clinical presentation has rarely been described...
October 2016: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28077121/awareness-of-food-allergies-a-survey-of-pediatricians-in-kuwait
#4
Waleed Al-Herz, Khalid Husain, Ahmed Al-Khabaz, Mohamed A A Moussa, Fawaz Al-Refaee
BACKGROUND: Early diagnosis of food allergies (FA) is important for a favorable prognosis. This study aimed to determine the level of awareness of FA among pediatricians in Kuwait. METHOD: A 43-item self-administered questionnaire was designed and distributed to pediatricians working at 4 government hospitals in Kuwait. RESULTS: A total of 140 pediatricians completed the questionnaire, with a participation rate of 51.1% (81 males and 59 females)...
January 11, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28076664/sensitization-predicts-asthma-development-among-wheezing-toddlers-in-secondary-healthcare
#5
Nienke A Boersma, Ruud W H Meijneke, Johannes C Kelder, Cornelis K van der Ent, Walter A F Balemans
INTRODUCTION: Some wheezing toddlers develop asthma later in childhood. Sensitization is known to predict asthma in birth cohorts. However, its predictive value in secondary healthcare is uncertain. AIM: This study examines the predictive value of sensitization to inhalant allergens among wheezing toddlers in secondary healthcare for the development of asthma at school age (≥6 years). METHODS: Preschool children (1-3 years) who presented with wheezing in secondary healthcare were screened on asthma at school age with the International Study of Asthma and Allergies in Childhood questionnaire...
January 11, 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/28045551/use-of-a-low-literacy-written-action-plan-to-improve-parent-understanding-of-pediatric-asthma-management-a-randomized-controlled-study
#6
Hsiang Shonna Yin, Ruchi Gupta, Alan L Mendelsohn, Benard P Dreyer, Linda van Schaick, Christina R Brown, Karen Encalada, Dayana Sanchez, Christopher Warren, Suzy Tomopoulos
OBJECTIVES: To determine whether parents who use a low literacy, pictogram- and photograph-based written asthma action plan have a better understanding of child asthma management compared to parents using a standard plan. METHODS: Randomized controlled study in 2 urban pediatric outpatient clinics. INCLUSION CRITERIA: English/Spanish-speaking parents of 2-12 year old asthmatic children. Parents were randomized to receive a low literacy or standard asthma action plan (American Academy of Allergy, Asthma and Immunology) for a hypothetical patient on controller and rescue medications...
January 3, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28042527/pediatric-rhinosinusitis
#7
Dana T Badr, Jonathan M Gaffin, Wanda Phipatanakul
Rhinosinusitis, is defined as an inflammation of the paranasal and nasal sinus mucosae. Chronic rhinosinusitis (CRS)is a common problem in the pediatric age group and the diagnosis and treatment are challenging due to the chronicity and similarity of symptoms with allergic rhinitis and adenoid hypertrophy. Although it is less common than acute rhinosinusitis, CRS is becoming more frequent and significantly affects the quality of life in children and can substantially impair daily function. CRS is characterized by sinus symptoms lasting more than 3 months despite medical therapy...
September 2016: Current Treatment Options in Allergy
https://www.readbyqxmd.com/read/28042003/the-prevalence-of-eosinophilic-esophagitis-in-pediatric-patients-with-ige-mediated-food-allergy
#8
David A Hill, Jesse W Dudley, Jonathan M Spergel
BACKGROUND: Eosinophilic esophagitis (EoE) is an allergic inflammatory disease that is triggered by food allergens and characterized by progressive esophageal dysfunction. Recently, EoE has been identified in patients who underwent oral immunotherapy (OIT) for IgE-mediated food allergy, suggesting an association. OBJECTIVE: We sought to ascertain whether significant associations exist between IgE-mediated food allergies and EoE. METHODS: Using the analysis of electronic medical record data and manual chart review, we examined our subspecialty care network of 35,528 children and adolescents to identify and characterize patients with IgE-mediated and EoE food allergy...
December 30, 2016: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28025415/japanese-pediatric-guideline-for-food-allergy-2016-how-to-prevent-complete-avoidance
#9
Motohiro Ebisawa
No abstract text is available yet for this article.
2016: Arerugī, [Allergy]
https://www.readbyqxmd.com/read/28025241/clinical-tools-to-assess-asthma-control-in-children
#10
Chitra Dinakar, Bradley E Chipps
Asthma affects an estimated 7 million children and causes significant health care and disease burden. The most recent iteration of the National Heart, Lung and Blood Institute asthma guidelines, the Expert Panel Report 3, emphasizes the assessment and monitoring of asthma control in the management of asthma. Asthma control refers to the degree to which the manifestations of asthma are minimized by therapeutic interventions and the goals of therapy are met. Although assessment of asthma severity is used to guide initiation of therapy, monitoring of asthma control helps determine whether therapy should be maintained or adjusted...
January 2017: Pediatrics
https://www.readbyqxmd.com/read/28002520/clinical-immunological-and-pathological-profile-of-infants-suffering-from-cow-s-milk-protein-allergy
#11
Elena Tătăranu, Smaranda Diaconescu, Camelia Geanina Ivănescu, Ioan Sârbu, Maria Stamatin
Cow's milk protein allergy (CMPA) is the most frequently encountered form of food allergy in pediatric patients and occurs secondary to cow's milk proteins (CMP) ingestion. The aim of this study is to define the profile of children suffering from CMPA and to describe the associated pathological findings. The authors performed a retrospective case-control study on 160 infants that presented with CMPA symptoms at "Sf. Maria" Emergency Clinical Hospital for Children, Iassy, Romania, between January 2013 and January 2015...
2016: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/27998193/update-on-dietary-therapy-for-eosinophilic-esophagitis-in-children-and-adults
#12
Javier Molina-Infante, Pedro Luis Gonzalez-Cordero, Angel Arias, Alfredo J Lucendo
Eosinophilic esophagitis (EoE) is a chronic inflammatory esophageal disease triggered predominantly, but not excusively, by food antigens. Elimination diet thus remains the only therapy targeting the cause of the disease. Importantly, EoE is a unique form of non-IgE mediated food allergy, largely dependant upon delayed, cell-mediated hypersensitivity. Areas covered: A comprehensive review of literature to summarize and update the most relevant advances on dietary therapy for pediatric and adult EoE patients is conducted...
December 23, 2016: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/27993248/-probable-mental-health-disorders-prevalence-in-children-with-chronic-conditions-results-from-the-national-mental-health-survey-of-colombia-2015
#13
Carlos Gómez-Restrepo, Sandra Ramirez, Nathalie Tamayo Martínez, Maria Nelcy Rodriguez, Andrea Rodríguez, Henrey Rengifo
INTRODUCTION: The prevalence of chronic conditions is increasing globally and this phenomenon covers pediatric populations. There is a relationship between chronic conditions and mental health problems, which has been insufficiently studied in the case of children. OBJECTIVE: To measure the frequency of problems and mental disorders in the Colombian population between 7 and 11 years, depending on the presence or absence of chronic conditions. METHODS: The information pertains to the National Survey of Mental Health of Colombia 2015, an observational cross-sectional nationally representative for the group between 7 and 11 years old...
December 2016: Revista Colombiana de Psiquiatría
https://www.readbyqxmd.com/read/27966312/the-common-genetic-variants-of-toll-like-receptor-and-susceptibilityto-adenoid-hypertrophy-a-hospital-based-cohort-study
#14
Mehmet Ali Babademez, Talih Özdaş, Sibel Özdaş
BACKGROUND/AIM: Adenoid hypertrophy (AH) is one of the most frequent pediatric disorders. The aim of this study was to investigate the effects of TLR2-R753Q, TLR4-T399I, and TLR4-D299G polymorphisms in children with AH. MATERIALS AND METHODS: The variants of the TLR gene were determined by restriction fragment length polymorphism (PCR-RFLP) analysis in 60 patients with AH and in 50 healthy children. Data were analyzed with SNPStats and multifactor dimensionality reduction (MDR) software...
November 17, 2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/27956906/prevalence-of-beta-lactam-allergy-a-retrospective-chart-review-of-drug-allergy-assessment-in-a-predominantly-pediatric-population
#15
Elissa M Abrams, Andrew Wakeman, Tom V Gerstner, Richard J Warrington, Alexander G Singer
BACKGROUND: Research suggests that 90% of patients labeled beta-lactam allergic are able to tolerate penicillins following further assessment. This study aims to define and describe the frequency of true beta-lactam allergy following allergy patient evaluation in a predominantly pediatric population. METHODS: 306 primary care patients referred between January 2010 and June 2015 were assessed for a suspected beta-lactam allergy. Patient demographics, history and test results were extracted from electronic medical records...
2016: Allergy, Asthma, and Clinical Immunology
https://www.readbyqxmd.com/read/27940791/indoor-environmental-control-practices-and-asthma-management
#16
Elizabeth C Matsui, Stuart L Abramson, Megan T Sandel
Indoor environmental exposures, particularly allergens and pollutants, are major contributors to asthma morbidity in children; environmental control practices aimed at reducing these exposures are an integral component of asthma management. Some individually tailored environmental control practices that have been shown to reduce asthma symptoms and exacerbations are similar in efficacy and cost to controller medications. As a part of developing tailored strategies regarding environmental control measures, an environmental history can be obtained to evaluate the key indoor environmental exposures that are known to trigger asthma symptoms and exacerbations, including both indoor pollutants and allergens...
November 2016: Pediatrics
https://www.readbyqxmd.com/read/27940693/use-of-food-allergy-panels-by-pediatric-care-providers-compared-with-allergists
#17
David R Stukus, Erin Kempe, Amy Leber, David Thornton, Rebecca Scherzer
BACKGROUND AND OBJECTIVE: Immunoglobullin E (IgE)-mediated food allergies affect 5% to 8% of children. Serum IgE levels assist in diagnosing food allergies but have low positive predictive value. This can lead to misinterpretation, overdiagnosis, and unnecessary dietary elimination. Use of IgE food allergen panels has been associated with increased cost and burden. The scale of use of these panels has not been reported in the medical literature. METHODS: We conducted a retrospective review of a commercial laboratory database associated with a tertiary care pediatric academic medical center for food IgE tests ordered by all provider types during 2013...
December 2016: Pediatrics
https://www.readbyqxmd.com/read/27931294/long-term-outcome-after-pediatric-intensive-care-unit-asthma-admissions
#18
Ibrahim Abu-Kishk, Sharon Polakow-Farkash, Arnon Elizur
BACKGROUND: Patients with asthma admitted to the pediatric intensive care unit (PICU) are often found to have had previous severe asthma exacerbations. OBJECTIVE: To prospectively evaluate the outcome of children after PICU admission. METHODS: Patients, ages 218 years, admitted to the PICU at Assaf Harofeh Medical Center over a 10-year period were assessed at a mean of 10 years after their admission and compared with matched patients admitted to the pediatric ward...
November 2016: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/27931280/safety-profile-of-oral-immunotherapy-with-cows-milk-and-hen-egg-a-10-year-experience-in-controlled-trials
#19
Giovanni B Pajno, Lucia Caminiti, Fernanda Chiera, Giuseppe Crisafulli, Giuseppina Salzano, Stefania Arasi, Giovanni Passalacqua
BACKGROUND: Oral immunotherapy (OIT) for food allergy is gaining interest due to the favorable clinical results reported with cow's milk, hen egg and peanut. The safety of the procedure remains a critical aspect that can limit the introduction of OIT in clinical practice. OBJECTIVE: We described herein, in detail, the occurrence and characteristics of adverse events (AE) with OIT in children who participated in controlled trials at our unit. METHODS: The clinical records of 68 children who received active treatment (40 for cow's milk and 28 for hen egg) were carefully reviewed...
September 2016: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/27923649/food-allergy-trends-and-epinephrine-autoinjector-presence-in-summer-camps
#20
Natalie R Schellpfeffer, Harvey L Leo, Michael Ambrose, Andrew N Hashikawa
BACKGROUND: Pediatric campers with food allergies are at greater risk for exposure and anaphylaxis. A diagnosis of asthma increases risk for anaphylaxis. Epidemiological investigations of food-allergic children at high risk for allergic reactions requiring intervention in camp settings are lacking. OBJECTIVE: The objectives of this study were to estimate the prevalence of food allergies among otherwise healthy campers in summer camps throughout the United States and Canada, and to assess asthma comorbidity and determine rates of epinephrine autoinjector prescriptions present in this population...
December 3, 2016: Journal of Allergy and Clinical Immunology in Practice
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