Read by QxMD icon Read


Ana Beatriz De Abajo Larriba, Ángel Díaz Rodríguez, Javier González-Gallego, Beatriz Peleteiro Cobo, Jessica Capón Álvarez, Omar Mahmoud Atoui, Enrique Méndez Rodríguez, Serafín De Abajo Olea, Víctor Lumbreras González, Caterina Minniti
Objetivos: estimar las actividades preventivas que realizan los pacientes diagnosticados de enfermedad pulmonar obstructiva crónica (EPOC) en la provincia de León.Métodos: estudio epidemiológico, transversal, multicéntrico (30 centros de salud de la provincia de León). Incluyó pacientes mayores de 35 años diagnosticados y tratados de EPOC. Variables a estudio: edad, sexo, hábitat, datos antropométricos, tabaquismo, estado nutricional, ejercicio físico, vacunación antigripal, vacunación, antineumocócica (VNP23 y VNC13), fenotipo, gravedad, reagudizaciones y hospitalizaciones...
September 20, 2016: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
Jiayin Fu, Changjiang Fan, Wei Shan Lai, Dongan Wang
The transport of nutrients and oxygen by vascular networks into engineered tissue constructs is critical to their successful integration into host tissues. Hydrogel has achieved some promising results as scaffolds for vascularization. However, the vascularization of hydrogel is still constrained by its inherent submicron- or nano-sized pores. In this study, two gelatin-based micro-cavitary gel (Gel-MCG) constructs with varying densities of micro-cavities were developed with a photocrosslinkable gelatin methacrylate (Gel-MA) precursor and porogenic gelatin microspheres (MS), and their functions in supporting vascularization within hydrogels were evaluated with endothelial progenitor outgrowth cells (EPOCs)...
October 7, 2016: Biomedical Materials
Swantje Völler, Georg Hempel, Gudrun Würthwein, Alan V Boddy, Miriam Krischke, Nicolas André, Maurizio D'Incalci, Gianni Bisogno, Joachim Boos
Following the publication of our paper regarding a population-based model of doxorubicin pharmacokinetics in children in Clinical Pharmacokinetics last year (Voller et al. 54:1139-1149, 2015), we have received many inquiries on the practical clinical consequences of this model; however, a population-based model is only one of the aspects to be taken into account when developing dosing algorithms. In addition, any new method of dose calculation would need clinical validation and, subsequently, a new clinical trial...
September 19, 2016: Clinical Pharmacokinetics
Sasha Shepperd, Steve Iliffe, Helen A Doll, Mike J Clarke, Lalit Kalra, Andrew D Wilson, Daniela C Gonçalves-Bradley
BACKGROUND: Admission avoidance hospital at home provides active treatment by healthcare professionals in the patient's home for a condition that otherwise would require acute hospital inpatient care, and always for a limited time period. This is the third update of the original review. OBJECTIVES: To determine the effectiveness and cost of managing patients with admission avoidance hospital at home compared with inpatient hospital care. SEARCH METHODS: We searched the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, EMBASE, two other databases, and two trials registers on 2 March 2016...
September 1, 2016: Cochrane Database of Systematic Reviews
Ana Beatriz De Abajo Larriba, Ángel Díaz Rodríguez, Javier González-Gallego, Enrique Méndez Rodríguez, María Jesús Álvarez Álvarez, Jessica Capón Álvarez, Beatriz Peleteiro Cobo, Omar Mahmoud Atoui, Serafín De Abajo Olea, Juan Martínez de Mandojana Hernández
Introducción: estimar la prevalencia del tabaquismo y analizar cómo se diagnostican y se trata a los fumadores diagnosticados de EPOC.Métodos: estudio epidemiológico, transversal, multicéntrico (30 centros salud de la provincia de León). Incluyó pacientes mayores de 35 años diagnosticados y tratados de EPOC. Variables analizadas: edad, sexo, hábitat, datos antropométricos, tabaquismo, número de paquetes/año, cooximetría, dependencia (escala analógico-visual), motivación (test de Fagerström), autoeficacia, estado anímico, intentos previos, terapia cognitivo-conductual, tratamiento farmacológico (TSN, bupropión, vareniclina) y recaídas...
2016: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
Hamish Graham, Mariam Tokhi, Trevor Duke
OBJECTIVES: To identify and review strategies of providing care for children living with chronic health conditions in low- and middle-income countries. METHODS: We searched MEDLINE and Cochrane EPOC databases for papers evaluating strategies of providing care for children with chronic health conditions in low- or middle-income countries. Data were systematically extracted using a standardised data charting form, and analysed according to Arksey and O'Malley's 'descriptive analytical method' for scoping reviews...
August 24, 2016: Tropical Medicine & International Health: TM & IH
Gerd Flodgren, Amanda M Hall, Lucy Goulding, Martin P Eccles, Jeremy M Grimshaw, Gillian C Leng, Sasha Shepperd
BACKGROUND: The uptake of clinical practice guidelines (CPGs) is inconsistent, despite their potential to improve the quality of health care and patient outcomes. Some guideline producers have addressed this problem by developing tools to encourage faster adoption of new guidelines. This review focuses on the effectiveness of tools developed and disseminated by guideline producers to improve the uptake of their CPGs. OBJECTIVES: To evaluate the effectiveness of implementation tools developed and disseminated by guideline producers, which accompany or follow the publication of a CPG, to promote uptake...
2016: Cochrane Database of Systematic Reviews
Philip R A Baker, Daniel P Francis, Noran N Hairi, Sajaratulnisah Othman, Wan Yuen Choo
BACKGROUND: Maltreatment of older people (elder abuse) includes psychological, physical, sexual abuse, neglect and financial exploitation. Evidence suggests that 10% of older adults experience some form of abuse, and only a fraction of cases are actually reported or referred to social services agencies. Elder abuse is associated with significant morbidity and premature mortality. Numerous interventions have been implemented to address the issue of elder maltreatment. It is, however, unclear which interventions best serve to prevent or reduce elder abuse...
2016: Cochrane Database of Systematic Reviews
Christopher Plishka, Thomas Rotter, Leigh Kinsman, Mohammed Rashaad Hansia, Adegboyega Lawal, Donna Goodridge, Erika Penz, Darcy D Marciniuk
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a respiratory syndrome characterized by progressive, partially reversible airway obstruction and lung hyperinflation. COPD has a substantial burden which is seen in both patient quality of life and healthcare costs. One proposed method of minimizing this burden is the implementation of clinical pathways (CPWs). CPWs aim to guide evidence-based practice and improve the interaction between health services. They bring the best available evidence to a range of healthcare professionals by adapting evidence-based clinical guidelines to a local context and detailing the essential steps in the assessment and care of patients...
2016: Systematic Reviews
Hany Abdel-Aleem, Omaima M H El-Gibaly, Amira F E-S El-Gazzar, Ghada S T Al-Attar
BACKGROUND: The accessibility of health services is an important factor that affects the health outcomes of populations. A mobile clinic provides a wide range of services but in most countries the main focus is on health services for women and children. It is anticipated that improvement of the accessibility of health services via mobile clinics will improve women's and children's health. OBJECTIVES: To evaluate the impact of mobile clinic services on women's and children's health...
2016: Cochrane Database of Systematic Reviews
Charles S Wiysonge, Leila H Abdullahi, Valantine N Ndze, Gregory D Hussey
BACKGROUND: Governments use different approaches to ensure that private for-profit healthcare services meet certain quality standards. Such government guidance, referred to as public stewardship, encompasses government policies, regulatory mechanisms, and implementation strategies for ensuring accountability in the delivery of services. However, the effectiveness of these strategies in low- and middle-income countries (LMICs) have not been the subject of a systematic review. OBJECTIVES: To assess the effects of public sector regulation, training, or co-ordination of the private for-profit health sector in low- and middle-income countries...
2016: Cochrane Database of Systematic Reviews
Kristian Karstoft, Gareth A Wallis, Bente K Pedersen, Thomas P J Solomon
BACKGROUND: For unknown reasons, interval training often reduces body weight more than energy-expenditure matched continuous training. We compared the acute effects of time-duration and oxygen-consumption matched interval- vs. continuous exercise on excess post-exercise oxygen consumption (EPOC), substrate oxidation rates and lipid metabolism in the hours following exercise in subjects with type 2 diabetes (T2D). METHODS: Following an overnight fast, ten T2D subjects (M/F: 7/3; age=60...
September 2016: Metabolism: Clinical and Experimental
Heinz Diehl, Birgitte Graverholt, Birgitte Espehaug, Hans Lund
BACKGROUND: Research on guideline implementation strategies has mostly been conducted in settings which differ significantly from a nursing home setting and its transferability to the nursing home setting is therefore limited. The objective of this study was to systematically review the effects of interventions to improve the implementation of guidelines in nursing homes. METHODS: A systematic literature search was conducted in the Cochrane Library, CINAHL, Embase, MEDLINE, DARE, HTA, CENTRAL, SveMed + and ISI Web of Science from their inception until August 2015...
2016: BMC Health Services Research
Siân A Pugh, Megan Bowers, Alexandre Ball, Stephen Falk, Meg Finch-Jones, Juan W Valle, Derek A O'Reilly, Ajith K Siriwardena, Joanne Hornbuckle, Myrddin Rees, Charlotte Rees, Tim Iveson, Tamas Hickish, Tom Maishman, Louise Stanton, Elizabeth Dixon, Andrea Corkhill, Mike Radford, O James Garden, David Cunningham, Tim S Maughan, John A Bridgewater, John N Primrose
BACKGROUND: The addition of cetuximab (CTX) to perioperative chemotherapy (CT) for operable colorectal liver metastases resulted in a shorter progression-free survival. Details of disease progression are described to further inform the primary study outcome. METHODS: A total of 257 KRAS wild-type patients were randomised to CT alone or CT with CTX. Data regarding sites and treatment of progressive disease were obtained for the 109 (CT n=48, CT and CTX n=61) patients with progressive disease at the cut-off date for analysis of November 2012...
August 9, 2016: British Journal of Cancer
Angela Oyo-Ita, Charles S Wiysonge, Chioma Oringanje, Chukwuemeka E Nwachukwu, Olabisi Oduwole, Martin M Meremikwu
BACKGROUND: Immunisation is a powerful public health strategy for improving child survival, not only by directly combating key diseases that kill children but also by providing a platform for other health services. However, each year millions of children worldwide, mostly from low- and middle-income countries (LMICs), do not receive the full series of vaccines on their national routine immunisation schedule. This is an update of the Cochrane review published in 2011 and focuses on interventions for improving childhood immunisation coverage in LMICs...
2016: Cochrane Database of Systematic Reviews
David Bardell, Eleanor West, J Mark Senior
OBJECTIVES: To determine whether the Enterprise point-of-care blood analysis system (EPOC) produces results in agreement with two other blood gas analysers in regular clinical use (i-STAT and Radiometer ABL77) and to investigate the precision of the new machine when used with equine whole blood. STUDY DESIGN: Prospective, randomized, non-blinded, comparative laboratory analyser study. ANIMALS: Horses admitted to a university teaching hospital requiring arterial or venous blood gas analysis as part of their routine clinical management...
July 7, 2016: Veterinary Anaesthesia and Analgesia
Tarun Gera, Dheeraj Shah, Paul Garner, Marty Richardson, Harshpal S Sachdev
BACKGROUND: More than 7.5 million children younger than age five living in low- and middle-income countries die every year. The World Health Organization (WHO) developed the integrated management of childhood illness (IMCI) strategy to reduce mortality and morbidity and to improve quality of care by improving the delivery of a variety of curative and preventive medical and behavioral interventions at health facilities, at home, and in the community. OBJECTIVES: To evaluate the effects of programs that implement the IMCI strategy in terms of death, nutritional status, quality of care, coverage with IMCI deliverables, and satisfaction of beneficiaries...
2016: Cochrane Database of Systematic Reviews
Wenyan Leong, Changjiang Fan, Dong-An Wang
Hydrogels have been widely regarded as promising tissue engineering scaffolds and cell delivery vehicles, however, their inherent submicron- or nano-scale polymer networks severely inhibit the settlement of anchorage dependent cells (ADCs). Here, using endothelial progenitor outgrowth cells (EPOCs) as the typical ADCs, a gelatin-based micro-cavitary gel (namely Gel-MCG) is developed with gelatin-methacrylate and gelatin microspheres as precursor and porogens, respectively, to promote cellular focal adhesion and functions...
October 1, 2016: Colloids and Surfaces. B, Biointerfaces
Rachel Simmons, David P Swain
No abstract text is available yet for this article.
May 2016: Medicine and Science in Sports and Exercise
Katsunori Tsuji, Yuzhong Xu, Izumi Tabata
No abstract text is available yet for this article.
May 2016: Medicine and Science in Sports and Exercise
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"