keyword
MENU ▼
Read by QxMD icon Read
search

NPH

keyword
https://www.readbyqxmd.com/read/29129431/ultra-rapid-catalytic-degradation-of-4-nitrophenol-with-ionic-liquid-recoverable-and-reusable-ibuprofen-derived-silver-nanoparticles
#1
Syeda Sara Hassan, Krista Carlson, Swomitra Kumar Mohanty, Sirajuddin, Ali Canlier
This study reports a one-pot and eco-friendly method for the synthesis of spherical ibuprofen derived silver nanoparticles (IBU-AgNPs) in aqueous media using ibuprofen analgesics drug as capping as well as reducing agent. Formation of AgNPs occurred within a few min (less than 5 min) at room temperature without resorting to any harsh conditions and hazardous organic solvents. Synthesized AgNPs were characterized with common analytical techniques. Transmission electron microscope (TEM) images confirmed the formation of spherical particles having a size distribution in the range of 12...
November 9, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/29109063/normal-pressure-hydrocephalus-shunt-patients-have-fewer-complications-than-other-shunt-patients
#2
Pascale Schenker, Lennart Stieglitz, Beate Sick, Martin N Stienen, Luca Regli, Johannes Sarnthein
BACKGROUND: Ventriculoperitoneal (VP) shunting is a well-established therapy for hydrocephalus. However, complications are frequent. The incidence of idiopathic normal pressure hydrocephalus (NPH) rises with the aging of the population. We evaluated the functional status of patients and the classification of complications associated with VP shunt procedures in our center. METHODS: We recorded all VP-shunt procedures in our prospective patient registry from January 2013 to December 2015...
November 3, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29103634/efficacy-of-endoscopic-third-ventriculostomy-in-old-aged-patients-with-normal-pressure-hydrocephalus
#3
Young Sill Kang, Eun-Kyung Park, Ju-Seong Kim, Dong-Seok Kim, Ulrich-Wilhelm Thomale, Kyu-Won Shim
Normal pressure hydrocephalus (NPH) is a chronic disorder caused by interrupted CSF absorption or flow. Generally, shunt placement is first option for NPH treatment. Due to complications of ventriculo-peritoneal (VP) shunt placement, endoscopic third ventriculostomy (ETV) can be considered as an alternative treatment option. Here we report the efficacy of ETV especially in old aged patients with normal pressure hydrocephalus. Total 21 old aged patients with communicating hydrocephalus with opening pressure, measured via lumbar puncture, less than 20cm H2O underwent ETV...
October 23, 2017: Neurologia i Neurochirurgia Polska
https://www.readbyqxmd.com/read/29090977/observational-registry-of-basal-insulin-treatment-in-patients-with-type-2-diabetes-in-china-safety-and-hypoglycemia-predictors
#4
Tingting Zhang, Linong Ji, Yan Gao, Puhong Zhang, Dongshan Zhu, Xian Li, Jiachao Ji, Fang Zhao, Heng Zhang, Xiaohui Guo
BACKGROUND: The Observational Registry of Basal Insulin Treatment (ORBIT) study evaluated the safety of basal insulin (BI) in real-world settings in China. METHODS: We analyzed 9002 patients with type 2 diabetes (T2D) inadequately controlled with oral hypoglycemic agents from 8 geographic regions and 2 hospital tiers in China who initiated and maintained BI treatment. Body weight and hypoglycemic episodes were recorded at baseline and 3 and 6 months. Serious adverse events (SAEs) were recorded at 3 and 6 months...
November 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/29067264/outpatient-management-of-steroid-induced-hyperglycaemia-and-steroid-induced-diabetes-in-people-with-lymphoproliferative-disorders-treated-with-intermittent-high-dose-steroids
#5
Jennifer Vidler, Charlotte Rogers, Deborah Yallop, Stephen Devereux, Ellinor Wellving, Orla Stewart, Alison Cox, Katharine F Hunt, Shireen Kassam
High dose steroids (HDS) are used in the treatment of haematological malignancies. The reported risk of steroid-induced diabetes (SID) is high. However, screening is not consistently performed. We implemented a protocol for detection and management of SID and steroid-induced hyperglycamia (SIH) in haematology outpatients receiving HDS. Eighty-three people were diagnosed with a lymphoproliferative disorder, of whom 6 had known Type 2 diabetes. Fifty-three people without known diabetes were screened by HbA1c and random venous plasma glucose...
September 2017: Journal of Clinical & Translational Endocrinology
https://www.readbyqxmd.com/read/29058748/experimental-and-mechanistic-insights-into-copper-ii-dioxygen-catalyzed-oxidative-n-dealkylation-of-n-2-pyridylmethyl-phenylamine-and-its-derivatives
#6
Yang Wang, Haixiong Liu, Xiaofeng Zhang, Zilong Zhang, Deguang Huang
A di-(2-pyridylmethyl)phenylamine ((PyCH2)2NPh) supported Cu(ii)/O2 catalytic system was explored with the synthesis of pyridylmethyl-based compounds of carboxylate (PyCOOH), amide (PyC(O)NHPh), and imine (PyCH[double bond, length as m-dash]NPh) from the oxidative N-dealkylation of N-(2-pyridylmethyl)phenylamine (PyCH2NHPh) and its derivatives, by means of controlling the addition of a base and/or water to the reaction system under a dioxygen atmosphere at room temperature. Experimental studies showed that the imine and amide species could be precursors in succession in the way to the final oxidation state of carboxylates...
November 7, 2017: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/29055384/the-central-nervous-system-pressure-histogram-in-hydrocephalus-and-hydromyelia
#7
H F Williams
This work makes proposals on the relationship between intracranial pressure (ICP) and hydrocephalus that changes over time with the evolution of the disease. This includes the cerebrospinal fluid (CSF) filling mechanism that leads to an increase in mode pressure if excess fluid volume exacerbates the obstructive process. Elevation in mode occurs because pressure in the central nervous system (CNS) represents a state of reduced flow, rather than an abnormality of volume. Diseases that cause elevated mode pressure by means of a primary edema can lead to hydrocephalus if there is sufficient time and obstruction to flow for the filling mechanism to act...
October 2017: Medical Hypotheses
https://www.readbyqxmd.com/read/29044816/zinc-catalyzed-hydrosilylation-copolymerization-of-aromatic-dialdehydes-with-diphenylsilane
#8
Chuanyang Li, Xiufang Hua, Zehuai Mou, Xinli Liu, Dongmei Cui
The hydrosilylation reaction of diphenylsilane and phthalaldehyde is catalyzed by heteroscorpionate zinc hydride complex LZnH (1, L = ((Me) Pz)2 CP(Ph)2 NPh, (Me) Pz = 3,5-dimethylpyrazolyl). Both terephthalaldehyde (tPAA) and isophthalaldehyde (iPAA) affords linear polymer; however, when PAA is used, a seven-membered cyclic silyl ether is formed. These products are characterized by (1) H and (13) C NMR spectra. Other properties of polymers are determined by gel permeation chromatography (GPC)-multiangle laser-light scattering, differential scanning calorimetry, and thermogravimetry...
October 17, 2017: Macromolecular Rapid Communications
https://www.readbyqxmd.com/read/29044018/-insulin-therapy-in-special-conditions
#9
León E Litwak, Alicia Elbert, Cristina Faingold, Luis A Grosembacher, Adrián Proietti, Félix Puchulu
Hyperglycemia during hospitalization is a common condition associated with poor prognosis. To date, insulin is the best strategy to treat hyperglycemia in these patients. An adequate glycemic control is associated with better clinical results. Nevertheless, glycemic goals are still controversial due to the increase of hypoglycemia and other adverse events. Diabetes mellitus is still the main cause of chronic renal failure in our country and its treatment deserves a special analysis considering that insulin pharmacokinetics is altered...
2017: Medicina
https://www.readbyqxmd.com/read/29032075/synthesis-structures-and-esi-mass-studies-of-silver-i-derivatives-of-imidazolidine-2-thiones-antimicrobial-potential-and-biosafety-evaluation
#10
Jaspreet K Aulakh, Tarlok S Lobana, Henna Sood, Daljit S Arora, Victoria A Smolinski, Courney E Duff, Jerry P Jasinski
The basic objective of this investigation is to explore potential metallo-organic antimicrobial agents based on silver-heterocyclic-2-thiones. In this respect, a series of silver(I) halide complexes with imidazolidine-2-thiones (L-NR, R=H, Me, Et, Pr(n), Bu(n), Ph), namely, mononuclear [AgX(L-NR)(PPh3)2] (X, R: Cl, Bu, 1; Br, Ph, 7); [AgX(L-NR)3] (Br, Bu, 5; Br, Pr(n), 8) and halogen bridged dinuclear [Ag2(μ-X)2(L-NR)2(PPh3)2] (Cl, Bu(n), 2; Cl, Ph, 3; Cl, Pr(n), 4; Br, Ph, 6) have been synthesized and characterized using modern techniques...
October 7, 2017: Journal of Inorganic Biochemistry
https://www.readbyqxmd.com/read/29017173/insulin-regimens-to-treat-hyperglycemia-in-hospitalized-patients-on-nutritional-support-systematic-review-and-meta-analyses
#11
Marina Verçoza Viana, Luciana Verçoza Viana, Ana Laura Tavares, Mirela Jobim de Azevedo
BACKGROUND: The best insulin regimen to treat hyperglycemia in hospitalized patients on nutritional support (NS) is unclear. METHODS: We searched electronic databases to identify cohort studies or randomized clinical trials in order to evaluate the efficacy of different insulin regimens used to treat hyperglycemia in hospitalized patients on NS on diverse outcomes: mean blood glucose (MBG), hypoglycemia, length of stay in hospital, and mortality. RESULTS: Seventeen studies from a total of 5,030 were included...
October 6, 2017: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/28992699/determination-of-benzyl-hexadecyldimethylammonium-1-4-bis-2-ethylhexyl-sulfosuccinate-vesicle-permeability-by-using-square-wave-voltammetry-and-an-enzymatic-reaction
#12
Airam K Cobo Solis, N Mariano Correa, Patricia G Molina
This report describes the studies performed to determine the permeability coefficient value (P) of 1-naphthyl phosphate (1-NP) through the benzyl-hexadecyldimethylammonium 1,4-bis(2-ethylhexyl)sulfosuccinate (AOT-BHD) vesicle bilayer. 1-NP was added in the external phase and must cross the bilayer of the vesicle to react with the encapsulated enzyme (alkaline phosphatase) to yield 1-naphtholate (NPh(-)), the product of the enzymatic hydrolysis. This product is electrochemically detected, at basic pH value, by a square wave voltammetry technique, which can be a good alternative over the spectroscopic one, to measure the vesicle solutions because scattering (due to its turbidity) does not make any influence in the electrochemical signal...
October 19, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28988013/aloe-vera-gel-improves-behavioral-deficits-and-oxidative-status-in-streptozotocin-induced-diabetic-rats
#13
Seyed Reza Fatemi Tabatabaei, Shahab Ghaderi, Mohammad Bahrami-Tapehebur, Yaghoob Farbood, Masome Rashno
Oxidative stress has a major role in progression of diabetes-related behavioral deficits. It has been suggested that Aloe vera has anti-diabetic, antioxidative, and neuroprotective effects. The present study was designed to determine the effects of Aloe vera gel on behavioral functions, oxidative status, and neuronal viability in the hippocampus of streptozotocin (STZ)-induced diabetic rats. Fifty five adult male Wistar rats were randomly divided into five groups, including: control (normal saline 8ml/kg/day; P...
October 10, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28982241/imidoylnitrenes-r-c-%C3%A2-nr-n-nitrile-imines-1h-diazirines-and-carbodiimides-interconversions-and-rearrangements-structures-and-energies-at-dft-and-caspt2-levels-of-theory
#14
Didier Bégué, Hugo Santos-Silva, Alain Dargelos, Curt Wentrup
The structures, energies, and rearrangements of imidoylnitrenes H-C(═NH)-N, H2N-C(═NH)-N, Ph-C(═NH)-N, H-C(═NPh)-N, and MeO-C(═NCN)-N (10a-e) are investigated at DFT and CASPT2 levels of theory. Imidoylnitrenes are potentially formed by pyrolysis or photolysis of azides, tetrazoles (6, 6'), or sydnones. Unlike most acylnitrenes, the imidoylnitrenes 10 have triplet ground states. The first excited states are the open-shell singlets (OSSs), lying between ca. 4 and 20 kcal mol(-1) above the triplets at the CASPT2 level...
October 19, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28960085/the-clinical-effectiveness-of-insulin-glargine-in-patients-with-type-i-diabetes-in-brazil-findings-and-implications
#15
Lays P Marra, Vânia E Araújo, Gerusa Cc Oliveira, Leonardo M Diniz, Augusto A Guerra Júnior, Francisco de Assis Acurcio, Brian Godman, Juliana Álvares
AIM: Published studies have challenged the cost-effectiveness of insulin glargine versus neutral protamine hagedorn (NPH) insulins in Brazil with limited evidence of increased effectiveness despite considerably higher acquisition costs. However, still a controversy. Consequently, there is a need to address this. MATERIALS & METHODS: Retrospective cohort study of Type I diabetes patients receiving insulin glargine in Brazil following NPH insulin who met the criteria...
September 29, 2017: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/28953430/long-term-use-of-long-acting-insulin-analogs-and-breast-cancer-incidence-in-women-with-type-2-diabetes
#16
Jennifer W Wu, Laurent Azoulay, Agnieszka Majdan, Jean-François Boivin, Michael Pollak, Samy Suissa
Purpose The association between long-acting insulin analogs and increased breast cancer risk is uncertain, particularly with the short follow-up in previous studies. We assessed this risk long term in women with type 2 diabetes. Methods A population-based cohort of women 40 years or older, all of whom were treated with long-acting (glargine, detemir) or neutral protamine Hagedorn (NPH) insulin between 2002 and 2012, was formed using the United Kingdom's Clinical Practice Research Datalink. Women were followed until February 2015 or breast cancer diagnosis...
November 10, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28951342/the-impact-of-ethnicity-educational-and-economic-status-on-the-prescription-of-insulin-therapeutic-regimens-and-on-glycemic-control-in-patients-with-type-1-diabetes-a-nationwide-study-in-brazil
#17
Marilia Brito Gomes, Melanie Rodacki, Elizabeth João Pavin, Roberta Arnoldi Cobas, João S Felicio, Lenita Zajdenverg, Carlos Antonio Negrato
AIMS: Establish the relationship between demographic, educational and economic status on insulin therapeutic regimens (ITRs) and on glycemic control in patients with type 1 diabetes. METHODS: This was a cross-sectional, multicenter study with 1760 patients conducted between August 2011 and August 2014 in 10 Brazilian cities. RESULTS: Patients were stratified according to ITRs as follows: only NPH insulin (group 1, n=80(4.5%)); only long-acting insulin analogs (group 2, n=6(0...
September 23, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28947761/human-cerebrospinal-fluid-promotes-long-term-neuronal-viability-and-network-function-in-human-neocortical-organotypic-brain-slice-cultures
#18
Niklas Schwarz, Ulrike B S Hedrich, Hannah Schwarz, Harshad P A, Nele Dammeier, Eva Auffenberg, Francesco Bedogni, Jürgen B Honegger, Holger Lerche, Thomas V Wuttke, Henner Koch
Pathophysiological investigation of CNS-related diseases, such as epilepsy or neurodegenerative disorders, largely relies on histological studies on human post mortem tissue, tissue obtained by biopsy or resective surgery and on studies using disease models including animal models, heterologous expression systems or cell culture based approaches. However, in general it remains elusive to what extent results obtained in model systems can be directly translated to the human brain, calling for strategies allowing validation or even primary investigation in live human CNS tissue...
September 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28943514/a-novel-kcnj11-mutation-associated-with-transient-neonatal-diabetes
#19
Evangelia Gole, Stavroula Oikonomou, Sian Ellard, Elisa De Franco, Kyriaki Karavanaki
BACKGROUND: Neonatal diabetes mellitus (NDM) is a rare type of monogenic diabetes that presents in the first 6 months of life. Activating mutations in the KCNJ11 gene encoding for the Kir6.2 subunit of the KATP channel can lead to transient (TNDM) or permanent neonatal diabetes mellitus (PNDM). CASE REPORT: A female infant presented at the 22nd day of life with severe hyperglycemia and ketoacidosis (glucose: 907mg/dl, blood gas pH: 6.84, HCO3: 6mmol/l). She was initially managed with intravenous (IV) fluids and IV insulin...
September 25, 2017: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/28892572/deconstructing-normal-pressure-hydrocephalus-ventriculomegaly-as-early-sign-of-neurodegeneration
#20
REVIEW
Alberto J Espay, Gustavo A Da Prat, Alok K Dwivedi, Federico Rodriguez-Porcel, Jennifer E Vaughan, Michela Rosso, Johnna L Devoto, Andrew P Duker, Mario Masellis, Charles D Smith, George T Mandybur, Aristide Merola, Anthony E Lang
Idiopathic normal pressure hydrocephalus (NPH) remains both oversuspected on clinical grounds and underconfirmed when based on immediate and sustained response to cerebrospinal fluid diversion. Poor long-term postshunt benefits and findings of neurodegenerative pathology in most patients with adequate follow-up suggest that hydrocephalic disorders appearing in late adulthood may often result from initially unapparent parenchymal abnormalities. We critically review the NPH literature, highlighting the near universal lack of blinding and controls, absence of specific clinical, imaging, or pathological features, and ongoing dependence for diagnostic confirmation on variable cutoffs of gait response to bedside fluid-drainage testing...
October 2017: Annals of Neurology
keyword
keyword
12495
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"