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https://www.readbyqxmd.com/read/28239949/temporal-trends-in-peripheral-arterial-interventions-observations-from-the-blue-cross-blue-shield-of-michigan-cardiovascular-consortium-bmc2-pvi
#1
Michael P Thomas, Yeo Jung Park, Scott Grey, Theodore L Schreiber, Hitinder S Gurm, Dale Leffler, Thomas P Davis, Peter Henke, Paul Michael Grossman
OBJECTIVES: The aim is to examine trends in procedural indication, arterial beds treated, and device usage in peripheral arterial interventions (PVIs). BACKGROUND: There is little data on indication, vascular beds treated and devices utilized for peripheral arterial interventions. METHODS: We used data from 43 hospitals participating in the BMC2 VIC registry. PVIs were separated by year and divided by arterial segment. Lower extremity PVIs were subclassified as having been performed for claudication or critical limb ischemia (CLI)...
February 27, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28239931/transition-readiness-adolescent-responsibility-and-executive-functioning-among-pediatric-transplant-recipients-caregivers-perspectives
#2
Ana M Gutierrez-Colina, Bonney Reed-Knight, Cyd Eaton, Jennifer Lee, Kristin Loiselle Rich, Laura Mee, Curtis Travers, Ronald L Blount
This study aimed both to evaluate caregivers' perspectives of EF and transition readiness among adolescent transplant recipients and to examine the indirect effects of adolescent responsibility and parent involvement across domains of EF. Fifty-seven caregivers of adolescent solid organ transplant recipients participated in this study and completed measures of adolescent EF, transition readiness, responsibility in healthcare behavior, and parent involvement. Bootstrapping procedures were used to test indirect effects...
February 27, 2017: Pediatric Transplantation
https://www.readbyqxmd.com/read/28239879/nonparametric-comparison-of-survival-functions-based-on-interval-censored-data-with-unequal-censoring
#3
Yanqin Feng, Ran Duan, Jianguo Sun
Nonparametric comparison of survival functions is one of the most commonly required task in failure time studies such as clinical trials, and for this, many procedures have been developed under various situations. This paper considers a situation that often occurs in practice but has not been discussed much: the comparison based on interval-censored data in the presence of unequal censoring. That is, one observes only interval-censored data, and the distributions of or the mechanisms behind censoring variables may depend on treatments and thus be different for the subjects in different treatment groups...
February 27, 2017: Statistics in Medicine
https://www.readbyqxmd.com/read/28239833/outcomes-of-laparoscopic-gastric-bypass-in-a-randomized-clinical-trial-compared-with-a-concurrent-national-database
#4
E Stenberg, E Szabo, J Ottosson, I Näslund
BACKGROUND: RCTs are the standard for assessing medical interventions, but they may not be feasible and their external validity is sometimes questioned. This study aimed to compare results from an RCT on mesenteric defect closure during laparoscopic gastric bypass with those from a national database containing data on the same procedure, to shed light on the external validity of the RCT. METHODS: Patients undergoing laparoscopic gastric bypass surgery within an RCT conducted between 1 May 2010 and 14 November 2011 were compared with those who underwent the same procedure in Sweden outside the RCT over the same time interval...
February 27, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28239830/implant-survival-and-success-rates-in-patients-with-risk-factors-results-from-a-long-term-retrospective-study-with-a-10-to-18-years-follow-up
#5
F De Angelis, P Papi, F Mencio, D Rosella, S Di Carlo, G Pompa
OBJECTIVE: Risk factors for implant therapy are represented by all general and local conditions that through various mechanisms can increase either short-term and long-term failure risk. The aim of this study is to assess the implant survival and implant success rates with single and multiple risk factors. PATIENTS AND METHODS: To address the research purpose, a retrospective cohort study was designed and implemented, including a sample of 225 patients with a total of 871 implants placed...
February 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28239778/-minimally-invasive-bypass-surgery-for-nasolacrimal-duct-obstruction-transcanalicular-laser-assisted-dacryocystorhinostomy
#6
K R Koch, C Cursiefen, L M Heindl
BACKGROUND: In recent years, the minimally invasive surgical procedure of transcanalicular laser-assisted dacryocystorhinostomy (TKL-DCR) has gained importance in the treatment of primary acquired nasolacrimal duct obstructions (PANDO). OBJECTIVES: Surgical indications, functional success rates, potential advantages, and complications of TKL-DCR are presented and compared with the standard procedures external (EXT-DCR) and endonasal DCR (EN-DCR). METHODS: The study comprises a PubMed literature review and our own clinical results...
February 26, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/28239777/-limbal-epithelial-stem-cell-transplantation-current-state-and-perspectives
#7
D Meller, H Thomasen
Homeostasis of the corneal surface is maintained by epithelial stem cells localized in the limbus. Multiple intrinsic factors or external injuries can destroy the delicate microenvironment of limbal epithelial stem cells causing a state which is termed limbal stem cell deficiency (LSCD). In such cases, re-epithelialization of the cornea is drastically impeded and conjunctival epithelium starts to extend beyond the limbus and to invade the corneal surface. In partial LSCD, a superficial keratectomy combined with an amniotic membrane is advised and helpful to restore an intact, healthy ocular surface...
February 26, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/28239771/can-training-change-attentional-breadth-failure-to-find-transfer-effects
#8
Lin Fang, Kristof Hoorelbeke, Lynn Bruyneel, Lies Notebaert, Colin MacLeod, Rudi De Raedt, Ernst H W Koster
Recently, there is increasing interest in the causal relationship between attentional breadth and emotion regulation. To test this causal relationship, attentional breadth needs to be manipulated stringently. The aim of the current research was to establish whether visual attentional breadth could be manipulated through experimental training procedures. We conducted two single-session training experiments and one multiple-session training experiment, all of which contained pre- and post-training assessments to test the direct transfer effects of training on attentional breadth construed in different measures...
February 26, 2017: Psychological Research
https://www.readbyqxmd.com/read/28239759/primary-acquired-spondylodiscitis-shows-a-more-severe-course-than-spondylodiscitis-following-spine-surgery-a-single-center-retrospective-study-of-159-cases
#9
Anja Tschugg, Sara Lener, Sebastian Hartmann, Andreas Rietzler, Sabrina Neururer, Claudius Thomé
Spondylodiscitis may arise primarily via hematogenous spread or direct inoculation of virulent organisms during spine surgery. To date, no comparative data investigating the differences between primary and postoperative spondylodiscitis is available. Thus, the purpose of this retrospective study was to investigate differences between these two etiologies. One hundred fifty-nine patients that were treated at our department were included in the retrospective analysis. The patients were categorized into two groups based on the etiology of spondylodiscitis: group NS, primary spondylodiscitis without prior spinal surgery; group S, spondylodiscitis following spinal surgery...
February 27, 2017: Neurosurgical Review
https://www.readbyqxmd.com/read/28239752/potential-and-limitations-of-cochrane-reviews-in-pediatric-cardiology-a-systematic-analysis
#10
Martin Poryo, Sara Khosrawikatoli, Hashim Abdul-Khaliq, Sascha Meyer
Evidence-based medicine has contributed substantially to the quality of medical care in pediatric and adult cardiology. However, our impression from the bedside is that a substantial number of Cochrane reviews generate inconclusive data that are of limited clinical benefit. We performed a systematic synopsis of Cochrane reviews published between 2001 and 2015 in the field of pediatric cardiology. Main outcome parameters were the number and percentage of conclusive, partly conclusive, and inconclusive reviews as well as their recommendations and their development over three a priori defined intervals...
February 27, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28239750/light-and-laser-treatment-modalities-for-disseminated-superficial-actinic-porokeratosis-a-systematic-review
#11
Gregory A Aird, Jenna L Sitenga, Austin Huy Nguyen, Adam Vaudreuil, Christopher J Huerter
Treatment of disseminated superficial actinic porokeratosis (DSAP) is poorly standardized. The present review seeks to comprehensively discuss the potential for laser and light modalities in the treatment of DSAP. A systematic review of light and laser treatment modalities was conducted to include 26 cases of patients with DSAP. Systematic review resulted in 14 articles to be included. Photodynamic therapy (PDT) overall was the least successful treatment modality, with clinical improvement seen in a minority of patients (MAL-PDT: N = 9 patients, 33...
February 27, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28239727/twist-it-the-acid-dependent-isomerization-of-homoleptic-carbenic-iridium-iii-complexes
#12
Jaroslaw G Osiak, Tobias Setzer, Peter G Jones, Christian Lennartz, Andreas Dreuw, Wolfgang Kowalsky, Hans-Hermann Johannes
The first successful meridional to facial isomerization of homoleptic carbenic iridium(iii) complexes is presented. The Brønsted-acid-mediated procedure allows the conversion of large amounts of material and additionally provides an in situ purification because of precipitation of the target material during the reaction. The pronounced acid-dependency of the reaction yield observed for tris(N-phenyl,N-methyl-benzimidazol-2-yl)iridium(iii) and tris(N-phenyl,N-benzyl-benzimidazol-2-yl)iridium(iii) was investigated by labelling experiments and quantum chemical calculations...
February 27, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28239588/a-decade-of-experience-of-management-of-thyroglossal-duct-cyst-in-a-tertiary-care-hospital-differentiation-between-children-and-adults
#13
Shakeel Uz Zaman, Mubasher Ikram, Mohammad Sohail Awan, Nabeel Humayun Hassan
Variations in thyroglossal duct cysts (TGDCs) between children and adult are mentioned very little in literature. The lesion mostly found in children but adult population also possesses this anomaly. The aim of this study was to determine the differences in clinical presentations and surgical outcomes of TGDC between children and adults. A retrospective chart review of all patients with TGDCs managed in our hospital from July 2004 to June 2014. All records were reviewed for age, sex, location of cyst in neck and with relation to hyoid bone, size, postoperative complication and recurrence rates...
March 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/28239580/facial-nerve-paralysis-in-acute-suppurative-otitis-media-management
#14
Sriranga Prasad, K V Vishwas, Swetha Pedaprolu, R Kavyashree
Facial paralysis is a rare complication of acute suppurative otitis media which requires early detection and appropriate care. We hereby report a case which we managed conservatively with good outcome. Following our experience and review of literature on the subject, antibiotic therapy and corticosteroid therapy, with or without myringotomy were found to be the first-line procedures. Surgery should be employed in case of acute or coalescent mastoiditis, suppurative complications and lack of clinical regression...
March 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/28239578/nasopharyngeal-angiofibroma-paradigm-shift-in-management
#15
Manzoor Ahmad Latoo, Waqar Ul Hamid, Aleena Shafi Jallu, Mudasir Ul Islam, Rafiq Ahmad Pampori
To report on a series of patients of nasopharyngeal angiofibroma of varied ages with different stages and management algorithm which reduced morbidity associated with this tumour. Retrospective. We report a series of ten patients who presented to a tertiary care institution and were diagnosed to have NA from 2012 to 2014. Patients were categorized by Radkowski staging and data was collected to document differences in terms of presentation, operative technique, and postoperative course. All patients underwent preoperative embolization...
March 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/28239574/do-nasal-surgeries-affect-mucociliary-clearance
#16
Rajeshwary Aroor, Zainab Sunu Ali, K S Gangadhara Somayaji
The study was conducted to assess the impact of different nasal surgeries on the nasal mucociliary clearance mechanism. Mucociliary function of the nasal mucosa of patients who were undergoing various nasal surgeries was assessed by the Saccharin test by placing 5 mg saccharin granule on the anterior end of the inferior turbinate 1 day prior to the surgery. The time required for the test subject to experience a sweet taste was measured in minutes. Post-operatively the test was repeated 6 weeks after the surgery and the test times were compared...
March 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/28239509/system-design-and-development-of-a-robotic-device-for-automated-venipuncture-and-diagnostic-blood-cell-analysis
#17
Max L Balter, Alvin I Chen, Alex Fromholtz, Alex Gorshkov, Tim J Maguire, Martin L Yarmush
Diagnostic blood testing is the most prevalent medical procedure performed in the world and forms the cornerstone of modern health care delivery. Yet blood tests are still predominantly carried out in centralized labs using large-volume samples acquired by manual venipuncture, and no end-to-end solution from blood draw to sample analysis exists today. Our group is developing a platform device that merges robotic phlebotomy with automated diagnostics to rapidly deliver patient information at the site of the blood draw...
October 2016: Proceedings of the ... IEEE/RSJ International Conference on Intelligent Robots and Systems
https://www.readbyqxmd.com/read/28239482/aggressive-clinical-approach-to-obesity-improves-metabolic-and-clinical-outcomes-and-can-prevent-bariatric-surgery-a-single-center-experience
#18
Flavio A Cadegiani, Gustavo C Diniz, Gabriella Alves
BACKGROUND: The number of bariatric procedures has exponentially increased in the past decade, as a result of the lack of successful clinical weight-loss interventions. The main reasons for the failure of clinical obesity management are: (1) anti-obesity medications are administered as monotherapies (or pre-combined drugs); (2) lack of combination between pharmacotherapy and non-pharmacological modalities; (3) short duration of pharmacotherapy for obesity; (4) lack of weight-loss maintenance strategies; (5) misunderstanding of the complex pathophysiology of obesity; and (6) underprescription of anti-obesity medications...
2017: BMC Obesity
https://www.readbyqxmd.com/read/28239457/covariate-selection-for-multilevel-models-with-missing-data
#19
Miguel Marino, Orfeu M Buxton, Yi Li
Missing covariate data hampers variable selection in multilevel regression settings. Current variable selection techniques for multiply-imputed data commonly address missingness in the predictors through list-wise deletion and stepwise-selection methods which are problematic. Moreover, most variable selection methods are developed for independent linear regression models and do not accommodate multilevel mixed effects regression models with incomplete covariate data. We develop a novel methodology that is able to perform covariate selection across multiply-imputed data for multilevel random effects models when missing data is present...
2017: Stat: the ISI's Journal for Rapid Dissemination of Statistics Research
https://www.readbyqxmd.com/read/28239456/chronic-anal-fissures-open-lateral-internal-sphincterotomy-result-a-case-series-study
#20
Abdulwahid M Salih
INTRODUCTION: Anal fissure are defined as a tear in the skin of the anal canal distal to dentate line. Although still there are controversies about the exact management, lateral sphincterotomy is promising. The aim of this series is to present the outcome of lateral sphincterotomy for internal anal sphincter in term of patient satisfaction and complication. PATIENT AND METHODS: A prospective single cohort study, 190 patients, who were undergone lateral sphincterotomy for internal anal sphincter from 2010 to 2014, were analyzed...
March 2017: Annals of Medicine and Surgery
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