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https://www.readbyqxmd.com/read/29035792/evolution-of-consciousness-of-exposure-to-siloxanes-review-of-publications
#1
REVIEW
Krystyna Mojsiewicz-Pieńkowska, Dominika Krenczkowska
The purpose of this description is to review scientific literature from 1944 to 2017 as a source of information on the reasons for the increased interest in siloxanes (silicones). Not only the research area, but first, the changes in the tendency of research aims are important issues in the evaluation. On the one hand, the authors emphasize the unique properties of linear and cyclic siloxanes, providing many examples of beneficial applications, and on the other hand, there are some warnings of overcoming of the safety barrier of their presence in human environment...
October 9, 2017: Chemosphere
https://www.readbyqxmd.com/read/29035495/medical-devices-gastroenterology-urology-devices-classification-of-the-enzyme-packed-cartridge-final-order
#2
(no author information available yet)
The Food and Drug Administration (FDA or we) is classifying the enzyme packed cartridge into class II (special controls). The special controls that apply to the device type are identified in this order and will be part of the codified language for the enzyme packed cartridge's classification. We are taking this action because we have determined that classifying the device into class II (special controls) will provide a reasonable assurance of safety and effectiveness of the device. We believe this action will also enhance patients' access to beneficial innovative devices, in part by reducing regulatory burdens...
October 16, 2017: Federal Register
https://www.readbyqxmd.com/read/29035494/medical-devices-immunology-and-microbiology-devices-classification-of-the-automated-image-assessment-system-for-microbial-colonies-on-solid-culture-media-final-order
#3
(no author information available yet)
The Food and Drug Administration (FDA or we) is classifying the automated image assessment system for microbial colonies on solid culture media into class II (special controls). The special controls that apply to the device type are identified in this order and will be part of the codified language for the automated image assessment system for microbial colonies on solid culture media's classification. We are taking this action because we have determined that classifying the device into class II (special controls) will provide a reasonable assurance of safety and effectiveness of the device...
October 16, 2017: Federal Register
https://www.readbyqxmd.com/read/29035493/medical-devices-immunology-and-microbiology-devices-classification-of-the-nucleic-acid-based-device-for-the-amplification-detection-and-identification-of-microbial-pathogens-directly-from-whole-blood-specimens-final-order
#4
(no author information available yet)
The Food and Drug Administration (FDA or we) is classifying the nucleic acid-based device for the amplification, detection, and identification of microbial pathogens directly from whole blood specimens into class II (special controls). The special controls that apply to the device type are identified in this order and will be part of the codified language for the nucleic acid-based device for the amplification, detection, and identification of microbial pathogens directly from whole blood specimens' classification...
October 16, 2017: Federal Register
https://www.readbyqxmd.com/read/29034010/developing-a-framework-of-gastronomic-systems-research-to-unravel-drivers-of-food-choice
#5
Rosa Paula Cuevas, Annalyn de Guia, Matty Demont
Nutritional and dietary interventions and the introduction of novel food products and ingredients require a thorough understanding of the drivers of food choice, which are embedded in local context and culture. We developed a framework of "gastronomic systems research" (GSR) to understand culture-specific consumer food choice, and contextualise it to a target population of urban, middle- to high-income Filipino consumers to assess the domestic niche market potential of traditional rice varieties in the Philippines...
October 2017: Int J Gastron Food Sci
https://www.readbyqxmd.com/read/29033032/ring-vaccination-with-rvsv-zebov-under-expanded-access-in-response-to-an-outbreak-of-ebola-virus-disease-in-guinea-2016-an-operational-and-vaccine-safety-report
#6
Pierre-Stéphane Gsell, Anton Camacho, Adam J Kucharski, Conall H Watson, Aminata Bagayoko, Severine Danmadji, Natalie E Dean, Abdourahamane Diallo, Abdourahmane Diallo, Honora Djidonou, Moussa Doumbia, Godwin Enwere, Elizabeth S Higgs, Thomas Mauget, Diakite Mory, Ximena Riveros, Fofana Thierno Oumar, Alhassane Toure, Andrea S Vicari, Ira M Longini, W J Edmunds, Ana Maria Henao-Restrepo, Marie Paule Kieny, Sakoba Kéïta
BACKGROUND: In March, 2016, a flare-up of Ebola virus disease was reported in Guinea, and in response ring vaccination with the unlicensed rVSV-ZEBOV vaccine was introduced under expanded access, the first time that an Ebola vaccine has been used in an outbreak setting outside a clinical trial. Here we describe the safety of rVSV-ZEBOV candidate vaccine and operational feasibility of ring vaccination as a reactive strategy in a resource-limited rural setting. METHODS: Approval for expanded access and compassionate use was rapidly sought and obtained from relevant authorities...
October 9, 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/29032632/linking-agriculture-and-nutrition-education-to-improve-infant-and-young-child-feeding-lessons-for-future-programmes
#7
Ellen Muehlhoff, Ramani Wijesinha-Bettoni, Elizabeth Westaway, Theresa Jeremias, Stacia Nordin, Julia Garz
Agriculture and food systems play a central role in nutrition by supplying nutritious, healthy and affordable foods. When integrated with nutrition education for behaviour change, agricultural interventions that supply diverse affordable foods from all food groups have great scope for improving young child and family diets. In 2014, process reviews were conducted in Cambodia and Malawi of food security projects that provided agricultural support and community-based nutrition education on improved infant and young child feeding (IYCF)...
October 2017: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/29032631/tools-to-improve-planning-implementation-monitoring-and-evaluation-of-complementary-feeding-programmes
#8
Juliawati Untoro, Rachel Childs, Indira Bose, Pattanee Winichagoon, Christiane Rudert, Andrew Hall, Saskia de Pee
Adequate nutrient intake is a prerequisite for achieving good nutrition status. Suboptimal complementary feeding practices are a main risk factor for stunting. The need for systematic and user-friendly tools to guide the planning, implementation, monitoring, and evaluation of dietary interventions for children aged 6-23 months has been recognized. This paper describes five tools, namely, ProPAN, Optifood, Cost of the Diet, Fill the Nutrient Gap, and Monitoring Results for Equity System that can be used in different combinations to improve situation analysis, planning, implementation, monitoring, or evaluation approaches for complementary feeding in a particular context...
October 2017: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/29032630/risk-factors-of-poor-complementary-feeding-practices-in-pakistani-children-aged-6-23%C3%A2-months-a-multilevel-analysis-of-the-demographic-and-health-survey-2012-2013
#9
Muzi Na, Víctor M Aguayo, Mary Arimond, Christine P Stewart
Appropriate feeding practices are crucial for survival, growth, and development in childhood. This paper analyzes Pakistan's Demographic and Health Survey 2012-2013 to fill the knowledge gap in risk factors of poor complementary feeding practices in Pakistani children. Multilevel models were applied to fit the multistage cluster sample of 2,827 children aged 6-23 months from 489 communities. Introduction of solid, semi-solid, or soft foods (intro) was achieved in 67% infants aged 6-8 months. Among children aged 6-23 months, the proportion of children meeting minimum meal frequency, dietary diversity (MDD), and acceptable diet criteria were 63%, 22% and 15%, respectively...
October 2017: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/29032626/using-behavior-change-approaches-to-improve-complementary-feeding-practices
#10
Tina Sanghvi, Renata Seidel, Jean Baker, Ann Jimerson
This paper applies an implementation framework, based on a behavior change model, to compare four case studies of complementary feeding programs. It aims to expand our understanding of how to design and implement behavior change interventions aimed at improving complementary feeding practices. Four programs met the selection criteria of scale and documented improvements: Bangladesh, Malawi, Peru, and Zambia. We examined commonalities and differences in the design and implementation of social and behavior change approaches, use of program delivery platforms, challenges encountered, and lessons learned...
October 2017: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/29032623/complementary-feeding-practices-current-global-and-regional-estimates
#11
Jessica M White, France Bégin, Richard Kumapley, Colleen Murray, Julia Krasevec
Insufficient quantities and inadequate quality of complementary foods, together with poor feeding practices, pose a threat to children's health and nutrition. Interventions to improve complementary feeding are critical to reduce all forms of malnutrition, and access to data to ascertain the status of complementary feeding practices is essential for efforts to improve feeding behaviours. However, sufficient data to generate estimates for the core indicators covering the complementary feeding period only became available recently...
October 2017: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/29032622/harnessing-private-sector-expertise-to-improve-complementary-feeding-within-a-regulatory-framework-where-is-the-evidence
#12
Marti J van Liere, Dessie Tarlton, Ravi Menon, M Yellamanda, Ietje Reerink
Global recognition that the complex and multicausal problems of malnutrition require all players to collaborate and to invest towards the same objective has led to increased private sector engagement as exemplified through the Scaling Up Nutrition Business Network and mechanisms for blended financing and matched funding, such as the Global Nutrition for Growth Compact. The careful steps made over the past 5 to 10 years have however not taken away or reduced the hesitation and scepticism of the public sector actors towards commercial or even social businesses...
October 2017: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/29032619/first-foods-why-improving-young-children-s-diets-matter
#13
France Bégin, Víctor M Aguayo
Globally, only 52% of children aged 6-23 months meet the minimum meal frequency and a mere 29% meet the minimum dietary diversity, with large disparities across and within regions. With most of the stunting occurring during the first thousand days-from conception to age 2 years-improving complementary feeding in children 6-23 months old is an urgent priority. With this evidence in mind, UNICEF collaborated with the governments of India and Maharashtra to convene a global meeting in Mumbai, India, under the theme: First Foods: A Global Meeting to Accelerate Progress on Complementary Feeding in Young Children (November 17-18, 2015)...
October 2017: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/29032464/nutritional-composition-of-honey-bee-food-stores-vary-with-floral-composition
#14
Philip Donkersley, Glenn Rhodes, Roger W Pickup, Kevin C Jones, Eileen F Power, Geraldine A Wright, Kenneth Wilson
Sufficiently diverse and abundant resources are essential for generalist consumers, and form an important part of a suite of conservation strategies for pollinators. Honey bees are generalist foragers and are dependent on diverse forage to adequately meet their nutritional needs. Through analysis of stored pollen (bee bread) samples obtained from 26 honey bee (Apis mellifera L.) hives across NW-England, we quantified bee bread nutritional content and the plant species that produced these stores from pollen...
October 14, 2017: Oecologia
https://www.readbyqxmd.com/read/29031108/accessibility-of-fast-food-outlets-is-associated-with-fast-food-intake-a-study-in-the-capital-region-of-denmark
#15
Kamille Almer Bernsdorf, Cathrine Juel Lau, Anne Helms Andreasen, Ulla Toft, Maja Lykke, Charlotte Glümer
Literature suggests that people living in areas with a wealth of unhealthy fast food options may show higher levels of fast food intake. Multilevel logistic regression analyses were applied to examine the association between GIS-located fast food outlets (FFOs) and self-reported fast food intake among adults (+ 16 years) in the Capital Region of Denmark (N = 48,305). Accessibility of FFOs was measured both as proximity (distance to nearest FFO) and density (number of FFOs within a 1km network buffer around home)...
October 11, 2017: Health & Place
https://www.readbyqxmd.com/read/29029291/nutrition-influences-caffeine-mediated-sleep-loss-in-drosophila
#16
Erin S Keebaugh, Jin Hong Park, Chenchen Su, Ryuichi Yamada, William W Ja
Study objectives: Plant-derived caffeine is regarded as a defensive compound produced to prevent herbivory. Caffeine is generally repellent to insects and often used to study the neurological basis for aversive responses in the model insect, Drosophila melanogaster. Caffeine is also studied for its stimulatory properties where sleep or drowsiness is suppressed across a range of species. Since limiting access to food also inhibits fly sleep-an effect known as starvation-induced sleep suppression-we tested whether aversion to caffeinated food results in reduced nutrient intake and assessed how this might influence fly studies on the stimulatory effects of caffeine...
October 3, 2017: Sleep
https://www.readbyqxmd.com/read/29029268/development-and-validation-of-a-method-for-the-detection-of-%C3%AE-and-%C3%AE-endosulfan-organochlorine-insecticide-in-calliphora-vomitoria-diptera-calliphoridae
#17
Paola A Magni, Marco Pazzi, Marco Vincenti, Valerio Converso, Ian R Dadour
Entomotoxicology studies employ analytical methods and instrumentation to detect chemical substances in carrion insects feeding from the decomposing tissues. The identification of such chemicals may determine the cause of death and may be used for the estimation of the minimum time since death. To date, the main focus of entomotoxicological studies has been the detection of drugs, whereas little information concerns the effects of pesticides on blowflies. Pesticides are generally freely available and more affordable than drugs but they can also be a home hazard and an accessible candidate poison at a crime scene...
October 4, 2017: Journal of Medical Entomology
https://www.readbyqxmd.com/read/29028788/efficacy-and-safety-of-pembrolizumab-in-patients-enrolled-in-keynote-030-in-the-united-states-an-expanded-access-program
#18
Tara C Gangadhar, Wen-Jen Hwu, Michael A Postow, Omid Hamid, Adil Daud, Roxana Dronca, Richard Joseph, Steven J O'Day, F S Hodi, Anna C Pavlick, Harriet Kluger, Romina P Oxborough, Aiming Yang, Mihaela Gazdoiu, Debra A Kush, Scot Ebbinghaus, April K S Salama
KEYNOTE-030 (ClinicalTrials.gov ID, NCT02083484) was a global expanded access program that allowed access to pembrolizumab, an antiprogrammed death 1 antibody, for patients with advanced melanoma before its regulatory approval. Patients with unresectable stage III/IV melanoma that progressed after standard-of-care therapy, including ipilimumab and, if BRAF mutant, a BRAF inhibitor, were eligible to receive pembrolizumab 2 mg/kg every 3 weeks. Response was assessed by immune-related response criteria by investigator review...
November 2017: Journal of Immunotherapy
https://www.readbyqxmd.com/read/29025505/household-food-security-discordance-among-latino-adolescents-and-parents
#19
Fiorella L Carlos Chavez, Daphne C Hernandez, Gregory J Harris, Joseph G Grzywacz
OBJECTIVES: We determined the degree of parent-adolescent concordance in reported household food security, and delineated variation in concordance as a function of selected household and parent-adolescent relationship characteristics. METHODS: Cross-tabulations and Cohen's Kappa determined concordance. Multinomial logistic regressions delineated variation in concordance as a function of selected household and parent-adolescent relationship characteristics for Latino parent and adolescent dyads (N = 70)...
November 1, 2017: American Journal of Health Behavior
https://www.readbyqxmd.com/read/29024264/deutetrabenazine-for-tardive-dyskinesia-a-systematic-review-of-the-efficacy-and-safety-profile-for-this-newly-approved-novel-medication-what-is-the-number-needed-to-treat-number-needed-to-harm-and-likelihood-to-be-helped-or-harmed
#20
REVIEW
Leslie Citrome
OBJECTIVE: Deutetrabenazine is a deuterated formulation of tetrabenazine. The aim of this systematic review is to describe the efficacy, tolerability and safety of deutetrabenazine for the treatment of tardive dyskinesia (TD). DATA SOURCES: The pivotal registration trials were accessed by querying http://www.ncbi.nlm.nih.gov/pubmed/ and http://www.clinicaltrials.gov, for the search terms 'deutetrabenazine' OR 'SD-809', and by also querying the EMBASE (Elsevier) commercial database for clinical poster abstracts, and by asking the manufacturer for copies of posters presented at congresses...
October 12, 2017: International Journal of Clinical Practice
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