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PD, Peritoneal Dialysis

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https://www.readbyqxmd.com/read/29163160/aberrant-wnt-beta-catenin-pathway-activation-in-dialysate-induced-peritoneal-fibrosis
#1
Yuanyuan Guo, Lin Sun, Li Xiao, Rong Gou, Yudong Fang, Yan Liang, Ruiqiang Wang, Ningjun Li, Fuyou Liu, Lin Tang
Peritoneal dialysis (PD)-associated peritoneal fibrosis is a chronic progress which induces ultrafiltration failure. It remains a challenge to prevent the progression of PD-associated fibrosis in clinic practice. Wnt/β-catenin pathway plays important role in many severe fibrotic diseases, here we investigated its contribution to the development of peritoneal damage. We isolated mesothelial cells (MC) from the effluent of PD patients and found that the expressions of Wnt1, Wnt5a, β-catenin, and LEF1 were increased in patients with more than 1-year PD compared with patients who just started with PD (<1 month)...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29162681/clusters-of-practice-in-peritoneal-dialysis-in-france-data-from-the-catheter-section-of-the-rdplf
#2
Antoine Lanot, Clemence Bechade, Christian Verger, Emmanuel Fabre, Isabelle Vernier, Thierry Lobbedez
BACKGROUND: Peritonitis is a major cause of peritoneal dialysis (PD) failure. Recommendations for the prevention of peritonitis are available, but wide variations exist in the peritonitis rate among countries and PD units. The objective of this study was to describe the different pattern of practices in France. METHODS: This was a retrospective, multicenter study based on data from the French Language Peritoneal Dialysis Registry. Center practices were described and mapped...
November 21, 2017: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/29162680/peritoneal-dialysis-in-orthotopic-liver-transplantation-recipients
#3
Nalinee Saiprasertkit, Camila Nihei, Joanne M Bargman
BACKGROUND: In many dialysis programs, there is resistance to initiating peritoneal dialysis (PD) in liver transplant patients needing renal replacement therapy. This retrospective study reviews the outcome of PD in liver transplant patients at a major transplantation and dialysis center. METHOD: We performed a retrospective cohort study in patients who underwent liver transplants and received PD between 1991 and 2016. Patient demographics, laboratory parameters, and adverse events were collected from our electronic database...
November 21, 2017: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/29162679/safety-of-peritoneal-dialysis-after-nonrenal-solid-organ-transplantation
#4
Anne Buffet, Sonia Guillouët, Thierry Lobbedez, Maxence Ficheux, Antoine Lanot, Clemence Bechade
BACKGROUND: End-stage renal disease is a well-known complication after solid-organ transplantation, mostly as a result of calcineurin-inhibitor therapy. Among recipients of solid-organ transplants other than kidneys, peritoneal dialysis (PD) has been considered an accessory technique as an increased risk of infectious complications has been reported. The aim of our study was to evaluate the outcome of patients with a liver, heart, or lung transplant who underwent PD for replacement therapy...
November 21, 2017: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/29162678/stability-of-ceftazidime-and-heparin-in-four-different-types-of-peritoneal-dialysis-solutions
#5
Surendra Kandel, Syed Tabish R Zaidi, Troy Wanandy, Long Ming, Ronald Castelino, Kamal Sud, Rahul P Patel
BACKGROUND: Intraperitoneal (IP) administration of ceftazidime is recommended for the treatment of peritoneal dialysis-associated peritonitis (PDAP) from Pseudomonas. Patients with PDAP may also need IP heparin to overcome problems with drainage of turbid peritoneal dialysis (PD) fluids and blockage of catheters with fibrin. Physico-chemical stability of ceftazidime and heparin, and biological stability of heparin in many types of PD solutions is unknown. Therefore, we investigated the stability of ceftazidime and heparin in 4 types of PD solutions...
November 21, 2017: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/29162677/feasibility-of-urgent-start-peritoneal-dialysis-in-older-patients-with-end-stage-renal-disease-a-single-center-experience
#6
Haijiao Jin, Zhaohui Ni, Shan Mou, Renhua Lu, Wei Fang, Jiaying Huang, Chunhua Hu, Haifen Zhang, Hao Yan, Zhenyuan Li, Zanzhe Yu
BACKGROUND: Patients with end-stage renal disease (ESRD) frequently require urgent-start dialysis. Recent evidence suggests that peritoneal dialysis (PD) might be a feasible alternative to hemodialysis (HD) in these patients, including in older patients. METHODS: This retrospective study enrolled patients aged > 65 years with ESRD who underwent urgent dialysis without functional vascular access or PD catheter at a single center, from January 2011 to December 2014...
November 21, 2017: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/29161695/a-randomized-controlled-trial-of-comparing-ultrasound-guided-transversus-abdominis-plane-block-with-local-anesthetic-infiltration-in-peritoneal-dialysis-catheter-implantation
#7
Qi Li, Xiaohong Tang, Tian Tao, Wenjuan Zhang, Wei Qin, Jie Zhang, Zi Li
BACKGROUND: The ultrasound-guided transversus abdominis plane (TAP) block has been demonstrated as a useful analgesia technique in lower-abdomen surgeries. We hypothesized that it could be the principal anesthesia technique for end-stage renal disease (ESRD) patients undergoing peritoneal dialysis (PD) catheter (PDC) implantation using the open dissection method. METHODS: This was a single-center, prospective, randomized, and double-blinded study. All eligible patients were randomized into 2 groups: the TAP block group (n = 20) and the local anesthetic infiltration (LAI) group (n = 20)...
November 22, 2017: Blood Purification
https://www.readbyqxmd.com/read/29161688/plasma-beta-trace-protein-as-a-marker-of-residual-renal-function-the-effect-of-different-hemodialysis-modalities-and-intra-individual-variability-over-time
#8
Amaryllis H van Craenenbroeck, Ann-Christin Bragfors-Helin, Abdul Rashid Qureshi, Bengt Lindholm, Bodil Sjöberg, Björn Anderstam, Olof Heimburger, Peter Stenvinkel, Peter Bárány
BACKGROUND/AIMS: Beta-trace protein (BTP) is a low-molecular-weight molecule, which may be used to assess residual renal function (RRF) in dialysis patients. Here we evaluated the influence of hemodialysis (HD) and hemodiafiltration (HDF) on plasma BTP, and analyzed the inter- and intra-individual variability of plasma BTP over time in HD and peritoneal dialysis (PD) patients. METHODS: In 12 prevalent HD patients, the effect of a single session of low-flux HD, high-flux HD and HDF on plasma BTP was studied...
November 22, 2017: Kidney & Blood Pressure Research
https://www.readbyqxmd.com/read/29161686/impact-of-an-in-hospital-patient-education-program-on-choice-of-renal-replacement-modality-in-unplanned-dialysis-initiation
#9
Moritz Schanz, Markus Ketteler, Markus Heck, Juergen Dippon, Mark Dominik Alscher, Martin Kimmel
BACKGROUND/AIMS: Up to 50% patients requiring dialysis receive an urgent, unplanned start (UPS) to renal replacement therapy (RRT). Most of these are initiated with an intravenous catheter and commenced and maintained on hemodialysis (HD). Although peritoneal dialysis (PD) could be an equipotent initial modality for RRT, it is used less frequently as long-term RRT in UPS patients. This multicenter-study aimed to evaluate the impact of a structured, in-hospital education program and factors influencing PD rates, especially in UPS patients...
November 21, 2017: Kidney & Blood Pressure Research
https://www.readbyqxmd.com/read/29160975/peritoneal-dialysis-access-management-more-than-skin-deep
#10
Susan Bridger
Providing care and education for a patient on peritoneal dialysis (PD) requires that the nephrology nurse have knowledge and expertise in the PD access. This article provides information on types and placement of PD catheters, pre-placement and post-placement education and care, how to assess PD catheter exit site healing, and initial use of the PD catheter for access.
September 2017: Nephrology Nursing Journal: Journal of the American Nephrology Nurses' Association
https://www.readbyqxmd.com/read/29158495/the-prevalence-of-muscle-wasting-sarcopenia-in-peritoneal-dialysis-patients-varies-with-ethnicity-due-to-differences-in-muscle-mass-measured-by-bioimpedance
#11
Suree Yoowannakul, Kamonwan Tangvoraphonkchai, Andrew Davenport
BACKGROUND/OBJECTIVES: Sarcopenia is associated with increased mortality. European and North American recommended screening for low muscle mass uses gender specific cut points, with no adjustment for ethnicity. We wished to determine whether the prevalence of sarcopenia was altered by ethnicity in peritoneal dialysis (PD) patients. SUBJECTS/METHODS: We measured appendicular lean mass indexed to height (ALMI) in PD patients by segmental bioimpedance and determined sarcopenia using different cut off points for reduced muscle mass...
November 21, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29151492/determinants-of-the-change-in-arterial-stiffness-in-peritoneal-dialysis-patients
#12
Mitsutaka Nakahigashi, Hiroyasu Tsukaguchi, Satoshi Morimoto, Chikara Nakano, Hiroko Ueda, Kazunori Someya, Makiko Kusabe, Sanae Kikuchi, Takanobu Imada, Ichiro Shiojima
Arterial stiffness is an important risk factor for cardiovascular disease (CVD) in patients with end-stage renal failure. However, little is known about the factors that contribute to arterial rigidity in peritoneal dialysis (PD) patients. The aim of this study was to define the pattern and determinants of the longitudinal change in arterial stiffness after PD initiation.Arterial stiffening was estimated for 46 PD patients by using brachial-ankle pulse wave velocity (baPWV) and carotid intima-media thickness (cIMT)...
November 17, 2017: International Heart Journal
https://www.readbyqxmd.com/read/29151280/oral-nutritional-supplementation-in-patients-undergoing-peritoneal-dialysis-a-randomised-crossover-pilot-study
#13
Karen M Salamon, Kelly Lambert
BACKGROUND: Malnutrition is a significant problem in those undergoing peritoneal dialysis (PD). Factors such as gastrointestinal (GI) symptoms and the need for a fluid reduced diet can limit tolerance and thereby the efficacy of oral nutritional supplements to treat malnutrition. OBJECTIVES: To evaluate the acceptability and impact of two different forms of oral nutrition supplementation for 16 weeks on nutritional markers and quality of life of malnourished patients undergoing PD...
November 19, 2017: Journal of Renal Care
https://www.readbyqxmd.com/read/29150711/epidemiology-of-peritonitis-following-maintenance-peritoneal-dialysis-catheter-placement-during-infancy-a-report-of-the-scope-collaborative
#14
Joshua Jacob Zaritsky, Coral Hanevold, Raymond Quigley, Troy Richardson, Cynthia Wong, Jennifer Ehrlich, John Lawlor, Jonathan Rodean, Alicia Neu, Bradley A Warady
BACKGROUND: Maintenance peritoneal dialysis (PD) is the dialysis modality of choice for infants and young children. However, there are limited outcome data for those who undergo PD catheter insertion and initiate maintenance PD within the first year of life. METHODS: Using data from the Children's Hospital Association's Standardizing Care to Improve Outcomes in Pediatric End Stage Renal Disease (ESRD) Collaborative (SCOPE), we examined peritonitis rates and patient survival in 156 infants from 29 North American pediatric dialysis centers who had a chronic PD catheter placed prior to their first birthday...
November 17, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/29149949/attitudes-toward-organ-donation-among-relatives-of-the-patients-who-are-being-followed-up-in-intensive-care-and-dialysis-units
#15
B Kahveci, K Topal, Ç Gereklioglu, H Aksoy
INTRODUCTION: This study sought to investigate attitudes toward organ donation (OD) among the relatives of patients who are being followed up in intensive care units (ICU) and dialysis units. MATERIALS AND METHODS: This cross-sectional study was conducted with relatives of the patients who were being followed up in hemodialysis (HD) and peritoneal dialysis (PD) units and Neurosurgery, Neurology, Anesthesia, and Reanimation ICUs of Adana Numune Research and Training Hospital...
November 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/29148022/hemodialysis-versus-peritoneal-dialysis-an-observational-study-in-two-international-centers
#16
Renhua Lu, Carla Estremadoyro, Xiaohuan Chen, Mingli Zhu, Leonardo C Ribeiro, Yucheng Yan, Alessandra Brendolan, Wei Fang, Carlo Crepaldi, Zhaohui Ni, Leyi Gu, Claudio Ronco
INTRODUCTION: Given that it is difficult to randomize end-stage renal disease (ESRD) patients to either hemodialysis (HD) or peritoneal dialysis (PD), differences between these renal replacement therapy (RRT) modalities are of major interest and remain controversial. METHODS: All data on maintenance dialysis patients during 2009 to 2013 in the Renji Hospital in Shanghai, China and in the San Bortolo Hospital in Vicenza, Italy were selected. Patients who changed their therapy from HD to PD or PD to HD during this study were excluded...
November 8, 2017: International Journal of Artificial Organs
https://www.readbyqxmd.com/read/29147572/association-of-neutrophil-to-lymphocyte-ratio-with-inflammation-and-erythropoietin-resistance-in-chronic-dialysis-patients
#17
Jérôme Pineault, Caroline Lamarche, Robert Bell, Jean-Philippe Lafrance, Georges Ouellet, Martine Leblanc, Vincent Pichette, Sarah Bezzaoucha, Michel Vallée
Background: Neutrophil-to-lymphocyte ratio (NLR) was widely studied as a prognostic marker in various medical and surgical specialties, but its significance in nephrology is not yet established. Objective: We evaluated its accuracy as an inflammation biomarker in a dialysis population. Design setting: Single-center retrospective study. Patients: The records of all 550 patients who were treated with hemodialysis (HD) or peritoneal dialysis (PD) from September 2008 to March 2011 were included...
2017: Canadian Journal of Kidney Health and Disease
https://www.readbyqxmd.com/read/29145203/evaluation-of-mental-disorders-using-proton-magnetic-resonance-spectroscopy-in-dialysis-and-predialysis-patients
#18
Chun-Yun Zhang, Ying Chen, Shan Chen, Xiang-Chuang Kong, Yuan Liu, Chao-Qun You, Cheng Wan, Philip A Bondzie, Hua Su, Chun Zhang, Fang-Fang He
BACKGROUND/AIMS: Psychological complications are prevalent in patients with chronic kidney disease (CKD). This study aimed to investigate mental disorders in stage 4-5 CKD patients, to detect metabolite concentrations in the brain by proton magnetic resonance spectroscopy (1H-MRS) and to compare the effects of different dialysis therapies on mental disorders in end-stage renal disease (ESRD). METHODS: The sample population was made up of predialysis (13), hemodialysis (HD) (13), and peritoneal dialysis (PD) patients (12)...
November 21, 2017: Kidney & Blood Pressure Research
https://www.readbyqxmd.com/read/29143935/a-propensity-matched-comparison-of-hard-outcomes-in-children-on-chronic-dialysis
#19
Enrico Vidal, Nicholas C Chesnaye, Fabio Paglialonga, Bruno Minale, Giovanna Leozappa, Mario Giordano, Bruno Gianoglio, Ciro Corrado, Rosa Maria Roperto, Roberto Chimenz, Francesca Mencarelli, Ilse-Maria Ratsch, Luisa Murer, Enrico Verrina
Data concerning outcomes of children on hemodialysis (HD) and peritoneal dialysis (PD) are scarce and frequently derived from single-center experiences. We sought to compare survival and transplantation rates in a large cohort of PD and HD patients. We extracted all patients initiating dialysis under 16 years of age between 2004 and 2013 from the Italian Registry of Pediatric Chronic Dialysis. Patients on PD were propensity-matched to those on HD based on gender, age, primary cause of ESRD, and the number of co-morbidities...
November 16, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29142964/impact-of-the-end-stage-renal-disease-prospective-payment-system-on-the-use-of-peritoneal-dialysis
#20
Qian Zhang, Mae Thamer, Onkar Kshirsagar, Yi Zhang
Introduction: The End Stage Renal Disease (ESRD) Prospective Payment System (PPS), implemented by the Centers for Medicare and Medicaid Services in January 2011, encouraged use of peritoneal dialysis (PD) through various financial incentives. Our goal was to determine whether PPS effectively increased PD use in incident dialysis patients. Methods: Our study used the United States Renal Data System (USRDS) to identify 430,927 adult patients who initiated dialysis between 2009 and 2012...
May 2017: KI Reports
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