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A V Prasolov, A S Kolbin, Yulia E Balykina
OBJECTIVES: To propose an algorithm that relates the effectiveness of drugs for a wide range of diseases with the financial capabilities of patients. METHODS: Estimates of the volume of pharmaceuticals that are consumed in the Russian Federation by all segments of the population regardless of household income were considered. These were calculated using statistically valid probabilities of the appearance of various diseases, official state data on the structure of expenditures of various strata of the population, and the optimal choice of the most effective medicines with income restrictions taken into account...
June 19, 2018: Value in Health Regional Issues
Luciana C Chiapella, Jorgelina Montemarani Menna, María Eugenia Mamprin
OBJECTIVE: This study aims to compare, both qualitatively and quantitatively, the medication dispensed to elderly patients in a primary health care center (PHC) and a community pharmacy (CP) in Argentina and to identify the prescription of potentially inappropriate medications (PIMs). METHODS: A cross-sectional observational study. Data were acquired from 886 prescriptions in the PHC and 2368 in the CP between February and April 2015. Dispensed medications were coded according to the Anatomical, Therapeutic, and Chemical (ATC) classification system...
June 19, 2018: Value in Health Regional Issues
Ramesh Sharma Poudel, Shakti Shrestha, Santosh Thapa, Bhupendra Kumar Poudel, Muniraj Chhetri
Background: Appropriate labeling of marketed medicines is necessary to fulfill the regulatory provisions and ensure patient medication safety. This study aimed to assess the primary labeling of medicines manufactured and marketed by Nepalese pharmaceutical industries. Methods: We assessed the primary labeling of all medicines available at the pharmacy of Chitwan Medical College Teaching Hospital (CMCTH), Chitwan, Nepal, between November 2017 to December 2017. Medicines were assessed as required by Drug Standard Regulation, 2043 (1986 AD) of Nepal...
2018: Journal of Pharmaceutical Policy and Practice
Peter W Inglis, Lorena R Mata, Marcos José da Silva, Roberto F Vieira, Rosa de B N Alves, Dijalma B Silva, Vânia C R Azevedo
Plants of the genus Phyllanthus, principally Phyllanthus amarus, Phyllanthus urinaria, Phyllanthus niruri , and Phyllanthus tenellus, are used in Brazilian folk medicine to treat kidney stones as well as other ailments, where the latter two species are listed in the Brazilian Pharmacopeia as quebra-pedra ( stone-breaker ). However, only P. niruri has been shown to be effective in a clinical setting. Nuclear ribosomal internal transcribed spacer (ITS1 - 5.8S rRNA-ITS2), internal transcribed spacer 2, and chloroplasts rbc L, mat K, psb A- trn H, trn L, and trn L- trn F were screened for their potential as DNA barcodes for the identification of 48 Phyllanthus taxa in Brazilian medicinal plant germplasm banks and in "living pharmacies"...
June 21, 2018: Planta Medica
Carolyn W Swenson, Neil S Kamdar, Kristian Seiler, Daniel M Morgan, Paul Lin, Sawsan As-Sanie
BACKGROUND: Opioids used for postoperative pain control after surgery have been associated with an increased risk of chronic opioid use. Hysterectomy is the most common major gynecologic procedure in the United States; however, we lack a data-driven definition of new persistent opioid use specific to hysterectomy. OBJECTIVE: 1) Determine a data-driven definition of new persistent opioid use among opioid naïve women undergoing hysterectomy; 2) Determine the prevalence of and risk factors for new persistent opioid use...
June 18, 2018: American Journal of Obstetrics and Gynecology
Yazed AlRuthia, Bander Balkhi, Marwan Alrasheed, Ahmed Altuwaijri, Mohammad Alarifi, Huda Alzahrani, Wael Mansy
This study aimed to explore the health beliefs and patterns of dietary supplement usage among fitness center members. This cross-sectional study was conducted in four large indoor fitness centers in Riyadh, Saudi Arabia. This study involved male fitness center members aged ≥18 years with no speech or hearing disabilities. In-person interviews were conducted with fitness center members who agreed to participate using a newly developed questionnaire. Information on participants' sociodemographics (e.g., age and education), smoking status, health status, exercise frequency, average time spent exercising, different supplements used, used supplements sources, and health beliefs regarding dietary supplements were obtained...
2018: PloS One
Aleksandra Milosavljevic, Trudi Aspden, Jeff Harrison
INTRODUCTION: Medication adherence can be defined as the extent to which one's medication-taking behaviour follows that mutually agreed upon by the prescribing physician. Optimal medication adherence is often deemed crucial for the success of a patient's treatment, as suboptimal adherence may lead to treatment failure and unnecessary medical expenditure. Increasing evidence has highlighted the positive contribution community pharmacist-led interventions can have on improving patients' adherence and health outcomes...
June 21, 2018: International Journal of Pharmacy Practice
Hamzah Alzubaidi, Ward Saidawi, Kevin Mc Namara
Background The benefits of professional pharmacy services in improving patient outcomes and reducing health expenditure are well documented. To a large extent, these services are not implemented in many developing countries. Objective To explore pharmacists' perceptions of and willingness to provide professional services in the United Arab Emirates (UAE) and the perceived barriers and facilitators. The current provision of pharmacy-based services and capacity for service delivery were also explored. Setting Community pharmacies in Sharjah and Dubai in the UAE...
June 20, 2018: International Journal of Clinical Pharmacy
Michael Reumerman, J Tichelaar, B Piersma, M C Richir, M A van Agtmael
OBJECTIVES: Pharmacovigilance education is essential since adverse drug reactions (ADRs) are a serious health problem and contribute to unnecessary patient burden and hospital admissions. Healthcare professionals have little awareness of pharmacovigilance and ADR reporting, and only few educational interventions had durable effects on this awareness. Our future healthcare providers should therefore acquire an adequate set of pharmacovigilance competencies to rationally prescribe, distribute, and monitor drugs...
June 20, 2018: European Journal of Clinical Pharmacology
Kashif Iqbal, Ya-Lin A Huang, Philip Peters, Paul Weidle, Karen Hoover
In 2012, antiretroviral (ARV) treatment guidelines expanded indications and recommended antiretroviral treatment for all HIV-infected persons in the United States, regardless of CD4 cell count. This analysis describes ARV prescriptions among commercially insured HIV-infected adults from 2012 to 2014. We analyzed persons aged 18-64 years from 2012 to 2014 Truven Health MarketScan Commercial Claims and Encounters® database. We identified HIV-infected persons who had at least one inpatient or two outpatient medical claims and identified pharmacy claims using National Drug Codes...
June 20, 2018: AIDS Care
Marieke M Ebbens, Sylvia A van Laar, Elsbeth J Wesselink, Kim B Gombert-Handoko, Patricia M L A van den Bemt
BACKGROUND: Pharmacy-led medication reconciliation in elective surgery patients is often performed at the preoperative screening (POS). Because of the time lag between POS and admission, changes in medication may lead to medication errors at admission (MEAs). In a previous study, a risk prediction model for MEA was developed. OBJECTIVE: To validate this risk prediction model to identify patients at risk for MEAs in a university hospital setting. METHODS: The risk prediction model was derived from a cohort of a Dutch general hospital and validated within a comparable cohort from a Dutch University Medical Centre...
June 1, 2018: Annals of Pharmacotherapy
Michael R Kraus, Henning Kleine, Stefanie Thönnes, Marc Pignot, Yuri Sanchez Gonzalez
INTRODUCTION: German data regarding the economic burden of chronic hepatitis C (CHC) and potential benefits of CHC treatment are limited. To address this issue, we evaluated the role of treatment in mitigating the economic burden of hepatic and extrahepatic complications (EHCs) from CHC virus infection in Germany. METHODS: This retrospective, cross-sectional study used claims data from the Betriebskrankenkasse German sickness fund (2007-2014) to assess the medical costs of hepatic complications and EHCs, including conditions that are prevalent and behavioral factors associated with CHC...
June 19, 2018: Infectious Diseases and Therapy
Michael R Kraus, Henning Kleine, Stefanie Thönnes, Marc Pignot, Yuri Sanchez Gonzalez
INTRODUCTION: German data regarding the burden of complications from chronic hepatitis C (CHC) virus infection are limited. To address this issue, this study evaluates the clinical and economic burden of hepatic and extrahepatic complications (EHCs) associated with CHC in Germany. METHODS: This retrospective, cross-sectional study used claims data from the Betriebskrankenkasse German sickness fund (2007-2014) to assess the risks and medical costs of hepatic complications and EHCs, including conditions that are prevalent and behavioral factors associated with CHC...
June 19, 2018: Infectious Diseases and Therapy
Mostafa A Sayed Ali, Eman Mohamed Hussein Khedr, Fatma Alzahraa Hassan Ahmed, Nada Nasr Eldin Mohamed
Background Drug-related problems (DRPs) are common in hospitalized patients with neurological diseases. Clinical pharmacy services could minimize drug-related harm and improve patient care. Objective To identify common DRPs in neurology and document clinical pharmacists' medication-related interventions. Setting The wards and intensive care unit of the Department of Neurology at Assiut University Hospital. Method Prospective study of clinical pharmacists' interventions during the routine care work of reviewing patients medical charts over a period of 6 months from January to June 2017...
June 19, 2018: International Journal of Clinical Pharmacy
Abbas Sheikhtaheri, Monireh Sadeqi-Jabali, Zahra Hashemi-Dehaghi
Background: To prevent health care errors, the main causes and preventive strategies should be identified. The purpose of this study was to identify the causes and preventive strategies of health care errors from the perspectives of physicians. Methods: We surveyed 250 randomly selected physicians in five teaching hospitals in Tehran, Iran, in 2015. We used a questionnaire with 29 questions regarding causes and 17 ones regarding the preventive strategies. The participants were asked to answer the questions based on Likert's five-point score (1=very low to 5= very high)...
May 2018: Iranian Journal of Public Health
Mohammed A Al-Qahtani, Hussein S Amin, Abdullah A Al-Qahtani, Abdullah M Alshahrani, Hani A Alghamdi, Musa S Althwayee, Ahmed A Alzahrani
OBJECTIVES: The objectives of this study are to estimate the prevalence of self-medication with antibiotics in King Khalid University Hospital population and evaluate the factors affecting this behavior. MATERIALS AND METHODS: This was a cross-sectional study conducted at King Khalid university hospital from April to May 2016. A pretested self-administered questionnaire was handed to a random selection of 519 patients attending the primary care clinics . Data were entered into Microsoft Office Excel 2007 and sent to SPSS version 20 for analysis...
May 2018: Journal of Family & Community Medicine
Wenjie Zhang, Tony B Amos, Stephen W Gutkin, Nicole Lodowski, Emma Giegerich, Kruti Joshi
Purpose: The aim of this study was to conduct a systematic literature review on the burden of schizophrenia in privately insured US patients. Materials and methods: A systematic literature review of English language peer-reviewed journal articles of observational studies published from 2006 to 2016 was conducted using EMBASE/MEDLINE databases. Abstracts covering substantial numbers of patients with schizophrenia or schizoaffective disorder (i.e., N ≥ 100) were included for full-text review...
2018: ClinicoEconomics and Outcomes Research: CEOR
Emilie Bettington, Jean Spinks, Fiona Kelly, Amanda J Wheeler
No abstract text is available yet for this article.
June 2018: Australian Prescriber
Audrey Valdes, Loic Epelboin, Emilie Mosnier, Gaelle Walter, Guillaume Vesin, Philippe Abboud, Alessia Melzani, Denis Blanchet, Nicaise Blaise, Mathieu Nacher, Magalie Demar, Felix Djossou
BACKGROUND: The preventive treatment of Plasmodium vivax relapse recommended by the World Health Organization is primaquine at a dose of 15 mg/day for 14 days, except for malaria cases from Asia and Oceania. Since 2006, CDC recommends the use of primaquine at 30 mg/day for 14 days. In France, all cases of malaria due to P. vivax are treated with 30 mg of primaquine. This systematically increased dosage needs to be evaluated according to epidemiological context. The aim of the study was to compare relapses after 14 days of primaquine at 15 or 30 mg/day...
June 19, 2018: Malaria Journal
Christopher S Russi, Alicia E Mattson, Peter A Smars, James S Newman, Alex J Beuning
We believe this is the first documented case of a critically ill patient managed by telepharmacy in a remote, rural critical access hospital. We outline the case and the benefits of telepharmacy in under-resourced, rural critical access emergency departments.
January 1, 2018: Journal of Telemedicine and Telecare
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