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https://www.readbyqxmd.com/read/29029106/iatrogenic-cushing-syndrome-in-a-child-with-congenital-adrenal-hyperplasia-erroneous-compounding-of-hydrocortisone
#1
Julia E Barillas, Daniel Eichner, Ryan Van Wagoner, Phyllis W Speiser
Context: Patients with 21-hydroxylase deficiency congenital adrenal hyperplasia (CAH) require lifelong treatment with glucocorticoids. In growing children the drug of choice is hydrocortisone. Commercially available hydrocortisone tablets do not conform to very low doses prescribed to infants and toddlers, and compounded hydrocortisone is often dispensed to meet therapeutic needs. However, safety, efficacy and uniformity of compounded products are not tested. We report a case of Cushing syndrome in a child with CAH who was inadvertently receiving excessive hydrocortisone in compounded form...
September 28, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29028563/exploring-the-relationship-between-online-buyers-and-sellers-of-image-and-performance-enhancing-drugs-ipeds-quality-issues-trust-and-self-regulation
#2
Katinka van de Ven, Rosa Koenraadt
BACKGROUND: Online drug markets are expanding the boundaries of drug supply including the sale and purchase of image and performance enhancing drugs (IPEDs). However, the role of the internet in IPED markets, and in particular the ways in which these substances are supplied via the surface web, has rarely been considered. This article examines the online IPED market in order to inform drug policy and to provide a nuanced understanding of retailers involved, particularly exploring the relationship between buyers and sellers...
October 10, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/29028437/stimulants-do-not-increase-the-risk-of-seizure-related-hospitalizations-in-children-with-epilepsy
#3
Xinyue Liu, Paul R Carney, Regina Bussing, Richard Segal, Linda B Cottler, Almut G Winterstein
OBJECTIVE: To evaluate the safety of stimulants in children with epilepsy. METHODS: In a retrospective cohort study based on Medicaid Analytic eXtract billing records from 26 U.S. states from 1999 to 2010, we identified incident stimulant use among children with epilepsy through outpatient encounter claims and pharmacy claims. We established a control group of nonusers and used frequency matching to generate index dates. We followed both cohorts for 12 months and calculated hazard ratios [HRs] of current and former use of stimulants versus no use on the outcome of seizure-related hospitalization using multivariate Cox proportional hazard models...
October 13, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/29028251/monitoring-surface-contamination-by-antineoplastic-drugs-in-italian-hospitals-performance-based-hygienic-guidance-values-hgvs-project
#4
Cristina Sottani, Elena Grignani, Enrico Oddone, Beatrice Dezza, Sara Negri, Simona Villani, Danilo Cottica
Antineoplastic drugs (ADs) will continue to represent a potential risk for personnel involved in the handling of these compounds and great concerns have been raised by the presence of ADs in many surveyed workplaces. Eight hospitals were investigated by means of wipe sampling for surface residue determination. Each wipe sample was tested for five ADs considered suitable exposure markers. Cyclophosphamide (CP), gemcitabine (GEM), 5-fluorouracil (5-FU), platinum-containing drugs (Pt), and epi-doxorubicin (EPI) contamination levels were measured in 85 per cent of the studied pharmacies and 93 per cent of outpatient care units (OpCUs)...
October 1, 2017: Annals of Work Exposures and Health
https://www.readbyqxmd.com/read/29027508/practice-based-small-group-learning-pbsgl-in-scotland-a-survey-of-registered-pharmacy-staff-and-general-practice-nurses
#5
David E Cunningham, Leon Zlotos
INTRODUCTION: Practice-based small group learning (PBSGL) has grown in primary healthcare in Scotland, and is used regularly by 2244 GPs and GP specialist trainees. The programme has been available to general practice nurses (GPNs) and pharmacy staff since uni-professional and inter-professional pilot studies were considered successful. Growth has been slower compared to GPs uptake but has now reached significant levels. It seemed timely to evaluate the use of the programme by these professions...
October 13, 2017: Education for Primary Care
https://www.readbyqxmd.com/read/29026844/an-interprofessional-collaboration-between-medicine-and-pharmacy-schools-designing-and-evaluating-a-teaching-program-on-practical-prescribing
#6
Mohammad Reza Javadi, Mina Khezrian, Anahita Sadeghi, Seyed Hossein Hajimiri, Kaveh Eslami
OBJECTIVE: Medical students need proper education in drug prescription. The aim of the present study is to introduce a course that improves the students' prescribing skills and also promotes an interprofessional collaboration between medicine and pharmacy schools. METHODS: This study was done in a skill laboratory at the pharmacotherapy department of Tehran University of Medical Sciences, Tehran, Iran. The course was an 18-h interactive workshop in 3 days under the supervision of clinical pharmacists...
July 2017: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/29026842/knowledge-attitude-and-practice-of-iranian-pharmacists-body-builders-and-their-coaches-regarding-sports-supplements
#7
Peivand Bastani, Ali Amjad Nia, Mohammadreza Shabanpoor, Safoora Mehravar, Sara Kashefian
OBJECTIVE: This study is conducted on Iranian pharmacists, coaches, and athletes regarding sports supplements to assess their knowledge, attitude, and practice (KAP) regarding sports supplements. METHODS: This was a cross-sectional study conducted in 2015. The study population consisted of all community pharmacists, bodybuilders, and bodybuilding coaches. The questionnaire was applied consisting some demographic questions and 25 questions for assessing KAP (6, 9, and 10, respectively)...
July 2017: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/29026602/re-phrasing-the-question-a-simple-tool-for-evaluation-of-adherence-to-therapy-in-patients-with-inflammatory-bowel-disease
#8
T Engel, B Ungar, G Ben-Haim, N Levhar, R Eliakim, S Ben-Horin
BACKGROUND: Non-adherence to medication in patients with inflammatory bowel disease (IBD) is a challenging problem which is often overlooked or under-estimated by the physician or denied by the patient. We aimed to examine if re-phrasing the wording of the question used by the physician could help in revealing more patients who are non-adherent, and for whom appropriate counseling may be instituted. METHODS: A cross-sectional questionnaire-based study of IBD patients treated in a tertiary center was conducted...
October 2017: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/29026296/trends-in-health-care-resource-utilization-and-pharmacological-management-of-copd-in-taiwan-from-2004-to-2010
#9
Ying-Huang Tsai, Tsung-Ming Yang, Chieh-Mo Lin, Shu-Yi Huang, Yu-Wen Wen
RATIONALE: COPD has attracted widespread attention worldwide. The prevalence of COPD in Taiwan has been reported, but little is known about trends in health care resource utilization and pharmacologic management in COPD treatment. OBJECTIVE: The objective of this article was to study trends in health care resource utilization, pharmacologic management, and medical costs of COPD treatment in Taiwan. MATERIALS AND METHODS: Reimbursement claims in the Taiwan National Health Insurance System from 2004 to 2010 were collected...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/29026250/thousands-of-new-oral-health-educators
#10
(no author information available yet)
Oral health promotion in the community pharmacy: an evaluation of a pilot oral health promotion intervention.
October 13, 2017: British Dental Journal
https://www.readbyqxmd.com/read/29025141/how-is-it-best-to-deliver-care-in-acute-medical-units-a-systematic-review
#11
L E M Reid, A J F Crookshanks, M C Jones, Z J Morrison, N I Lone, C J Weir
The majority of medical patients presenting to hospital in the UK are cared for in acute medical units (AMUs). Such units are also increasingly present internationally. Care delivery varies across units: this review aims to examine the evidence for how best to deliver AMU care.Six electronic databases and grey literature were searched. Inclusion criteria comprised interventions applied to undifferentiated patients in AMU settings. All studies were quality assessed. A narrative approach was undertaken.Nine studies, all conducted in the UK or Ireland, evaluated 1...
August 4, 2017: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/29025066/supply-and-demand-application-of-lean-six-sigma-methods-to-improve-drug-round-efficiency-and-release-nursing-time
#12
Maríosa Kieran, Mary Cleary, Aoife De Brún, Aileen Igoe
Objective: To improve efficiency, reduce interruptions and reduce the time taken to complete oral drug rounds. Design: Lean Six Sigma methods were applied to improve drug round efficiency using a pre- and post-intervention design. Setting: A 20-bed orthopaedic ward in a large teaching hospital in Ireland. Participants: Pharmacy, nursing and quality improvement staff. Intervention(s): A multifaceted intervention was designed which included changes in processes related to drug trolley organization and drug supply planning...
August 19, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/29024199/critical-care-pharmacy-workforce-uk-deployment-and-characteristics-in-2015
#13
Mark Borthwick, Greg Barton, Richard S Bourne, Catherine McKenzie
OBJECTIVE: Clinical pharmacists reduce medication errors and optimize the use of medication in critically ill patients, although actual staffing level and deployment of UK pharmacists is unknown. The primary aim was to investigate the UK deployment of the clinical pharmacy workforce in critical care and compare this with published standards. METHODS: An electronic data entry tool was created and distributed for UK critical care pharmacy services to record their critical care workforce deployment data...
October 11, 2017: International Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/29024057/increasing-candidemia-incidence-from-2004-to-2015-with-a-shift-in-epidemiology-in-patients-pre-exposed-to-antifungals
#14
Berdieke Goemaere, Pierre Becker, Eric Van Wijngaerden, Johan Maertens, Isabel Spriet, Marijke Hendrickx, Katrien Lagrou
BACKGROUND: Candidemia is an important health problem in immunocompromised patients with an epidemiology varying with region, period and patient population involved. OBJECTIVES: The occurrence of candidemia and the associated species distribution over a 12-year period at a large tertiary care centre in Belgium were analysed. The trend in incidence in the intensive care units (ICUs) and non-ICUs was investigated as well as the influence of antifungal exposure on the species distribution...
October 12, 2017: Mycoses
https://www.readbyqxmd.com/read/29024027/rural-disparities-in-alzheimer-s-disease-related-community-pharmacy-care-in-the-united-states
#15
Paul Jacob Henkel, Marketa Marvanova
PURPOSE: To examine the relationship between area population density and community pharmacy-based Alzheimer's Disease (AD)-related services: pharmacists' medication knowledge and counseling, immunizations, and in-stock cognitive enhancers in 3 predominantly rural regions of the United States. METHODS: A standardized interview was administered by telephone to a 100% sample of community pharmacies in 3 areas: Northern California/Southern Oregon (n = 206), North and South Dakota (n = 278), and West Virginia (n = 420)...
October 10, 2017: Journal of Rural Health
https://www.readbyqxmd.com/read/29023173/health-science-center-faculty-attitudes-towards-interprofessional-education-and-teamwork
#16
Jodie C Gary, Kevin Gosselin, Regina Bentley
The attitudes of faculty towards interprofessional education (IPE) and teamwork impact the education of health professions education (HPE) students. This paper reports on a study evaluating attitudes from health professions educators towards IPE and teamwork at one academic health science center (HSC) where modest IPE initiatives have commenced. Drawing from the results of a previous investigation, this study was conducted to examine current attitudes of the faculty responsible for the training of future healthcare professionals...
October 12, 2017: Journal of Interprofessional Care
https://www.readbyqxmd.com/read/29022823/impact-of-a-medication-reconciliation-program-on-cardiac-surgery-patients
#17
Abdulrazaq S Al-Jazairi, Lujain Khalid Al-Suhaibani, Rayd A Al-Mehizia, Salma Al-Khani, Glyn Lewis, Edward B De Vol, Elias Juan Saad
Background Cardiac surgery patients are at high risk of medication errors. Resumption of home medications reduces the significance and number of medication errors. This could be achieved by implementing a medication reconciliation program. Patients and Methods Patients were eligible for inclusion in this prospective study if they were admitted, transferred, and/or discharged under cardiac surgery team care from September 2015 to March 2016. The primary outcome was the number and proportion of unintentional medication discrepancies...
January 1, 2017: Asian Cardiovascular & Thoracic Annals
https://www.readbyqxmd.com/read/29022189/knowledge-perceptions-and-practice-of-ecopharmacovigilance-among-pharmacy-professionals-in-china
#18
Juan Liu, Jun Wang, Xian-Min Hu
Ecopharmacovigilance (EPV) is now a well-accepted critical component for the control of potential environmental risk posed by pharmaceutical residues. And improving the knowledge and perceptions about EPV, especially among pharmacy professionals, is the first step towards addressing the environmental impact of pharmaceuticals. This cross-sectional study was conducted to assess the knowledge, perceptions, and practice on EPV using a validated self-administered questionnaire delivered to a sample of 120 pharmacy professionals in Hubei Province, China...
October 11, 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/29021109/design-and-impact-of-bundled-payment-for-detox-and-follow-up-care
#19
Amity E Quinn, Dominic Hodgkin, Jennifer N Perloff, Maureen T Stewart, Mary Brolin, Nancy Lane, Constance M Horgan
INTRODUCTION: Recent payment reforms promote movement from fee-for-service to alternative payment models that shift financial risk from payers to providers, incentivizing providers to manage patients' utilization. Bundled payment, an episode-based fixed payment that includes the prices of a group of services that would typically treat an episode of care, is expanding in the United States. Bundled payment has been recommended as a way to pay for comprehensive SUD treatment and has the potential to improve treatment engagement after detox, which could reduce detox readmissions, improve health outcomes, and reduce medical care costs...
November 2017: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/29021008/medication-review-and-transitions-of-care-a-case-report-of-a-decade-old-medication-error
#20
Rachel Comer, Mitsi Lizer
A 69-year-old Caucasian male with a 25-year history of paranoid schizophrenia was brought to the emergency department because of violence toward the staff in his nursing facility. He was diagnosed with a urinary tract infection and was admitted to the behavioral health unit for medication stabilization. History included a five-year state psychiatric hospital admission and nursing facility placement. Because of poor cognitive function, the patient was unable to corroborate medication history, so the pharmacy student on rotation performed an in-depth chart review...
October 1, 2017: Consultant Pharmacist: the Journal of the American Society of Consultant Pharmacists
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