keyword
MENU ▼
Read by QxMD icon Read
search

Pdl

keyword
https://www.readbyqxmd.com/read/28079942/treatment-of-capillary-malformation-using-topical-timolol-combined-with-585-nm-pulsed-dye-laser-a-prospective-randomized-split-lesion-study
#1
Sang-Jin Cheon, Woo-Haing Shim, Gun-Wook Kim, Hoon-Soo Kim, Byung-Soo Kim, Moon-Bum Kim, Hyun-Chang Ko
Capillary malformation (CM) is a congenital vascular malformation characterized by the dilation of superficial dermal blood vessels.(1)  Currently, pulsed dye laser (PDL) is considered the gold standard for the treatment of CM.(1)  However, its use results in incomplete clearance despite multiple sessions and relapses during long-term follow-up.(1)  Alternative methods are needed to achieve improved therapeutic results. This article is protected by copyright. All rights reserved.
January 12, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28071181/cd8-t-cells-mediate-the-regenerative-pth-effect-in-hpdl-cells-via-wnt10b-signaling
#2
Michael Wolf, Stefan Lossdörfer, Jana Marciniak, Piero Römer, Christian Kirschneck, Rogerio Craveiro, James Deschner, Andreas Jäger
It was the aim of the present investigation to examine whether the stimulating effect of parathyroid hormone (PTH) on human periodontal ligament (hPDL) cell proliferation and differentiation would be enhanced by hPDL/T-cell interaction involving Wnt10b signaling as a mediating pathway. hPDL cells were cultured from healthy premolar tissues of three adolescent orthodontic patients and exposed to PTH(1-34) in monocultures or co-cultures with CD8(+) T cells. At harvest, proliferation, alkaline phosphatase-specific activity (ALP), and osteocalcin production were determined by immunofluorescence cytochemistry, real-time PCR, biochemical assay, and ELISA...
November 2016: Innate Immunity
https://www.readbyqxmd.com/read/28068493/bmp1-and-tll1-are-required-for-maintaining-periodontal-homeostasis
#3
J Wang, D Massoudi, Y Ren, A M Muir, S E Harris, D S Greenspan, J Q Feng
Mutations in bone morphogenetic protein 1 (BMP1) in humans or deletion of BMP1 and related protease tolloid like 1 (TLL1) in mice lead to osteogenesis imperfecta (OI). Here, we show progressive periodontal defects in mice in which both BMP1 and TLL1 have been conditionally ablated, including malformed periodontal ligament (PDL) (recently shown to play key roles in normal alveolar bone formation), significant loss in alveolar bone mass ( P < 0.01), and a sharp reduction in cellular cementum. Molecular mechanism studies revealed a dramatic increase in the uncleaved precursor of type I collagen (procollagen I) and a reduction in dentin matrix protein 1 (DMP1), which is partially responsible for defects in extracellular matrix (ECM) formation and mineralization...
January 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28067105/antimicrobial-effects-of-mastic-extract-against-oral-and-periodontal-pathogens
#4
Stefka Koychev, Henrik Dommisch, Hong Chen, Nicole Pischon
BACKGROUND: Various antimicrobial agents are widely used in the therapy of oral inflammatory diseases. However, their side effects and the appearance of drug resistance justify research on natural antimicrobial agents to target oral pathogens that are safe for the host. In the present study, antimicrobial properties of mastic extract on commensal and pathogenic oral bacteria, as well as its possible cytotoxic effect toward cells of epithelial and mesenchymal origin, were evaluated in comparison to the common antimicrobial agents hydrogen peroxide (H2O2) and chlorhexidine digluconate (CHX)...
January 8, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28066875/evaluating-the-effects-of-consolidation-on-intrusion-and-retraction-using-temporary-anchorage-devices-a-fem-study
#5
Monica Namburi, Sleevaraju Nagothu, Chetan S Kumar, N Chakrapani, C H Hanumantharao, Supradeep K Kumar
BACKGROUND: Extraction of premolars and retracting the anterior teeth using mini-implants and anterior retraction hooks became advent now a day. In such treatments, consolidation of arches is not done in regular practice. So, the present study is concentrated on effects of consolidation in two implant and three implant combinations of retraction and intrusion. METHODS: A three-dimensional FEM model of maxillary teeth and periodontal ligament housed in the alveolar bone with the first premolars extracted is generated with appropriate number of elements and nodes...
December 2017: Progress in Orthodontics
https://www.readbyqxmd.com/read/28061389/in-vitro-proliferation-of-periodontal-ligament-like-tissue-on-extracted-teeth
#6
T Iwata, C Mino, T Kawata
OBJECTIVE: Transplantation of autologous teeth is a routine component of orthodontic treatment. The aim of this study was to develop a method for the regeneration of damaged periodontal ligament (PDL) on extracted teeth using a three-dimensional culture system. DESIGN: We used the maxillary first premolars or third molars extracted from patients for orthodontic treatment. The extracted teeth were stained with toluidine blue to measure the residual PDL area. After confirming damage of the periodontal tissue on the root surface of the extracted teeth, we tried to regenerate the periodontal tissue...
November 30, 2016: Archives of Oral Biology
https://www.readbyqxmd.com/read/28056485/evidence-of-invasive-and-non-invasive-treatment-modalities-for-hypertrophic-scars-a-systematic-review
#7
Mona Kafka, Vanessa Collins, Lars-Peter Kamolz, Thomas Rappl, Ludwik K Branski, Paul Wurzer
Currently, there are various therapeutic approaches to reduce hypertrophic scarring, however, there is no standard evidence-based treatment protocol. Hence, we performed a systematic review to obtain a summary of the latest clinical trials to evaluate evidence for the treatment of hypertrophic scars. The review protocol was registered and approved by PROSPERO (CRD42015027040). PubMed and Web of Science were searched using predefined MeSH-Terms to identify studies published within the last 10 years regarding treatment for hypertrophic scars...
January 5, 2017: Wound Repair and Regeneration
https://www.readbyqxmd.com/read/28043177/the-pulsed-dye-laser-is-more-effective-and-rapidly-acting-than-intralesional-meglumine-antimoniate-therapy-for-cutaneous-leishmaniasis
#8
Mohammad Radmanesh, Ehsan Omidian
BACKGROUND AND OBJECTIVE: The Pulsed dye laser (PDL) is not tested yet for the treatment of cutaneous leishmaniasis (CL). We compared the efficacy of 585nm PDL with intralesional meglumine antimoniate (MA) on 17 patients with 81 lesions of cutaneous leishmaniasis. PATIENTS AND METHOD: Out of the 81 lesions, 42 lesions were treated with one or two passes of PDL fortnightly and 39 lesions in the same patients were treated with intralesional MA weekly. The fluence chosen for the laser was 7 Joules/cm2 with 5mm spot size...
January 3, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/28042260/effect-of-platelet-rich-plasma-concentrations-on-the-proliferation-of-periodontal-cells-an-in-vitro-study
#9
Sara Tavassoli-Hojjati, Mandana Sattari, Tayebeh Ghasemi, Rahil Ahmadi, Abbas Mashayekhi
OBJECTIVE: The purpose of this study was to evaluate the effect of different concentrations of platelet-rich plasma (PRP) on the proliferation of undifferentiated periodontal ligament (PDL) fibroblasts. MATERIALS AND METHODS: The undifferentiated PDL fibroblasts were obtained from two healthy human premolar teeth and cultured in Dulbecco's modified Eagle's medium. Cell wells were divided into five groups. Experimental groups received 0.1%, 5%, or 50% PRP; the positive and negative control groups were cultured in fetal bovine serum (FBS) 12% and in a medium without FBS 12%, respectively...
October 2016: European Journal of Dentistry
https://www.readbyqxmd.com/read/28035300/review-of-common-conditions-associated-with-periodontal-ligament-widening
#10
REVIEW
Hamed Mortazavi, Maryam Baharvand
PURPOSE: The aim of this article is to review a group of lesions associated with periodontal ligament (PDL) widening. MATERIALS AND METHODS: An electronic search was performed using specialized databases such as Google Scholar, PubMed, PubMed Central, Science Direct, and Scopus to find relevant studies by using keywords such as "periodontium", "periodontal ligament", "periodontal ligament space", "widened periodontal ligament", and "periodontal ligament widening"...
December 2016: Imaging Science in Dentistry
https://www.readbyqxmd.com/read/28000855/involvement-of-interleukin%C3%A2-23-induced-by-porphyromonas-endodontalis-lipopolysaccharide-in-osteoclastogenesis
#11
Nan Ma, Di Yang, Hirohiko Okamura, Jumpei Teramachi, Tomokazu Hasegawa, Lihong Qiu, Tatsuji Haneji
Periapical lesions are characterized by the destruction of periapical bone, and occur as a result of local inflammatory responses to root canal infection by microorganisms including Porphyromonas endodontalis (P. endodontalis). P. endodontalis and its primary virulence factor, lipopolysaccharide (LPS), are associated with the development of periapical lesions and alveolar bone loss. Interleukin‑23 (IL‑23) is critical in the initiation and progression of periodontal disease via effects on peripheral bone metabolism...
December 14, 2016: Molecular Medicine Reports
https://www.readbyqxmd.com/read/27995978/three-dimensional-ultrastructural-analysis-of-cells-in-the-periodontal-ligament-using-focused-ion-beam-scanning-electron-microscope-tomography
#12
Shingo Hirashima, Keisuke Ohta, Tomonoshin Kanazawa, Satoko Okayama, Akinobu Togo, Naohisa Uchimura, Jingo Kusukawa, Kei-Ichiro Nakamura
The accurate comprehension of normal tissue provides essential data to analyse abnormalities such as disease and regenerative processes. In addition, understanding the proper structure of the target tissue and its microenvironment may facilitate successful novel treatment strategies. Many studies have examined the nature and structure of periodontal ligaments (PDLs); however, the three-dimensional (3D) structure of cells in normal PDLs remains poorly understood. In this study, we used focused ion beam/scanning electron microscope tomography to investigate the whole 3D ultrastructure of PDL cells along with quantitatively analysing their structural properties and ascertaining their orientation to the direction of the collagen fibre...
December 20, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27995966/identification-of-an-evolutionary-conserved-structural-loop-that-is-required-for-the-enzymatic-and-biological-function-of-tryptophan-2-3-dioxygenase
#13
Helen Michels, Renée I Seinstra, Joost C M Uitdehaag, Mandy Koopman, Martijn van Faassen, Céline N Martineau, Ido P Kema, Rogier Buijsman, Ellen A A Nollen
The enzyme TDO (tryptophan 2,3-dioxygenase; TDO-2 in Caenorhabditis elegans) is a potential therapeutic target to cancer but is also thought to regulate proteotoxic events seen in the progression of neurodegenerative diseases. To better understand its function and develop specific compounds that target TDO we need to understand the structure of this molecule. In C. elegans we compared multiple different CRISPR/Cas9-induced tdo-2 deletion mutants and identified a motif of three amino acids (PLD) that is required for the enzymatic conversion of tryptophan to N-formylkynurenine...
December 20, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27993989/mohawk-transcription-factor-regulates-homeostasis-of-the-periodontal-ligament
#14
Naoki Koda, Tempei Sato, Masahiro Shinohara, Shizuko Ichinose, Yoshiaki Ito, Ryo Nakamichi, Tomohiro Kayama, Kensuke Kataoka, Hidetsugu Suzuki, Keiji Moriyama, Hiroshi Asahara
The periodontal ligament (PDL), which connects the teeth to the alveolar bone, is essential for periodontal tissue homeostasis. Although the significance of the PDL is recognized, molecular mechanisms underlying PDL function are not well-known. We report that Mohawk homeobox (Mkx), a tendon-specific transcription factor, regulates PDL homeostasis by preventing its degeneration. Mkx is expressed in the mouse PDL at the age of 10 weeks and 12 months. In Mkx(-/-) mice, age-dependent expansion of the PDL at the maxillary 1(st) molar (M1) furcation area was observed...
December 19, 2016: Development
https://www.readbyqxmd.com/read/27987427/importance-of-the-variable-periodontal-ligament-geometry-for-whole-tooth-mechanical-function-a-validated-numerical-study
#15
Anneke Nikolaus, John D Currey, Tom Lindtner, Claudia Fleck, Paul Zaslansky
When mammalian teeth breakdown food, several juxtaposed dental tissues work mechanically together, while balancing requirements of food comminution and avoiding damage to the oral tissues. One important way to achieve this is by channeling mastication forces into the surrounding jaw bone through a thin and compliant soft tissue, the periodontal ligament (PDL). As a result, during a typical chewing stroke, each tooth moves quite substantially in its anchor-site. Here we report a series of experiments, where we study the reaction of three-rooted teeth to a single chewing event by finite element (FE) modelling...
November 25, 2016: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/27987326/risk-factors-for-recurrence-after-successful-treatment-of-warts-the-role-of-smoking-habits
#16
P L Bencini, S Guida, S Cazzaniga, G Pellacani, M G Galimberti, M Bencini, L Naldi
BACKGROUND: Several therapies have been proposed for cutaneous warts without results concerning factors affecting recurrences. OBJECTIVE: To determine the importance of individual characteristics and different therapy modalities in the occurrence of relapses. METHODS: Observational prospective cohort study including 199 patients affected by multiple plantar warts treated as follows: 49 with keratolytics, 50 with CO2 laser, 50 with pulsed dye laser (PDL) and 50 with cryotherapy...
December 17, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27943593/coconut-milk-and-probiotic-milk-as-storage-media-to-maintain-periodontal-ligament-cell-viability-an-in-vitro-study
#17
Divya Saini, Prahlad Gadicherla, Prakash Chandra, Latha Anandakrishna
BACKGROUND/AIM: The viability of periodontal ligament (PDL) cells is a significant determinant of the long-term prognosis of replanted avulsed teeth. A storage medium is often required to maintain the viability of these cells during the extra-alveolar period. Many studies have been carried out to search for the most suitable storage medium for avulsed teeth, but an ideal solution has not yet been found. The purpose of the study was to compare and analyze the ability of coconut milk and probiotic milk to maintain PDL cell viability...
November 5, 2016: Dental Traumatology: Official Publication of International Association for Dental Traumatology
https://www.readbyqxmd.com/read/27942018/caspase-8-and-caspase-9-functioned-differently-at-different-stages-of-the-cyclic-stretch-induced-apoptosis-in-human-periodontal-ligament-cells
#18
Yaqin Wu, Dan Zhao, Jiabao Zhuang, Fuqiang Zhang, Chun Xu
BACKGROUND: Human periodontal ligament (PDL) cells underwent apoptosis after mechanical stretch loading. However, the exact signalling pathway remains unknown. This study aimed to elucidate how the apoptotic caspases functioned in the cyclic stretch-induced apoptosis in human PDL cells. MATERIALS AND METHODS: In the present study, 20% cyclic stretch was selected to load the cells for 6 or 24 h. The following parameters were analyzed: apoptotic rates, the protein levels of caspase-3, -7, -8 and -9 and the activities of caspase-8 and -9...
2016: PloS One
https://www.readbyqxmd.com/read/27940045/transfer-of-the-bone-morphogenetic-protein-4-gene-into-rat-periodontal-ligament-by-in-vivo-electroporation
#19
Shinobu Tsuchiya, Mirei Chiba, Koshi N Kishimoto, Harukazu Nakamura, Masahiro Tsuchiya, Haruhide Hayashi
OBJECTIVE: Regulation of alveolar bone metabolism is required in clinical dentistry. The aim of the present study was to establish a method for gene transfer into the periodontal ligament (PDL) by in vivo electroporation with a plasmid vector and to investigate the effects of BMP-4 transfer into the PDL. DESIGN: Plasmids containing mouse BMP-4 cDNA (pCAGGS-BMP4) were transfected into cultured rat PDL cells by in vitro electroporation, and BMP-4 production and secretion were detected by immunocytochemistry and western blotting...
February 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/27932407/torque-differences-according-to-tooth-morphology-and-bracket-placement-a-finite-element-study
#20
Spyridon N Papageorgiou, Iosif Sifakakis, Ludger Keilig, Raphael Patcas, Stefan Affolter, Theodore Eliades, Christoph Bourauel
INTRODUCTION: Torque of the maxillary incisors is essential in esthetics and proper occlusion, while torque expression is influenced by many factors. The aim of this finite element study was to assess the relative effect of tooth morphology, bracket prescription, and bracket positioning on tooth displacement and developed stresses/strains after torque application. METHODS: A three-dimensional upper right central incisor with its periodontal ligament (PDL) and alveolus was modelled...
December 8, 2016: European Journal of Orthodontics
keyword
keyword
12464
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"