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https://www.readbyqxmd.com/read/29619249/participation-restriction-and-assistance-needs-in-people-with-spinal-cord-injuries-of-more-than-40-year-duration
#1
Gordana Savic, Hans L Frankel, Mohamed Ali Jamous, Bakulesh M Soni, Susan Charlifue
Study design: Prospective observational. Objectives: Examine changes in participation restriction and assistance needs in a sample of people with long-standing spinal cord injuries (SCIs). Setting: Two British spinal centres. Methods: The sample consisted of British ageing with SCI study participants who were seen at baseline (1990 or 1993) and in the final follow-up (2010). Outcome measures were the Craig Handicap Assessment and Reporting Technique-Short Form (CHART-SF) and interview questions about assistance needs...
2018: Spinal Cord Series and Cases
https://www.readbyqxmd.com/read/29453362/long-term-bladder-and-bowel-management-after-spinal-cord-injury-a-20-year-longitudinal-study
#2
Gordana Savic, Hans L Frankel, Mohamed Ali Jamous, Bakulesh M Soni, Susan Charlifue
STUDY DESIGN: Prospective observational. AIM: The aim of this study was to analyse changes in bladder and bowel management methods in persons with long-standing spinal cord injury (SCI). SETTING: Two spinal centres in UK. METHOD: Data were collected through interviews and examinations between 1990 and 2010 in a sample of persons injured more than 20 years prior to 1990. RESULTS: For the 85 participants who completed the 2010 follow-up, the mean age was 67...
February 16, 2018: Spinal Cord
https://www.readbyqxmd.com/read/29434247/comparison-of-statistical-methods-for-calculating-life-expectancy-after-spinal-cord-injury
#3
Michael J DeVivo, Gordana Savic, Hans L Frankel, Mohamed Ali Jamous, Bakulesh M Soni, Susan Charlifue, James W Middleton, John Walsh
STUDY DESIGN: Retrospective observational. OBJECTIVES: To compare results of several different methods for calculating life expectancy in the same sample of people with spinal cord injury (SCI), and critically assess their advantages and disadvantages. SETTING: Two spinal centres in Great Britain. METHODS: Survival status of persons with traumatic SCI injured between 1943 and 2010 with follow-up to 2015 was determined...
February 12, 2018: Spinal Cord
https://www.readbyqxmd.com/read/29100544/effects-of-selected-palestinian-plants-on-the-in-vitro-exsheathment-of-the-third-stage-larvae-of-gastrointestinal-nematodes
#4
Rana Majed Jamous, Mohammed Saleem Ali-Shtayeh, Salam Yousef Abu-Zaitoun, Alex Markovics, Hassan Azaizeh
BACKGROUND: Gastrointestinal parasites are one of the main restrictions to small ruminant production. Their pathological importance is primarily related to the major production losses, in quantity or quality, induced by the direct action of worms. Control of these parasites is based exclusively on the frequent use of anthelmintic drugs. However, the resistance to anthelmintics in worm populations after commercialisation of chemical drugs is now widespread. Therefore, there is a need to find new natural resources to ensure sustainable and effective treatment and control of these parasites...
November 3, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28948966/suicide-and-traumatic-spinal-cord-injury-a-cohort-study
#5
G Savic, M J DeVivo, H L Frankel, M A Jamous, B M Soni, S Charlifue
STUDY DESIGN: Retrospective and prospective observational. OBJECTIVE: The main objective of this study was to analyse suicide attempt as a cause of traumatic spinal cord injury (tSCI) and suicide as a cause of death after tSCI. SETTING: This study was conducted at two British spinal centres, Stoke Mandeville and Southport. METHODS: Long-term survival of patients who were newly admitted between 1991 and 2010, had survived the first post-injury year and had neurological deficit on discharge...
January 2018: Spinal Cord
https://www.readbyqxmd.com/read/28674432/candidate-regulators-of-early-leaf-development-in-maize-perturb-hormone-signalling-and-secondary-cell-wall-formation-when-constitutively-expressed-in-rice
#6
Peng Wang, Shanta Karki, Akshaya K Biswal, Hsiang-Chun Lin, Mary Jacqueline Dionora, Govinda Rizal, Xiaojia Yin, Mara L Schuler, Tom Hughes, Jim P Fouracre, Basel Abu Jamous, Olga Sedelnikova, Shuen-Fang Lo, Anindya Bandyopadhyay, Su-May Yu, Steven Kelly, W Paul Quick, Jane A Langdale
All grass leaves are strap-shaped with a series of parallel veins running from base to tip, but the distance between each pair of veins, and the cell-types that develop between them, differs depending on whether the plant performs C3 or C4 photosynthesis. As part of a multinational effort to introduce C4 traits into rice to boost crop yield, candidate regulators of C4 leaf anatomy were previously identified through an analysis of maize leaf transcriptomes. Here we tested the potential of 60 of those candidate genes to alter leaf anatomy in rice...
July 3, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28647425/use-of-antibiotics-and-the-prevalence-of-antibiotic-associated-diarrhoea-in-patients-with-spinal%C3%A2-cord-injuries-an-international-multi-centre-study
#7
S Wong, P Santullo, S P Hirani, N Kumar, J R Chowdhury, A García-Forcada, M Recio, F Paz, I Zobina, S Kolli, C Kiekens, N Draulans, E Roels, J Martens-Bijlsma, J O'Driscoll, A Jamous, M Saif
BACKGROUND: Little is known about the use of antibiotics and the extent of antibiotic-associated diarrhoea (AAD) in patients with spinal cord injuries (SCIs). AIMS: To record the use of antibiotics, establish the prevalence of AAD and Clostridium difficile infection (CDI), and assess if there was any seasonal variation in antibiotic use and incidence of AAD in patients with SCIs. METHODS: A retrospective study was conducted in six European SCI centres between October 2014 and June 2015...
June 21, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28636849/extended-treatment-of-venous-thromboembolism
#8
LETTER
Fady Jamous
No abstract text is available yet for this article.
June 22, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28631749/causes-of-death-after-traumatic-spinal-cord-injury-a-70-year-british-study
#9
MULTICENTER STUDY
G Savic, M J DeVivo, H L Frankel, M A Jamous, B M Soni, S Charlifue
DESIGN: Retrospective and prospective observational. OBJECTIVE: Analyse causes of death after traumatic spinal cord injury (tSCI) in persons surviving the first year post injury, and establish any trend over time. SETTING: Two spinal centres in Great Britain. METHODS: The sample consisted of 5483 patients with tSCI admitted to Stoke Mandeville and Southport spinal centres who were injured between 1943 and 2010, survived first year post injury, had residual neurological deficit on discharge and were British residents...
October 2017: Spinal Cord
https://www.readbyqxmd.com/read/28619028/in-vitro-downregulated-hypoxia-transcriptome-is-associated-with-poor-prognosis-in-breast-cancer
#10
Basel Abu-Jamous, Francesca M Buffa, Adrian L Harris, Asoke K Nandi
BACKGROUND: Hypoxia is a characteristic of breast tumours indicating poor prognosis. Based on the assumption that those genes which are up-regulated under hypoxia in cell-lines are expected to be predictors of poor prognosis in clinical data, many signatures of poor prognosis were identified. However, it was observed that cell line data do not always concur with clinical data, and therefore conclusions from cell line analysis should be considered with caution. As many transcriptomic cell-line datasets from hypoxia related contexts are available, integrative approaches which investigate these datasets collectively, while not ignoring clinical data, are required...
June 15, 2017: Molecular Cancer
https://www.readbyqxmd.com/read/28290467/long-term-survival-after-traumatic-spinal-cord-injury-a-70-year-british-study
#11
G Savic, M J DeVivo, H L Frankel, M A Jamous, B M Soni, S Charlifue
STUDY DESIGN: Retrospective and prospective observational. OBJECTIVES: Analyse long-term survival after traumatic spinal cord injury (SCI) in Great Britain over the 70-year study period, identify mortality risk factors and estimate current life expectancy. SETTING: Two spinal centres in Great Britain. METHODS: The sample consisted of patients with traumatic SCI injured 1943-2010 who survived the first year post-injury, had residual neurological deficit on discharge and were British residents...
July 2017: Spinal Cord
https://www.readbyqxmd.com/read/28272917/candidate-gene-analysis-of-breast-cancer-in-the-jordanian-population-of-arab-descent-a-case-control-study
#12
Laith N Al-Eitan, Reem I Jamous, Rame H Khasawneh
This study aimed to investigate whether there are specific polymorphisms within six genes (BRCA1, BRCA2, TP53, DAPK1, MMP9 promoter, and TOX3) that are associated with breast cancer among the Jordanian population. Sequenom MassARRAY system was used to genotype 17 single nucleotide polymorphisms (SNPs) within these genes in 230 Jordanian breast cancer patients and 225 healthy individuals. Three SNPs (MMP9 (rs6065912), TOX3 (rs1420546), and DAPK1 (rs11141901) were found to be significantly associated with an increased risk of breast cancer (p < ...
April 21, 2017: Cancer Investigation
https://www.readbyqxmd.com/read/28139662/use-of-antibiotic-and-prevalence-of-antibiotic-associated-diarrhoea-in-patients-with-spinal-cord-injuries-a-uk-national-spinal-injury-centre-experience
#13
S Wong, P Santullo, J O'Driscoll, A Jamous, S P Hirani, M Saif
BACKGROUND: This was a retrospective audit, with the aims being to (1) record the use of antibiotics; (2) establish the prevalence of antibiotic-associated diarrhoea (AAD) and Clostridium difficile-associated diarrhoea (CDAD); and (3) assess if there was any seasonal variation in antibiotic use and incidence of AAD. METHODS: The study was performed at a single spinal cord injury (SCI) centre in the UK. Data were collected using a standardised questionnaire during October 2014 to June 2015...
June 2017: Spinal Cord
https://www.readbyqxmd.com/read/27972269/economic-analysis-of-evarrest-sealant-matrix-compared-with-standard-of-care-in-severe-soft-tissue-surgical-bleeding-a-france-hospital-perspective
#14
N Jamous, T N Thanh, N Ferko, A Hogan, J Batiller, R Kocharian, W Danker Iii
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27769165/distinct-gene-expression-program-dynamics-during-erythropoiesis-from-human-induced-pluripotent-stem-cells-compared-with-adult-and-cord-blood-progenitors
#15
Alison T Merryweather-Clarke, Alex J Tipping, Abigail A Lamikanra, Rui Fa, Basel Abu-Jamous, Hoi Pat Tsang, Lee Carpenter, Kathryn J H Robson, Asoke K Nandi, David J Roberts
BACKGROUND: Human-induced pluripotent stem cells (hiPSCs) are a potentially invaluable resource for regenerative medicine, including the in vitro manufacture of blood products. HiPSC-derived red blood cells are an attractive therapeutic option in hematology, yet exhibit unexplained proliferation and enucleation defects that presently preclude such applications. We hypothesised that substantial differential regulation of gene expression during erythroid development accounts for these important differences between hiPSC-derived cells and those from adult or cord-blood progenitors...
October 21, 2016: BMC Genomics
https://www.readbyqxmd.com/read/27703386/a-hospital-cost-analysis-of-a-fibrin-sealant-patch-in-soft-tissue-and-hepatic-surgical-bleeding
#16
Mitra Corral, Nicole Ferko, Andrew Hogan, Sarah S Hollmann, Gaurav Gangoli, Nadine Jamous, Jonathan Batiller, Richard Kocharian
BACKGROUND: Despite hemostat use, uncontrolled surgical bleeding is prevalent. Drawbacks of current hemostats include limitations with efficacy on first attempt and suboptimal ease-of-use. Evarrest(®) is a novel fibrin sealant patch that has demonstrated high hemostatic efficacy compared with standard of care across bleeding severities. The objective of this study was to conduct a hospital cost analysis of the fibrin sealant patch versus standard of care in soft tissue and hepatic surgical bleeding...
2016: ClinicoEconomics and Outcomes Research: CEOR
https://www.readbyqxmd.com/read/27596928/towards-tunable-consensus-clustering-for-studying-functional-brain-connectivity-during-affective-processing
#17
Chao Liu, Basel Abu-Jamous, Elvira Brattico, Asoke K Nandi
In the past decades, neuroimaging of humans has gained a position of status within neuroscience, and data-driven approaches and functional connectivity analyses of functional magnetic resonance imaging (fMRI) data are increasingly favored to depict the complex architecture of human brains. However, the reliability of these findings is jeopardized by too many analysis methods and sometimes too few samples used, which leads to discord among researchers. We propose a tunable consensus clustering paradigm that aims at overcoming the clustering methods selection problem as well as reliability issues in neuroimaging by means of first applying several analysis methods (three in this study) on multiple datasets and then integrating the clustering results...
March 2017: International Journal of Neural Systems
https://www.readbyqxmd.com/read/27165932/waveform-analysis-of-intraspinal-pressure-after-traumatic-spinal-cord-injury-an-observational-study-o-64
#18
Marek Czosnyka, Georgios V Varsos, Zofia H Czosnyka, Piotr Smielewski, Samira Saadoun, Ali Jamous, B Anthony Bell, Argyro Zoumprouli, Melissa C Werndle, Marios C Papadopoulos
Following a traumatic brain injury (TBI), intracranial pressure (ICP) increases, often resulting in secondary brain insults. After a spinal cord injury, here the cord may be swollen, leading to a local increase in intraspinal pressure (ISP). We hypothesised that waveform analysis methodology similar to that used for ICP after TBI may be applicable for the monitoring of patients with spinal cord injury.An initial cohort of 10 patients with spinal cord injury, as presented by the first author at a meeting in Cambridge in May 2012, were included in this observational study...
2016: Acta Neurochirurgica. Supplement
https://www.readbyqxmd.com/read/27165930/measurement-of-intraspinal-pressure-after-spinal-cord-injury-technical-note-from-the-injured-spinal-cord-pressure-evaluation-study
#19
Melissa C Werndle, Samira Saadoun, Isaac Phang, Marek Czosnyka, Georgios Varsos, Zofia Czosnyka, Peter Smielewski, Ali Jamous, B Anthony Bell, Argyro Zoumprouli, Marios C Papadopoulos
Intracranial pressure (ICP) is routinely measured in patients with severe traumatic brain injury (TBI). We describe a novel technique that allowed us to monitor intraspinal pressure (ISP) at the injury site in 14 patients who had severe acute traumatic spinal cord injury (TSCI), analogous to monitoring ICP after brain injury. A Codman probe was inserted subdurally to measure the pressure of the injured spinal cord compressed against the surrounding dura. Our key finding is that it is feasible and safe to monitor ISP for up to a week in patients after TSCI, starting within 72 h of the injury...
2016: Acta Neurochirurgica. Supplement
https://www.readbyqxmd.com/read/27125594/complementary-and-alternative-medicine-use-among-cancer-patients-in-palestine-with-special-reference-to-safety-related-concerns
#20
Mohammed S Ali-Shtayeh, Rana M Jamous, Nihaya M Y Salameh, Rania M Jamous, Amneh M A Hamadeh
ETHNOPHARMACOLOGICAL RELEVANCE: The use of CAM including herbal medicine as the most preferred CAM modality, among cancer patients who are taking prescription medications has shown to be highly prevalent worldwide as well as in several Middle Eastern countries, with a high percentage of the patients do not disclose their CAM use to treating physician. AIM OF THE STUDY: The current study aimed to evaluate the patterns of CAM use among two cohorts of cancer patients in Palestine over a three-year period, and to identify socio-demographic factors that are associated with CAM use...
July 1, 2016: Journal of Ethnopharmacology
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