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https://www.readbyqxmd.com/read/27913383/traumatic-haemopneumothorax-and-whole-body-subcutaneous-emphysema-successful-use-of-a-small-bore-chest-drain
#1
Benjamin Hardy, Nicholas Sunderland, Mevan Perera, Kathryn Channing
A 56-year-old man presented having had two falls at home. He had a background of multiple sclerosis. After his second fall, during which he had fallen onto the toilet injuring his right chest, he was brought into the emergency department reporting pleuritic chest discomfort. Immediately evident was extensive swelling from his forehead to his thighs, which on palpation was found to be subcutaneous emphysema. A chest X-ray showed a large right-sided pneumothorax for which a chest drain was inserted. A CT revealed extensive surgical emphysema, pneumomediastinum, pneumoperitoneum and gas within the spinal canal...
December 2, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27903001/right-in-front-of-our-eyes-evolution-of-streptococcal-toxic-shock-syndrome-with-ischemic-optic-neuropathy
#2
Salaheldin M Elhamamsy, Mazen O Al-Qadi, Taro Minami, Marguerite Neill
INTRODUCTION: Toxic shock syndrome occurs from dysregulation of host inflammatory responses. Toxin- producing strains of Group A streptococcus cause TSS. Ischemic optic neuropathy rarely complicates septic shock. We present a rare case of streptococcal pharyngitis complicated by septic arthritis and TSS with reversible blindness due to non-arteritic ischemic optic neuropathy. CASE: A 28-year-old man drove to our ED with exudative pharyngitis. A rapid streptococcal test was positive...
December 1, 2016: Rhode Island Medical Journal
https://www.readbyqxmd.com/read/27900434/combination-of-microbiological-spectroscopic-and-molecular-docking-techniques-to-study-the-antibacterial-mechanism-of-thymol-against-staphylococcus-aureus-membrane-damage-and-genomic-dna-binding
#3
Lang-Hong Wang, Zhi-Hong Zhang, Xin-An Zeng, De-Ming Gong, Man-Sheng Wang
Thymol (2-isopropyl-5-methylphenol) is a natural ingredient used as flavor or preservative agent in food products. The antibacterial mechanism of thymol against Gram-positive, Staphylococcus aureus was investigated in this work. A total of 15 membrane fatty acids were identified in S. aureus cells by gas chromatography-mass spectrometry. Exposure to thymol at low concentrations induced obvious alterations in membrane fatty acid composition, such as decreasing the proportion of branched 12-methyltetradecanoic acid and 14-methylhexadecanoic acid (from 22...
November 29, 2016: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/27888224/massive-haemolysis-gas-forming-liver-abscess-and-sepsis-due-to-clostridium-perfringens-bacteraemia
#4
Rafael García Carretero, Marta Romero Brugera, Oscar Vazquez-Gomez, Noelia Rebollo-Aparicio
Clostridial soft tissue infections are infrequent, but can be life-threatening when associated with certain underlying conditions, such as immunosuppression or malignancy. When bacteraemia occurs, it can be accompanied by haemolysis. Only surgical removal of the focus of infection and early onset of antibiotic therapy can prevent a very poor outcome. We describe the case of a man aged 65 years who presented with sepsis, haemolysis and rapid worsening. The identification of a gas-forming liver abscess, the early percutaneous drainage and the prompt initiation of antibiotic treatment were the key factors in the outcome of this patient...
November 25, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27881097/ischaemic-stroke-and-clostridium-septicum-sepsis-and-meningitis-in-a-patient-with-occult-colon-carcinoma-a-case-report-and-review-of-the-literature
#5
Kosmas Macha, Antje Giede-Jeppe, Hannes Lücking, Roland Coras, Hagen B Huttner, Jürgen Held
BACKGROUND: Clostridium septicum is a rare cause of meningitis and brain abscess in children and adults. Gas production by the pathogen can lead to pneumocephalus and the overall mortality rate of Clostridium septicum CNS infection is as high as 74%. The most common entry site of the pathogen is the gastrointestinal tract. CASE PRESENTATION: We describe a 74-year-old man who presented with a left-sided cerebral infarction in the middle cerebral artery territory...
November 24, 2016: BMC Neurology
https://www.readbyqxmd.com/read/27870933/bioremediation-of-hydrocarbon-degradation-in-a-petroleum-contaminated-soil-and-microbial-population-and-activity-determination
#6
Manli Wu, Wei Li, Warren A Dick, Xiqiong Ye, Kaili Chen, David Kost, Liming Chen
Bioremediation of hydrocarbon degradation in petroleum-polluted soil is carried out by various microorganisms. However, little information is available for the relationships between hydrocarbon degradation rates in petroleum-contaminated soil and microbial population and activity in laboratory assay. In a microcosm study, degradation rate and efficiency of total petroleum hydrocarbons (TPH), alkanes, and polycyclic aromatic hydrocarbons (PAH) in a petroleum-contaminated soil were determined using an infrared photometer oil content analyzer and a gas chromatography mass spectrometry (GC-MS)...
November 18, 2016: Chemosphere
https://www.readbyqxmd.com/read/27869667/metabolomics-a-powerful-tool-for-agricultural-research
#7
REVIEW
He Tian, Sin Man Lam, Guanghou Shui
Metabolomics, which is based mainly on nuclear magnetic resonance (NMR), gas-chromatography (GC) or liquid-chromatography (LC) coupled to mass spectrometry (MS) analytical technologies to systematically acquire the qualitative and quantitative information of low-molecular-mass endogenous metabolites, provides a direct snapshot of the physiological condition in biological samples. As complements to transcriptomics and proteomics, it has played pivotal roles in agricultural and food science research. In this review, we discuss the capacities of NMR, GC/LC-MS in the acquisition of plant metabolome, and address the potential promise and diverse applications of metabolomics, particularly lipidomics, to investigate the responses of Arabidopsis thaliana, a primary plant model for agricultural research, to environmental stressors including heat, freezing, drought, and salinity...
November 17, 2016: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/27866471/distal-renal-tubular-acidosis-without-renal-impairment-after-use-of-tenofovir-a-case-report
#8
Kentaro Iwata, Manabu Nagata, Shuhei Watanabe, Shinichi Nishi
BACKGROUND: Tenofovir, one of antiretroviral medication to treat human immunodeficiency virus (HIV) infection, is known to cause proximal renal tubular acidosis such as Fanconi syndrome, but cases of distal renal tubular acidosis had never been reported. CASE PRESENTATION: A 20-year-old man with HIV infection developed nausea and vomiting without diarrhea after starting antiretroviral therapy. Arterial blood gas revealed non-anion-gap metabolic acidosis and urine test showed positive urine anion gap...
November 21, 2016: BMC Pharmacology & Toxicology
https://www.readbyqxmd.com/read/27862457/a-pts-eii-mutant-library-in-group-a-streptococcus-identifies-a-promiscuous-man-family-pts-transporter-influencing-sls-mediated-hemolysis
#9
Ganesh S Sundar, Emrul Islam, Kanika Gera, Yoann Le Breton, Kevin S McIver
The Group A Streptococcus (GAS, Streptococcus pyogenes) is a Gram-positive human pathogen that must adapt to unique host environments in order to survive. Links between sugar metabolism and virulence have been demonstrated in GAS, where mutants in the phosphoenolpyruvate-dependent phosphotransferase system (PTS) exhibited Streptolysin S (SLS)-mediated hemolysis during exponential growth. This early onset hemolysis correlated with an increased lesion size and severity in a murine soft tissue infection model when compared with parental M1T1 MGAS5005...
November 8, 2016: Molecular Microbiology
https://www.readbyqxmd.com/read/27825481/enterobacter-sp-i-3-a-bio-herbicide-inhibits-gibberellins-biosynthetic-pathway-and-regulates-abscisic-acid-and-amino-acids-synthesis-to-control-plant-growth
#10
Ramalingam Radhakrishnan, Jae-Man Park, In-Jung Lee
Very few bacterial species were identified as bio-herbicides for weed control. The present research was focused to elucidate the plant growth retardant properties of Enterobacter sp. I-3 during their interaction by determining the changes in endogenous photosynthetic pigments, plant hormones and amino acids. The two bacterial isolates I-4-5 and I-3 were used to select the superior bacterium for controlling weed seeds (Echinochloa crus-galli L. and Portulaca oleracea L.) germination. The post-inoculation of I-3 (Enterobacter sp...
December 2016: Microbiological Research
https://www.readbyqxmd.com/read/27825231/nonequilibrium-all-atom-molecular-dynamics-simulation-of-the-bubble-cavitation-and-application-to-dissociate-amyloid-fibrils
#11
Man Hoang Viet, Philippe Derreumaux, Phuong H Nguyen
The cavitation of gas bubbles in liquids has been applied to different disciplines in life and natural sciences, and in technologies. To obtain an appropriate theoretical description of effects induced by the bubble cavitation, we develop an all-atom nonequilibrium molecular-dynamics simulation method to simulate bubbles undergoing harmonic oscillation in size. This allows us to understand the mechanism of the bubble cavitation-induced liquid shear stress on surrounding objects. The method is then employed to simulate an Aβ fibril model in the presence of bubbles, and the results show that the bubble expansion and contraction exert water pressure on the fibril...
November 7, 2016: Journal of Chemical Physics
https://www.readbyqxmd.com/read/27821833/-pulmonary-carcinosarcoma-presenting-hemothorax-caused-by-pleural-invasion-report-of-a-case
#12
Nobukata Kazawa, Yuta Shibamoto, Yukiya Kitabayashi, Yumi Ishihara, Taeko Gotoh, Yuusuke Sawada, Ryo Inukai, Takashi Tsujimura, Hideo Hattori, Akio Niimi, Ryoichi Nakanishi, Masanori Kitaichi
A 71-year-old man presented with hemothorax with cough, sputa and worsening dyspnea. On chest X-ray and computed tomography(CT), a huge tumor in the right upper lobe with hematoma and small amount of gas suggesting hemopneumothorax was revealed. No apparent lymphadenopathy nor intrapulmonary metastases were observed. The tumor showed a little enhancement on the contrastenhanced CT. Then the resction of the tumor was performed, and the pathological evaluation revealed a carcionosarcoma (adenocarcinoma+osteosarcoma) pT3N0 (stage II B) G4 pl2...
November 2016: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/27798077/a-fatality-related-to-the-synthetic-opioid-u-47700-postmortem-concentration-distribution
#13
Iain M McIntyre, Ray D Gary, Sandra Joseph, Robert Stabley
In this case report, we present an evaluation of the distribution of postmortem concentrations of 3,4-dichloro-N-[2-(dimethylamino)cyclohexyl]-N-methylbenzamide (U-47700) in a fatality attributed principally to the drug. A man who had a history of drug abuse was found unresponsive and not breathing on his bed. Drug paraphernalia, indicating drug insufflation, was located in the decedent's room. Toxicology screening tests in peripheral blood initially identified U-47700 using an alkaline drug screen with gas chromatography-mass spectrometry (GC-MS) following solid-phase extraction...
October 26, 2016: Journal of Analytical Toxicology
https://www.readbyqxmd.com/read/27785143/pneumopericardium-as-a-non-small-cell-lung-carcinoma-complication
#14
Anna Kubisa, Anna Lesińska, Paweł Dec, Małgorzata Szewczak-Głodek, Leszek Kochanowski, Bartosz Kubisa, Grzegorz Feledyk, Michalina Czarnecka, Janusz Wójcik, Tomasz Grodzki
Below we present a case of a young man with symptoms of progressive weakness, fever, cough, rapid decrease in body weight and the presence of a tumor in the left axillary region. The chest radiography and echocardiography revealed gas bubbles in the pericardium. The more detailed diagnostics and computed tomography of the chest showed an infiltration of the left lung cavity and a fistula among the bronchus, pleural and pericardial cavities. Further diagnostics demonstrated that the pneumopericardium (diagnosed by means of chest radiograph and echocardiography) was a complication of a primary non-small-cell lung carcinoma...
September 2016: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
https://www.readbyqxmd.com/read/27785110/successful-closure-of-treatment-na%C3%A3-ve-flat-edge-type-ii-full-thickness-macular-hole-using-inverted-internal-limiting-membrane-flap-technique
#15
Nazimul Hussain, Anjli Hussain
OBJECTIVE: The objective of this study was to present the outcome of the internal limiting membrane (ILM) peeling flap technique for a treatment-naïve, flat edge (Type II), full-thickness macular hole (MH). METHODS: A 52-year-old man presented with complaints of decreased vision and seeing black spot. He was diagnosed to have a flat edge, full-thickness MH, which was confirmed by optical coherence tomography (OCT). He underwent 23G vitrectomy with brilliant blue G-assisted inverted ILM peeling with an inverted flap over the hole followed by fluid gas exchange...
2016: International Medical Case Reports Journal
https://www.readbyqxmd.com/read/27777535/open-conversion-after-aortic-endograft-infection-caused-by-colistin-resistant-carbapenemase-producing-klebsiella-pneumoniae
#16
Nunzio Montelione, Danilo Menna, Pasqualino Sirignano, Laura Capoccia, Wassim Mansour, Francesco Speziale
A 62-year-old man presented with fever, abdominal pain, and malaise 13 months after emergency endovascular aortic repair. Computed tomographic angiograms showed a periprosthetic fluid and gas collection, so infection was diagnosed. Open conversion was performed, involving endograft explantation and in situ aortic reconstruction. Cultures and the explanted prosthesis were positive for carbapenemase-producing Klebsiella pneumoniae, resistant to colistin. Because of the sparse data on endograft infections caused by this pathogen, we placed the patient on an empiric double-carbapenem regimen for 4 weeks...
October 2016: Texas Heart Institute Journal
https://www.readbyqxmd.com/read/27770244/higher-hair-nicotine-level-in-children-compared-to-mother-living-with-smoking-father-in-malaysia
#17
Nur Nadia Mohamed, See Ling Loy, Che Nin Man, Abdullah Al-Mamun, Hamid Jan Jan Mohamed
OBJECTIVES: The objectives of this study are to determine parental and children's hair nicotine levels, their relationships as well as to investigate the association of smoking status of the fathers with mothers' and children's hair nicotine. METHODS: A cross-sectional study design was conducted among 124 families who were participants of the Universiti Sains Malaysia Pregnancy Cohort Study. Both parents with their 2 years old children joined this study. A total of 92 hair samples of fathers, 124 hair samples of mothers and 111 hair samples of children were collected and analyzed by gas chromatography-mass spectrometry...
November 2016: Environmental Health and Preventive Medicine
https://www.readbyqxmd.com/read/27761196/factitious-disorder-presenting-with-attempted-simulation-of-fournier-s-gangrene
#18
Joseph Tseng, Peter Poullos
Fournier's gangrene is a severe polymicrobial necrotizing fasciitis of the perineal, genital, or perianal regions. The classic presentation is severe pain and swelling with systemic signs. Crepitus and cutaneous necrosis are often seen. Characteristic CT findings include subcutaneous gas and inflammatory stranding. Unless treated aggressively, patients can rapidly become septic and die. Factitious Disorder is the falsification of one's own of medical or psychological signs and symptoms. Many deceptive methods have been described, from falsely reporting physical or psychological symptoms, to manipulating lab tests, or even injecting or ingesting foreign substances in order to induce illness...
September 2016: Journal of Radiology Case Reports
https://www.readbyqxmd.com/read/27742182/discriminating-circulatory-problems-from-deconditioning-echocardiogram-and-cardio-pulmonary-exercise-test-analysis
#19
Zach Rozenbaum, Shafik Khoury, Galit Aviram, Yaniv Gura, Jack Sherez, Avi Man, Jason Shimiaie, Thierry Le Tourneau, Amir Halkin, Simon Biner, Gad Keren, Yan Topilsky
BACKGROUND: Discriminating circulatory problems with reduced stroke volume from de-conditioning in which the muscles cannot consume O2 normally by gas exchange parameters is difficult. METHODS: We performed combined stress echo and cardio-pulmonary (CPET) tests in 110 patients (20 normal effort capacity, 54 attenuated stroke volume response, 36 de-conditioning) to evaluate multiple hemodynamic parameters and oxygen content difference (A-VO2 Difference) in four predefined activity levels to assess which of the gas measures may help in the discrimination...
October 11, 2016: Chest
https://www.readbyqxmd.com/read/27720974/gossypiboma-following-emergency-nephrectomy-for-wunderlich-syndrome
#20
Luis Gorospe, María Cristina González-Gordaliza, Javier García-Poza, Isabel García-Gómez-Muriel, Raquel García-Latorre
We describe the imaging findings of a case of an intraabdominal gossypiboma (retained surgical sponge) in an asymptomatic 61-year-old man who underwent an emergency nephrectomy because of a Wunderlich syndrome secondary to a renal cell carcinoma. A follow-up computed tomography (CT) was performed 4 months after the emergency surgery and showed an extraperitoneal lesion with gas bubbles and radiopaque markings in the left hemiabdomen, consistent with a retained surgical sponge ("gossypiboma" or "textiloma") in the anterior pararenal space...
October 6, 2016: Urology
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