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https://www.readbyqxmd.com/read/29659077/total-choline-quantification-measured-by-1h-mr-spectroscopy-as-early-predictor-of-response-after-neoadjuvant-treatment-for-locally-advanced-breast-cancer-the-impact-of-immunohistochemical-status
#1
Stylianos Drisis, Patrick Flamen, Michael Ignatiadis, Thierry Metens, Shih-Li Chao, Marie Chintinne, Marc Lemort
BACKGROUND: Validation of new biomarkers is essential for the early evaluation of neoadjuvant treatments. PURPOSE: To determine whether measurements of total choline (tCho) by 1H spectroscopy could predict morphological or pathological complete response (pCR) of neoadjuvant treatment and whether breast cancer subgroups are related to prediction accuracy. STUDY TYPE: Prospective, nonrandomized, monocentric, diagnostic study. POPULATION: Sixty patients were initially included with 39 women participating in the final cohort...
April 16, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29657610/detection-of-hepatocellular-carcinoma-by-tissue-resonance-interaction-method-trim
#2
Grzegorz Boryczka, Marek Hartleb, Małgorzata Janik
Introduction: Diagnosis of hepatocellular carcinoma (HCC) is considerably delayed, being frequently done in the non-curative stage of disease. The reason for delayed diagnosis is indolent course in early stages and/or unspecific symptoms indistinguishable from underlying cirrhosis. Hitherto methods used for screening of HCC have important limitations. TRIMprob is a non-invasive method, which showed utility in detection of cancers located in prostate, breast, or urinary bladder. Aim: To determine the diagnostic accuracy of TRIMprob in detecting HCC in cirrhotic liver...
2018: Przegla̜d Gastroenterologiczny
https://www.readbyqxmd.com/read/29656881/fundamentals-of-functional-imaging-i-current-clinical-techniques
#3
A Luna, T Martín Noguerol, L Alcalá Mata
Imaging techniques can establish a structural, physiological, and molecular phenotype for cancer, which helps enable accurate diagnosis and personalized treatment. In recent years, various imaging techniques that make it possible to study the functional characteristics of tumors quantitatively and reproducibly have been introduced and have become established in routine clinical practice. Perfusion studies enable us to estimate the microcirculation as well as tumor angiogenesis and permeability using ultrafast dynamic acquisitions with ultrasound, computed tomography, or magnetic resonance (MR) imaging...
April 12, 2018: Radiología
https://www.readbyqxmd.com/read/29652061/bevacizumab-and-near-infrared-probe-conjugated-iron-oxide-nanoparticles-for-vascular-endothelial-growth-factor-targeted-mr-and-optical-imaging
#4
Run Lin, Jing Huang, Liya Wang, Yuancheng Li, Malgorzata Lipowska, Hui Wu, Jianyong Yang, Hui Mao
Vascular endothelial growth factor (VEGF) plays a pivotal role in the cascade of development and progression of cancers. Targeting this cancer hallmark is a logical strategy for imaging based cancer detection and monitoring the anti-angiogenesis treatment. Using Bevacizumab (Avastin®), which is a recombinant humanized monoclonal antibody directly against VEGF and an angiogenesis inhibitor, as a targeting ligand, a multimodal VEGF targeted molecular imaging probe was developed by conjugating near infrared dye (NIR830) labeled bevacizumab to magnetic iron oxide nanoparticles (IONP) for optical and magnetic resonance (MR) imaging of cancers over-expressing VEGF...
April 13, 2018: Biomaterials Science
https://www.readbyqxmd.com/read/29650780/differentiating-atypical-hemangiomas-and-metastatic-vertebral-lesions-the-role-of-t1-weighted-dynamic-contrast-enhanced-mri
#5
K A Morales, J Arevalo-Perez, K K Peck, A I Holodny, E Lis, S Karimi
BACKGROUND AND PURPOSE: Vertebral hemangiomas are benign vascular lesions that are almost always incidentally found in the spine. Their classic typical hyperintense appearance on T1- and T2-weighted MR images is diagnostic. Unfortunately, not all hemangiomas have the typical appearance, and they can mimic metastases on routine MR imaging. These are generally referred to as atypical hemangiomas and can result in misdiagnosis and ultimately additional imaging, biopsy, and unnecessary costs...
April 12, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29649266/preoperative-dynamic-breast-magnetic-resonance-imaging-kinetic-features-using-computer-aided-diagnosis-association-with-survival-outcome-and-tumor-aggressiveness-in-patients-with-invasive-breast-cancer
#6
Sang Yu Nam, Eun Sook Ko, Yaeji Lim, Boo-Kyung Han, Eun Young Ko, Ji Soo Choi, Jeong Eon Lee
OBJECTIVES: To evaluate whether preoperative breast dynamic contrast-enhanced (DCE) magnetic resonance (MR) imaging kinetic features, assessed using computer-aided diagnosis (CAD), can predict survival outcome and tumor aggressiveness in patients with invasive breast cancer. MATERIALS AND METHODS: Between March and December 2011, 301 women who underwent preoperative DCE MR imaging for invasive breast cancer, with CAD data, were identified. All MR images were retrospectively evaluated using a commercially available CAD system...
2018: PloS One
https://www.readbyqxmd.com/read/29625821/improving-breast-mr-wait-times-a-model-for-transitioning-newly-implemented-diagnostic-imaging-procedures-into-routine-clinical-operation
#7
Colleen H Neal, Michelle D Sakala, Glenn E Houck, Mitra Noroozian, Ella A Kazerooni, Matthew S Davenport
PURPOSE: The purpose of this quality improvement (QI) initiative was to increase patient access to breast MR while maintaining diagnostic image quality. METHODS: Institutional review board approval was waived for this HIPAA-compliant QI initiative, which was conducted from December 2014 through March 2016. Breast MR wait times, scheduling grids, and staffing models were reviewed to identify root causes of elevated wait times. Breast MR wait times were tracked on a biweekly basis as root causes were identified and action plans were implemented...
April 4, 2018: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/29622173/impact-of-the-california-breast-density-law-on-screening-breast-mr-utilization-provider-ordering-practices-and-patient-demographics
#8
Shruthi Ram, Nandini Sarma, Javier E López, Yu Liu, Chin-Shang Li, Shadi Aminololama-Shakeri
PURPOSE: To assess the impact of California's Breast Density Law (BDL) on MRI utilization and clinician ordering practices. MATERIALS AND METHODS: Our institutional review board approved this study that retrospectively compared the ordering pattern for screening breast MRI examinations in the 30-month period before and after the BDL was enacted. Examinations were subcategorized into those with breast density mentioned as an examination indication. Patients were classified into (1) high risk; (2) above average risk, defined but not quantified; and (3) undefined or average risk...
April 2018: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/29622138/breast-mr-imaging-in-era-of-value-based-medicine
#9
EDITORIAL
Jessica W T Leung
No abstract text is available yet for this article.
May 2018: Magnetic Resonance Imaging Clinics of North America
https://www.readbyqxmd.com/read/29622137/breast-mr-imaging
#10
EDITORIAL
Lynne S Steinbach
No abstract text is available yet for this article.
May 2018: Magnetic Resonance Imaging Clinics of North America
https://www.readbyqxmd.com/read/29622136/american-college-of-radiology-accreditation-performance-metrics-reimbursement-and-economic-considerations-in-breast-mr-imaging
#11
REVIEW
Matthew F Covington, Catherine A Young, Catherine M Appleton
Accreditation through the American College of Radiology (ACR) Breast Magnetic Resonance Imaging Accreditation Program is necessary to qualify for reimbursement from Medicare and many private insurers and provides facilities with peer review on image acquisition and clinical quality. Adherence to ACR quality control and technical practice parameter guidelines for breast MR imaging and performance of a medical outcomes audit program will maintain high-quality imaging and facilitate accreditation. Economic factors likely to influence the practice of breast MR imaging include cost-effectiveness, competition with lower-cost breast-imaging modalities, and price transparency, all of which may lower the cost of MR imaging and allow for greater utilization...
May 2018: Magnetic Resonance Imaging Clinics of North America
https://www.readbyqxmd.com/read/29622135/how-does-mr-imaging-help-care-for-my-breast-cancer-patient-perspective-of-a-radiation-oncologist
#12
REVIEW
Kaitlin M Christopherson, Benjamin D Smith
Radiation therapy is used in many cases of both early and late breast cancer. The authors examine the role of MR imaging as it pertains to radiotherapy planning and treatment approaches for patients with breast cancer. MR imaging can assist the radiation oncologist in determining the best radiation approach and in creating treatment planning volumes. MR imaging may be useful in the setting of accelerated partial breast irradiation. Radiation oncologists should attend to MR breast images, when obtained, to ensure that these imaging findings are taken into consideration when developing a radiation therapy plan...
May 2018: Magnetic Resonance Imaging Clinics of North America
https://www.readbyqxmd.com/read/29622134/how-does-mr-imaging-help-care-for-the-breast-cancer-patient-perspective-of-a-medical-oncologist
#13
REVIEW
Akshara S Raghavendra, Debu Tripathy
Although traditional assessment with clinical examination, mammogram, and ultrasound is generally accepted for detection and staging of breast cancer, MR imaging is commonly used to detect occult cancers in the breast and regional nodes in the early stage and to determine the extent of disease in patients with metastatic disease. Several studies have shown a variety of uses for MR imaging in the staging of breast cancer and assessment of treatment response in the neoadjuvant (preoperative) setting. This article reviews the impact of MR imaging in different settings on medical oncology decision-making in patients with breast cancer...
May 2018: Magnetic Resonance Imaging Clinics of North America
https://www.readbyqxmd.com/read/29622133/how-does-mr-imaging-help-care-for-my-breast-cancer-patient-perspective-of-a-surgical-oncologist
#14
REVIEW
Benjamin Raber, Vivian J Bea, Isabelle Bedrosian
MR imaging is now readily available for surgeons to incorporate into their practice, thus, begging the question, is this new modality clinically useful? Current literature and expert opinion are reviewed concerning the implementation of breast MR imaging to clinical management of breast cancer. Although breast MR imaging is acknowledged to be highly sensitive in detection of breast cancer, its routine application to surgical practice remains controversial because these gains in sensitivity have not been demonstrated to translate into improved long-term patient outcomes...
May 2018: Magnetic Resonance Imaging Clinics of North America
https://www.readbyqxmd.com/read/29622132/comparison-of-breast-mr-imaging-with-molecular-breast-imaging-in-breast-cancer-screening-diagnosis-staging-and-treatment-response-evaluation
#15
REVIEW
Gaiane M Rauch, Beatriz E Adrada
Breast MR imaging and molecular breast imaging (MBI) are functional imaging modalities that can be used to noninvasively evaluate the pathophysiology and biology of breast cancer. In the era of personalized medicine, these imaging techniques give clinicians insight into cancer pathobiology and allows them to individualize treatment regimens. Breast MR imaging has gained acceptance for breast cancer evaluation; work is ongoing on validation of MBI for breast cancer evaluation. This article discusses clinical applications of breast MR imaging and MBI, and compares the performance of these techniques in breast cancer screening, diagnosis, staging, and treatment response evaluation...
May 2018: Magnetic Resonance Imaging Clinics of North America
https://www.readbyqxmd.com/read/29622131/use-of-breast-specific-pet-scanners-and-comparison-with-mr-imaging
#16
REVIEW
Deepa Narayanan, Wendie A Berg
The goals of this article are to discuss the role of breast-specific PET imaging of women with breast cancer, compare the clinical performance of positron emission mammography (PEM) and MR imaging for current indications, and provide recommendations for when women should undergo PEM instead of breast MR imaging.
May 2018: Magnetic Resonance Imaging Clinics of North America
https://www.readbyqxmd.com/read/29622130/comparison-of-contrast-enhanced-mammography-and-contrast-enhanced-breast-mr-imaging
#17
REVIEW
John Lewin
Contrast-enhanced mammography (CEM) is a contrast-enhanced modality for breast cancer detection that utilizes iodinated contrast and dual-energy imaging performed on a digital mammography unit with only slight modifications. It is approved by the US Food and Drug Administration, commercially available, and in routine clinical use at centers around the world. It has similar sensitivity and specificity to MR Imaging and has advantages in terms of cost, patient acceptability, and examination time. MR Imaging has some advantages compared with CEM, especially in its ability to image the complete axilla and the chest wall...
May 2018: Magnetic Resonance Imaging Clinics of North America
https://www.readbyqxmd.com/read/29622129/developments-in-breast-imaging-update-on-new-and-evolving-mr-imaging-and-molecular-imaging-techniques
#18
REVIEW
Samantha Lynn Heller, Laura Heacock, Linda Moy
This article reviews new developments in breast imaging. There is growing interest in creating a shorter, less expensive MR protocol with broader applicability. There is an increasing focus on and consideration for the additive impact that functional analysis of breast pathology have on identifying and characterizing lesions. These developments apply to MR imaging and molecular imaging. This article reviews evolving breast imaging techniques with attention to strengths, weaknesses, and applications of these approaches...
May 2018: Magnetic Resonance Imaging Clinics of North America
https://www.readbyqxmd.com/read/29622128/mr-imaging-guided-breast-interventions-indications-key-principles-and-imaging-pathology-correlation
#19
REVIEW
Lumarie Santiago, Rosalind P Candelaria, Monica L Huang
MR imaging is now routinely performed for breast cancer screening and staging. For suspicious MR imaging-detected lesions that are mammographically and sonographically occult, MR imaging-guided breast interventions, including biopsy, clip placement, and preoperative needle localization, have been developed to permit accurate tissue diagnosis and aid in surgical planning. These procedures are safe, accurate, and effective when performed according to key principles, including proper patient selection, use of appropriate technique, adequate preprocedure preparation and postprocedure patient care, and postprocedure imaging-pathology correlation...
May 2018: Magnetic Resonance Imaging Clinics of North America
https://www.readbyqxmd.com/read/29622127/problem-solving-mr-imaging-for-equivocal-imaging-findings-and-indeterminate-clinical-symptoms-of-the-breast
#20
REVIEW
Ethan Cohen, Jessica W T Leung
Breast MR imaging is commonly used for high-risk screening and for assessing the extent of disease in patients with newly diagnosed breast cancer, but its utility for assessing suspicious symptoms and equivocal imaging findings is less widely accepted. The authors review current literature and guidelines regarding the use of breast MR imaging for these indications. Overall, problem-solving breast MR imaging is best reserved for pathologic nipple discharge and sonographically occult architectural distortion with limited biopsy options...
May 2018: Magnetic Resonance Imaging Clinics of North America
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