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Farmer, Paul

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https://www.readbyqxmd.com/read/29119300/longitudinal-outcomes-of-children-with-pediatric-autoimmune-neuropsychiatric-disorder-associated-with-streptococcal-infections-pandas
#1
Jill Leon, Rebecca Hommer, Paul Grant, Cristan Farmer, Precilla D'Souza, Riley Kessler, Kyle Williams, James F Leckman, Susan Swedo
Little is known about the natural history of children with pediatric autoimmune neuropsychiatric disorder associated with streptococcal infections (PANDAS). This study prospectively followed 33 children with PANDAS for up to 4.8 years (mean 3.3 ± 0.7 years) after enrollment in a 24-week randomized, double-blind, placebo-controlled trial of intravenous immunoglobulin (IVIG) (N = 35). Fourteen of eighteen children randomized to placebo received open label IVIG 6 weeks after the blinded infusion, so follow-up results reported below largely reflect outcomes in a population of children who received at least one dose of IVIG...
November 8, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/29109569/-the-farmer-and-the-cowman-should-be-friends-surviving-a-curricular-revision-through-interprofessional-cooperation
#2
Timothy J Bloom, V Paul DiMondi
No abstract text is available yet for this article.
September 2017: American Journal of Pharmaceutical Education
https://www.readbyqxmd.com/read/29103648/adapting-crop-rotations-to-climate-change-in-regional-impact-modelling-assessments
#3
Edmar I Teixeira, John de Ruiter, Anne-Gaelle Ausseil, Adam Daigneault, Paul Johnstone, Allister Holmes, Andrew Tait, Frank Ewert
The environmental and economic sustainability of future cropping systems depends on adaptation to climate change. Adaptation studies commonly rely on agricultural systems models to integrate multiple components of production systems such as crops, weather, soil and farmers' management decisions. Previous adaptation studies have mostly focused on isolated monocultures. However, in many agricultural regions worldwide, multi-crop rotations better represent local production systems. It is unclear how adaptation interventions influence crops grown in sequences...
November 2, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29097432/endoscopic-ultrasound-fine-needle-aspiration-by-experienced-pulmonologists-a-cusum-analysis
#4
Paul Leong, Sheetal Deshpande, Louis B Irving, Philip G Bardin, Michael W Farmer, Barton R Jennings, Daniel P Steinfort
Endobronchial ultrasound transbronchial needle aspiration (EBUS TBNA) is an established, minimally invasive way to sample intrathoracic abnormalities. The EBUS scope can be passed into the oesophagus to perform endoscopic ultrasound with bronchoscope-guided fine-needle aspiration (EUS-B-FNA). In cases of suspected lung cancer, a combination of the two techniques is now recommended by consensus guidelines. EBUS TBNA is usually performed by pulmonologists; however, the learning curve for EUS-B-FNA, which may be performed during the same procedure, has not been described...
November 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29095802/occupational-exposure-to-vapor-gas-dust-and-fumes-in-a-cohort-of-rural-adults-in-iowa-compared-with-a-cohort-of-urban-adults
#5
COMPARATIVE STUDY
Brent C Doney, Paul K Henneberger, Michael J Humann, Xiaoming Liang, Kevin M Kelly, Jean M Cox-Ganser
PROBLEM/CONDITION: Many rural residents work in the field of agriculture; however, employment in nonagricultural jobs also is common. Because previous studies in rural communities often have focused on agricultural workers, much less is known about the occupational exposures in other types of jobs in rural settings. Characterizing airborne occupational exposures that can contribute to respiratory diseases is important so that differences between rural and urban working populations can be assessed...
November 3, 2017: MMWR. Surveillance Summaries: Morbidity and Mortality Weekly Report. Surveillance Summaries
https://www.readbyqxmd.com/read/29089292/tapering-practices-of-strongman-athletes-test-retest-reliability-study
#6
Paul W Winwood, Hayden J Pritchard, Justin Wl Keogh
BACKGROUND: Little is currently known about the tapering practices of strongman athletes. We have developed an Internet-based comprehensive self-report questionnaire examining the training and tapering practices of strongman athletes. OBJECTIVE: The objective of this study was to document the test-retest reliability of questions associated with the Internet-based comprehensive self-report questionnaire on the tapering practices of strongman athletes. The information will provide insight on the reliability and usefulness of the online questionnaire for use with strongman athletes...
October 31, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/29081595/the-effect-of-expected-value-on-attraction-effect-preference-reversals
#7
George D Farmer, Paul A Warren, Wael El-Deredy, Andrew Howes
The attraction effect shows that adding a third alternative to a choice set can alter preference between the original two options. For over 30 years, this simple demonstration of context dependence has been taken as strong evidence against a class of parsimonious value-maximising models that evaluate alternatives independently from one another. Significantly, however, in previous demonstrations of the attraction effect alternatives are approximately equally valuable, so there was little consequence to the decision maker irrespective of which alternative was selected...
October 2017: Journal of Behavioral Decision Making
https://www.readbyqxmd.com/read/29058943/a-re-examination-of-bias-in-human-randomness-perception
#8
Paul A Warren, Umberto Gostoli, George D Farmer, Wael El-Deredy, Ulrike Hahn
Human randomness perception is commonly described as biased. This is because when generating random sequences humans tend to systematically under- and overrepresent certain subsequences relative to the number expected from an unbiased random process. In a purely theoretical analysis we have previously suggested that common misperceptions of randomness may actually reflect genuine aspects of the statistical environment, once cognitive constraints are taken into account which impact on how that environment is actually experienced (Hahn & Warren, Psychological Review, 2009)...
October 23, 2017: Journal of Experimental Psychology. Human Perception and Performance
https://www.readbyqxmd.com/read/29045303/riluzole-serum-concentration-in-pediatric-patients-treated-for-obsessive-compulsive-disorder
#9
Paul Grant, Cristan Farmer, Jane Song, Timothy Kish, Susan Swedo
PURPOSE/BACKGROUND: The goals of this study were to determine whether pediatric serum concentration of riluzole is similar to that observed in adults and to determine whether riluzole serum concentration is associated with adverse effects or efficacy in children and adolescents with treatment-refractory obsessive-compulsive disorder. METHODS/PROCEDURES: Data were drawn from previously published studies: 1 open-label trial and 1 randomized controlled trial with an open-label extension phase...
December 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29032993/alleviating-the-access-abyss-in-palliative-care-and-pain-relief-an-imperative-of-universal-health-coverage-the-lancet-commission-report
#10
REVIEW
Felicia Marie Knaul, Paul E Farmer, Eric L Krakauer, Liliana De Lima, Afsan Bhadelia, Xiaoxiao Jiang Kwete, Héctor Arreola-Ornelas, Octavio Gómez-Dantés, Natalia M Rodriguez, George A O Alleyne, Stephen R Connor, David J Hunter, Diederik Lohman, Lukas Radbruch, María Del Rocío Sáenz Madrigal, Rifat Atun, Kathleen M Foley, Julio Frenk, Dean T Jamison, M R Rajagopal
No abstract text is available yet for this article.
October 11, 2017: Lancet
https://www.readbyqxmd.com/read/28952988/in-reply-to-eichbaum
#11
Joseph J Rhatigan, Paul E Farmer
No abstract text is available yet for this article.
October 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28935869/deoxyribonuclease-1-reduces-pathogenic-effects-of-cigarette-smoke-exposure-in-the-lung
#12
Paul T King, Roleen Sharma, Kim M O'Sullivan, Judy Callaghan, Lovisa Dousha, Belinda Thomas, Saleela Ruwanpura, Steven Lim, Michael W Farmer, Barton R Jennings, Michaela Finsterbusch, Gavin Brooks, Stavros Selemidis, Gary P Anderson, Stephen R Holdsworth, Philip G Bardin
Our aim was to investigate if deoxyribonuclease (DNase) 1 is a potential therapeutic agent to reduce pathogenic effects of cigarette smoke exposure in the lung. Cigarette smoke causes protease imbalance with excess production of proteases, which is a key process in the pathogenesis of emphysema. The mechanisms responsible for this effect are not well-defined. Our studies demonstrate both in vitro and in vivo that cigarette smoke significantly increases the expression of neutrophil and macrophage extracellular traps with coexpression of the pathogenic proteases, neutrophil elastase and matrix metalloproteinases 9 and 12...
September 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28882925/snap-2-epiccs-the-second-sprint-national-anaesthesia-project-epidemiology-of-critical-care-after-surgery-protocol-for-an-international-observational-cohort-study
#13
S Ramani Moonesinghe, Danny J N Wong, Laura Farmer, Richard Shawyer, Paul S Myles, Steve K Harris
INTRODUCTION: The admission of high-risk patients to critical care after surgery is a recommended standard of care. Nevertheless, poor compliance against this recommendation has been repeatedly demonstrated in large epidemiological studies. It is unclear whether this is due to reasons of capacity, equipoise, poor quality clinical care or because hospitals are working creatively to create capacity for augmented care on normal surgical wards. The EPIdemiology of Critical Care after Surgery study aims to address these uncertainties...
September 7, 2017: BMJ Open
https://www.readbyqxmd.com/read/28830045/climate-warming-causes-declines-in-crop-yields-and-lowers-school-attendance-rates-in-central-africa
#14
Trevon L Fuller, Paul R Sesink Clee, Kevin Y Njabo, Anthony Tróchez, Katy Morgan, Demetrio Bocuma Meñe, Nicola M Anthony, Mary Katherine Gonder, Walter R Allen, Rachid Hanna, Thomas B Smith
Although a number of recent studies suggest that climate associated shifts in agriculture are affecting social and economic systems, there have been relatively few studies of these effects in Africa. Such studies would be particularly useful in Central Africa, where the impacts of climate warming are predicted to be high but coincide with an area with low adaptive capacity. Focusing on plantain (Musa paradisiaca), we assess whether recent climate change has led to reduced yields. Analysis of annual temperature between 1950 and 2013 indicated a 0...
January 1, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/28816146/quality-assessment-of-stereotactic-radiosurgery-of-a-melanoma-brain-metastases-model-using-a-mouselike-phantom-and-the-small-animal-radiation-research-platform
#15
Cheng-Chia Wu, Kunal R Chaudhary, Yong Hum Na, David Welch, Paul J Black, Adam M Sonabend, Peter Canoll, Yvonne M Saenger, Tony J C Wang, Cheng-Shie Wuu, Tom K Hei, Simon K Cheng
PURPOSE: To establish a novel preclinical model for stereotactic radiosurgery (SRS) with combined mouselike phantom quality assurance in the setting of brain metastases. METHODS AND MATERIALS: C57B6 mice underwent intracranial injection of B16-F10 melanoma cells. T1-weighted postcontrast magnetic resonance imaging (MRI) was performed on day 11 after injection. The MRI images were fused with cone beam computed tomography (CBCT) images using the Small Animal Radiation Research Platform (SARRP)...
September 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28654847/a-model-comparison-approach-to-trauma-related-guilt-as-a-mediator-of-the-relationship-between-ptsd-symptoms-and-suicidal-ideation-among-veterans
#16
Katherine C Cunningham, Chloe Farmer, Stefanie T LoSavio, Paul A Dennis, Carolina P Clancy, Michael A Hertzberg, Claire F Collie, Patrick S Calhoun, Jean C Beckham
BACKGROUND: Suicidal ideation (SI) is a serious issue affecting U.S. veterans, and those with posttraumatic stress disorder (PTSD) are at an especially high risk of SI. Guilt has been associated with both PTSD and SI and may therefore be an important link between these constructs. METHODS: The present study compared models of trauma-related guilt and used path analysis to examine the direct and indirect effects of PTSD and trauma-related guilt on SI among a sample of 988 veterans receiving outpatient PTSD treatment at a Veterans Affairs (VA) specialty clinic...
October 15, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28648326/the-role-for-international-outreach-in-hand-surgery
#17
REVIEW
Karen Y Chung
Internationally, surgery is making its mark as a necessary priority in Low and Middle Income Countries (LMICs). In 2013, Paul Farmer, MD, and international leaders from 14 countries founded the Lancet Commission of Global Surgery to develop and assemble the best evidence on the state of surgery worldwide, to study the economics of surgical and anesthesia care delivery, and to develop strategies for improving access. Concurrently, there is growing interest in hand surgery. The Journal of Hand Surgery (European Volume) recently called for LMIC research with the goal of using their resources to improve the end product...
August 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/28641367/annual-crop-yield-variation-child-survival-and-nutrition-among-subsistence-farmers-in-burkina-faso
#18
Kristine Belesova, Antonio Gasparrini, Ali Sié, Rainer Sauerborn, Paul Wilkinson
Whether year to year variation in crop yields affects the nutrition, health, and survival of subsistence farming populations is relevant to the understanding of the potential impacts of climate change. However, the empirical evidence is limited. We examined the association of child survival with inter-annual variation in food crop yield and middle-upper arm circumference (MUAC) in a subsistence farming population of rural Burkina Faso. The study was of 44,616 children < 5 years of age included in the Nouna Health and Demographic Surveillance System, 1992-2012, whose survival was analysed in relation to the food crop yield in the year of birth (which ranged from 65% to 120% of the period average) and, for a subset of 16,698 children, to MUAC, using shared frailty Cox proportional hazards models...
June 21, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28629742/statistical-differences-in-the-white-matter-tracts-in-subjects-with-depression-by-using-different-skeletonized-voxel-wise-analysis-approaches-and-dti-fitting-procedures
#19
Maurizio Bergamino, Madison Farmer, Hung-Wen Yeh, Elisabeth Paul, J Paul Hamilton
Major depressive disorder (MDD) is one of the most significant contributors to the global burden of illness. Diffusion tensor imaging (DTI) is a procedure that has been used in several studies to characterize abnormalities in white matter (WM) microstructural integrity in MDD. These studies, however, have provided divergent findings, potentially due to the large variety of methodological alternatives available in conducting DTI research. In order to determine the importance of different approaches to coregistration of DTI-derived metrics to a standard space, we compared results from two different skeletonized voxel-wise analysis approaches: the standard TBBS pipeline and the Advanced Normalization Tools (ANTs) approach incorporating a symmetric image normalization (SyN) algorithm and a group-wise template (ANTs TBSS)...
June 16, 2017: Brain Research
https://www.readbyqxmd.com/read/28618042/farmers-knowledge-of-q-fever-and-prevention-approaches-in-new-south-wales
#20
Tony Lower, Paul Corben, Peter Massey, Julie Depczynski, Tony Brown, Priscilla Stanley, Margaret Osbourn, David Durrheim
OBJECTIVE: To identify what New South Wales (NSW) farmers know about Q fever to inform preventive approaches. DESIGN: Thematic analysis of qualitative data gathered through semi-structured individual interviews, focus groups and a community meeting. SETTING: Rural communities in NSW, Australia. PARTICIPANTS: A total of 25 farmers participated in individual interviews (n = 4) or three focus groups, each with seven participants (n = 21)...
June 15, 2017: Australian Journal of Rural Health
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