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https://www.readbyqxmd.com/read/29029120/diagnostic-usefulness-of-varicella-zoster-virus-real-time-pcr-with-dna-from-saliva-and-plasma-in-patients-with-herpes-zoster
#1
Seong Yeon Park, Ji Yeun Kim, Ji-Ae Kim, Jisoo Kwon, Sun-Mi Kim, Na Young Jeon, Min-Chul Kim, Yong Pil Chong, Sang Oh Lee, Sang-Ho Choi, Yang Soo Kim, Jun Hee Woo, Sung-Han Kim
Background: We evaluated the diagnostic usefulness of PCR for detecting varicella zoster virus (VZV) infection and reactivation of VZV using saliva and plasma VZV DNA from subjects suspected of having herpes zoster (HZ), and healthy volunteers exposed to stress, respectively. Methods: Study subjects were patients with HZ (n = 52), control patients with zoster-mimicking conditions (n = 30), and healthy university students (n = 27). VZV DNA was examined in saliva and plasma samples by real-time PCR...
September 26, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29028922/methods-for-handling-longitudinal-outcome-processes-truncated-by-dropout-and-death
#2
Lan Wen, Graciela Muniz Terrera, Shaun R Seaman
Cohort data are often incomplete because some subjects drop out of the study, and inverse probability weighting (IPW), multiple imputation (MI), and linear increments (LI) are methods that deal with such missing data. In cohort studies of ageing, missing data can arise from dropout or death. Methods that do not distinguish between these reasons for missingness typically provide inference about a hypothetical cohort where no one can die (immortal cohort). It has been suggested that inference about the cohort composed of those who are still alive at any time point (partly conditional inference) may be more meaningful...
September 26, 2017: Biostatistics
https://www.readbyqxmd.com/read/29028664/abacavir-use-and-risk-of-recurrent-myocardial-infarction-the-d-a-d-study
#3
Caroline A Sabin, Lene Ryom, Antonella d'Arminio Monforte, Camilla I Hatleberg, Christian Pradier, Wafaa El-Sadr, Ole Kirk, Rainer Weber, Andrew N Phillips, Amanda Mocroft, Fabrice Bonnet, Matthew Law, Stephane de Wit, Peter Reiss, Jens D Lundgren
OBJECTIVE: To investigate the association between abacavir (ABC) use and recurrent myocardial infarction (MI) among HIV-positive people with a prior MI. DESIGN: International multi-cohort collaboration with follow-up from 1999-2016. METHODS: The rate of recurrent MI was described among D:A:D participants who experienced an index MI whilst in the study, and who remained under follow-up beyond 28 days after this MI. Follow-up was considered to the date of next MI, death, 01/Feb/2016 or 6 months after last clinic visit...
October 12, 2017: AIDS
https://www.readbyqxmd.com/read/29028614/simultaneous-determination-of-five-alternaria-toxins-in-cereals-using-quechers-based-methodology
#4
Jian Zhou, Jiao-Jiao Xu, Zeng-Xuan Cai, Bai-Fen Huang, Mi-Cong Jin, Yi-Ping Ren
Two analytical approaches, including ultra-high performance liquid chromatograph linked with photo-diode array/fluorescence detector, and ultra-high performance liquid chromatography-tandem mass spectrometry, have been proposed for simultaneous determination of five Alternaria toxins in cereals, which both based on QuEChERS strategy. After QuEChERS extraction and salting out, the collected supernatant was subjected to an extra dispersive liquid-liquid microextraction step prior to quantitative analysis. Response surface methodology based on central composite design was employed to optimize the micro-extraction conditions...
October 4, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/29028082/evaluation-of-the-role-of-8-iso-pgf-levels-at-multiple-sites-during-intracranial-hemorrhage-in-pediatric-patients
#5
B-X Qi, H Yao, L Shang, L-P Sheng, X-C Wang, L Zhu, X-X Zhang, J-P Wang, D-H Fang
OBJECTIVE: The present study was planned to explore the role of 8-isomeric-prostaglandinF2α (8-iso-PGF2α) levels at the multiple sites of cerebrospinal fluid in children with intracranial hemorrhage. PATIENTS AND METHODS: 90 children with intracranial hemorrhage were admitted to Surgery Intensive Care Unit (SICU) of our hospital from January to December 2013 and were selected as study subjects. They were divided into group A (n=30), group B (n=30) and group C (n=30)...
September 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29028031/precise-identification-of-graphene-layers-at-the-air-prism-interface-via-a-pseudo-brewster-angle
#6
Chengquan Mi, Shizhen Chen, Weijie Wu, Wenshuai Zhang, Xinxing Zhou, Xiaohui Ling, Weixing Shu, Hailu Luo, Shuangchun Wen
We propose a simple method for the precise identification of graphene layers at the air-prism interface via a pseudo-Brewster angle, where the horizontally polarized reflection is close to zero. We find that the pseudo-Brewster angle is sensitive to the variation of graphene layers where the pseudo-Brewster angle is approximately linearly increased about 0.5 deg as the layer numbers increased. Furthermore, the sensitivity of the pseudo-Brewster angle can be greatly enhanced and reaches 0.04 deg by eliminating the influence of the cross-polarization effect...
October 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/29027735/temporal-trends-in-percutaneous-coronary-interventions-thru-the-drug-eluting-stent-era-insights-from-18-641-procedures-performed-over-12-year-period
#7
Uri Landes, Tamir Bental, Amos Levi, Abid Assali, Hana Vaknin-Assa, Eli I Lev, Eldad Rechavia, Gabriel Greenberg, Katia Orvin, Ran Kornowski
BACKGROUND: The last decade, regarded as the DES era in PCI, has witnessed significant advances in the management of coronary disease. We aimed to assess temporal trends in the practice and outcome of percutaneous coronary intervention (PCI) during the drug eluting stent (DES) era. METHODS: We analyzed 18,641 consecutive PCI's performed between January 2004 and December 2016, distinguished by procedural date (Q1 : 2004-2006, n = 4,865; Q2 : 2007-2009, n = 4,977; Q3 : 2010-2012, n = 4,230; Q4 : 2013-2016, n = 4,569)...
October 13, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29027715/diagnostic-performance-of-human-epididymis-protein-4-compared-to-a-combination-of-biophysical-and-biochemical-markers-to-differentiate-ovarian-endometriosis-from-epithelial-ovarian-cancer-in-premenopausal-women
#8
Tanja Nikolova, Radomir Zivadinovic, Nina Evtimovska, Violeta Klisarovska, Marko Stanojevic, Jadranka Georgievska, Natasha Nikolova
AIM: This study is a comparison of human epididymis protein 4 (HE4) with cancer antigen 125 (CA125), using the Risk of Ovarian Malignancy Algorithm (ROMA), Copenhagen Index (CPH-I), Risk of Malignancy Index (RMI) and Morphology Index (MI) to differentiate ovarian endometriosis from epithelial ovarian cancer (EOC) in premenopausal women. METHODS: The study was performed at the University Clinic of Obstetrics and Gynecology in Skopje. One hundred and sixty-four premenopausal patients were divided into three study groups, including ovarian endometriosis (37), other benign pelvic masses (57) and EOCs (11), and a control group (59)...
October 13, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29027652/correction-to-tumor-volume-doubling-time-as-a-dynamic-prognostic-marker-for-patients-with-hepatocellular-carcinoma
#9
Jong Kwan Kim, Hyung-Don Kim, Mi-Jung Jun, Sung-Cheol Yun, Ju Hyun Shim, Han Chu Lee, Danbi Lee, Jihyun An, Young-Suk Lim, Young-Hwa Chung, Yung Sang Lee, Kang Mo Kim
The original version of this article unfortunately contained an error in corresponding author e-mail. It was submitted and published as kimkim70@amc.seoul.kr instead of kimkm70@amc.seoul.kr.
October 13, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29027404/transvaginal-ultrasound-versus-magnetic-resonance-imaging-for-preoperative-assessment-of-myometrial-infiltration-in-patients-with-endometrial-cancer-a-systematic-review-and-meta-analysis
#10
Juan Luis Alcázar, Begoña Gastón, Beatriz Navarro, Rocío Salas, Juana Aranda, Stefano Guerriero
OBJECTIVE: To compare the diagnostic accuracy of transvaginal ultrasound (TVS) and magnetic resonance imaging (MRI) for detecting myometrial infiltration (MI) in endometrial carcinoma. METHODS: An extensive search of papers comparing TVS and MRI in assessing MI in endometrial cancer was performed in MEDLINE (PubMed), Web of Science, and Cochrane Database from January 1989 to January 2017. Quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2) tool...
November 2017: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/29026893/descending-necrotizing-mediastinitis-after-a-trigger-point-injection
#11
Jae Young Choe, Jong Kun Kim, Dong Eun Lee, Kang Suk Seo, Jung Bae Park, Mi Jin Lee, Hyun Wook Ryoo, Jae Yun Ahn, Sungbae Moon
Descending necrotizing mediastinitis (DNM) is a rare form of mediastinal infection. Most cases are associated with esophageal rupture. DNM after a trigger point injection in the upper trapezius has not been described previously. We present a case of DNM after a trigger point injection in the upper trapezius. A 70-year-old man visited the emergency department with chest discomfort and fever after a trigger point injection in the left upper trapezius. Chest computed tomography showed evidence of DNM, and antibiotic therapy was immediately administered intravenously...
September 2017: Clinical and Experimental Emergency Medicine
https://www.readbyqxmd.com/read/29026891/effect-of-emergency-medical-service-use-on-time-interval-from-symptom-onset-to-hospital-admission-for-definitive-care-among-patients-with-intracerebral-hemorrhage-a-multicenter-observational-study
#12
Dae Gon Kim, Yu Jin Kim, Sang Do Shin, Kyoung Jun Song, Eui Jung Lee, Yu Jin Lee, Ki Jeong Hong, Ju Ok Park, Young Sun Ro, Yoo Mi Park
OBJECTIVE: This study evaluated whether emergency medical service (EMS) use was associated with early arrival and admission for definitive care among intracerebral hemorrhage (ICH) patients. METHODS: Patients with ICH were enrolled from 29 hospitals between November 2007 and December 2012, excluding those patients with subarachnoid hemorrhage, traumatic ICH, and missing information. The patients were divided into four groups based on visit type to the definitive hospital emergency department (ED): direct visit by EMS (EMS-direct), direct visit without EMS (non-EMS-direct), transferred from a primary hospital by EMS (EMS-transfer), and transferred from a primary hospital without EMS (non-EMS-transfer)...
September 2017: Clinical and Experimental Emergency Medicine
https://www.readbyqxmd.com/read/29026711/glycated-hemoglobin-and-all-cause-mortality-in-korean-type-2-diabetes
#13
Mi Suk An, Sun A Kim, Jun-Ho Lee, Seong-Woo Choi, Min-Ho Shin
The purpose of this study was to evaluate the association between glycated hemoglobin (HbA1c) and all-cause mortality in type 2 diabetes mellitus. We conducted a community-based prospective cohort study of 352 type 2 diabetic patients aged 30-92 who participated in a community diabetes complications screening program in Gokseng-gun, Jeollanamdo, Korea. HbA1c levels were categorized as <6.5%, 6.5-6.9%, 7.0-7.9%, 8.0-8.9% and ≥9.0%. Patients were followed up on for a mean of 6.9 years. The Cox proportional hazards model was used to evaluate the relationship between HbA1c levels and all-cause mortality...
September 2017: Chonnam Medical Journal
https://www.readbyqxmd.com/read/29026552/the-discussion-of-t-1-17-p11-q21-translocation-in-acute-promyelocytic-leukemia-patient-on-molecular-remission
#14
Yannan Jia, Chengwen Li, Jiawei Zhao, Yang Song, Juan Wang, Yingchang Mi
Some chromosomal aberrations emerging in the course of treatment are probably not related to disease progression, but attribute to the germline alteration. Therefore, the dynamic genetic tests should be performed during the whole treatment process, which is significantly essential for efficacy evaluation and treatment decision- making.
October 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/29026413/evaluation-of-pentraxin-3-level-and-its-related-factors-in-patients-undergoing-primary-percutaneous-coronary-intervention
#15
Saeed Alipour-Parsa, Habib Haybar, Mohammad Hasan Namazi, Morteza Safi, Isa Khaheshi, Mehdi Memaryan, Amir Mohammad Eghbalnejad-Mofrad
BACKGROUND: Inflammation has an important role in the development and progression of atherosclerosis, and acute phase proteins such as pentraxin-3 (PTX3) can be deployed in determining the prognosis of coronary artery disease (CAD). So the purpose of this paper was to evaluate the PTX3 level and its related factors in patients undergoing primary percutaneous coronary intervention (PCI). METHODS: In this cross-sectional study, the PTX3 levels were determined for 100 patients with ST-elevation myocardial infarction referred to the Modarres Hospital, Tehran, Iran...
March 2017: ARYA Atherosclerosis
https://www.readbyqxmd.com/read/29026412/the-role-of-manual-thrombectomy-in-cardiovascular-outcome-among-patients-with-total-cutoff-vessel-myocardial-infarction-undergoing-primary-percutaneous-coronary-intervention
#16
Alireza Khosravi, Davoud Rajabi, Masoud Pourmoghaddas, Afzal Roohi, Masoumeh Esmaeili
BACKGROUND: The applicability of manual aspiration thrombectomy in patients with ST-segment elevation myocardial infarction (STEMI) has been a challenging issue. This study aimed to compare the impact of additive manual thrombectomy on patients with myocardial infarction (MI) and total cutoff vessel with standard primary percutaneous coronary intervention (PPCI) with bailout thrombectomy. METHODS: In this case-control study, 181 patients with acute STEMI were enrolled who referred to Chamran Hospital (Isfahan, Iran) between August to December 2014...
March 2017: ARYA Atherosclerosis
https://www.readbyqxmd.com/read/29026069/id3-regulates-the-mdc1-mediated-dna-damage-response-in-order-to-maintain-genome-stability
#17
Jung-Hee Lee, Seon-Joo Park, Gurusamy Hariharasudhan, Min-Ji Kim, Sung Mi Jung, Seo-Yeon Jeong, In-Youb Chang, Cheolhee Kim, Eunae Kim, Jihyeon Yu, Sangsu Bae, Ho Jin You
MDC1 plays a critical role in the DNA damage response (DDR) by interacting directly with several factors including γ-H2AX. However, the mechanism by which MDC1 is recruited to damaged sites remains elusive. Here, we show that MDC1 interacts with a helix-loop-helix (HLH)-containing protein called inhibitor of DNA-binding 3 (ID3). In response to double-strand breaks (DSBs) in the genome, ATM phosphorylates ID3 at serine 65 within the HLH motif, and this modification allows a direct interaction with MDC1. Moreover, depletion of ID3 results in impaired formation of ionizing radiation (IR)-induced MDC1 foci, suppression of γ-H2AX-bound MDC1, impaired DSB repair, cellular hypersensitivity to IR, and genomic instability...
October 12, 2017: Nature Communications
https://www.readbyqxmd.com/read/29025764/higher-risk-of-vascular-dementia-in-myocardial-infarction-survivors
#18
Jens Sundbøll, Erzsébet Hováth-Puhó, Kasper Adelborg, Morten Schmidt, Lars Pedersen, Hans Erik Bøtker, Victor W Henderson, Henrik T Sørensen
Background -Increased risk of dementia after myocardial infarction (MI) may be mediated by shared risk factors (e.g., atherosclerosis) and post-MI stroke. We examined risk of dementia in 1-year survivors of MI. Methods -Using Danish medical registries, we conducted a nationwide population-based cohort study of all patients with first-time MI and a sex-, birth year-, and calendar year-matched general population comparison cohort without MI (1980-2012). Cox regression analysis was used to compute 1-35 year adjusted hazard ratios (aHRs) for dementia, controlled for matching factors and adjusted for comorbidities and socioeconomic status...
October 12, 2017: Circulation
https://www.readbyqxmd.com/read/29025257/utility-of-the-national-lung-screening-trial-criteria-for-estimation-of-lung-cancer-in-the-korean-population
#19
Ye Jin Lee, Sun Mi Choi, Jinwoo Lee, Chang-Hoon Lee, Sang-Min Lee, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han, Young Sik Park
Purpose: Screening for lung cancer in high-risk patients using the National Lung Screening Trial (NLST) criteria resulted in a decreased lung cancer-related mortality rate. However, whether these criteria are applicable to the Korean has not been investigated thus far. Therefore, we estimated the utility of the NLST criteria as a screening tool for lung cancer in the Korean population. Materials and Methods: The total number of newly diagnosed lung cancer cases in 2013 was obtained from the Korea National Statistical Office...
October 12, 2017: Cancer Research and Treatment: Official Journal of Korean Cancer Association
https://www.readbyqxmd.com/read/29025209/delayed-diagnosis-of-pituitary-stalk-interruption-syndrome-with-severe-recurrent-hyponatremia-caused-by-adrenal-insufficiency
#20
Kyung Mi Jang, Cheol Woo Ko
Pituitary stalk interruption syndrome (PSIS) involves the occurrence of a thin or absent pituitary stalk, hypoplasia of the adenohypophysis, and ectopic neurohypophysis. Diagnosis is confirmed using magnetic resonance imaging. Patients with PSIS have a variable degree of pituitary hormone deficiency and a wide spectrum of clinical manifestations. The clinical course of the disease in our patient is similar to that of a syndrome of inappropriate antidiuretic hormone secretion. This is thought to be caused by failure in the suppression of vasopressin secretion due to hypocortisolism...
September 2017: Annals of Pediatric Endocrinology & Metabolism
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