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https://www.readbyqxmd.com/read/28432051/impact-of-study-outcome-on-submission-and-acceptance-metrics-for-peer-reviewed-medical-journals-six-year-retrospective-review-of-all-completed-glaxosmithkline-human-drug-research-studies
#1
Gary Evoniuk, Bernadette Mansi, Barbara DeCastro, Jennie Sykes
Objectives To determine whether the outcome of drug studies influenced submission and/or acceptance rates for publication in peer reviewed medical journals.Design A six year retrospective review of publication status by study outcome for all human drug research studies conducted by a single industry sponsor (GlaxoSmithKline) that completed from 1 January 2009 to 30 June 2014 and were therefore due for manuscript submission (per the sponsor's policy) to peer reviewed journals within 18 months of study completion-that is, 31 December 2015...
April 21, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28430936/preliminary-evaluation-of-the-niaaa-aap-brief-alcohol-use-screener
#2
Alan Meca, Jonathan G Tubman, Timothy Regan, Diane D Zheng, Rhoda Moise, Tae Kyoung Lee, Mary H Soares, Maria R Velazquez, Andrew Egbert, Seth J Schwartz
Aims: To assess the concurrent validity of the two-item NIAAA/American Academy of Pediatrics Brief Alcohol Use Screener, a developmentally sensitive assessment instrument, in a school-based sample of adolescents. Method: The sample consisted of 756 adolescents (53% girls; Mage = 13.7 years; SD = 1.6 years) in the 6th (n = 192), 8th (n = 283), and the 10th (n = 281) grades from Miami-Dade County, FL and Prince George's County, MD. Adolescents completed the NIAAA/AAP Brief Alcohol Use Screener, which consists of two items asking about adolescents' alcohol use and about peers' alcohol use during the last year...
May 1, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28429816/a-randomised-controlled-trial-to-test-the-effect-of-promoting-caregiver-contingent-talk-on-language-development-in-infants-from-diverse-socioeconomic-status-backgrounds
#3
Michelle McGillion, Julian M Pine, Jane S Herbert, Danielle Matthews
BACKGROUND: Early language skills are critical for later academic success. Lower socioeconomic status (SES) children tend to start school with limited language skills compared to advantaged peers. We test the hypothesis that this is due in part to differences in caregiver contingent talk during infancy (how often the caregiver talks about what is in the focus of the infant's attention). METHODS: In a randomised controlled trial with high and low SES families, 142 11-month olds and their caregivers were randomly allocated to either a contingent talk intervention or a dental health control...
April 21, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28426363/social-risk-and-protective-factors-in-adolescents-reduction-and-cessation-of-alcohol-use
#4
Tyrone C Cheng, Celia C Lo
BACKGROUND: Adolescents' alcohol use is related to many health problems, injuries, and violent acts, some with fatal consequences. A gap exists in the literature discussing risk/protective factors in change from non-heavy drinking to non-drinking, and also for change from heavy drinking to non-heavy drinking or non-drinking. OBJECTIVE: This secondary study examined some risk and protective factors involved when adolescent non-heavy drinkers and adolescent heavy drinkers curb or terminate their drinking...
June 7, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28422920/a-multi-year-assessment-of-a-hospital-school-program-to-promote-teen-motor-vehicle-safety
#5
Purnima Unni, Cristina M Estrada, Dai H Chung, Emily B Riley, Lesley Worsley-Hynd, Neil Stinson
BACKGROUND: Motor vehicle crashes are the leading cause of death among teen drivers. The main goal of this program was to reduce texting while driving among high school teens through a unique peer-generated anti-texting campaign. METHODS: The program consisted of two phases. In Phase 1, student leaders participated in a half-day, hospital-based experiential program that emphasized safe teen driving. In Phase 2, these students conceptualized and implemented an anti-texting while driving campaign during the school year...
April 18, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28422081/non-responsive-feeding-practices-unhealthy-eating-behaviors-and-risk-of-child-overweight-and-obesity-in-southeast-asia-a-systematic-review
#6
REVIEW
Ana Cristina Lindsay, Somporn Sitthisongkram, Mary L Greaney, Sherrie F Wallington, Praewrapee Ruengdej
Childhood obesity is increasing dramatically in many Southeast Asian countries, and becoming a significant public health concern. This review summarizes the evidence on associations between parental feeding practices, child eating behaviors, and the risk of overweight and obesity in Southeast Asian children 2-12 years old. We systematically searched five electronic academic/research (PubMed, PsycINFO, ProQuest Nursing, Medline, and CINAHL) databases using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement for peer-reviewed studies published in English between January 2000 and December 2016...
April 19, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28421645/grammaticality-differences-between-spanish-speaking-children-with-specific-language-impairment-and-their-typically-developing-peers
#7
Donna Jackson-Maldonado, Ricardo Maldonado
BACKGROUND: A limited number of studies have analyzed grammaticality in monolingual Spanish-speaking children with specific language impairment (SLI). Most of the available data are based on bilingual speakers. AIMS: To extend previous studies by doing a more detailed analysis of grammatical types in monolingual Spanish-speakers with and without SLI. METHODS & PROCEDURES: Forty-nine Spanish-speaking children (18 with SLI, 17 age-matched typically developing controls, 14 language-matched controls) were recruited from schools in Mexico and observed in a spontaneous narrative task...
April 18, 2017: International Journal of Language & Communication Disorders
https://www.readbyqxmd.com/read/28420664/the-uk-cardiac-and-vascular-surgery-interventional-anaemia-response-caviar-study-protocol-for-an-observational-cohort-study-to-determine-the-impact-and-effect-of-preoperative-anaemia-management-in-cardiac-and-vascular-surgical-patients
#8
Marisa Chau, Toby Richards, Caroline Evans, Anna Butcher, Timothy Collier, Andrew Klein
INTRODUCTION: Preoperative anaemia is linked to poor postsurgical outcome, longer hospital stays, greater risk of complications and mortality. Currently in the UK, some sites have developed anaemia clinics or pathways that use intravenous iron to correct iron deficiency anaemia prior to surgery as their standard of care. Although intravenous iron has been observed to be effective in a variety of patient settings, there is insufficient evidence in its use in cardiac and vascular patients...
April 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28420661/person-centred-transition-programme-to-empower-adolescents-with-congenital-heart-disease-in-the-transition-to-adulthood-a-study-protocol-for-a-hybrid-randomised-controlled-trial-stepstones-project
#9
Mariela Acuña Mora, Carina Sparud-Lundin, Ewa-Lena Bratt, Philip Moons
INTRODUCTION: When a young person grows up, they evolve from an independent child to an empowered adult. If an individual has a chronic condition, this additional burden may hamper adequate development and independence. Transition programmes for young persons with chronic disorders aim to provide the necessary skills for self-management and participation in care. However, strong evidence on the effects of these interventions is lacking. Therefore, as part of the STEPSTONES project (Swedish Transition Effects Project Supporting Teenagers with chrONic mEdical conditionS), we propose a trial to assess the effectiveness of a structured, person-centred transition programme to empower adolescents with congenital heart disease in the transition to adulthood...
April 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28418456/mapping-the-early-language-environment-using-all-day-recordings-and-automated-analysis
#10
Jill Gilkerson, Jeffrey A Richards, Steven F Warren, Judith K Montgomery, Charles R Greenwood, D Kimbrough Oller, John H L Hansen, Terrance D Paul
Purpose: This research provided a first-generation standardization of automated language environment estimates, validated these estimates against standard language assessments, and extended on previous research reporting language behavior differences across socioeconomic groups. Method: Typically developing children between 2 to 48 months of age completed monthly, daylong recordings in their natural language environments over a span of approximately 6-38 months...
April 16, 2017: American Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/28418329/phoneme-error-pattern-by-heritage-speakers-of-spanish-on-an-english-word-recognition-test
#11
Lu-Feng Shi
BACKGROUND: Heritage speakers acquire their native language from home use in their early childhood. As the native language is typically a minority language in the society, these individuals receive their formal education in the majority language and eventually develop greater competency with the majority than their native language. To date, there have not been specific research attempts to understand word recognition by heritage speakers. It is not clear if and to what degree we may infer from evidence based on bilingual listeners in general...
April 2017: Journal of the American Academy of Audiology
https://www.readbyqxmd.com/read/28415846/is-urban-rural-location-associated-with-weight-status-in-school-children-an-examination-of-42-small-and-rural-californian-counties
#12
Ron Strochlic, Lauren E Au, Lorrene Ritchie
INTRODUCTON: Studies have identified geographic variation in overweight and obesity rates among children, with higher rates of overweight and obesity often found among children living in rural compared to urban areas. A small number of studies have explored differences in overweight and obesity based on more nuanced gradations along the urban-rural continuum. The purpose of the present study was to identify differences in overweight and obesity based on gradations along the urban-rural continuum among children in 42 Californian counties with populations less than 500 000...
April 2017: Rural and Remote Health
https://www.readbyqxmd.com/read/28414737/peer-norm-guesses-and-self-reported-attitudes-towards-performance-related-pay
#13
Nikolaos Georgantzis, Efi Vasileiou, Iordanis Kotzaivazoglou
Due to a variety of reasons, people see themselves differently from how they see others. This basic asymmetry has broad consequences. It leads people to judge themselves and their own behavior differently from how they judge others and others' behavior. This research, first, studies the perceptions and attitudes of Greek Public Sector employees towards the introduction of Performance-Related Pay (PRP) systems trying to reveal whether there is a divergence between individual attitudes and guesses on peers' attitudes...
2017: PloS One
https://www.readbyqxmd.com/read/28412511/difference-in-neural-response-to-social-exclusion-observation-and-subsequent-altruism-between-adolescents-and-adults
#14
Béatrice Tousignant, Fanny Eugène, Katia Sirois, Philip L Jackson
Empathy and prosocial behaviors toward peers promote successful social development and creation of significant long-term relationships, but surprisingly little is known about the maturation of these skills during the period of adolescence. As the majority of studies have used questionnaires or pain observation paradigms, it remains unknown whether the empathic response of adolescents differs from that of adults in a paradigm that is closer to everyday life. In the current study, fMRI was used to examine the neural correlates of social exclusion observation and subsequent prosocial behavior in 20 adolescents (aged 12-17 years) and 20 adults (aged 22-30 years) while playing a ball-tossing game with what they believed to be real individuals...
April 12, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28412019/renal-function-in-relation-to-sodium-intake-a%C3%A2-quantitative-review-of-the-literature
#15
REVIEW
Kyoko Nomura, Kei Asayama, Lotte Jacobs, Lutgarde Thijs, Jan A Staessen
We undertook a quantitative literature review to search for evidence underpinning current guidelines proposing a reduction of sodium intake to less than 2.4 g/d for the management of chronic kidney disease. We searched PubMed for peer-reviewed articles published from January 1980 through May 2016. Two investigators screened 5072 publications and extracted data from 36, including 11 cross-sectional and 5 longitudinal observational studies and 20 intervention trials. Within-study effect sizes were pooled and standardized to a sodium gradient of 100 mmol/d by using inverse-variance weighted random effects models...
April 12, 2017: Kidney International
https://www.readbyqxmd.com/read/28411411/maternal-hypothyroxinaemia-in-early-pregnancy-and-problem-behavior-in-5-year-old-offspring
#16
Maurits H W Oostenbroek, Remco H J Kersten, Benjamin Tros, Anton E Kunst, Tanja G M Vrijkotte, Martijn J J Finken
INTRODUCTION: There is evidence, though not consistent, that offspring born to mothers with subtle decreases in thyroid function early in their pregnancies may be at risk of cognitive impairments and attention problems. However, other types of problem behavior have not been addressed thus far. We tested whether maternal thyroid function in early pregnancy is associated with several types of problem behavior in offspring at age 5-6 years. METHODS: This was a longitudinal study that included the data of 2000 mother-child pairs from the Amsterdam Born Children and their Development study...
March 25, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28409648/assessment-of-simulated-emergency-scenarios-are-trained-observers-necessary
#17
Juliane Noveanu, Felix Amsler, Wolfgang Ummenhofer, Thomas von Wyl, Mathias Zuercher
OBJECTIVES: Simulation-based medical training is associated with superior educational outcomes and improved cost efficiency. Self- and peer-assessment may be a cost-effective and flexible alternative to expert-led assessment. We compared accuracy of self- and peer-assessment of untrained raters using basic evaluation tools to expert assessment using advanced validation tools including validated questionnaires and post hoc video-based analysis. METHODS: Twenty-eight simulated emergency airway management scenarios were observed and video-recorded for further assessment...
April 14, 2017: Prehospital Emergency Care
https://www.readbyqxmd.com/read/28407754/effect-of-audit-and-feedback-with-peer-review-on-general-practitioners-prescribing-and-test-ordering-performance-a-cluster-randomized-controlled-trial
#18
J Trietsch, B van Steenkiste, R Grol, B Winkens, H Ulenkate, J Metsemakers, T van der Weijden
BACKGROUND: Much research worldwide is focussed on cost containment and better adherence to guidelines in healthcare. The research focussing on professional behaviour is often performed in a well-controlled research setting. In this study a large-scale implementation of a peer review strategy was tested on both test ordering and prescribing behaviour in primary care in the normal quality improvement setting. METHODS: We planned a cluster-RCT in existing local quality improvement collaboratives (LQICs) in primary care...
April 13, 2017: BMC Family Practice
https://www.readbyqxmd.com/read/28407491/uv-c-radiation-increases-sterol-production-in-the-microalga-pavlova-lutheri
#19
Faruq Ahmed, Peer M Schenk
Plant sterols have become well-known to promote cardiovascular health through the reduction of low density lipoprotein cholesterol in the blood. Plant sterols also have anti-inflammatory, anti-cancer, anti-oxidative and anti-atherogenicity activities. Microalgae have the potential to become a useful alternative source of plant sterols with several species reported to have higher concentrations than current commercial ones. In order to increase phytosterol production and optimise culture conditions, the high sterol producer Pavlova lutheri was treated in different dosages (50-250 mJ m(-2)) of UV-C radiation and several concentrations (1-500 μmol/L) of hydrogen peroxide (H2O2) and the sterol contents were quantified for two days after the treatments...
April 10, 2017: Phytochemistry
https://www.readbyqxmd.com/read/28406273/-we-are-part-of-a-family-benefits-and-limitations-of-community-art-groups-cags-in-thyolo-malawi-a-qualitative-study
#20
Umberto Pellecchia, Saar Baert, Spencer Nundwe, Andy Bwanali, Bote Zamadenga, Carol A Metcalf, Helen Bygrave, Sarah Daho, Liesbet Ohler, Brown Chibwandira, Kennedy Kanyimbo
INTRODUCTION: In 2012 Community ART Groups (CAGs), a community-based model of antiretroviral therapy (ART) delivery were piloted in Thyolo District, Malawi as a way to overcome patient barriers to accessing treatment, and to decrease healthcare workers' workload. CAGs are self-formed groups of patients on ART taking turns to collect ART refills for all group members from the health facility. We conducted a qualitative study to assess the benefits and challenges of CAGs from patients' and healthcare workers' (HCWs) perspectives...
March 28, 2017: Journal of the International AIDS Society
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