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https://www.readbyqxmd.com/read/28432611/comparison-of-human-erythrocyte-purine-nucleotide-metabolism-and-blood-purine-and-pyrimidine-degradation-product-concentrations-before-and-after-acute-exercise-in-trained-and-sedentary-subjects
#1
Wioleta Dudzinska, M Suska, A Lubkowska, K Jakubowska, M Olszewska, K Safranow, D Chlubek
This study aimed at evaluating the concentration of erythrocyte purine nucleotides (ATP, ADP, AMP, IMP) in trained and sedentary subjects before and after maximal physical exercise together with measuring the activity of purine metabolism enzymes as well as the concentration of purine (hypoxanthine, xanthine, uric acid) and pyrimidine (uridine) degradation products in blood. The study included 15 male elite rowers [mean age 24.3 ± 2.56 years; maximal oxygen uptake (VO2max) 52.8 ± 4.54 mL/kg/min; endurance and strength training 8...
April 21, 2017: Journal of Physiological Sciences: JPS
https://www.readbyqxmd.com/read/28431553/long-working-hours-in-the-healthcare-system-of-the-belo-horizonte-municipality-brazil-a-population-based-cross-sectional-survey
#2
Juliana M Andrade, Ada A Assunção, Mery N S Abreu
BACKGROUND: Health personnel are key players in developing and improving healthcare systems, caring for individuals and their communities, and helping improve quality of life. However, these professionals are often exposed to long working hours because of the pressing need for their services at potentially any time of day. The long working hours they endure are a major risk factor for both acute and chronic health problems. The present study aimed to analyze occurrences of long working hours and their association with individual characteristics and employment factors among workers in the municipal healthcare system in Belo Horizonte, Brazil...
April 21, 2017: Human Resources for Health
https://www.readbyqxmd.com/read/28431107/double-fixation-for-abdominal-aortic-aneurysm-repair-using-afx-body-and-endurant-proximal-aortic-cuff-mid-term-results
#3
Miltiadis I Matsagkas, George Kouvelos, Konstantinos Spanos, Athanasios Athanasoulas, Athanasios Giannoukas
Our goal was to evaluate the use of an AFX main body combined with an Endurant proximal aortic cuff to treat selected patients with an abdominal aortic aneurysm (AAA) associated with anatomical challenges, such as a small distal aortic diameter and a hostile aortic neck. A retrospective analysis of prospectively collected data from 2 vascular institutions identified 14 elective patients with an AAA (all men, 73.5 ± 5.1 years) treated with the AFX main body combined with an Endurant proximal aortic cuff...
April 17, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28430941/vagal-third-degree-atrioventricular-block-in-a-highly-trained-endurance-athlete
#4
Alejandro Vidal, Valentina Agorrody, Rodrigo Abreu, Pablo Viana, Alejandro Dodera, Luis Vidal
No abstract text is available yet for this article.
April 18, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28429081/cognitive-and-mood-improvements-following-acute-supplementation-with-purple-grape-juice-in-healthy-young-adults
#5
C F Haskell-Ramsay, R C Stuart, E J Okello, A W Watson
PURPOSE: Berry-derived phenolic compounds found in grapes have been associated with a number of health benefits, including the augmentation of human brain function and cognition. Previous intervention studies of Concord grape juice have demonstrated improvement to memory and driving ability following 3- to 4-month supplementation in middle-aged and older adults. However, no studies to date have demonstrated acute cognitive benefits of grape juice, and investigation of these effects in young adults is lacking...
April 20, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28428879/a-systems-biology-approach-to-investigating-the-influence-of-exercise-and-fitness-on-the-composition-of-leukocytes-in-peripheral-blood
#6
Michael P Gustafson, Ara Celi DiCostanzo, Courtney M Wheatley, Chul-Ho Kim, Svetlana Bornschlegl, Dennis A Gastineau, Bruce D Johnson, Allan B Dietz
BACKGROUND: Exercise immunology has become a growing field in the past 20 years, with an emphasis on understanding how different forms of exercise affect immune function. Mechanistic studies are beginning to shed light on how exercise may impair the development of cancer or be used to augment cancer treatment. The beneficial effects of exercise on the immune system may be exploited to improve patient responses to cancer immunotherapy. METHODS: We investigated the effects of acute exercise on the composition of peripheral blood leukocytes over time in a male population of varying fitness...
2017: Journal for Immunotherapy of Cancer
https://www.readbyqxmd.com/read/28428426/transgenerational-transmission-of-environmental-information-in-c-elegans
#7
Adam Klosin, Eduard Casas, Cristina Hidalgo-Carcedo, Tanya Vavouri, Ben Lehner
The environment experienced by an animal can sometimes influence gene expression for one or a few subsequent generations. Here, we report the observation that a temperature-induced change in expression from a Caenorhabditis elegans heterochromatic gene array can endure for at least 14 generations. Inheritance is primarily in cis with the locus, occurs through both oocytes and sperm, and is associated with altered trimethylation of histone H3 lysine 9 (H3K9me3) before the onset of zygotic transcription. Expression profiling reveals that temperature-induced expression from endogenous repressed repeats can also be inherited for multiple generations...
April 21, 2017: Science
https://www.readbyqxmd.com/read/28427544/what-s-the-secret-behind-the-benefits-of-whole-body-vibration-training-in-patients-with-copd-a-randomized-controlled-trial
#8
Rainer Gloeckl, Inga Jarosch, Ulrike Bengsch, Magdalena Claus, Tessa Schneeberger, Vasileios Andrianopoulos, Jeffrey W Christle, Wolfgang Hitzl, Klaus Kenn
BACKGROUND: Several studies have shown that whole-body vibration training (WBVT) improves exercise capacity in patients with severe COPD. The aim of this study was to investigate the determinants of improved exercise capacity following WBVT. METHODS: Seventy-four COPD patients (FEV1: 34 ± 9%predicted) were recruited during a 3-week inpatient pulmonary rehabilitation (PR) program. Conventional endurance and strength exercises were supplemented with self-paced dynamic squat training sessions (4bouts*2min, 3times/wk)...
May 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28426521/a-history-of-the-western-institute-of-nursing-and-its-communicating-nursing-research-conferences
#9
Paula A McNeil, Carol A Lindeman
BACKGROUND: The Western Institute of Nursing (WIN) celebrated its 60th anniversary and the 50th Annual Communicating Nursing Research Conference in April 2017. PURPOSE: The purpose of this article is to provide a brief history of the origin, development, and accomplishments of WIN and its Communicating Nursing Research conferences. APPROACH: Historical documents and conference proceedings were reviewed. SUMMARY: WIN was created in 1957 as the Western Council on Higher Education for Nursing under the auspices of the Western Interstate Commission for Higher Education...
April 20, 2017: Nursing Research
https://www.readbyqxmd.com/read/28426517/effects-of-betaine-supplementation-on-muscle-strength-and-power-a-systematic-review
#10
Ahmed Ismaeel
Betaine has recently gotten much attention for its potential role as an ergogenic aid and has become a common ingredient in peri-workout dietary supplements. The purpose of this systematic review of the literature was to investigate the effects of betaine supplementation on muscular strength and power. A computerized literature search of 3 databases (PubMed, MEDLINE, and Scopus) was performed. Included in the review were randomized controlled trials that measured muscle strength, power, and/or endurance in healthy participants...
April 15, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28426281/identification-of-ssea-1-expressing-enhanced-reprogramming-seer-cells-in-porcine-embryonic-fibroblasts
#11
Dong Li, Jan O Secher, Morten Juhl, Kaveh Mashayekhi, Troels T Nielsen, Bjørn Holst, Poul Hyttel, Kristine K Freude, Vanessa J Hall
Previous research has shown that a subpopulation of cells within cultured human dermal fibroblasts, termed multilineage-differentiating stress enduring (Muse) cells, are preferentially reprogrammed into induced pluripotent stem cells. However, controversy exists over whether these cells are the only cells capable of being reprogrammed from a heterogeneous population of fibroblasts. Similarly, there is little research to suggest such cells may exist in embryonic tissues or other species. In order to address if such a cell population exists in pigs, we investigated porcine embryonic fibroblast populations (pEFs) and identified heterogeneous expression of several key cell surface markers...
April 20, 2017: Cell Cycle
https://www.readbyqxmd.com/read/28425966/endurance-training-with-or-without-glucose-fructose-ingestion-effects-on-lactate-metabolism-assessed-in-a-randomized-clinical-trial-on-sedentary-men
#12
Robin Rosset, Virgile Lecoultre, Léonie Egli, Jérémy Cros, Valentine Rey, Nathalie Stefanoni, Valérie Sauvinet, Martine Laville, Philippe Schneiter, Luc Tappy
Glucose-fructose ingestion increases glucose and lactate oxidation during exercise. We hypothesized that training with glucose-fructose would induce key adaptations in lactate metabolism. Two groups of eight sedentary males were endurance-trained for three weeks while ingesting either glucose-fructose (GF) or water (C). Effects of glucose-fructose on lactate appearance, oxidation, and clearance were measured at rest and during exercise, pre-training, and post-training. Pre-training, resting lactate appearance was 3...
April 20, 2017: Nutrients
https://www.readbyqxmd.com/read/28425744/once-a-frog-lover-always-a-frog-lover-infants-goal-generalization-is-influenced-by-the-nature-of-accompanying-speech
#13
Alia Martin, Catharyn C Shelton, Jessica A Sommerville
The ability to interpret choices as enduring preferences that generalize beyond the immediate situation gives adults a powerful means of predicting and explaining others' behavior. How do infants come to recognize that current choices can be driven by generalizable preferences? Although infants can encode others' actions in terms of goals (Woodward, 1998), there is evidence that 10-month-olds still fail to generalize goal information presented in one environment to an event sequence occurring in a new environment (Sommerville & Crane, 2009)...
April 20, 2017: Journal of Experimental Psychology. General
https://www.readbyqxmd.com/read/28425239/an-8-week-thoracic-spine-stabilization-exercise-program-improves-postural-back-pain-spine-alignment-postural-sway-and-core-endurance-in-university-students-a-randomized-controlled-study
#14
Şeyda Toprak Çelenay, Derya Özer Kaya
BACKGROUND/AIM: To investigate the effects of an 8-week thoracic stabilization exercise program on back pain, spinal alignment, postural sway, and core endurance in university students. MATERIALS AND METHODS: University students were randomly allocated into exercise (n: 28) and control (n: 25) groups. The exercise program was carried out 3 days a week for 8 weeks. Postural pain, spinal alignment, postural sway, and core endurance were assessed via visual analogue scale, Spinal Mouse, Biodex Balance System, and McGill's trunk muscle endurance tests at the baseline and after 8 weeks of training...
April 18, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28425231/the-relationship-between-physical-fitness-and-falling-risk-and-fear-of-falling-in-community-dwelling-elderly-people-with-different-physical-activity-levels
#15
Mehmet Duray, Arzu Genç
BACKGROUND/AIM: The aim of this research was to determine the effects of physical activity level (PAL) and physical fitness on falling parameters in community-dwelling elderly people. MATERIALS AND METHODS: Seventy-six elderly people were grouped as low PAL group (group 1, n: 38) and high PAL (group 2, n: 38) according to their PAL scores. PAL was measured by the Physical Activity Scale for the Elderly and muscle strength, muscle endurance, aerobic endurance, and flexibility tests were applied; body mass index (BMI) was calculated for physical fitness measurement...
April 18, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28424947/neurodevelopmental-effects-of-antiepileptic-drugs
#16
Marissa Kellogg, Kimford J Meador
Increasing evidence suggests that exposure to certain antiepileptic drugs (AEDs) during critical periods of development may induce transient or long-lasting neurodevelopmental deficits across cognitive, motor and behavioral domains. The developing nervous system may endure prolonged chronic exposure to AEDs during pregnancy (in utero) or during childhood, which can lead to neurodevelopmental defects such as congenital neural tube defects, lower IQ, language deficits, autism and ADHD. To date, valproate is the most widely recognized AED to significantly negatively affect neurodevelopment, and demonstrates greater adverse effects than any other AEDs that have been assessed...
April 19, 2017: Neurochemical Research
https://www.readbyqxmd.com/read/28424359/effects-of-combined-tiotropium-olodaterol-on-inspiratory-capacity-and-exercise-endurance-in-copd
#17
Denis E O'Donnell, Richard Casaburi, Peter Frith, Anne Kirsten, Dorothy De Sousa, Alan Hamilton, Wenqiong Xue, François Maltais
Two replicate, double-blind, 6-week, incomplete-crossover studies (MORACTO 1 and 2) assessed the effects of tiotropium/olodaterol on inspiratory capacity and exercise endurance time in patients with moderate to severe chronic obstructive pulmonary disease.For each patient, four of five treatments were administered once daily for 6 weeks, with a 21-day washout between treatments: tiotropium/olodaterol 2.5/5 µg or 5/5 µg, tiotropium 5 µg, olodaterol 5 µg or placebo, all via the Respimat inhaler...
April 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28422816/why-not-wait-eight-institutions-share-their-experiences-moving-united-states-medical-licensing-examination-step-1-after-core-clinical-clerkships
#18
Michelle Daniel, Amy Fleming, Colleen O'Conner Grochowski, Vicky Harnik, Sibel Klimstra, Gail Morrison, Arnyce Pock, Michael L Schwartz, Sally Santen
The majority of medical students complete the United States Medical Licensing Examination Step 1 after their foundational sciences; however, there are compelling reasons to examine this practice. This article provides the perspectives of eight MD-granting medical schools that have moved Step 1 after the core clerkships, describing their rationale, logistics of the change, outcomes, and lessons learned. The primary reasons these institutions cite for moving Step 1 after clerkships are to foster more enduring and integrated basic science learning connected to clinical care and to better prepare students for the increasingly clinical focus of Step 1...
April 18, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28422813/a-new-approach-in-assessing-core-muscle-endurance-using-ratings-of-perceived-exertion
#19
James D George, Jeffrey R Tolley, Pat R Vehrs, Joel D Reece, M Fatih Akay, Edward D J Cambridge
This study sought to develop regression models to estimate maximal endurance time by using data from four core muscle endurance tests. Eighty healthy university students (age: 22.7 ± 1.9 yr) performed the plank, right side-bridge, left side-bridge, and back extension tests in a random order. Participants were instructed to hold each static position for a maximal endurance time, while maintaining proper form, and then rest for 5 min between tests. A test administrator recorded participants' ratings of perceived exertion (RPE; modified 10-point scale) every 5 s...
April 4, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28422641/supporting-stroke-motor-recovery-through-a-mobile-application-a-pilot-study
#20
Sonia Lawson, Ziying Tang, Jinjuan Feng
Neuroplasticity and motor learning are promoted with repetitive movement, appropriate challenge, and performance feedback. ARMStrokes, a smartphone application, incorporates these qualities to support motor recovery. Engaging exercises are easily accessible for improved compliance. In a multiple-case, mixed-methods pilot study, the potential of this technology for stroke motor recovery was examined. Exercises calibrated to the participant's skill level targeted forearm, elbow, and shoulder motions for a 6-wk protocol...
May 2017: American Journal of Occupational Therapy: Official Publication of the American Occupational Therapy Association
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