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https://www.readbyqxmd.com/read/29334523/not-a-straight-line-patient-s-experiences-of-prostate-cancer-and-their-journey-through-the-healthcare-system
#1
Kristina Schildmeijer, Oscar Frykholm, Åsa Kneck, Mirjam Ekstedt
BACKGROUND: Cancer and its treatment can severely impact quality of life, giving rise to complex needs with respect to follow-up care. To support patient needs and increase efficiency of care with limited resources, the Swedish government has launched national reforms to redesign cancer care pathways. OBJECTIVE: The aim of this study was to explore how prostate cancer patients experience their journey through the healthcare system when their care is provided according to the standardized care pathway, as described in healthcare policy documents...
January 12, 2018: Cancer Nursing
https://www.readbyqxmd.com/read/29333950/willingness-to-pay-for-an-ebola-vaccine-during-the-2014-2016-ebola-outbreak-in-west-africa-results-from-a-u-s-national-sample
#2
Julia E Painter, Michael E von Fricken, Suyane Viana de O Mesquita, Ralph J DiClemente
The 2014-2016 Ebola virus outbreak in West Africa led to advances in the development of vaccines against Ebola. This study examined factors associated with willingness to pay for an Ebola vaccine among a U.S. national sample during the recent Ebola outbreak. From April 30-May 8, 2015, a national survey was conducted using the GfK Group's KnowlegePanel®. Main outcome measures included willingness to pay at least $1; more than $50; and more than $100 for an Ebola vaccine. Analyses were conducted using weighted multivariable logistic regression...
January 15, 2018: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29333923/perception-and-practice-of-hiv-aids-counseling-and-testing-among-secondary-school-adolescents-in-ogun-waterside-local-government-area-ogun-state-southwest-nigeria
#3
Adekunle D Alabi, Olalekan A Oke, Babatunde O Adedokun, Tamramat I Runsewe-Abiodun
A large proportion of Nigerian adolescents are sexually active and the country has one of the highest HIV prevalence among youths globally. This study was done to assess the perception and practice of HIV/AIDS counseling and testing (HCT) among secondary school adolescents in a rural community in Southwest Nigeria. A cross-sectional descriptive study was carried out using multistage sampling method. The results showed that despite high level of HCT awareness, majority of the adolescents (62.9%) had negative attitude toward it...
January 1, 2018: International Quarterly of Community Health Education
https://www.readbyqxmd.com/read/29332310/advances-and-current-challenges-in-calcium-signaling
#4
REVIEW
Jörg Kudla, Dirk Becker, Erwin Grill, Rainer Hedrich, Michael Hippler, Ursula Kummer, Martin Parniske, Tina Romeis, Karin Schumacher
Content I. II. III. IV. V. VI. VII VIII IX X XI ORCID References SUMMARY: Temporally and spatially defined changes in Ca2+ concentration in distinct compartments of cells represent a universal information code in plants. Recently, it has become evident that Ca2+ signals not only govern intracellular regulation but also appear to contribute to long distance or even organismic signal propagation and physiological response regulation. Ca2+ signals are shaped by an intimate interplay of channels and transporters, and during past years important contributing individual components have been identified and characterized...
January 14, 2018: New Phytologist
https://www.readbyqxmd.com/read/29332004/host-agent-vector-environment-measures-for-electronic-cigarette-research-used-in-nih-grants
#5
Mary L Garcia-Cazarin, Rachel J Mandal, Rachel Grana, Kay L Wanke, Helen I Meissner
OBJECTIVE: The purpose of this study is to describe the focus and comprehensiveness of domains measured in e-cigarette research. METHODS: A portfolio analysis of National Institutes of Health grants focusing on e-cigarette research and funded between the fiscal years 2007 and 2015 was conducted. Grant proposals were retrieved using a government database and coded using the Host-Agent-Vector-Environment (HAVE) model as a framework to characterise the measures proposed...
January 13, 2018: Tobacco Control
https://www.readbyqxmd.com/read/29330198/systematic-review-of-drowning-in-india-assessment-of-burden-and-risk
#6
Caroline Lukaszyk, Rebecca Q Ivers, Jagnoor Jagnoor
AIM: To examine the burden and risk factors for fatal and non-fatal drowning in India. METHODS: Relevant literature was identified through a systematic search of 19 electronic databases and 19 national and global, institutional, organisational and government sources of injury data. Search terms used pertained to drowning, injury, trauma, morbidity and mortality in India. RESULTS: A total of 16 research articles and five data sources were included in the review...
January 12, 2018: Injury Prevention: Journal of the International Society for Child and Adolescent Injury Prevention
https://www.readbyqxmd.com/read/29329941/analysis-of-refuse-to-file-policy-for-generic-drug-application-in-taiwan
#7
I-Chen Sun, Churn-Shiouh Gau
Generic drugs are accounted for majority of medicinal products. To reduce the unnecessary review for incomplete dossiers of generic drugs, Taiwanese government launched a refuse-to-file (RTF) procedure since 2017. The present study aimed to examine the outcome of RTF procedure by analyzing application characteristic, RTF rate and deficiencies found in the submitted dossiers. Descriptions of administrative information, chemistry, manufacturing and controls, bioequivalence study, and comparative dissolution testing were presented during the first 6 months after the implementation of RTF policy...
January 9, 2018: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/29326146/prior-authorization-requirements-for-proprotein-convertase-subtilisin-kexin-type-9-inhibitors-across-us-private-and-public-payers
#8
Jalpa A Doshi, Justin T Puckett, Michael S Parmacek, Daniel J Rader
BACKGROUND: Proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9is) are an innovative treatment option for patients with familial hypercholesterolemia or clinical atherosclerotic cardiovascular disease who require further lowering of low-density lipoprotein cholesterol. However, the high costs of these agents have spurred payers to implement utilization management policies to ensure appropriate use. We examined prior authorization (PA) requirements for PCSK9is across private and public US payers...
January 2018: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/29326003/the-efficacy-of-infection-prevention-and-control-committees-in-lesotho-a-qualitative-study
#9
Eltony Mugomeri
BACKGROUND: The implementation of the core components of infection prevention and control (IPC) recommended by the World Health Organization faces severe challenges, particularly in developing countries. Given that hospital IPC committees in these countries are the key implementers of IPC, there is a need to evaluate their effectiveness. This study qualitatively evaluated the effectiveness of IPC committees in the southern African country of Lesotho with the aim of identifying themes for policy discourse on improving IPC practice in the country...
January 9, 2018: American Journal of Infection Control
https://www.readbyqxmd.com/read/29325555/the-readiness-of-hospital-pharmacists-in-kuwait-to-practise-evidence-based-medicine-a-cross-sectional-study
#10
Ali Jasem Buabbas, Fatemah Mohammad Alsaleh, Hamza Mohamad Al-Shawaf, Ali Abdullah, Abdullah Almajran
BACKGROUND: The evolving role of pharmacists in providing pharmaceutical care, as part of the healthcare team, challenges them to acquire up-to-date knowledge of medicines to make the best clinical decisions. The volume of medical literature is on the increase, and it is important to utilise these resources to optimise patients' therapeutic outcomes. This study aimed at assessing the readiness of government hospital pharmacists in practising evidence-based medicine (EBM) in Kuwait in regards to their attitude, knowledge and skills, as well as the perceived barriers and facilitators...
January 11, 2018: BMC Medical Informatics and Decision Making
https://www.readbyqxmd.com/read/29325401/performance-based-financing-to-strengthen-the-health-system-in-benin-challenging-the-mainstream-approach
#11
Elisabeth Paul, Mohamed Lamine Dramé, Jean-Pierre Kashala, Armand Ekambi Ndema, Marcel Kounnou, Julien Codjovi Aïssan, Karel Gyselinck
BACKGROUND: Performance-based financing (PBF) is often proposed as a way to improve health system performance. In Benin, PBF was launched in 2012 through a World Bank-supported project. The Belgian Development Agency (BTC) followed suit through a health system strengthening (HSS) project. This paper analyses and draws lessons from the experience of BTC-supported PBF alternative approach - especially with regards to institutional aspects, the role of demand-side actors, ownership, and cost-effectiveness - and explores the mechanisms at stake so as to better understand how the "PBF package" functions and produces effects...
April 15, 2017: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/29325400/eliminating-healthcare-associated-infections-in-iran-a-qualitative-study-to-explore-stakeholders-views
#12
Atefeh Esfandiari, Hedayat Salari, Arash Rashidian, Hossein Masoumi Asl, Abbas Rahimi Foroushani, Ali Akbari Sari
BACKGROUND: Although preventable, healthcare-associated infections (HAIs) continue to pose huge health and economic burdens on countries worldwide. Some studies have indicated the numerous causes of HAIs, but only a tiny literature exists on the multifaceted measures that can be used to address the problem. This paper presents stakeholders' opinions on measures for controlling HAIs in Iran. METHODS: We used the qualitative research method in studying the phenomenon...
April 15, 2017: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/29325059/aging-in-the-philippines
#13
Adrian N S Badana, Ross Andel
The Philippines is a diverse country that will experience an increase in its aging population in the near future. The aim of this article is to provide an overview of the main issues surrounding population aging, as well as family caregiving and policies that are of concern to older adults in the Philippines. Policymakers and government leaders must plan for the expected growth in the numbers of older adults, which is likely to increase the demand for services and support for elders and their caregiving families...
January 8, 2018: Gerontologist
https://www.readbyqxmd.com/read/29325025/towards-an-understanding-of-resilience-responding-to-health-systems-shocks
#14
Johanna Hanefeld, Susannah Mayhew, Helena Legido-Quigley, Frederick Martineau, Marina Karanikolos, Karl Blanchet, Marco Liverani, Esther Yei Mokuwa, Gillian McKay, Dina Balabanova
The recent outbreak of Ebola Virus Disease (EVD) in West Africa has drawn attention to the role and responsiveness of health systems in the face of shock. It brought into sharp focus the idea that health systems need not only to be stronger but also more 'resilient'. In this article, we argue that responding to shocks is an important aspect of resilience, examining the health system behaviour in the face of four types of contemporary shocks: the financial crisis in Europe from 2008 onwards; climate change disasters; the EVD outbreak in West Africa 2013-16; and the recent refugee and migration crisis in Europe...
January 9, 2018: Health Policy and Planning
https://www.readbyqxmd.com/read/29323862/healthy-food-procurement-and-nutrition-standards-in-public-facilities-evidence-synthesis-and-consensus-policy-recommendations
#15
Kim D Raine, Kayla Atkey, Dana Lee Olstad, Alexa R Ferdinands, Dominique Beaulieu, Susan Buhler, Norm Campbell, Brian Cook, Mary L'Abbé, Ashley Lederer, David Mowat, Joshna Maharaj, Candace Nykiforuk, Jacob Shelley, Jacqueline Street
INTRODUCTION: Unhealthy foods are widely available in public settings across Canada, contributing to diet-related chronic diseases, such as obesity. This is a concern given that public facilities often provide a significant amount of food for consumption by vulnerable groups, including children and seniors. Healthy food procurement policies, which support procuring, distributing, selling, and/or serving healthier foods, have recently emerged as a promising strategy to counter this public health issue by increasing access to healthier foods...
January 2018: Health Promotion and Chronic Disease Prevention in Canada
https://www.readbyqxmd.com/read/29323515/suboptimal-choice-reward-predictive-signals-and-temporal-information
#16
Paul J Cunningham, Timothy A Shahan
Suboptimal choice refers to preference for an alternative offering a low probability of food (suboptimal alternative) over an alternative offering a higher probability of food (optimal alternative). Numerous studies have found that stimuli signaling probabilistic food play a critical role in the development and maintenance of suboptimal choice. However, there is still much debate about how to characterize how these stimuli influence suboptimal choice. There is substantial evidence that the temporal information conveyed by a food-predictive signal governs its function as both a Pavlovian conditioned stimulus and as an instrumental conditioned reinforcer...
January 2018: Journal of Experimental Psychology. Animal Learning and Cognition
https://www.readbyqxmd.com/read/29323371/combining-experimental-and-modelling-approaches-to-study-the-sources-of-reactive-species-induced-in-water-by-the-cost-rf-plasma-jet
#17
Y Gorbanev, C C W Verlackt, S Tinck, E Tuenter, K Foubert, P Cos, A Bogaerts
The vast biomedical potential of cold atmospheric pressure plasmas (CAPs) is governed by the formation of reactive species. These biologically active species are formed upon the interaction of CAPs with the surroundings. In biological milieu, water plays an essential role. The development of biomedical CAPs thus requires understanding of the sources of the reactive species in aqueous media exposed to the plasma. This is especially important in case of the COST RF plasma jet, which is developed as a reference microplasma system...
January 11, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29321162/risk-of-suicide-attempt-in-poststroke-patients-a-population-based-cohort-study
#18
Tomor Harnod, Cheng-Li Lin, Chia-Hung Kao
BACKGROUND: This nationwide population-based cohort study evaluated the risk of and risk factors for suicide attempt in poststroke patients in Taiwan. METHODS AND RESULTS: The poststroke and nonstroke cohorts consisted of 713 690 patients and 1 426 009 controls, respectively. Adults (aged >18 years) who received new stroke diagnoses according to the International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM; codes 430-438) between 2000 and 2011 were included in the poststroke cohort...
January 10, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29321097/towards-a-supportive-policy-and-commissioning-environment-for-chemsex-in-england
#19
Monty Moncrieff
The use of drugs in sexual settings among gay men (colloquially referred to as 'chemsex') was first observed in services supporting gay men in London in the late 2000s. A decade on and it now features as a policy issue in the UK Government's latest Drug Strategy, with several actions to support a health system response. However, reaching this point has been a slow and challenging process and much remains to be done to facilitate an environment in which evidence-based chemsex interventions can be delivered. With a view to informing the development of policies and services in other contexts, this case report examines the initiatives that have driven a response to chemsex and contributed to policy development in England and highlights remaining challenges to effective service provision...
January 11, 2018: Sexual Health
https://www.readbyqxmd.com/read/29320891/the-political-economy-of-the-assessment-of-value-of-new-health-technologies
#20
Jonathan Karnon, Laura Edney, Hossein Afzali
Health technology assessment provides a common framework for evaluating the costs and benefits of new health technologies to inform decisions on the public funding of new pharmaceuticals and other health technologies. In Australia and England, empirical analyses of the opportunity costs of government spending on new health technologies suggest more quality adjusted life years are being forgone than are being gained by a non-trivial proportion of funded health technologies. This essay considers the relevance of available empirical estimates of opportunity costs and explores the relationship between the public funding of health technologies and broader political and economic factors...
January 1, 2018: Journal of Health Services Research & Policy
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