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Healthcare-associated infections

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https://www.readbyqxmd.com/read/29344355/impact-of-an-antifungal-stewardship-intervention-on-optimization-of-candidemia-management
#1
Hana Rac, Jamie L Wagner, S Travis King, Katie E Barber, Kayla R Stover
Background: Candidemia represents a leading cause of healthcare-associated bloodstream infections with significant morbidity and mortality. Previous studies have demonstrated that comprehensive care bundles improve candidemia management but are time-consuming. Objective: To determine the impact of a one-time targeted candidemia intervention on time to initiation of adequate therapy compared to standard of care. Methods: This Institutional Review Board (IRB)-approved, quasi-experiment evaluated a targeted candidemia intervention involving a single phone call to the primary team providing recommendations for care...
January 2018: Therapeutic Advances in Infectious Disease
https://www.readbyqxmd.com/read/29344098/-time-to-clean-a-systematic-review-and-observational-study-on-the-time-required-to-clean-items-of-reusable-communal-patient-care-equipment
#2
David Scott, Hayley Kane, Annette Rankin
Background: Concerns have been raised over poor standards of hospital cleanliness and insufficient time for staff to clean reusable communal patient care equipment. These items may then act as vectors for the transmission of nosocomial pathogens between hospital patients. Aim: To evaluate the impact of cleaning duration on nosocomial infection rates and estimate the time required to clean care equipment in accordance with national specifications (i.e. a 'time to clean')...
November 2017: Journal of Infection Prevention
https://www.readbyqxmd.com/read/29344097/investigating-the-use-of-an-electronic-hand-hygiene-monitoring-and-prompt-device-influence-and-acceptability
#3
Judith Dyson, Maurice Madeo
Introduction: Hand hygiene (HH) prevents the transmission of healthcare-associated infections. Electronic HH monitoring and prompt devices have been developed to overcome problems with monitoring HH and to improve compliance. Devices monitor room entry and exit and soap use through communication between ceiling sensors and badges worn by practitioners and the badges sense alcohol rub. Objectives: To investigate (1) the impact of devices on HH compliance, (2) how devices influence behaviour and (3) the experience and opinions of practitioners on the use devices...
November 2017: Journal of Infection Prevention
https://www.readbyqxmd.com/read/29341882/development-and-evaluation-of-a-website-for-surveillance-of-healthcare-associated-urinary-tract-infections-in-australia
#4
Oyebola Fasugba, Jane Koerner, Noleen Bennett, Simon Burrell, Roland Laguitan, Alex Hoskins, Wendy Beckingham, Brett G Mitchell, Anne Gardner
Phase II of the Surveillance to Reduce Urinary Tract Infections project piloted a website for point prevalence surveys of healthcare-associated (HAUTI) and catheter-associated urinary tract infection in Australian hospitals and aged care homes. This study describes development and evaluation of the website for online data collection. Evaluation findings from 38 data collectors indicated most respondents found website registration and web form use easy (n=22; 58% and n=16; 43%, respectively). The need for improved computer literacy skills and automated data systems were highlighted...
January 13, 2018: Journal of Hospital Infection
https://www.readbyqxmd.com/read/29341844/empiric-antibiotics-for-sepsis
#5
Sara A Buckman, Isaiah R Turnbull, John E Mazuski
BACKGROUND: Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to infection. Early recognition and treatment are the cornerstones of management. METHODS: Review of the English-language literature. RESULTS: For both sepsis and septic shock "antimicrobials [should be] be initiated as soon as possible and within one hour" (Surviving Sepsis Campaign). The risk of progression from severe sepsis to septic shock increases 8% for each hour before antibiotics are started...
January 17, 2018: Surgical Infections
https://www.readbyqxmd.com/read/29341239/interaction-between-healthcare-professionals-and-parents-is-a-key-determinant-of-parental-distress-during-childhood-hospitalisation-for-respiratory-syncytial-virus-infection-european-rsv-outcomes-study-eros
#6
Xavier Carbonell-Estrany, Alberto Dall'Agnola, John R Fullarton, Barry S Rodgers-Gray, Elisa Girardi, Alessandro Mussa, Natalia Paniagua, Marta Pieretto, Rosa Rodríguez-Fernandez, Paolo Manzoni
AIM: We characterised the distress that parents experienced when their child was hospitalised for respiratory syncytial virus (RSV) infection. METHODS: This survey-based, observational study was conducted during 2014-2015. Meetings were held in Spain and Italy, with 24 parents of RSV hospitalised infants and 11 healthcare professionals experienced in RSV, which identified 110 factors related to parental distress. The resulting questionnaire was completed by another 105 Spanish and Italian parents and 56 healthcare professionals, to assess the impact these factors had on parental distress, using a scale from 0-10 (very unimportant to very important)...
January 17, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29340898/epidemiological-aspects-of-healthcare-associated-infections-and-microbial-genomics
#7
C Mirande, I Bizine, A Giannetti, N Picot, A van Belkum
Hospital-acquired infections (HAIs) are a cause of continuously increasing morbidity and mortality. Most of these infections are caused by a limited set of bacterial species, which share the capability to efficiently spread from patient to patient and to easily acquire antibiotic resistance determinants. This renders correct and rapid species identification and antibiotic susceptibility testing (AST) important and underscores the relevance of bacterial epidemiological typing. The latter is needed for the sensitive detection and exact tracing of nosocomial spread of these potentially multidrug-resistant microorganisms (MDRO)...
January 17, 2018: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/29340463/prevalence-of-and-risk-factors-associated-with-the-presence-of-staphylococcus-aureus-in-the-chronic-wounds-of-patients-treated-in-primary-health-care-settings-in-brazil
#8
Eliane Patricia Lino Pereira-Franchi, Maria Rachel Nogueira Barreira, Natália de Sousa Lima Moreira da Costa, Carlos Magno Castelo Branco Fortaleza, Maria de Lourdes Ribeiro de Souza da Cunha
INTRODUCTION: Wounds can be colonized by methicillin-resistant Staphylococcus aureus (MRSA). METHODS: We evaluated the prevalence of S. aureus and MRSA in the wounds of patients treated at Basic Health Units in Brazil and identified risk factors associated with their presence. RESULTS: The prevalence rates of S. aureus and MRSA were 51.5% and 8.7%, respectively. There was a correlation between the presence of S. aureus in wounds and nostrils (p<0...
November 2017: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/29340451/is-waste-collection-associated-with-hepatitis-b-infection-a-meta-analysis
#9
Marcos Paulo Gomes Mol, Sandy Cairncross, Dirceu Bartolomeu Greco, Leo Heller
This meta-analysis, which is based on a previously published systematic review, aims to contribute to the scientific discussion on hepatitis B virus (HBV) infection in workers who are exposed to domestic and healthcare wastes. Publications were sought which had been made available on the data used by December 2013 and updated to December 2016. The quality of the included studies was assessed according to the guidelines of Loney et al. for the critical appraisal of studies on the prevalence or incidence of a health problem...
November 2017: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/29339200/preventing-healthcare-associated-gram-negative-bloodstream-infections
#10
EDITORIAL
James Gray, Beryl Oppenheim, Nikunj Mahida
No abstract text is available yet for this article.
January 12, 2018: Journal of Hospital Infection
https://www.readbyqxmd.com/read/29336929/economic-burden-and-cost-effective-management-of-clostridium-difficile-infections
#11
REVIEW
S M Heimann, M R Cruz Aguilar, S Mellinghof, M J G T Vehreschild
Clostridium difficile infection (CDI) is the most important cause of healthcare-associated infectious diarrhea in industrialized countries. We performed a literature review of the overall economic burden of initial and recurrent CDI as well as of the cost-effectiveness of the various treatment strategies applied in these settings. Even though analysis of health economic data is complicated by the limited comparability of results, our review identified several internationally consistent results. Authors from different countries have shown that recurrent CDI disproportionally contributes to the overall economic burden of CDI and therefore offers considerable saving potential...
January 11, 2018: Médecine et Maladies Infectieuses
https://www.readbyqxmd.com/read/29335343/association-between-glucocorticoid-exposure-and-healthcare-expenditures-for-potential-glucocorticoid-related-adverse-events-in-patients-with-rheumatoid-arthritis
#12
Jennie H Best, Amanda M Kong, Gregory M Lenhart, Khaled Sarsour, Marni Stott-Miller, Yong Hwang
OBJECTIVE: Oral glucocorticoid (OGC) use for rheumatoid arthritis (RA) is debated because of the adverse event (AE) profile of OGC. We evaluated the associations between cumulative doses of OGC and potential OGC-related AE, and quantified the associated healthcare expenditures. METHODS: Using the MarketScan databases, patients ≥ 18 years old who have RA with continuous enrollment from January 1 to December 31, 2012 (baseline), and from January 1 to December 31, 2013 (evaluation period), were identified...
January 15, 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29334886/factors-associated-with-recent-unsuppressed-viral-load-in-hiv-1-infected-patients-in-care-on-first-line-antiretroviral-therapy-in-south-africa
#13
D Joseph Davey, Z Abrahams, M Feinberg, M Prins, C Serrao, B Medeossi, E Darkoh
Unsuppressed viral load (VL) in patients on antiretroviral therapy (ART) occurs when treatment fails to suppress a person's VL and is associated with decreased survival and increased HIV transmission. The objective of this study was to evaluate factors associated with unsuppressed VL (VL > 400 copies/ml) in patients currently in care on first-line ART for ≥ 6 months attending South African public healthcare facilities. We analysed electronic medical records of ART patients with a VL result on record who started ART between January 2004 and April 2016 from 271 public health facilities...
January 1, 2018: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/29331160/reduction-in-rate-of-nosocomial-respiratory-virus-infections-in-a-children-s-hospital-associated-with-enhanced-isolation-precautions
#14
Lorry G Rubin, Nina Kohn, Susan Nullet, Margaret Hill
OBJECTIVE To determine whether the use of enhanced isolation precautions (droplet and contact precautions) for inpatients with respiratory tract viral infections is associated with a reduction in rate of nosocomial viral respiratory infections. DESIGN Quasi-experimental study with the rate of nosocomial respiratory virus infection as the primary dependent variable and rate of nosocomial Clostridium difficile infection as a nonequivalent dependent variable comparator. SETTING Cohen Children's Medical Center of NY, a tertiary-care children's hospital attached to a large general hospital...
January 14, 2018: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/29331159/diagnostic-stewardship-for-healthcare-associated-infections-opportunities-and-challenges-to-safely-reduce-test-use
#15
Gregory R Madden, Robert A Weinstein, Costi D Sifri
No abstract text is available yet for this article.
January 14, 2018: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/29330346/underestimation-of-staphylococcus-aureus-mrsa-and-mssa-carriage-associated-with-standard-culturing-techniques-one-third-of-carriers-missed
#16
S T J Tsang, M P McHugh, D Guerendiain, P J Gwynne, J Boyd, A H R W Simpson, T S Walsh, I F Laurenson, K E Templeton
OBJECTIVES: Nasal carriers of Staphylococcus (S.) aureus (MRSA and MSSA) have an increased risk for healthcare-associated infections. There are currently limited national screening policies for the detection of S. aureus despite the World Health Organization's recommendations. This study aimed to evaluate the diagnostic performance of molecular and culture techniques in S. aureus screening, determine the cause of any discrepancy between the diagnostic techniques, and model the potential effect of different diagnostic techniques on S...
January 2018: Bone & Joint Research
https://www.readbyqxmd.com/read/29329916/impact-of-the-international-nosocomial-infection-control-consortium-s-multidimensional-approach-on-rates-of-ventilator-associated-pneumonia-in-14-intensive-care-units-in-11-hospitals-of-5-cities-within-argentina
#17
Victor Daniel Rosenthal, Javier Desse, Diego Marcelo Maurizi, Gustavo Jorge Chaparro, Pablo Wenceslao Orellano, Viviana Chediack, Rafael Cabrera, Daniel Golschmid, Cristina Graciela Silva, Julio Cesar Vimercati, Juan Pablo Stagnaro, Ivanna Perez, María Laura Spadaro, Adriana Miriam Montanini, Dina Pedersen, Teresa Laura Paniccia, Ana María Ríos Aguilera, Raul Cermesoni, Juan Ignacio Mele, Ernesto Alda, Analía Edith Paldoro, Agustín Román Ortta, Bettina Cooke, María Cecilia García, Mora Nair Obed, Cecilia Verónica Domínguez, Pablo Alejandro Saúl, María Cecilia Rodríguez Del Valle, Alberto Claudio Bianchi, Gustavo Alvarez, Ricardo Pérez, Carolina Oyola
BACKGROUND: To analyze the impact of the International Nosocomial Infection Control Consortium (INICC) multidimensional approach (IMA) on ventilator-associated pneumonia (VAP) rates in 11 hospitals within 5 cities of Argentina from January 2014-April 2017. METHODS: A multicenter, prospective, before-after surveillance study was conducted through the use of International Nosocomial Infection Control Consortium Surveillance Online System. During baseline, we performed outcome surveillance of VAP applying the definitions of the Centers for Disease Control andPrevention's National Healthcare Safety Network...
January 9, 2018: American Journal of Infection Control
https://www.readbyqxmd.com/read/29329528/transmission-of-measles-among-healthcare-workers-in-hospital-w-xinjiang-autonomous-region-china-2016
#18
Haimei Jia, Chao Ma, Mengting Lu, Jianping Fu, Lance E Rodewald, Qiru Su, Huaqin Wang, Lixin Hao
BACKGROUND: As China approaches the elimination of measles, outbreaks of measles continue to occur. Healthcare workers (HCWs) are known to be at high risk of infection and transmission of measles virus. A measles outbreak occurred in a hospital in Xinjiang Uighur Autonomous Region of the People's Republic of China. We report an investigation of this outbreak and its implications for measles elimination and outbreak preparedness. METHODS: We conducted a retrospective search for measles cases using hospital records...
January 12, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29327419/treatment-interruption-in-hiv-positive-patients-followed-up-in-cameroon-s-antiretroviral-treatment-program-individual-and-healthcare-supply-related-factors-anrs-12288-evolcam-survey
#19
Christelle Tong, Marie Suzan-Monti, Luis Sagaon-Teyssier, Mohamed Mimi, Christian Laurent, Gwenaëlle Maradan, Marie-Thérèse Mengue, Bruno Spire, Christopher Kuaban, Laurent Vidal, Sylvie Boyer
INTRODUCTION: Decreasing international financial resources for HIV and increasing numbers of antiretroviral treatment (ART) treated patients may jeopardize treatment continuity in low income settings. Using data from the EVOLCam ANRS-12288 survey, this study aimed to document the prevalence of unplanned treatment interruption for more than 2 consecutive days (TI>2d) and investigate associated individual and healthcare supply-related factors within the Cameroonian ART Program. METHODS: A cross-sectional mixed methods survey was carried out between April and December 2014 in 19 HIV services of the Center and Littoral regions...
January 12, 2018: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/29327237/regional-age-and-respiratory-secretion-specific-prevalence-of-respiratory-viruses-associated-with-asthma-exacerbation-a-literature-review
#20
REVIEW
Xue-Yan Zheng, Yan-Jun Xu, Wei-Jie Guan, Li-Feng Lin
Despite increased understanding of how viral infection is involved in asthma exacerbations, it is less clear which viruses are involved and to what extent they contribute to asthma exacerbations. Here, we sought to determine the prevalence of different respiratory viruses during asthma exacerbations. Systematic computerized searches of the literature up to June 2017 without language limitation were performed. The primary focus was on the prevalence of respiratory viruses, including AdV (adenovirus), BoV (bocavirus), CoV (coronavirus), CMV (cytomegalovirus), EnV (enterovirus), HSV (herpes simplex virus), IfV (influenza virus), MpV (metapneumovirus), PiV (parainfluenzavirus), RV (rhinovirus) and RSV (respiratory syncytial virus) during asthma exacerbations...
January 11, 2018: Archives of Virology
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