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Diet ulcerative colitis

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https://www.readbyqxmd.com/read/27863347/preventive-effects-of-goji-berry-on-dextran-sulfate-sodium-induced-colitis-in-mice
#1
Yifei Kang, Yansong Xue, Min Du, Mei-Jun Zhu
Goji berry (Lycium barbarum) exerts immune modulation and suppresses inflammation in vitro and in vivo. We hypothesized that Goji berry had beneficial effects on dextran sulfate sodium (DSS)-induced colitis in C57BL/6 mice through suppressing inflammation. Six-week-old male C57BL/6 mice were supplemented with a standard AIN-93G diet with or without 1% (w/w) Goji berry for 4 weeks. Then, colitis was induced by supplementing 3% DSS in drinking water for 7 days, followed by 7 days of remission period to mimic ulcerative colitis symptoms...
October 27, 2016: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/27812084/nutrition-oxidative-stress-and-intestinal-dysbiosis-influence-of-diet-on-gut-microbiota-in-inflammatory-bowel-diseases
#2
Giovanni Tomasello, Margherita Mazzola, Angelo Leone, Emanuele Sinagra, Giovanni Zummo, Felicia Farina, Provvidenza Damiani, Francesco Cappello, Alice Gerges Geagea, Abdo Jurjus, Tarek Bou Assi, Massimiliano Messina, Francesco Carini
BACKGROUND: Microbiota refers to the population of microorganisms (bacteria, viruses and fungi) that inhabit the entire gastrointestinal tract, more particularly the colon whose role is to maintain the integrity of the intestinal mucosa and control the proliferation of pathogenic bacteria. Alteration in the composition of the gut microbiota is called dysbiosis. Dysbiosis redisposes to inflammatory bowel diseases such as ulcerative colitis, Crohn disease and indeterminate colitis. METHODS: The purpose of this literature review is to elucidate the influence of diet on the composition of the gastrointestinal microbiota in the healthy gut and the role of diet in the development of dysbiosis...
October 26, 2016: Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia
https://www.readbyqxmd.com/read/27768566/development-and-application-of-a-plant-based-diet-scoring-system-for-japanese-patients-with-inflammatory-bowel-disease
#3
Mitsuro Chiba, Kunio Nakane, Yuko Takayama, Kae Sugawara, Hideo Ohno, Hajime Ishii, Satoko Tsuda, Tsuyotoshi Tsuji, Masafumi Komatsu, Takeshi Sugawara
CONTEXT: Plant-based diets (PBDs) are a healthy alternative to westernized diets. A semivegetarian diet, a PBD, has been shown to prevent a relapse in Crohn disease. However, there is no way to measure adherence to PBDs. OBJECTIVE: To develop a simple way of evaluating adherence to a PBD for Japanese patients with inflammatory bowel disease (IBD). DESIGN: PBD scores were assigned according to the frequency of consumption provided on a food-frequency questionnaire, obtained on hospitalization for 159 patients with ulcerative colitis and 70 patients with Crohn disease...
2016: Permanente Journal
https://www.readbyqxmd.com/read/27750262/the-obestatin-ghrelin-ratio-and-ghrelin-genetics-in-adult-celiac-patients-before-and-after-a-gluten-free-diet-in-irritable-bowel-syndrome-patients-and-healthy-individuals
#4
Francesco Russo, Guglielmina Chimienti, Michele Linsalata, Caterina Clemente, Antonella Orlando, Giuseppe Riezzo
BACKGROUND: Ghrelin levels and obestatin/ghrelin ratio have been proposed as activity markers in ulcerative colitis, but no data are available in celiac disease (CD) and irritable bowel syndrome (IBS). Our aims were as follows: (a) to assess obestatin and ghrelin concentrations in adult active CD patients, diarrhea-predominant IBS (IBS-d), and healthy controls (HC) in relation to intestinal permeability; (b) to evaluate the ghrelin-obestatin profile in CD patients after a 1-year gluten-free diet (GFD); and (c) to establish the impact of ghrelin genetics...
October 12, 2016: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/27743467/therapeutic-modulation-of-the-gut-microbiota-in-ibd-more-questions-to-be-answered
#5
Yu Qi Qiao, Chen Wen Cai, Zhi Hua Ran
Inflammatory bowel disease (IBD) patients exhibit impaired control of the microbiome in the gut. "Dysbiosis" is commonly observed. A Western diet is a risk factor for the development of IBD but may have different effects on the gut microbiota in IBD and non-IBD individuals. Exclusive enteral nutrition (EEN) can induce remission in pediatric Crohn's disease (CD) with a decrease in gut microbiome diversity after EEN treatment. Although there are some theoretical benefits, the actual treatment effects of prebiotics and probiotics in IBD patients can vary...
October 15, 2016: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/27706028/lycopene-lutein-and-zeaxanthin-may-reduce-faecal-blood-mucus-and-pus-but-not-abdominal-pain-in-individuals-with-ulcerative-colitis
#6
Dominika Głąbska, Dominika Guzek, Paulina Zakrzewska, Dariusz Włodarek, Gustaw Lech
BACKGROUND: The main symptom of ulcerative colitis is diarrhoea, which is often accompanied by painful tenesmus and faecal blood and mucus. It sometimes co-occurs with abdominal pain, fever, feeling of fatigue, loss of appetite and weight loss. Some dietary factors have been indicated as important in the treatment of ulcerative colitis. The aim of the study was to analyse the association between retinoid intake (total vitamin A, retinol, β-carotene, α-carotene, β-cryptoxanthin, lycopene, lutein and zeaxanthin) and ulcerative colitis symptoms (abdominal pain, faecal blood, faecal mucus, faecal pus) in individuals with ulcerative colitis in remission...
September 30, 2016: Nutrients
https://www.readbyqxmd.com/read/27704622/the-human-gastrointestinal-tract-and-oral-microbiota-in-inflammatory-bowel-disease-a-state-of-the-science-review
#7
Rosario Lucas López, María José Grande Burgos, Antonio Gálvez, Rubén Pérez Pulido
Inflammatory bowel disease (IBD) includes a spectrum of diseases from ulcerative colitis (UC) to Crohn's disease (CD). Many studies have addressed the changes in the microbiota of individuals affected by UC and CD. A decrease in biodiversity and depletion of the phyla Bacteroidetes and Firmicutes has been reported, among others. Changes in microbial composition also result in changes in the metabolites generated in the gut from microbial activity that may involve the amount of butyrate and other metabolites such as H2 S being produced...
October 5, 2016: APMIS: Acta Pathologica, Microbiologica, et Immunologica Scandinavica
https://www.readbyqxmd.com/read/27681914/microbiome-metabolome-and-inflammatory-bowel-disease
#8
REVIEW
Ishfaq Ahmed, Badal C Roy, Salman A Khan, Seth Septer, Shahid Umar
Inflammatory Bowel Disease (IBD) is a multifactorial disorder that conceptually occurs as a result of altered immune responses to commensal and/or pathogenic gut microbes in individuals most susceptible to the disease. During Crohn's Disease (CD) or Ulcerative Colitis (UC), two components of the human IBD, distinct stages define the disease onset, severity, progression and remission. Epigenetic, environmental (microbiome, metabolome) and nutritional factors are important in IBD pathogenesis. While the dysbiotic microbiota has been proposed to play a role in disease pathogenesis, the data on IBD and diet are still less convincing...
June 15, 2016: Microorganisms
https://www.readbyqxmd.com/read/27638834/patients-perceive-clinical-benefit-with-the-specific-carbohydrate-diet-for-inflammatory-bowel-disease
#9
David L Suskind, Ghassan Wahbeh, Stanley A Cohen, Christopher J Damman, Jani Klein, Kim Braly, Michele Shaffer, Dale Lee
BACKGROUND: Recent studies suggest that dietary therapy may be effective for patients with inflammatory bowel disease (IBD), but limited published data exist on the usage and efficacy of dietary therapy. AIM: To evaluate the perspective of IBD patients using the specific carbohydrate diet (SCD). METHODS: An anonymous online survey was conducted using REDCap, a Web-based survey tool. Survey links were sent to known Web sites as well as support groups in an attempt to characterize patient utilization of the SCD and perception of efficacy of the SCD...
November 2016: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/27588050/therapeutic-effects-of-triptolide-via-the-inhibition-of-il-1%C3%AE-expression-in-a-mouse-model-of-ulcerative-colitis
#10
Haifeng Zhang, Chen Gong, Lishuai Qu, Xiaoling Ding, Wei Cao, Haiqin Chen, Bin Zhang, Guoxiong Zhou
The present study aimed to investigate the effect of triptolide (TL) on ulcerative colitis (UC) and explore the potential association between the therapeutic effects of TL and IL-1β expression using a 4,4-dimethyl-4-silapentane-1-sulfonic acid (DSS)-induced mouse model to simulate human UC. A total of 70 BALB/c female mice were randomly allocated into seven equal groups: Group A, blank control; group B, normal saline injection; group C, propylene glycol injection; group D (TL1), 0.2 mg/kg TL; group E (TL2), 0...
September 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/27585552/in%C3%A2-vitro-analysis-of-partially-hydrolyzed-guar-gum-fermentation-on-identified-gut-microbiota
#11
Justin Carlson, Trevor Gould, Joanne Slavin
BACKGROUND: Prebiotic dietary fibers resist digestion in the upper gastrointestinal tract and allow for stimulation of bacteria in the distal intestine and colon. Stimulation of bacteria among different individuals varies greatly, depending on a wide range of variables. OBJECTIVE: To determine the range of differences in response between individuals, a preclinical in vitro fermentation was conducted with six fecal donors. The primary objective was to compare the fecal microbiota of six individuals at baseline, 12 h and 24 h post-exposure to partially hydrolyzed guar gum (PHGG)...
August 30, 2016: Anaerobe
https://www.readbyqxmd.com/read/27548430/the-search-for-causative-environmental-factors-in-inflammatory-bowel-disease
#12
Gerhard Rogler, Jonas Zeitz, Luc Biedermann
Inflammatory bowel disease (IBD) has become a 'prototype disease' for chronic auto-inflammatory disorders with a polygenic background and important multifaceted environmental trigger components. The environmental factors contribute both to pathogenesis and disease flares. Thus, IBD is a disease par excellence to study the interactions between host genetics, environmental factors (such as infections or smoking) and 'in-vironmental' factors - for example, our intestinal microbiota. Longitudinal intercurrent events, including the impact of long-term medication on disease progression or stabilization, can exemplarily be studied in this disease group...
2016: Digestive Diseases
https://www.readbyqxmd.com/read/27478535/bioactivity-of-polyphenols-preventive-and-adjuvant-strategies-toward-reducing-inflammatory-bowel-diseases-promises-perspectives-and-pitfalls
#13
REVIEW
Anouk Kaulmann, Torsten Bohn
Inflammatory bowel diseases (IBDs) are characterized by autoimmune and inflammation-related complications of the large intestine (ulcerative colitis) and additional parts of the digestive tract (Crohn's disease). Complications include pain, diarrhoea, chronic inflammation, and cancer. IBD prevalence has increased during the past decades, especially in Westernized countries, being as high as 1%. As prognosis is poor and medication often ineffective or causing side effects, additional preventive/adjuvant strategies are sought...
2016: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/27474198/patient-satisfaction-in-the-management-of-mild-to-moderate-ulcerative-colitis-results-of-a-delphi-study-among-patients-and-physicians
#14
Francesc Casellas, Daniel Ginard, Sabino Riestra
GOALS: To determine factors contributing to satisfaction with treatment in mild-to-moderate ulcerative colitis (UC) from both the patients and the physicians perspectives. BACKGROUND: Despite the impact of UC on different aspects of daily life, patient's and physician's satisfaction with clinical management has been poorly evaluated. STUDY: A Delphi study involving 22 patients and 20 clinicians was conducted. The patient's questionnaire included 285 items regarding diagnosis, treatment, and follow-up, whereas the physician's questionnaire added 32 specific items for clinicians...
October 2016: Digestive and Liver Disease
https://www.readbyqxmd.com/read/27459113/preventive-and-curative-effect-of-pistacia-lentiscus-oil-in-experimental-colitis
#15
Mustafa S Naouar, Lilia Zouiten Mekki, Lamia Charfi, Jalel Boubaker, Azza Filali
AIM: to investigate the anti-inflammatory effect of the Pistacia lentiscus oil in experimental colitis model. MATERIALS AND METHODS: Colitis was induced in male rats by instillation of 2,4,6-trinitrobenzenesulfonic acid (TNBS) in all groups. The experimental groups consisted of: 5 rats received Lentisc oil 2months before colitis induction (preventive group), 5 rats received the oil on the day of colitis induction (curative group) and 5 control rats. Lentisc oil was extracted from the ripe fruit of the plant by the cold press method and was analyzed by spectro-chromatography...
July 23, 2016: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/27440687/food-intolerance-prevalence-in-active-ulcerative-colitis-in-southwest-china
#16
Xinling Ma, Yuke Chen, Fangyan Huang, Qianying Luo, Hui Lv, Hua Long
BACKGROUND AND OBJECTIVES: Food intolerance is believed to be a source of frequent medical problems in ulcerative colitis (UC), which closely correlate with patients' dietary pattern. Living in an underdeveloped area of China, residents in southwestern region have diverse dietary habits. The objective of this study is to determine the prevalence of food intolerance in the UC patients in this area and to discuss some of the possible risk factors leading to the condition. METHODS AND STUDY DESIGN: Food antibodies in serum of 80 patients with active UC were determined by standard enzyme-linked immuno sorbent assay (ELISA)...
2016: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27338852/prevalence-and-associated-factors-of-abnormal-liver-values-in-children-with-celiac-disease
#17
Linnea Äärelä, Samuli Nurminen, Laura Kivelä, Heini Huhtala, Markku Mäki, Anna Viitasalo, Katri Kaukinen, Timo Lakka, Kalle Kurppa
BACKGROUND: The prevalence and factors associated with transaminasemia in celiac disease are poorly known. AIMS: To investigate these issues in paediatric celiac patients and controls. METHODS: Alanine aminotransferase (ALT) was studied in 150 children with untreated celiac disease, 161 disease controls and 500 population-based controls. The association between ALT and clinical and histological variables and the effect of a gluten-free diet were investigated in celiac patients...
September 2016: Digestive and Liver Disease
https://www.readbyqxmd.com/read/27311821/mouse-models-of-intestinal-inflammation-and-cancer
#18
REVIEW
Aya M Westbrook, Akos Szakmary, Robert H Schiestl
Chronic inflammation is strongly associated with approximately one-fifth of all human cancers. Arising from combinations of factors such as environmental exposures, diet, inherited gene polymorphisms, infections, or from dysfunctions of the immune response, chronic inflammation begins as an attempt of the body to remove injurious stimuli; however, over time, this results in continuous tissue destruction and promotion and maintenance of carcinogenesis. Here, we focus on intestinal inflammation and its associated cancers, a group of diseases on the rise and affecting millions of people worldwide...
September 2016: Archives of Toxicology
https://www.readbyqxmd.com/read/27282271/coordinated-hospital-home-fecal-microbiota-transplantation-via-percutaneous-endoscopic-cecostomy-for-recurrent-steroid-dependent-ulcerative-colitis
#19
Xiaodong Ni, Shengxian Fan, Yongliang Zhang, Zhiming Wang, Lan Ding, Yousheng Li, Jieshou Li
Since its introduction as an alternative intestinal microbiota alteration approach, fecal microbiota transplantation (FMT) has been increasingly used as a treatment of choice for patients with ulcerative colitis (UC), but no reports exist regarding FMT via percutaneous endoscopic cecostomy (PEC). This report describes the case of a 24-year-old man with a 7-year history of recurrent, steroid-dependent UC. He received FMT via PEC once per day for 1 month in the hospital. After the remission of gastrointestinal symptoms, he was discharged from the hospital and continued FMT via PEC twice per week for 3 months at home...
June 13, 2016: Gut and Liver
https://www.readbyqxmd.com/read/27269901/report-impact-of-inflammatory-bowel-disease
#20
Sheila M Wilhelm
Inflammatory bowel disease (IBD) includes ulcerative colitis (UC) and Crohn's disease (CD), 2 conditions characterized by chronic inflammation. Approximately 1.17 million people in the United States are affected by these 2 conditions. It is theorized that a genetic susceptibility coupled with environmental factors, such as smoking, antibiotics, oral contraceptives, appendectomy, or diet, may influence the development of IBD. Patients with UC and CD may exhibit similar symptoms, and the conditions are often misclassified, as there is a lack of standard criteria for diagnosing IBD...
March 2016: American Journal of Managed Care
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