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Lymphoscintigraphy

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https://www.readbyqxmd.com/read/28931417/sentinel-lymph-node-biopsy-in-periocular-merkel-cell-carcinoma-a-case-report
#1
Dan C Filitis, Gyorgy Paragh, Faramarz H Samie, Nathalie C Zeitouni
BACKGROUND: The National Comprehensive Cancer Network guidelines for Merkel cell carcinoma recommend performance of the sentinel lymph node biopsy in all patients with clinically negative nodal disease for staging and treatment. Nevertheless, sentinel lymph node biopsy in the periocular region is debated as tumors are typically smaller and lymphatic variability can make performance procedurally problematic. CASE PRESENTATION: We present a case of a Caucasian patient in their seventies who presented with a 1...
September 20, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28913301/concordant-surgical-treatment-non-melanocytic-skin-cancer-of-the-head-and-neck
#2
Wan Cheol Ryu, In Chang Koh, Yong Hae Lee, Jong Hyun Cha, Sang Il Kim, Chang Gyun Kim
BACKGROUND: Skin cancer is the most common type of cancer. Of the 4 million skin lesions excised annually worldwide, approximately 2 million are considered cancerous. In this study, we aimed to describe a regional experience with skin cancers treated by a single senior surgeon and to provide a treatment algorithm. METHODS: The medical records of 176 patients with head and neck non-melanocytic skin cancer (NMSC) who were treated by a single surgeon at our institution between January 2010 and May 2016 were retrospectively reviewed, and their data (age, sex, pathological type, tumor location/size, treatment modality) were analyzed...
March 2017: Arch Craniofac Surg
https://www.readbyqxmd.com/read/28875761/an-ultralow-dose-1-day-protocol-with-activities-lower-than-20-mbq-for-the-detection-of-sentinel-lymph-nodes-in-breast-cancer-experiences-after-150-cases
#3
Hans-Christian Kolberg, Shabnam Afsah, Thorsten Kuehn, Ute Winzer, Leyla Akpolat-Basci, Miltiades Stephanou, Sarah Wetzig, Oliver Hoffmann, Cornelia Liedtke
INTRODUCTION: Common protocols for the detection of sentinel lymph nodes in early breast cancer often include the injection of the tracer 1 day before surgery. In order to detect enough activity on the day of surgery, the applied activity in many protocols is as high as several hundred MBq. So far, very few protocols with an activity below 20 MBq have been reported. We developed an ultralow-dose 1-day protocol with a mean activity lower than 20 MBq in order to reduce radiation exposure for patients and staff...
January 1, 2017: Technology in Cancer Research & Treatment
https://www.readbyqxmd.com/read/28875122/the-utility-of-sentinel-node-biopsy-for-sinonasal-melanoma
#4
Michael S Oldenburg, Daniel L Price
Objective  Report two positive sentinel node biopsies for sinonasal melanoma. Design  Retrospective review. Setting  Academic tertiary care center. Participants  Patients who underwent sentinel node biopsy for sinonasal melanoma between November 1, 2014 and November 1, 2015. Main Outcome Measures  Clinical course. Results  Two patients were identified. Patient 1 (83M) presented with a sinonasal melanoma anterior to the left inferior turbinate and was clinically N0 neck. Lymphoscintigraphy revealed two sentinel nodes in the ipsilateral and three in the contralateral cervical basins...
October 2017: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/28874624/feasibility-of-lymphoscintigraphy-for-sentinel-node-identification-after-neo-adjuvant-therapy
#5
Giovanni Corso, Chiara Maria Grana, Laura Gilardi, Silvia Melania Baio, Daniela De Lorenzo, Patrick Maisonneuve, Nicole Rotmensz, Bettina Ballardini, Germana Lissidini, Silvia Ratini, Fabio D Bassi, Paolo Veronesi, Viviana Galimberti
AIM: To assess the sentinel-node identification rate at lymphoscintigraphy and its technical feasibility after neo-adjuvant treatments. MATERIAL OF STUDY: Between 2000 and 2013, 444 consecutive patients affected by primary locally advanced breast cancer were enrolled in this study. All individuals were candidate for neo-adjuvant treatments and for lymphoscintigraphy before surgery. RESULTS: The median age was 44 years at onset; almost one sentinel node was identified during lymphoscintigraphy in 430 cases...
2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/28861856/role-of-sentinel-node-in-differentiated-thyroid-cancer-a-prospective-study-comparing-patent-blue-injection-technique-lymphoscintigraphy-and-the-combined-technique
#6
R Gelmini, M Campanelli, F Cabry, A Franceschetto, G Ceresini, L Ruffini, A Zaccaroni, P Del Rio
PURPOSE: The purpose of the present study was to evaluate the feasibility and reproducibility of the sentinel lymph node (SLNs) biopsy in differentiated thyroid cancer using patent blue injection, lymphoscintigraphy and the combined techniques. METHODS: Between January 2011 and January 2013, 82 consecutive patients were enrolled in our prospective multicentre study. Inclusion criteria were 18 years of age, preoperative diagnosis of differentiated thyroid carcinoma, no evidence of lymph node enlargement and multifocal neoplasm...
August 31, 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/28856118/prognostic-value-of-multiple-draining-lymph-node-basins-in-melanoma-a-matched-pair-analysis-based-on-the-john-wayne-cancer-institute-experience
#7
J Harrison Howard, Junko J Ozao-Choy, Jason M Hiles, Myung-Shin Sim, Mark B Faries
BACKGROUND: The prognostic significance of multiple draining basins is controversial in melanoma because analyses have not adequately controlled for standard prognostic variables. We hypothesized that an analysis based on prognostically matched pairs of patients with multiple versus single drainage basins would clarify any independent role of basin number. STUDY DESIGN: We identified patients in our 40-year prospective database, who underwent preoperative lymphoscintigraphy, intraoperative sentinel node biopsy and wide local excision for cutaneous melanoma...
2017: Frontiers in Oncology
https://www.readbyqxmd.com/read/28852879/using-fluorescence-lymphangiography-to-define-the-ileocolic-mesentery-proof-of-concept-for-the-watershed-area-using-real-time-imaging
#8
D S Keller, H M Joshi, M Rodriguez-Justo, D Walsh, J C Coffey, M Chand
Recent advances in mesenteric science have demonstrated that the mesentery is a continuous structure with a 'watershed' area at the mesenteric apex between the right colon and terminal ileum, where lymphatic flow can proceed either proximally or distally. With this new understanding of the anatomy, functional features are emerging, which can have an impact on surgical management. Fluorescence lymphangiography or lymphoscintigraphy with indocyanine green allows real-time visualization of lymphatic channels, which highlights sentinel lymph nodes and may facilitate identification of the ideal margins for mesenteric lymphadenectomy during bowel resection for colon cancer...
August 29, 2017: Techniques in Coloproctology
https://www.readbyqxmd.com/read/28831342/diagnostic-accuracy-of-lymphoscintigraphy-for-lymphedema-and-analysis-of-false-negative-tests
#9
Aladdin H Hassanein, Reid A Maclellan, Frederick D Grant, Arin K Greene
Lymphedema is the chronic enlargement of tissue due to inadequate lymphatic function. Diagnosis is made by history and physical examination and confirmed with lymphoscintigraphy. The purpose of this study was to assess the accuracy of lymphoscintigraphy for the diagnosis of lymphedema and to determine characteristics of patients with false-negative tests. METHODS: Individuals referred to our lymphedema program with "lymphedema" between 2009 and 2016 were analyzed. Subjects were assessed by history, physical examination, and lymphoscintigraphy...
July 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28819936/introducing-navigation-during-melanoma-related-sentinel-lymph-node-procedures-in-the-head-and-neck-region
#10
Gijs H KleinJan, Baris Karakullukçu, W Martin C Klop, Thijs Engelen, Nynke S van den Berg, Fijs W B van Leeuwen
BACKGROUND: Intraoperative sentinel node (SN) identification in patients with head-and-neck malignancies can be challenging due to unexpected drainage patterns and anatomical complexity. Here, intraoperative navigation-based guidance technologies may provide outcome. In this study, gamma camera-based freehandSPECT was evaluated in combination with the hybrid tracer ICG-(99m)Tc-nanocolloid. MATERIALS AND METHODS: Eight patients with melanoma located in the head-and-neck area were included...
August 17, 2017: EJNMMI Research
https://www.readbyqxmd.com/read/28780044/from-interventionist-imaging-to-intraoperative-guidance-new-perspectives-by-combining-advanced-tools-and-navigation-with-radio-guided-surgery
#11
S Vidal-Sicart, R Valdés Olmos, O E Nieweg, R Faccini, M R Grootendorst, H J Wester, N Navab, B Vojnovic, H van der Poel, S Martínez-Román, J Klode, F Wawroschek, F W B van Leeuwen
The integration of medical imaging technologies into diagnostic and therapeutic approaches can provide a preoperative insight into both anatomical (e.g. using computed tomography (CT), magnetic resonance (MR) imaging, or ultrasound (US)), as well as functional aspects (e.g. using single photon emission computed tomography (SPECT), positron emission tomography (PET), lymphoscintigraphy, or optical imaging). Moreover, some imaging modalities are also used in an interventional setting (e.g. CT, US, gamma or optical imaging) where they provide the surgeon with real-time information during the procedure...
August 3, 2017: Revista Española de Medicina Nuclear e Imagen Molecular
https://www.readbyqxmd.com/read/28775077/chronic-rejection-of-cardiac-allografts-is-associated-with-increased-lymphatic-flow-and-cellular-trafficking
#12
Lindsey A Edwards, Anna K Nowocin, Nazila V Jafari, Lucy Meader, Kathryn Brown, Aurélien Sarde, Carolyn Lam, Alex Murray, Wilson Wong
Background -Cardiac transplantation is an excellent treatment for end-stage heart disease. However, rejection of the donor graft, particularly by chronic rejection leading to cardiac allograft vasculopathy, remains a major cause of graft loss. The lymphatic system plays a crucial role in the alloimmune response, facilitating trafficking of antigen presenting cells (APCs) to draining lymph nodes (dLN). The encounter of APCs with T lymphocytes in secondary lymphoid organs is essential for the initiation of alloimmunity...
August 3, 2017: Circulation
https://www.readbyqxmd.com/read/28746237/abdominoplasty-with-lymphatic-microsurgery-for-patients-with-secondary-lower-extremity-lymphedema
#13
Shinsuke Akita, Yoshihisa Yamaji, Hideki Tokumoto, Naoki Adachi, Yoshitaro Sasahara, Yoshitaka Kubota, Motone Kuriyama, Nobuyuki Mitsukawa
BACKGROUND: Patients with secondary lower extremity lymphedema (LEL) often develop suprapubic lymphedema. We developed a novel surgical method of shaping the lower abdomen and debulking suprapubic lymphedema with simultaneous reconstruction of lymphatic flow in case of LEL. METHODS: A skin incision in a fleur-de-lis pattern was performed for horizontal and vertical abdominal skin and fat resection. A caudal-based isosceles triangular flap was created on the central suprapubic region to reduce wound tension at the intersection of the horizontal and vertical incisions...
July 12, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28740776/tc-99m-human-serum-albumin-transit-time-as-a-measure-of-arm-breast-cancer-related-lymphedema
#14
Navid M Toyserkani, Svend Hvidsten, Siavosh Tabatabaeifar, Jane A Simonsen, Poul F Høilund-Carlsen, Jens A Sørensen
BACKGROUND: Lymphoscintigraphy has often been used for evaluating arm lymphatic dysfunction, but no optimal approach for quantification has so far emerged. We propose a quantifiable measure of lymphatic function that we applied in patients treated for breast cancer. METHODS: Eleven patients, aged 34-68 years, with unilateral arm lymphedema following breast cancer treatment underwent bilateral lymphoscintigraphy using intradermal injection in both hands of technetium-99m-labeled human serum albumin and sequential 5 min imaging for 5 hours...
June 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28738392/multiple-lymph-node-basin-drainage-in-trunk-melanoma-is-not-associated-with-survival-of-sentinel-lymph-node-positive-patients
#15
Simone Ribero, Simona Osella Abate, Sadro Pasquali, Carlo Riccardo Rossi, Lorenzo Borgognoni, Dario Piazzalunga, Nicola Solari, Mauro Schiavon, Paola Brandani, Luca Ansaloni, Erica Ponte, Francesco Silan, Antonio Sommariva, Francesco Bellucci, Giuseppe Macripò, Pietro Quaglino
OBJECTIVES: This study was aimed at investigating the prognostic role of multiple lymph node basin drainage (MLBD) in patients with positive sentinel lymph node (SLN) biopsy. BACKGROUND: MLBD is frequently observed in patients with trunk melanoma undergoing SLN. The prognostic value of MLBD in SLN-positive patients is still debated. METHODS: Retrospective data from 312 trunk melanoma patients with positive SLN biopsy (1991-2012) at 6 Italian referral centres were gathered in a multicentre database...
July 25, 2017: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/28713733/effectiveness-of-preoperative-lymphoscintigraphy-for-the-detection-of-cervical-lymph-node-metastasis-in-patients-with-oral-squamous-cell-carcinoma
#16
Md Ahsan Habib, Quazi Billur Rahman, Shakhawat Hossain, Ashik Abdullah Imon, Gokul Chand Kundu
BACKGROUND: Oral squamous cell carcinoma (OSCC) is one of the most common malignant tumor. OSCC is the malignancy of squamous epithelium of oral cavity, which is the sixth most common malignancy reported worldwide and one with highest mortality rate among all malignancies. AIMS: The aims of this study is to assess the diagnostic performance of lymphoscintigraphy (LSG) for the detection of cervical lymph node metastasis in patients with OSCC. MATERIALS AND METHODS: This was a prospective study done in Oral and Maxillofacial Surgery Department and National Institute of Nuclear Medicine and Allied Science, Bangabandhu Sheikh Mujib Medical University during July 2015-June 2016...
January 2017: Annals of Maxillofacial Surgery
https://www.readbyqxmd.com/read/28705929/use-of-tc-99m-tilmanocept-as-a-single-agent-for-sentinel-lymph-node-identification-in-breast-cancer-a-retrospective-pilot-study
#17
Jonathan Takei Unkart, Anne Marie Wallace
Introduction: Tc-99m tilmanocept (TcTM) received recent FDA-approval for lymphatic mapping. However, no prior studies have evaluated the use of TcTM as a single agent in sentinel lymph node (SLN) biopsy in breast cancer. Methods: We executed this retrospective, pilot study to assess the ability of TcTM to identify sentinel nodes as a single agent in clinically node-negative breast cancer patients. Patients received a single, intradermal injection overlying the tumor of either 0.5 mCi TcTM the day-of surgery or 2...
July 13, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/28690675/development-of-sentinel-node-biopsy-roll-and-iart-in-early-breast-cancer-at-the-european-institute-of-oncology-milan-ieo
#18
REVIEW
Giovanni Paganelli
The problem of unnecessary axillary clearance in many patients with early breast cancer was certainly a major issue at IEO when we started working with Prof. Umberto Veronesi in 1994. At that time, axillary dissection in EBC was offered to all patients and this procedure was often hotly debated during our multidisciplinary breast cancer meetings. The question as to whether we could avoid axillary dissection by using PET scans or other nuclear medicine methods was frequently asked by Veronesi. This eventually prompted us to investigate whether, as for melanoma patients, the sentinel node biopsy (SNB) approach could reliably be applied to breast cancer...
2017: Ecancermedicalscience
https://www.readbyqxmd.com/read/28669886/correlation-between-lymphedema-disease-severity-and-lymphoscintigraphic-findings-a%C3%A2-clinical-radiologic-study
#19
Reid A Maclellan, David Zurakowski, Stephan Voss, Arin K Greene
BACKGROUND: Lymphoscintigraphy is used to confirm the diagnosis of lymphedema; pathologic findings are abnormal transit time to regional nodes and dermal backflow. A universal protocol for the test does not exist. The purpose of this study was to determine whether the clinical severity of lymphedema correlates with lymphoscintigraphy findings. STUDY DESIGN: Patients treated in our Lymphedema Program between 2009 and 2017 were reviewed. Diagnosis of lymphedema was determined by history, physical examination, and lymphoscintigraphy...
September 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/28664307/lymphocele-following-liposuction-in-the-thigh
#20
Qianwen Wang, Jiaqi Wang, Peng Li
Lymphocele has not been reported as a complication after liposuction. In this study, we present the case of a patient who developed a cystic lesion after liposuction in her right thigh. The cyst could contract and evolve. The diagnosis of pseudobursa seroma (late seroma) was first considered. However, lymphoscintigraphy showed that lymphatic fluid accumulated in the cyst, and lymphatic vessel connected with it. The final diagnose was a lymphocele. After interventional therapy and conservative treatment failed, the lymphocele was resected...
June 29, 2017: Aesthetic Plastic Surgery
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