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Lymphoscintigraphy

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https://www.readbyqxmd.com/read/29330718/spect-ct-adds-distinct-lymph-node-basins-and-influences-radiologic-findings-and-surgical-approach-for-sentinel-lymph-node-biopsy-in-head-and-neck-melanoma
#1
Becky B Trinh, Brandon C Chapman, Ana Gleisner, Jennifer J Kwak, Rustain Morgan, Martin D McCarter, Csaba Gajdos, Nicole Kounalakis
BACKGROUND: Planar lymphoscintigraphy (PL) has a lower detection rate of sentinel lymph nodes (SLNs) in head and neck melanoma compared with other sites. We assessed situations when single-photon emission computed tomography/computed tomography (SPECT/CT) identified nodes not seen by PL. We also evaluated the impact of SPECT/CT on surgical approach and oncologic outcomes. METHODS: Patients who underwent SLN biopsy (SLNB) for head and neck melanoma with PL and SPECT/CT between November 2011 and December 2016 were included...
January 12, 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29310388/lymphedema-secondary-to-idiopathic-occlusion-of-the-subclavian-and-innominate-veins-after-renal-transplantation-a-case-report
#2
Yong Min Kim, Chul Moon, Dong Erk Goo, Soo Bin Park, Ji Woong Park
RATIONALE: Among the causes of swelling in the extremities of renal transplantation patients, secondary lymphedema caused by complete idiopathic obstruction of large veins is rare and may be difficult to diagnose and treat. PATIENT CONCERNS: A 64-year-old man presented with severe edema and pain that occurred suddenly in the right arm. DIAGNOSES: The patient was diagnosed as stage-2 secondary lymphedema caused by idiopathic occlusion of the subclavian and innominate veins...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29306049/evaluation-of-lymphedema-in-upper-extremities-by-mr-lymphangiography-comparison-with-lymphoscintigraphy
#3
Jae Seok Bae, Roh-Eul Yoo, Seung Hong Choi, Seong Oh Park, Hak Chang, Minseok Suh, Gi Jeong Cheon
PURPOSE: To validate usefulness of magnetic resonance (MR) lymphangiography for evaluation of peripheral lymphedema in upper extremities by comparison with lymphoscintigraphy. MATERIALS AND METHODS: This prospective study had institutional review board approval and written informed consent was obtained from all patients. Initially, protocol of MR lymphangiography for upper extremity was established in seven healthy volunteers with 3.0T fat-saturated three-dimensional gradient-echo MR after gadobutrol injection...
January 3, 2018: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/29304140/long-term-effects-of-manual-lymphatic-drainage-and-active-exercises-on-physical-morbidities-lymphoscintigraphy-parameters-and-lymphedema-formation-in-patients-operated-due-to-breast-cancer-a-clinical-trial
#4
Mariana Maia Freire de Oliveira, Maria Salete Costa Gurgel, Bárbara Juarez Amorim, Celso Dario Ramos, Sophie Derchain, Natachie Furlan-Santos, César Cabello Dos Santos, Luís Otávio Sarian
PURPOSE: evaluate whether manual lymphatic drainage (MLD) or active exercise (AE) is associated with shoulder range of motion (ROM), wound complication and changes in the lymphatic parameters after breast cancer (BC) surgery and whether these parameters have an association with lymphedema formation in the long run. METHODS: Clinical trial with 106 women undergoing radical BC surgery, in the Women's Integrated Healthcare Center-University of Campinas. Women were matched for staging, age and body mass index and were allocated to performed AE or MLD, 2 weekly sessions during one month after surgery...
2018: PloS One
https://www.readbyqxmd.com/read/29289416/lymphatic-transit-rate-as-a-predictive-parameter-for-nodal-metastasis-in-primary-limb-malignant-melanoma
#5
Masao Fujiwara, Takahiro Suzuki, Akira Kasuya, Takatoshi Shimauchi, Hidekazu Fukamizu, Yoshiki Tokura
BACKGROUND: The status of sentinel lymph node (SLN) is one of the most predictive prognostic factors in patients with clinically localized malignant melanomas (MMs). However, since the positive SLN metastatic rate is as low as 20%, it is desirable to minimize SLN biopsy performance with imaging. By dynamic lymphoscintigraphy, we have proposed the lymphatic transit rate (LTR), the value that the distance between the primary lesion and SLN is divided by scintigraphic saturation time. LTR represents the scintigraphic saturation velocity and can be used for evaluation of metastasis of skin cancers...
December 24, 2017: Journal of Dermatological Science
https://www.readbyqxmd.com/read/29242730/unusual-contralateral-axillary-lymph-node-metastasis-in-a-second-primary-breast-cancer-detected-by-fdg-pet-ct-and-lymphoscintigraphy
#6
Ji-Young Kim, Hyunjong Lee, Tae Sung Kim, Han-Sung Kang, Seok-Ki Kim
Contralateral metastatic axillary lymph nodes in a patient with breast cancer is a rare condition. Here, we present a 55-year-old woman with a second primary breast cancer. The patient underwent 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) for staging work-up. Additionally, preoperative lymphoscintigraphy was performed to detect sentinel lymph nodes. FDG PET/CT demonstrated increased FDG uptake in the left nipple and right axillary lymph nodes. Lymphoscintigraphy identified the right axillary lymph nodes which was consistent with the FDG PET/CT findings...
December 2017: Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/29223390/lymphatic-drainage-from-renal-tumors-in-vivo-a-prospective-sentinel-node-study-using-spect-ct-imaging
#7
Teele Kuusk, Roderick De Bruijn, Oscar Brouwer R, Jeroen De Jong, Maarten Donswijk, Nikolaos Grivas, Kees Hendricksen, Simon Horenblas, Warner Prevoo, Olmos A Renato Valdés, Poel G Henk Van Der, Rhijn Wg Bas Van, Esther Wit M, Axel Bex
PURPOSE: Lymphatic drainage from renal tumors is unpredictable and in vivo drainage studies of primary lymphatic landing sites may reveal the variability and dynamics of lymphatic connections. The purpose of this study was to investigate the lymphatic drainage pattern from renal tumors in vivo with SPECT/CT imaging after intra-tumoral radiotracer injection. MATERIALS AND METHODS: We conducted a phase II prospective single-arm study to investigate the distribution of SNs from renal tumors on SPECT/CT imaging...
December 6, 2017: Journal of Urology
https://www.readbyqxmd.com/read/29216739/lymphatic-drainage-efficiency-a-new-parameter-of-lymphatic-function
#8
Georgia Keramida, Emma Wroe, Nicola Winterman, Mark Aplin, A Michael Peters
Background Following convection from blood capillaries, plasma proteins are transported to loco-regional lymph nodes in two stages: first, uptake into peripheral lymphatics, and second, transport to nodes. Purpose To introduce a new parameter of lymphatic function that quantifies stage 2 - lymphatic drainage efficiency (LDE). Material and Methods Percentage injected activity (IIQ) in ilio-inguinal nodes 150 min following subcutaneous foot web-space injection of Tc-99 m-nanocolloid was measured in 102 patients undergoing lymphoscintigraphy using a method in which a standard is placed by image guidance over the nodes...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/29196357/an-approach-to-familial-lymphoedema
#9
Gabriela E Jones, Sahar Mansour
Lymphoedema is the build-up of lymphatic fluid leading to swelling in the tissues. Most commonly it affects the peripheries. Diagnosis is based on clinical assessment and imaging with lymphoscintigraphy. Treatment is supportive with compression garments, massage, good skin hygiene and prompt use of antibiotics to avoid the complication of cellulitis. Most commonly, lymphoedema occurs as a result of damage to the lymphatic system following surgery, trauma, radiation or infection. However, it can be primary, often associated with a genetic defect that causes disruption to the development of the lymphatic system...
December 2017: Clinical Medicine: Journal of the Royal College of Physicians of London
https://www.readbyqxmd.com/read/29189931/preoperative-sentinel-lymph-node-localization-in-vulvar-cancer-preliminary-experience-with-inguinal-intradermal-contrast-enhanced-ultrasound
#10
O Lahtinen, M Eloranta, M Anttila, H Kärkkäinen, R Sironen, R Vanninen, S Rautiainen
OBJECTIVE: To evaluate the feasibility and diagnostic performance of intradermal contrast-enhanced ultrasound (CEUS) sentinel lymph node (SLN) procedure in vulvar cancer. METHODS: Twelve consecutive patients with vulvar cancer underwent preoperatively inguinal CEUS SLN examination and guide wire marking of the enhanced lymph nodes. Altogether, 20 groins were examined with CEUS contrast agent injections including 8 bilateral groins due to midline tumours. One groin was excluded due to previous inguinal surgery...
November 30, 2017: European Radiology
https://www.readbyqxmd.com/read/29178426/the-role-of-sentinel-lymph-node-mapping-in-small-animal-veterinary-medicine-a-comparison-with-current-approaches-in-human-medicine
#11
P Beer, A Pozzi, C Rohrer Bley, N Bacon, N S Pfammatter, C Venzin
The relevance of regional lymph node (LN) assessment to quantify the metastatic spread of cancer is well recognized in veterinary oncology. Evaluation of LNs is critical for tumour staging. However, sampling the correct LN may not be possible without sentinel lymph node (SLN) mapping. Methods for diagnostic imaging and intraoperative detection of SLNs are well established in human medicine, in particular, the combination of lymphoscintigraphy and intraoperative application of blue dyes. Nevertheless, alternative imaging techniques are available and have gained increasing interest...
November 27, 2017: Veterinary and Comparative Oncology
https://www.readbyqxmd.com/read/29119692/impact-of-same-day-vs-day-before-pre-operative-lymphoscintigraphy-for-sentinel-lymph-node-biopsy-for-early-breast-cancer-local-australian-experience
#12
Yang Yang Huang, Amelie Maurel, Saud Hamza, Lee Jackson, Zeyad Al-Ogaili
INTRODUCTION: To assess the impact of delayed vs immediate pre-operative lymphoscintigraphy (LSG) for sentinel lymph node biopsy in a single Australian tertiary breast cancer centre. METHODS: Retrospective cohort study analysing patients with breast cancer or DCIS who underwent lumpectomy or mastectomy with pre-operative LSG and intra-operative sentinel lymph node biopsy from January 2015 to June 2016. RESULTS: A total of 182 LSG were performed...
November 9, 2017: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/29106918/use-of-intraoperative-nuclear-imaging-leads-to-decreased-anesthesia-time-and-real-time-confirmation-of-lesion-removal
#13
Joseph C Fusco, Brittani K N Seynnaeve, Alexander J Davit, Michael R Czachowski, Judith M Joyce, Barbara A Gaines, Marcus M Malek
BACKGROUND: Lymphatic mapping to guide sentinel lymph node biopsy (SLNB) typically requires lymphoscintigraphy prior to surgery. In young pediatric patients, this process often requires intubation in the nuclear medicine suite followed by transport to the operating room (OR). METHODS: We reviewed 14 pediatric cases in which a portable nuclear imaging camera was utilized to perform the entirety of the SLNB in the OR. RESULTS AND CONCLUSION: This method, utilizing intraoperative nuclear imaging, helped to confirm removal of the sentinel lymph node in real time, decreased anesthesia time, and avoided transport of a sedated or intubated child...
October 9, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29059186/lymphatic-pathology-in-asymptomatic-and-symptomatic-children-with-wuchereria-bancrofti-infection-in-children-from-odisha-india-and-its-reversal-with-dec-and-albendazole-treatment
#14
RANDOMIZED CONTROLLED TRIAL
Shantanu K Kar, Bhagirathi Dwibedi, Birendra K Das, Bikash K Agrawala, Cherubala P Ramachandran, John Horton
BACKGROUND: Once interruption of transmission of lymphatic filariasis is achieved, morbidity prevention and management becomes more important. A study in Brugia malayi filariasis from India has shown sub-clinical lymphatic pathology with potential reversibility. We studied a Wuchereria bancrofti infected population, the major contributor to LF globally. METHODS: Children aged 5-18 years from Odisha, India were screened for W. bancrofti infection and disease. 102 infected children, 50 with filarial disease and 52 without symptoms were investigated by lymphoscintigraphy and then randomized to receive a supervised single oral dose of DEC and albendazole which was repeated either annually or semi-annually...
October 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29036002/multimodal-imaging-in-klippel-tr%C3%A3-naunay-weber-syndrome-clinical-photography-computed-tomoangiography-infrared-thermography-and-99mtc-phytate-lymphoscintigraphy
#15
Su Wan Kim, Heesung Song
We report the case of a 19-year-old man who presented with a 12-year history of progressive fatigue, feeling hot, excessive sweating, and numbness in the left arm. He had undergone multimodal imaging and was diagnosed as having Klippel-Trénaunay-Weber syndrome (KTWS). This is a rare congenital disease, defined by combinations of nevus flammeus, venous and lymphatic malformation, and hypertrophy of the affected limbs. Lower extremities are affected mostly. Conventional modalities for evaluating KTWS are ultrasonography, CT, MRI, lymphoscintigraphy, and angiography...
October 13, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29033684/fluorine-18-2-fluoro-2-deoxy-d-glucose-positron-emission-tomography-computed-tomography-masquerading-as-a-case-of-sporadic-malignant-peripheral-nerve-sheath-tumor-of-lower-extremity-presenting-as-massive-lower-limb-edema
#16
Deepa Singh, Rajender Kumar, Ashim Das, Subhash C Varma, Bhagwant R Mittal
Malignant peripheral nerve sheath tumors (MPNSTs) are rare neuroectodermal tumors resulting from the malignant transformation of benign plexiform neurofibromas. The sporadic form of these tumors is rare than familial variants (seen in neurofibromatosis Type 1) and making the diagnosis difficult. We are presenting a case of 40--year-old female with the complaint of progressive swelling of lower limb with initial suspicion of lymphedema and underwent lymphoscintigraphy, magnetic resonance imaging, and finally fluorine-18-2-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography scans were done to rule out mitotic etiology and extent of the disease...
October 2017: World Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28975889/the-evolution-of-the-sentinel-node-procedure-in-the-treatment-of-breast-cancer
#17
Tove Filtenborg Tvedskov
This thesis is based on 10 original articles, of which 3 were previously included in the PhD thesis "Staging of women with breast cancer after introduction of sentinel node guided axillary dissection". In the PhD thesis is was shown that the introduction of sentinel lymph node dissection (SLND) in the treatment of breast cancer in Denmark has resulted in an increased identification of patients with micrometastases or isolated tumor cells (ITC) in the lymph nodes. Not all these small metastases are likely to disseminate to non-sentinel nodes...
October 2017: Danish Medical Journal
https://www.readbyqxmd.com/read/28961075/indocyanine-green-lymphographic-and-lymphoscintigraphic-findings-in-genital-lymphedema-genital-pathway-score
#18
Hisako Hara, Makoto Mihara
BACKGROUND: Although genital lymphedema is a challenging disease, its mechanism is unclear. The aim of this study was to identify the lymphatic flow in genital lymphedema and establish a suitable examination for genital lymphedema. METHODS: We injected phytic acid or albumin labeled with (99m)Tc at the bilateral first web spaces of the feet of 47 patients for lymphoscintigraphy. For indocyanine green (ICG) lymphography, we injected ICG into the first web spaces of both feet and other points if necessary...
September 29, 2017: Lymphatic Research and Biology
https://www.readbyqxmd.com/read/28931417/sentinel-lymph-node-biopsy-in-periocular-merkel-cell-carcinoma-a-case-report
#19
Dan C Filitis, Gyorgy Paragh, Faramarz H Samie, Nathalie C Zeitouni
BACKGROUND: The National Comprehensive Cancer Network guidelines for Merkel cell carcinoma recommend performance of the sentinel lymph node biopsy in all patients with clinically negative nodal disease for staging and treatment. Nevertheless, sentinel lymph node biopsy in the periocular region is debated as tumors are typically smaller and lymphatic variability can make performance procedurally problematic. CASE PRESENTATION: We present a case of a Caucasian patient in their seventies who presented with a 1...
September 20, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28913301/concordant-surgical-treatment-non-melanocytic-skin-cancer-of-the-head-and-neck
#20
Wan Cheol Ryu, In Chang Koh, Yong Hae Lee, Jong Hyun Cha, Sang Il Kim, Chang Gyun Kim
BACKGROUND: Skin cancer is the most common type of cancer. Of the 4 million skin lesions excised annually worldwide, approximately 2 million are considered cancerous. In this study, we aimed to describe a regional experience with skin cancers treated by a single senior surgeon and to provide a treatment algorithm. METHODS: The medical records of 176 patients with head and neck non-melanocytic skin cancer (NMSC) who were treated by a single surgeon at our institution between January 2010 and May 2016 were retrospectively reviewed, and their data (age, sex, pathological type, tumor location/size, treatment modality) were analyzed...
March 2017: Archives of Craniofacial Surgery
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