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https://www.readbyqxmd.com/read/28227762/single-shot-turbo-spin-echo-acquisition-for-in-vivo-cardiac-diffusion-mri
#1
Masoud Edalati, Gregory R Lee, Hui Wang, Michael D Taylor, Yu Y Li, Masoud Edalati, Gregory R Lee, Hui Wang, Michael D Taylor, Yu Y Li, Masoud Edalati, Gregory R Lee, Michael D Taylor, Hui Wang, Yu Y Li
Diffusion MRI offers the ability to noninvasively characterize the microstructure of myocardium tissue and detect disease related pathology in cardiovascular examination. This study investigates the feasibility of in vivo cardiac diffusion MRI under free-breathing condition. A high-speed imaging technique, correlation imaging, is used to enable single-shot turbo spin echo for free-breathing cardiac data acquisition. The obtained in vivo cardiac diffusion-weighted images illustrate robust image quality and minor geometry distortions...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227675/investigating-an-alternative-ring-design-of-transducer-arrays-for-tumor-treating-fields-ttfields
#2
Mario Macedo, Cornelia Wenger, Ricardo Salvador, Sofia R Fernandes, Pedro C Miranda, Mario Macedo, Cornelia Wenger, Ricardo Salvador, Sofia R Fernandes, Pedro C Miranda, Sofia R Fernandes, Pedro C Miranda, Cornelia Wenger, Ricardo Salvador, Mario Macedo
Tumor treating fields (TTFields) is a therapy that inhibits cell proliferation and has been approved by the U.S Food and Drug Administration (FDA) for the treatment of Glioblastoma Multiforme. This anti-mitotic technique works non-invasively and regionally, and is associated with less toxicity and a better quality of life. Currently a device called Optune™ is clinically used which works with two perpendicular and alternating array pairs each consisting of 3×3 transducers. The aim of this study is to investigate a theoretical alternative array design which consists of two rings of 16 transducers and thus permits various field directions...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227549/prediction-of-microsleeps-from-eeg-preliminary-results
#3
Reza Shoorangiz, Stephen J Weddell, Richard D Jones, Reza Shoorangiz, Stephen J Weddell, Richard D Jones, Stephen J Weddell, Reza Shoorangiz, Richard D Jones
Brief episodes of momentarily falling asleep - microsleeps - can have fatal consequences, especially in the transportation sector. In this study, the EEG data of eight subjects, while performing a 1-D tracking task, were used to predict imminent microsleeps. A novel algorithm was developed to improve the accuracy of microsleep identification from two independent measures: tracking performance and face-video. The uncertain labels of gold-standard were then pruned out. Additionally, the state of microsleep at 0...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227469/building-a-more-diverse-biomedical-engineering-workforce-biomedical-engineering-at-the-university-of-the-district-of-columbia-a-historically-black-college-university
#4
Lara A Thompson, A Segun Adebayo, Nian Zhang, Sasan Haghani, Kathleen Dowell, Devdas Shetty, Lara A Thompson, A Segun Adebayo, Nian Zhang, Sasan Haghani, Kathleen Dowell, Devdas Shetty, A Segun Adebayo, Sasan Haghani, Kathleen Dowell, Lara A Thompson, Devdas Shetty, Nian Zhang
Biomedical Engineering (BME) is a new, multidisciplinary, and rapidly growing field, however, the BME Workforce suffers from limited ethnic and gender diversity. Despite the demand and growth of this new field due to its public health importance, only 4 out of the 107 Historically Black Colleges and Universities (HBCUs) nationwide offers a Bachelor's of Science (B.S.) in Bio-Engineering related fields. In order to contribute to a growing BME Workforce, HBCUs need to react and offer more degree-programs relevant to BME...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227328/effect-of-importance-sampling-on-robust-segmentation-of-audio-cough-events-in-noisy-environments
#5
Jesus Monge-Alvarez, Carlos Hoyos-Barcelo, Paul Lesso, Javier Escudero, Keshav Dahal, Pablo Casaseca-de-la-Higuera, Jesus Monge-Alvarez, Carlos Hoyos-Barcelo, Paul Lesso, Javier Escudero, Keshav Dahal, Pablo Casaseca-de-la-Higuera, Javier Escudero, Jesus Monge-Alvarez, Keshav Dahal, Carlos Hoyos-Barcelo, Pablo Casaseca-De-La-Higuera, Paul Lesso
This paper proposes a new cough detection system based on audio signals acquired from conventional smartphones. The system relies on local Hu moments to characterize cough events and a Λ-NN classifier to distinguish cough events from non-cough ones (speech, laugh, sneeze, etc.) and noisy sounds. To deal with the unbalance between classes, we employ Distinct-Borderline2 Synthetic Minority Oversampling Technique and a bespoke cost matrix. The system additionally features a post-processing module to avoid isolated false negatives and, this way, increases sensitivity...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227212/classification-of-large-scale-fundus-image-data-sets-a-cloud-computing-framework
#6
Sohini Roychowdhury, Sohini Roychowdhury, Sohini Roychowdhury
Large medical image data sets with high dimensionality require substantial amount of computation time for data creation and data processing. This paper presents a novel generalized method that finds optimal image-based feature sets that reduce computational time complexity while maximizing overall classification accuracy for detection of diabetic retinopathy (DR). First, region-based and pixel-based features are extracted from fundus images for classification of DR lesions and vessel-like structures. Next, feature ranking strategies are used to distinguish the optimal classification feature sets...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226741/automated-detection-of-neovascularization-for-proliferative-diabetic-retinopathy-screening
#7
Sohini Roychowdhury, Dara D Koozekanani, Keshab K Parhi, Sohini Roychowdhury, Dara D Koozekanani, Keshab K Parhi, Dara D Koozekanani, Keshab K Parhi, Sohini Roychowdhury
Neovascularization is the primary manifestation of proliferative diabetic retinopathy (PDR) that can lead to acquired blindness. This paper presents a novel method that classifies neovascularizations in the 1-optic disc (OD) diameter region (NVD) and elsewhere (NVE) separately to achieve low false positive rates of neovascularization classification. First, the OD region and blood vessels are extracted. Next, the major blood vessel segments in the 1-OD diameter region are classified for NVD, and minor blood vessel segments elsewhere are classified for NVE...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226610/data-driven-estimation-of-blood-pressure-using-photoplethysmographic-signals
#8
Shi Chao Gao, Peter Wittek, Li Zhao, Wen Jun Jiang, Shi Chao Gao, Peter Wittek, Li Zhao, Wen Jun Jiang, Shi Chao Gao, Peter Wittek, Li Zhao, Wen Jun Jiang
Noninvasive measurement of blood pressure by optical methods receives considerable interest, but the complexity of the measurement and the difficulty of adjusting parameters restrict applications. We develop a method for estimating the systolic and diastolic blood pressure using a single-point optical recording of a photoplethysmographic (PPG) signal. The estimation is data-driven, we use automated machine learning algorithms instead of mathematical models. Combining supervised learning with a discrete wavelet transform, the method is insensitive to minor irregularities in the PPG waveform, hence both pulse oximeters and smartphone cameras can record the signal...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226418/omalizumab-for-the-treatment-of-chronic-idiopathic-urticaria-systematic-review-of-the-literature
#9
Alessandro Tonacci, Lucia Billeci, Giovanni Pioggia, Michele Navarra, Sebastiano Gangemi
Omalizumab is recombinant humanized monoclonal antibody to immunoglobulin E. Guidelines for the treatment of chronic idiopathic urticaria (also known as chronic spontaneous urticaria) recommend the use of omalizumab as third-line therapy in addition to high doses of histamine receptor type 1 (H1 ) antihistamines when they are unsuccessful as first- and second-line therapy. We performed a systematic review of the literature to identify studies that evaluated the efficacy of omalizumab for the treatment of chronic idiopathic urticaria, both in controlled and real-world settings, to assess its potential role as a preferred therapy...
February 22, 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/28226411/the-control-of-eye-movements-by-the-cerebellar-nuclei-polysynaptic-projections-from-the-fastigial-interpositus-posterior-and-dentate-nuclei-to-lateral-rectus-motoneurons-in-primates
#10
Vincent Prevosto, Werner Graf, Gabriella Ugolini
Premotor circuits driving extraocular motoneurons and downstream motor outputs of cerebellar nuclei are well known. However, there is, as yet, no unequivocal account of cerebellar output pathways controlling eye movements in primates. Using retrograde transneuronal transfer of rabies virus from the lateral rectus (LR) eye muscle, we studied polysynaptic pathways to LR motoneurons in primates. Injections were placed either into the central or distal muscle portion, to identify innervation differences of LR motoneurons supplying singly innervated (SIFs) or multiply innervated muscle fibers (MIFs)...
February 22, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28226307/racial-ethnic-and-weight-status-disparities-in-dieting-and-disordered-weight-control-behaviors-among-early-adolescents
#11
Rachel F Rodgers, Karen E Peterson, Anne T Hunt, Jennifer L Spadano-Gasbarro, Tracy K Richmond, Mary L Greaney, S Bryn Austin
BACKGROUND: This study examined whether racial/ethnic minority early adolescents with overweight/obesity are at increased risk of disordered weight control behaviors, defined as unhealthy behaviors aiming to control or modify shape and weight, ranging from self-induced vomiting to the use of dietary supplements. METHODS: U.S. Middle school children (n=12.511) provided self-report of gender, race/ethnicity, height, and weight as well as dieting and disordered weight control behaviors...
February 14, 2017: Eating Behaviors
https://www.readbyqxmd.com/read/28226304/positive-comments-negative-outcomes-the-potential-downsides-of-appearance-related-commentary-in-ethnically-diverse-women
#12
Sylvia Herbozo, Steven D Stevens, Christina P Moldovan, Holly E R Morrell
Although research has shown that appearance-related commentary influences body dissatisfaction and disordered eating, limited research has studied such commentary among ethnically diverse women. The current study examined ethnic group differences in the frequency and impact of appearance-related commentary and associations with body dissatisfaction and eating disorder psychopathology. Participants included 280 undergraduate women aged 18-25 (56.1% European American, 28.6% African American, and 15.3% Latina American)...
February 19, 2017: Body Image
https://www.readbyqxmd.com/read/28226283/social-ecological-correlates-of-polyvictimization-among-a-national-sample-of-transgender-genderqueer-and-cisgender-sexual-minority-adolescents
#13
Paul R Sterzing, G Allen Ratliff, Rachel E Gartner, Briana L McGeough, Kelly C Johnson
Polyvictimization is a common experience for youth in the United States, with 20% nationally experiencing five or more different forms of victimization in the last year. Utilizing a large, national convenience sample of sexual and gender minority adolescents (N = 1177, 14-19 years old), the current study aimed to (a) generate the first estimates of last year polyvictimization (including nine victimization subtypes) for transgender, genderqueer, and cisgender (i.e., assigned birth sex aligns with gender identity) sexual minority adolescents and (b) identify social ecological correlates of last year polyvictimization...
February 18, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/28226269/the-causes-and-consequences-of-dna-methylome-variation-in-plants
#14
REVIEW
Danelle K Seymour, Claude Becker
Epigenetic variation - polymorphisms at the level of DNA methylation or histone modifications - modulates chromatin accessibility, which can perturb transcriptional activity and spur phenotypic variation. Determining the origin, frequency spectrum, and consequences of epigenetic variants is key to understanding the role of this variation in generating stable phenotypic variation in plants. Here we review recent literature on DNA methylation variation in both model and crop plant species with a focus on the link between genotype, epigenotype, and transcription...
February 19, 2017: Current Opinion in Plant Biology
https://www.readbyqxmd.com/read/28226267/a-simple-lc-ms-ms-method-for-the-simultaneous-quantification-of-resveratrol-and-its-major-phase-ii-metabolites-assessment-of-their-urinary-and-biliary-excretions-in-rats
#15
Zhixia Qiu, Jiaojiao Yu, Yu Dai, Xijing Chen, Fang Huang, Ning Li
Trans-resveratrol (Res) is rapidly metabolized, extensively distributed into various tissues and mainly excreted by urine. The present study aimed to establish a simple LC-MS/MS method to simultaneously quantify Res and its major phase II metabolites (Res-3-O-β-d-glucuronide, R3G; Res-4'-O-β-d-glucuronide, R4'G; Res-resveratrol 3-sulfate, R3S; and Res-4'-sulfate, R4'S), and apply this method to assess their urinary and biliary excretions in rats. A simplified salting-out assisted liquid-liquid extraction (SALLE) strategy was developed to prepare samples with acetonitrile-methanol mixture (8:2, v/v) as extractant and ammonium acetate solution (10M) as salting-out reagent...
February 14, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28226076/treatment-of-hemifacial-spasm-with-botulinum-toxin-type-a-effective-long-lasting-and-well-tolerated
#16
Jean Pierre Mette Batisti, Alais Daiane Fadini Kleinfelder, Natália Bassalobre Galli, Adriana Moro, Renato Puppi Munhoz, Hélio Afonso Ghizoni Teive
Objective: To evaluate the long-term effect of botulinum toxin type A (BTX-A) in the treatment of HFS. Methods: A retrospective analysis of patients treated at the Movement Disorders Outpatient Clinic in the Neurology Service, Hospital de Clínicas, Federal University of Paraná, Curitiba, from 2009 to 2013 was carried out. A total of 550 BTX-A injections were administered to 100 HFS patients. Results: Mean duration of improvement following each injection session was 3...
February 2017: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/28225707/nonadherence-to-antiretroviral-therapy-among-hiv-infected-patients-in-zambia-is-concentrated-among-a-minority-of-patients-and-is-highly-variable-across-clinics
#17
Nancy L Czaicki, Charles B Holmes, Izukanji Sikazwe, Carolyn Bolton, Theodora Savory, Mwanza Wa Mwanza, Crispin Moyo, Nancy S Padian, Elvin H Geng
OBJECTIVES: The distribution of adherence to antiretroviral therapy (ART) can indicates whether barriers are concentrated or more distributed. We quantified the medication possession ratio (MPR) and characterized the distribution of medication nonpossession in a network of clinics in Zambia to identify 'hotspots' and predictors of poorer adherence. METHODS: We analyzed a population of adults on ART for more than 3 months who made at least one clinic visit between 1 January 2013 and 28 February 2015...
March 13, 2017: AIDS
https://www.readbyqxmd.com/read/28225661/lgbtq-youth-part-1
#18
Tracy Perron, Connie Kartoz, Chaya Himelfarb
In order to provide holistic care, school nurses must be culturally competent by being sensitive to health disparities experienced by students in at-risk populations. Despite the growing acceptance toward gender and sexual minorities, LGBTQ youth remain an at-risk population in our communities and our schools. School nurses as well as school counselors, social workers, and psychologists can increase their cultural competence in caring for this group of students by increasing their understanding of appropriate terminology and risks associated with this vulnerable group...
March 2017: NASN School Nurse
https://www.readbyqxmd.com/read/28225600/kinetics-and-mechanism-of-ultrasonic-activation-of-persulfate-an-in-situ-epr-spin-trapping-study
#19
Zongsu Wei, Frederick A Villamena, Linda K Weavers
Ultrasound (US) was shown to activate persulfate (PS) providing an alternative activation method to base or heat as an in-situ chemical oxidation (ISCO) method. The kinetics and mechanism of ultrasonic activation of PS were examined in aqueous solution using an in-situ electron paramagnetic resonance (EPR) spin trapping technique and radical trapping with probe compounds. Using the spin trap, 5,5-dimethyl-1-pyrroline-N-oxide (DMPO), hydroxyl radical (•OH) and sulfate radical anion (SO4•‒) were measured from ultrasonic activation of persulfate (US-PS)...
February 22, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28225587/compms2miner-an-automatable-metabolite-identification-visualization-and-data-sharing-r-package-for-high-resolution-lc-ms-datasets
#20
William Matthew Bell Edmands, Lauren M Petrick, Dinesh Kumar Barupal, Augustin Scalbert, Mark Wilson, Jeffrey Wickliffe, Stephen M Rappaport
A long-standing challenge of untargeted metabolomic profiling by ultrahigh performance liquid chromatography-high resolution mass spectrometry (UHPLC-HRMS) is efficient transition from unknown mass spectral features to confident metabolite annotations. The compMS2Miner (Comprehensive MS2 Miner) package was developed in the R language to facilitate rapid, comprehensive feature annotation using a peak-picker-output and MS2 data files as inputs. The number of MS2 spectra that can be collected during a metabolomic profiling experiment far outweigh the amount of time required for pain-staking manual interpretation, therefore a degree of software workflow autonomy is required for broad-scale metabolite annotation...
February 22, 2017: Analytical Chemistry
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