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https://www.readbyqxmd.com/read/28343343/child-and-adult-factors-related-to-quality-of-life-in-adults-with-autism
#1
Philippa Moss, William Mandy, Patricia Howlin
The WHO Quality of Life-Brief questionnaire was used to assess quality of life (QoL) among 52 adults with autism (mean age 49 years) followed-up since childhood. Overall, assessments of QOL were more positive than measures of objective social outcome (jobs, independence, relationships etc.) but correlations between caregiver and self-reports were low. Informant ratings indicated few correlations between current QoL and any child or adult factors. On self-report ratings, QoL was significantly negatively correlated with severity of repetitive behaviours in childhood; higher QoL was positively associated with better adult social outcomes...
March 25, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/28343283/the-types-of-trust-involved-in-american-muslim-healthcare-decisions-an-exploratory-qualitative-study
#2
Aasim I Padela, Liese Pruitt, Saleha Mallick
Trust in physicians and the healthcare system underlies some disparities noted among minority populations, yet a descriptive typology of different types of trust informing healthcare decisions among minority populations is limited. Using data from 13 focus groups with 102 American Muslims, we identified the types and influence of trust in healthcare decision-making. Participants conveyed four types of trust implicating their health-seeking behaviors-(I) trust in allopathic medicine, (II) trust in God, (III) trust in personal relationships, and (IV) trust in self...
March 25, 2017: Journal of Religion and Health
https://www.readbyqxmd.com/read/28343247/development-of-a-qtl-environment-based-predictive-model-for-node-addition-rate-in-common-bean
#3
Li Zhang, Salvador A Gezan, C Eduardo Vallejos, James W Jones, Kenneth J Boote, Jose A Clavijo-Michelangeli, Mehul Bhakta, Juan M Osorno, Idupulapati Rao, Stephen Beebe, Elvin Roman-Paoli, Abiezer Gonzalez, James Beaver, Jaumer Ricaurte, Raphael Colbert, Melanie J Correll
This work reports the effects of the genetic makeup, the environment and the genotype by environment interactions for node addition rate in an RIL population of common bean. This information was used to build a predictive model for node addition rate. To select a plant genotype that will thrive in targeted environments it is critical to understand the genotype by environment interaction (GEI). In this study, multi-environment QTL analysis was used to characterize node addition rate (NAR, node day(- 1)) on the main stem of the common bean (Phaseolus vulgaris L)...
March 25, 2017: TAG. Theoretical and Applied Genetics. Theoretische und Angewandte Genetik
https://www.readbyqxmd.com/read/28343220/hemorrhagic-transformations-after-thrombectomy-risk-factors-and-clinical-relevance
#4
Johannes Kaesmacher, Mirjam Kaesmacher, Christian Maegerlein, Claus Zimmer, Alexandra S Gersing, Silke Wunderlich, Benjamin Friedrich, Tobias Boeckh-Behrens, Justus F Kleine
BACKGROUND: Hemorrhagic transformation (HT) is a major complication of acute ischemic stroke, potentially associated with clinical deterioration. We attempted to identify risk factors and evaluated clinical relevance of minor and major HTs following endovascular thrombectomy (ET) in isolated middle cerebral artery (MCA) occlusions. METHODS: This is a retrospective single-center analysis of 409 patients with isolated MCA occlusion treated with ET. Patients' and procedural characteristics, severity of HT according to the European Cooperative Acute Stroke Study criteria, and clinical outcomes were analyzed...
March 25, 2017: Cerebrovascular Diseases
https://www.readbyqxmd.com/read/28343088/pathway-of-protection-ethnic-identity-self-esteem-and-substance-use-among-multiracial-youth
#5
Sycarah Fisher, Tamika C B Zapolski, Chelsea Sheehan, Jessica Barnes-Najor
Fifty percent of adolescents have tried an illicit drug and 70% have tried alcohol by the end of high school, with even higher rates among multiracial youth. Ethnic identity is a protective factor against substance use for minority groups. However, little is known about the mechanisms that facilitate its protective effects, and even less is known about this relationship for multiracial youth. The purpose of the present study was to examine the protective effect of ethnic identity on substance use and to determine whether this relationship operated indirectly through self-esteem, a strong predictor of substance use for among adolescent populations...
March 9, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28343021/application-of-mixed-methods-design-in-community-engaged-research-lessons-learned-from-an-evidence-based-intervention-for-latinos-with-chronic-illness-and-minor-depression
#6
Claudia X Aguado Loi, Moya L Alfonso, Isabella Chan, Kelsey Anderson, Dinorah Dina Martinez Tyson, Junius Gonzales, Jaime Corvin
The purpose of this paper is to share lessons learned from a collaborative, community-informed mixed-methods approach to adapting an evidence-based intervention to meet the needs of Latinos with chronic disease and minor depression and their family members. Mixed-methods informed by community-based participatory research (CBPR) were employed to triangulate multiple stakeholders' perceptions of facilitators and barriers of implementing the adapted intervention in community settings. Community partners provided an insider perspective to overcome methodological challenges...
December 24, 2016: Evaluation and Program Planning
https://www.readbyqxmd.com/read/28343010/structural-and-dynamics-studies-of-the-tetr-family-protein-cprb-from-streptomyces-coelicolor-in-complex-with-its-biological-operator-sequence
#7
Hussain Bhukya, Asis K Jana, Neelanjana Sengupta, Ruchi Anand
In Streptomycetes, tetracycline repressor family of transcription regulators (TetR-FTRs) controls various biological processes including antibiotic biosynthesis, cellular morphology and innate resistance. Here, we focus on understanding the structural basis of transcription regulation by CprB, a member of TetR-FTRs from S. coelicolor. CprB is implicated as a receptor of γ-butyrolactones, a class of quorum sensing molecules, responsible for initiating secondary metabolic pathways. In order to understand the molecular mechanism of DNA recognition, the X-ray structure of CprB in complex with its biological relevant operator sequence was solved to a resolution of 3...
March 22, 2017: Journal of Structural Biology
https://www.readbyqxmd.com/read/28342935/interpreting-patient-reported-urinary-and-sexual-function-outcomes-across-multiple-validated-instruments
#8
Emily A Vertosick, Andrew J Vickers, Janet E Cowan, Jeanette M Broering, Peter R Carroll, Matthew R Cooperberg
INTRODUCTION: Comparing patient-reported outcomes such as urinary and erectile function across institutions is critical for prostate cancer research and quality assurance. Such comparisons are complicated by the use of different questionnaires. We aimed to develop a method to convert scores between four commonly used instruments. MATERIALS AND METHODS: Patient-reported data on urinary and sexual function were collected from 1,284 men with localized prostate cancer using the Expanded Prostate Index Composite (EPIC-26), UCLA Prostate Cancer Index (PCI), Sexual Health Inventory for Men (SHIM) and International Prostate Symptom Scale (IPSS) questionnaires...
March 22, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28342805/phosphoethanolamine-addition-to-the-heptose-i-of-the-lipopolysaccharide-modifies-the-inner-core-structure-and-has-an-impact-on-the-binding-of-polymyxin-b-to-the-escherichia-coli-outer-membrane
#9
Javier Salazar, Mackarenna Alarcon, Jaime Huerta, Belén Navarro, Daniel Aguayo
Phosphoethanolamine (pEtN) decoration of E. coli Lipopolysaccharide (LPS) provides resistance to the antimicrobial Polymyxin B (PolB). While EptA and EptB enzymes catalyze the addition of pEtN to the Lipid A and Kdo (pEtN-Kdo-Lipid A), EptC catalyzes the pEtN addition to the Heptose I (pEtN-HeptI). In this study, we investigated the contribution of pEtN-HeptI to PolB resistance using eptA/eptB and eptC deficient E. coli K12 and its wild-type parent strains. These mutations were shown to decrease the antimicrobial activity of PolB on cells grown under pEtN-addition inducing conditions...
March 22, 2017: Archives of Biochemistry and Biophysics
https://www.readbyqxmd.com/read/28342722/the-effects-of-graft-size-and-insertion-site-location-during-anterior-cruciate-ligament-reconstruction-on-intercondylar-notch-impingement
#10
Alexander D Orsi, Paul K Canavan, Askhan Vaziri, Ruben Goebel, Onaly A Kapasi, Hamid Nayeb-Hashemi
BACKGROUND: Intercondylar notch impingement is detrimental to the anterior cruciate ligament (ACL). Notchplasty is a preventative remodeling procedure performed on the intercondylar notch during ACL reconstruction (ACLR). This study investigates how ACL graft geometry and both tibial and femoral insertion site location may affect ACL-intercondylar notch interactions post ACLR. A range of ACL graft sizes are reported during ACLR, from six millimeters to 11mm in diameter. Variability of three millimeters in ACL insertion site location is reported during ACLR...
March 22, 2017: Knee
https://www.readbyqxmd.com/read/28342701/predictive-subtle-or-overlooked-initial-head-ct-findings-in-patients-who-develop-delayed-chronic-subdural-hematoma
#11
William C Olivero, Huan Wang, Arash Farahvar, Thomas A Kim, Fei Wang
With the aging population, the incidence of chronic subdural hematoma (CSDH) is expected to rise. Once symptomatic the morbidity from CSDH is not insignificant. We studied patients who had a minor head injury and CT brain scan prior to developing CSDH to determine if there were any predictors on these scans for subsequent development of a CSDH. A retrospective review was performed on all patients operated for CSDH over a 3-year period and a review performed on those who had imaging studies at the time of a preceding minor head injury...
March 22, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28342631/systematic-review-impact-of-the-new-task-force-criteria-in-the-diagnosis-of-arrhythmogenic-right-ventricular-cardiomyopathy
#12
Giuseppe Femia, Raymond W Sy, Rajesh Puranik
BACKGROUND: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited disorder of cardiac desmosomes associated with ventricular arrhythmias and sudden cardiac death. The clinical diagnosis is problematic and relies on a complex criteria composed of clinical and non-clinical parameters. In 2010, the original 1994 Task Force Criteria (TFC) was revised with particular attention given to the imaging parameters. METHODS: Five retrospective studies compared the diagnostic concordance between the 1994 and 2010 TFC...
March 19, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28342337/nice-guys-homozygocity-for-the-tph2-703g-t-rs4570625-minor-allele-promotes-low-aggressiveness-and-low-anxiety
#13
Kariina Laas, Evelyn Kiive, Jarek Mäestu, Mariliis Vaht, Toomas Veidebaum, Jaanus Harro
BACKGROUND: Tryptophan hydroxylase (TPH) is the rate-limiting enzyme in the synthesis of serotonin. We examined whether the TPH2 polymorphism -703G/T (rs4570625) is associated with aggressiveness and impulsivity, and the prevalence of psychiatric disorders, in a population-representative sample. METHODS: We used self and proxy reports on aggressive behaviour in the younger birth cohort of the longitudinal Estonian Children Personality, Behaviour and Health Study collected at age 25, and earlier collected impulsivity and related data of both ECPBHS cohorts...
March 19, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28340422/the-clinicopathologic-relevance-of-reck-gene-polymorphisms-in-ameloblastoma
#14
Xudong Zhang, Jie Wang, Huijuan Liu, Yanning Zhang, Fusheng Dong
OBJECTIVE: To investigate the relationship between RECK gene polymorphisms and the clinicopathologic features of ameloblastoma. DESIGN: Normal gingival mucosa specimens were obtained from 10 healthy volunteers. Ameloblastomas were surgically removed from 30 patients and part of the tumor specimens were used to detect RECK gene polymorphisms by using PCR-single-strand conformation polymorphism (PCR-SSCP) and DNA sequencing analysis. Expression of RECK and MMP-9 protein was measured using western blot...
March 16, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28340298/quantum-yield-of-nitrite-from-the-photolysis-of-aqueous-nitrate-above-300-nm
#15
Katherine Beem Benedict, Alexander S McFall, Cort Anastasio
Photolysis of nitrate (NO3(-)) produces reactive nitrogen and oxygen species via three different channels, forming: (1) nitrogen dioxide (NO2) and hydroxyl radical ((•)OH), (2) nitrite (NO2(-)) and oxygen atom (O((3)P)), and (3) peroxynitrite (ONOO(-)). These photoproducts are important oxidants and reactants in surface waters, atmospheric drops, and snowpacks. While the efficiency of the first channel, to form NO2, is well documented, a large range of values have been reported for the second channel, nitrite, above 300 nm...
March 24, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28340242/insertion-of-miniaturized-cardiac-monitors-outside-the-catheter-operating-room-experience-and-practical-advice
#16
Jan Steffel, David Jay Wright, Harald Schäfer, Tabinda Rashid-Fadel, Thorsten Lewalter
Minor surgical procedures are increasingly being performed as outpatient procedures in settings outside hospital operating rooms (ORs). In electrophysiology, the recent miniaturization of insertable cardiac monitors (ICMs) has enabled the routine insertion of the device as a minimally invasive procedure without the need of a catheter OR. However, a shift to office-based environments for minor surgical procedures is associated with some concerns, particularly with respect to patient- and procedure-related safety in the new setting...
March 17, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28340204/changes-in-pain-and-muscle-architecture-in-colon-cancer-survivors-after-a-lumbopelvic-exercise-program-a-secondary-analysis-of-a-randomized-controlled-trial
#17
Irene Cantarero-Villanueva, Antonio I Cuesta-Vargas, Mario Lozano-Lozano, Carolina Fernández-Lao, Antonio Fernández-Pérez, Noelia Galiano-Castillo
Objective.:  To investigate the efficacy of an eight-week lumbopelvic stabilization program (CO-CUIDATE) for colon cancer survivors. Design.:  A secondary analysis of a randomized controlled clinical trial. Settings.:  A blinded, trained researcher performed the end point assessments for pain (Pressure Pain Threshold and Brief Pain Inventory) and muscle architecture (ultrasound imaging measurements). Subjects.:  Forty-six colon cancer survivors who were assigned to the CO-CUIDATE group or usual care group...
March 6, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28340195/nicotine-sales-to-minors-store-level-comparison-of-e-cigarette-vs-cigarette-violation-rates
#18
Arnold H Levinson
Introduction.: In recent years, e-cigarettes overtook cigarettes as the leading tobacco product used by U.S. adolescents. Most states, as well as federal regulations, have added e-cigarettes to laws prohibiting tobacco products sales to minors. We tested compliance with the newer regulation among Colorado urban retail businesses, speculating that violations might be more common for e-cigarettes than smokable cigarettes. Methods.: Supervised minors visited a random sample of urban businesses and sequentially attempted to purchase an e-cigarette product and cigarettes...
March 15, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28340101/dietary-assessment-in-minority-ethnic-groups-a-systematic-review-of-instruments-for-portion-size-estimation-in-the-united-kingdom
#19
Eva Almiron-Roig, Amanda Aitken, Catherine Galloway, Basma Ellahi
Dietary assessment in minority ethnic groups is critical for surveillance programs and for implementing effective interventions. A major challenge is the accurate estimation of portion sizes for traditional foods and dishes. : The aim of this systematic review was to assess records published up to 2014 describing a portion-size estimation element (PSEE) applicable to the dietary assessment of UK-residing ethnic minorities. : Electronic databases, internet sites, and theses repositories were searched, generating 5683 titles, from which 57 eligible full-text records were reviewed...
March 14, 2017: Nutrition Reviews
https://www.readbyqxmd.com/read/28340063/conventional-simplicity-iii-and-cooled-sinergy-radiofrequency-for-sacroiliac-joint-denervation-one-year-retrospective-study-comparing-two-devices
#20
Andrea Tinnirello, Sandra Barbieri, Manuel Todeschini, Maurizio Marchesini
Objective. : To compare two radiofrequency (RF) devices, Simplicity III (conventional RF), and SInergy (cooled RF), which are specifically designed to denervate the sacroiliac joint (SIJ). Design. : Retrospective observational study. Setting. : Italian National Health Service Public Hospital. Subjects.:  Forty-three patients with SIJ-derived pain refractory to conservative treatment; 21 and 22 patients, respectively, received Simplicity III or SInergy to denervate the SIJ...
March 15, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
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