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Amnesia

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https://www.readbyqxmd.com/read/29350572/semantic-language-deficit-developing-following-herpes-simplex-encephalitis-reorganization-cannibalising-language-centers
#1
Simone Mangelsdorf, Wendy Kelso, Dennis Velakoulis, Mark Walterfang
Herpes simplex virus encephalitis (HSVE) commonly presents with severe amnesia due to virus-mediated destruction of key regions in the temporal lobes, although language and executive impairment has been described. Little is known however of the long-term cognitive changes in these patients, including changes that may happen with cortical reorganization. We describe a patient with HSVE who presented with a highly unusual late-onset language syndrome, which may reflect distal cortical changes after her original injury...
January 19, 2018: Neurocase
https://www.readbyqxmd.com/read/29346236/a-teenager-with-acute-anterograde-amnesia
#2
Jennifer A Hoffmann, Michael P Goldman, Richard G Bachur
Isolated amnesia is an uncommon presenting complaint in the pediatric age group. We report the case of an 18-year-old woman who presented with the acute onset of memory difficulty and an otherwise normal neurologic examination. Brain magnetic resonance imaging demonstrated inflammation in the bilateral temporal lobes. Serum and cerebrospinal fluid testing ultimately revealed a diagnosis of autoimmune encephalitis. Although rare, the acute onset of isolated amnesia deserves a prompt, comprehensive evaluation...
January 16, 2018: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29337721/continuing-play-symptom-severity-and-symptom-duration-after-concussion-in-youth-athletes
#3
David R Howell, Michael J OʼBrien, Joana Fraser, William P Meehan
OBJECTIVE: To determine whether continuing to play after a concussion is associated with higher symptom burden or prolonged symptom duration. DESIGN: Patients who presented for care at a sport concussion clinic within the first 3 weeks of injury were asked whether they continued to play immediately after their injury. SETTING: Sport concussion clinic within a regional tertiary care hospital. MAIN OUTCOME MEASURES: Clinical outcomes including symptom severity, symptom duration, age, time from injury-clinical presentation, sex, sport type, previous concussion history, and whether or not they experienced loss of consciousness or amnesia at the time of injury were recorded...
January 15, 2018: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/29334804/characterizing-on-road-driving-performance-in-individuals-with-traumatic-brain-injury-who-pass-or-fail-an-on-road-driving-assessment
#4
Renerus J Stolwyk, Judith L Charlton, Pamela E Ross, Michel Bédard, Shawn Marshall, Sylvain Gagnon, James R Gooden, Jennie L Ponsford
OBJECTIVE: To characterise on-road driving performance in individuals with traumatic brain injury who fail on-road driving assessment, compared with both those who pass assessment and healthy controls, and the injury and cognitive factors associated with driving performance. STUDY DESIGN: Cross-sectional. METHODS: Forty eight participants with traumatic brain injury (Age M = 40.50 SD = 14.62, 77% male, post-traumatic amnesia days M = 28...
January 15, 2018: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29334662/aqueous-extracts-of-two-tropical-ethnobotanicals-tetrapleura-tetraptera-and-quassia-undulata-improved-spatial-and-non-spatial-working-memories-in-scopolamine-induced-amnesic-rats-influence-of-neuronal-cholinergic-and-antioxidant-systems
#5
Veronica O Odubanjo, Emmanuel O Ibukun, Ganiyu Oboh, Stephen A Adefegha
BACKGROUND: Tetrapleura tetraptera (TT) and Quassia undulata (QU) are two predominant tropical ethnobotanicals with various medicinal values but are commonly used in folklore for the treatment of mental illness without justifiable mechanisms of action. AIM OF THE STUDY: To investigate the effects of aqueous extracts from TT fruits and QU leaves on the spatial and non-spatial working memory, antioxidant status and activities of neuronal marker enzymes of scopolamine-induced amnesic rats and thus, understand the possible mechanism of action of these plants...
January 11, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29331203/have-we-forgotten-about-forgetting-a-critical-review-of-accelerated-long-term-forgetting-in-temporal-lobe-epilepsy
#6
REVIEW
Anneli Cassel, Michael D Kopelman
Forgetting has been researched for over a century. This literature highlighted how forgetting rates can vary dependent on factors in the design and method. Recent interest in forgetting revived with evidence suggesting that seizures experienced almost immediately after matched learning could accelerate forgetting. This was followed by a growth in forgetting studies in patients with temporal lobe epilepsy (TLE), including a subset of those with transient epileptic amnesia (TEA). These patients have been described as expressing concerns about memory, yet often perform within 'normal' ranges on standard neuropsychological memory assessments...
December 26, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/29330003/effects-of-5-ht5a-receptor-blockade-on-amnesia-or-forgetting
#7
L Aparicio-Nava, L A Márquez-García, A Meneses
Previously the effects (0.01-3.0 mg/kg) of post-training SB-699551 (a 5-HT5A receptor antagonist) were reported in the associative learning task of autoshaping, showing that SB-699551 (0.1 mg/kg) decreased lever-press conditioned responses (CR) during short-term (STM; 1.5-h) or (3.0 mg/kg) long-term memory (LTM; 24-h); relative to the vehicle animals. Moreover, as pro-cognitive efficacy of SB-699551 was reported in the ketamine-model of schizophrenia. Hence, firstly aiming improving performance (conditioned response, CR), in this work autoshaping lever-press vs...
January 9, 2018: Behavioural Brain Research
https://www.readbyqxmd.com/read/29329640/capturing-real-life-forgetting-in-transient-epileptic-amnesia-via-an-incidental-memory-test
#8
Serge Hoefeijzers, Adam Zeman, Sergio Della Sala, Michaela Dewar
Transient epileptic amnesia (TEA) is an epileptic syndrome characterized by recurrent, brief episodes of amnesia. Patients with TEA often complain of interictal (between attacks) retention deficits, characterised by an 'evaporation' of memories for recent events over days to weeks. Clinical tests of anterograde memory often fail to corroborate these complaints as TEA patients commonly perform within the normal range after the standard 10-30-min delay period. Modified laboratory tests that include a 1-3 week delay period frequently reveal clear evidence of 'accelerated long-term forgetting' (ALF)...
December 13, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/29318929/the-pharmacogenetics-of-medications-used-in-general-anesthesia
#9
Shangchen Xie, Wenjuan Ma, Qulian Guo, Jie Liu, Wei Li, Howard L McLeod, Yijing He
General anesthesia is a state of unconsciousness, amnesia, analgesia and akinesia induced by drugs including opioids, hypnotic-sedative agents, muscle relaxants and antiemetics. Clinical and genetic factors are reported to influence the efficacy and side effects of these agents. Based on the evidence, clinical action is needed to improve clinical outcomes. This review summarizes the latest knowledge with regards to the pharmacogenetics of anesthetics and general anesthesia related complications.
January 10, 2018: Pharmacogenomics
https://www.readbyqxmd.com/read/29302772/development-and-preliminary-psychometric-properties-of-an-instrument-for-the-measurement-of-obsessional-dissociative-experiences-the-van-obsessional-dissociation-questionnaire-vod-q
#10
Murat Boysan, Abdullah Yıldırım, Lütfullah Beşiroğlu, Mehmet Celal Kefeli, Mücahit Kağan
A growing body of research evidence documents the substantial associations between obsessive-compulsive disorder (OCD) and dissociation. This article describes the development and preliminary psychometric properties of the Van Obsessional Dissociation Questionnaire (VOD-Q). Obsessional dissociation is defined as a tendency to dissociate in reaction to distressing, unwanted and intrusive thoughts, images and impulses. The screening tool is conceptualized to tap obsessional dissociation across three dimensions: obsessional absorption, obsessional depersonalization/ derealization and obsessional amnesia...
January 4, 2018: Psychiatric Quarterly
https://www.readbyqxmd.com/read/29299390/cortical-morphology-in-patients-with-transient-global-amnesia
#11
Hyung Chan Kim, Byung In Lee, Sung Eun Kim, Kang Min Park
Objective: This study evaluated alterations in cortical morphology in patients with transient global amnesia (TGA). Materials and Methods: Diagnoses of TGA occurred at our hospital. Evaluation involved a structured interview to obtain clinical information and a brain magnetic resonance imaging scan. We analyzed whole-brain T1-weighted MRI data using FreeSurfer 5.1. Measures of cortical morphology, such as thickness, surface area, volume, and curvature were compared between patients with TGA and healthy controls...
December 2017: Brain and Behavior
https://www.readbyqxmd.com/read/29296086/brain-functional-integration-an-epidemiologic-study-on-stress-producing-dissociative-phenomena
#12
Raffaele Sperandeo, Vincenzo Monda, Giovanni Messina, Marco Carotenuto, Nelson Mauro Maldonato, Enrico Moretto, Elena Leone, Vincenzo De Luca, Marcellino Monda, Antonietta Messina
Dissociative phenomena are common among psychiatric patients; the presence of these symptoms can worsen the prognosis, increasing the severity of their clinical conditions and exposing them to increased risk of suicidal behavior. Personality disorders as long duration stressful experiences may support the development of dissociative phenomena. In 933 psychiatric outpatients consecutively recruited, presence of dissociative phenomena was identified with the Dissociative Experience Scale (DES). Dissociative phenomena were significantly more severe in the group of people with mental disorders and/or personality disorders...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29284863/evaluation-of-effectiveness-of-dexmedetomidine-and-fentanyl-midazolam-combination-on-sedation-and-safety-during-awake-fiberoptic-intubation-a-randomized-comparative-study
#13
Abida Yousuf, Basharat Ahad, Aabid Hussain Mir, Abdul Waheed Mir, Juvera Gul Wani, Sheikh Quyoom Hussain
Background: Awake fiberoptic intubation (AFOI) is a recommended technique for anticipated difficult airway. An ideal regime should provide patient comfort, cooperation, amnesia, hemodynamic stability, and blunt airway reflexes and maintain a patent airway with spontaneous ventilation. The aim of our study was to compare intubation conditions between dexmedetomidine and fentanyl-midazolam combination during AFOI. Methods: This prospective, randomized study was conducted on a total of sixty patients of the American Society of Anesthesiologists physical status I and II of either sex, in the age group of 18-60 years having predicted difficult intubation undergoing elective surgeries and the patients were allocated to two groups of thirty patients each...
October 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/29280675/the-political-biography-of-an-earthquake-aftermath-and-amnesia-in-gujarat-india
#14
James Smith
No abstract text is available yet for this article.
December 27, 2017: Medicine, Conflict, and Survival
https://www.readbyqxmd.com/read/29277588/sport-related-traumatic-brain-injury-with-and-without-helmets-in-children
#15
Angela Bandte, Friederike-Sophie Fritzsche, Pedram Emami, Getrud Kammler, Klaus Püschel, Kara Krajewski
BACKGROUND: Soccer, bicycling and horseback riding are sports most commonly associated with traumatic brain injury (TBI) in Germany. The latter are commonly practiced with helmets and data on helmet use and usefulness vary widely. METHODS: After ethics approval, retrospective analysis was performed for patients ages 5-17 from 01/2009- 08/2014 based on the diagnosis TBI using the electronic patient file for both university hospital locations. Descriptive data analysis, multi- and univariate logistic regression were employed to calculate the odds ratio...
December 22, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29276489/multi-protection-of-dl0410-in-ameliorating-cognitive-defects-in-d-galactose-induced-aging-mice
#16
Wenwen Lian, Hao Jia, Lvjie Xu, Wei Zhou, De Kang, Ailin Liu, Guanhua Du
D-galactose has been reported to accelerate senescence in rodents, accompanied by a decline in learning and memory. We used a model of D-galactose-induced amnesia for the efficacy evaluation and pharmacologic studies of active compounds against Alzheimer's disease (AD). DL0410 is a potent inhibitor against acetylcholinesterase (AChE) and, in the present study, the effect of DL0410 was evaluated in this model. We found that DL0410 could significantly improve the learning and memory of D-galactose induced aging mice in a series of behavioral tests: novel-object recognition test, nest-building test, Morris water maze test and step-through test...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/29260547/cognitive-improving-effects-by-highbush-blueberry-vaccinium-crymbosum-l-vinegar-on-scopolamine-induced-amnesia-mice-model
#17
Seong Min Hong, Kyong Hee Soe, Taek Hwan Lee, In Sook Kim, Young Min Lee, Beong Ou Lim
The present study aimed to evaluate the preventive effects of highbush blueberry (Vaccinium corymbosum L.) vinegar (BV) on cognitive functions in a scopolamine (Sco)-induced amnesia model in mice. In this study, Sco (1 mg/kg, intraperitoneal injection) was used to induce amnesia. ICR mice were orally administered donepezil (5 mg/kg), blueberry extract (120 mg/kg), and BV (120 mg/kg) for 7 days. After inducing cognitive impairment by Sco, a behavioral assessment using behavior tests (i.e., Y-maze and passive avoidance tests) was performed...
December 20, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29240569/paediatric-procedural-sedation-and-analgesia-by-emergency-physicians-in-a-country-with-a-recent-establishment-of-emergency-medicine
#18
Maybritt I Kuypers, Gaël J P Smits, Eva P Baerends, Erick Oskam, Eef P J Reijners, Lisette A A Mignot-Evers, Wendy A M H Thijssen, Frans B Plötz, Erik H M Korsten
OBJECTIVES: Paediatric patients receive less procedural sedation and analgesia (PSA) in the emergency department compared with adults, especially in countries where emergency medicine is at an early stage of development. The objectives of this study were to evaluate the adverse events and efficacy of paediatric PSA in a country with a recent establishment of emergency medicine and to describe which factors aided implementation. METHODS: This is a prospective, multicentre, observational study of paediatric patients undergoing PSA by the first trained emergency physicians (EPs) in The Netherlands...
December 13, 2017: European Journal of Emergency Medicine: Official Journal of the European Society for Emergency Medicine
https://www.readbyqxmd.com/read/29240021/differences-in-seizure-expression-between-magnetic-seizure-therapy-and-electroconvulsive-shock
#19
Yael M Cycowicz, Stefan B Rowny, Bruce Luber, Sarah H Lisanby
OBJECTIVE: Evidence suggests that magnetic seizure therapy (MST) results in fewer side effects than electroconvulsive treatment, both in humans treated with electroconvulsive therapy (ECT) as well as in the animal preclinical model that uses electroconvulsive shock (ECS). Evidence suggests that MST results in fewer cognitive side effects than ECT. Although MST offers enhanced control over seizure induction and spread, little is known about how MST and ECT seizures differ. Seizure characteristics are associated with treatment effect...
December 12, 2017: Journal of ECT
https://www.readbyqxmd.com/read/29233056/looking-at-the-past-through-a-telescope-adults-postdated-their-earliest-childhood-memories
#20
Qi Wang, Carole Peterson, Angel Khuu, Carissa P Reid, Kayleigh L Maxwell, Julia M Vincent
Our previous studies have consistently shown a telescoping error in children's dating of earliest childhood memories. Preschool children through adolescents systematically date their earliest memories at older ages, in comparison with the age estimates provided by their parents or by themselves previously. In the current study, we examined the dating of earliest childhood memories in two samples of college adults and collected independent age estimates from their parents. Consistent with our findings with children, adults significantly postdated their earlier memories by approximately 12 months (Study 1) and 6 months (Study 2)...
December 13, 2017: Memory
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