keyword
MENU ▼
Read by QxMD icon Read
search

igrt

keyword
https://www.readbyqxmd.com/read/29663429/remote-cherenkov-imaging-based-quality-assurance-of-a-magnetic-resonance-image-guided-radiotherapy-system
#1
Jacqueline M Andreozzi, Karen E Mooney, Petr Brůža, Austen Curcuru, David J Gladstone, Brian W Pogue, Olga Green
PURPOSE: Tools to perform regular quality assurance of magnetic resonance image-guided radiotherapy (MR-IGRT) systems should ideally be independent of interference from the magnetic fields. Remotely acquired optical Cherenkov imaging-based dosimetry measurements in water were investigated for this purpose, comparing measures of dose accuracy, temporal dynamics, and overall integrated IMRT delivery. METHODS: A 40x30.5x37.5cm3 water tank doped with 1g/L of quinine sulfate was imaged using an intensified charge coupled device (ICCD) to capture the Cherenkov emission while being irradiated by a commercial MR-IGRT system (ViewRay™ )...
April 16, 2018: Medical Physics
https://www.readbyqxmd.com/read/29644723/a-french-observational-study-describing-the-use-of-human-polyvalent-immunoglobulins-in-hematological-malignancy-associated-secondary-immunodeficiency
#2
Omar Benbrahim, Jean-François Viallard, Sylvain Choquet, Bruno Royer, Frédéric Bauduer, Olivier Decaux, Jean-Charles Crave, Yann Fardini, Pierre Clerson, Vincent Levy
OBJECTIVE: To describe the characteristics of patients suffering from secondary immunodeficiencies (SID) associated with hematological malignancies (HM), who started immunoglobulins replacement therapy (IgRT), physicians' expectations regarding IgRT and IgRT modalities. METHODS: Non-interventional, prospective French cross-sectional study. RESULTS: The analysis included 231 patients (66±12 years old) suffering from multiple myeloma (MM) (N=64), chronic lymphoid leukemia (CLL) (N=84), aggressive non-Hodgkin B-cell lymphoma (aNHL) (N=32), indolent NHL (N=39), acute leukemia (N=6), Hodgkin disease (N=6)...
April 12, 2018: European Journal of Haematology
https://www.readbyqxmd.com/read/29618922/in-depth-interviews-of-patients-with-primary-immunodeficiency-who-have-experienced-pump-and-rapid-push-subcutaneous-infusions-of-immunoglobulins-reveal-new-insights-on-their-preference-and-expectations
#3
Grégoire Jacques Noël Cozon, Pierre Clerson, Annaïk Dokhan, Yann Fardini, Taylor Pindi Sala, Jean-Charles Crave
Purpose: Patients with primary immunodeficiency (PID) often receive immunoglobulin replacement therapy (IgRT). Physicians and patients have the choice between various methods of administration. For subcutaneous immunoglobulin infusions, patients may use an automated pump (P) or push the plunger of a syringe (rapid push [RP]). P infusions are performed once a week and last around 1 hour. RP decreases the duration of administration, but requires more frequent infusions. Patients and methods: Eight out of 30 patients (coming from a single center) who had participated in the cross-over, randomized, open-label trial comparing P and RP participated in a focus group or underwent in-depth interviews...
2018: Patient Preference and Adherence
https://www.readbyqxmd.com/read/29609822/a-framework-for-alignment-of-on-board-imagers-of-medical-linear-accelerators
#4
M Tulik, D Kabat, R A Kycia, Z Tabor, A Woszczyna, Z Latała
PURPOSE: To develop an assumption-free methodology for aligning the geometry of on-board imagers with the geometry of medical linear accelerators applied in image-guided radiotherapy (IGRT). MATERIAL: Alignment of the on-board imaging (OBI) system with respect to the accelerator system is achieved using a multi-modular phantom described elsewhere (Tabor et al., 2017), enabling the geometry of the linear accelerator to be specified without any pre-assumptions. METHODS: The placement of two isocentres (of the on-board imager and of the therapeutic system) and of three frames of reference (those of the on-board imager, of the therapeutic system, and of the treatment table) is formulated as an optimization problem...
March 2018: Physica Medica: PM
https://www.readbyqxmd.com/read/29594251/the-embrace-ii-study-the-outcome-and-prospect-of-two-decades-of-evolution-within-the-gec-estro-gyn-working-group-and-the-embrace-studies
#5
REVIEW
Richard Pötter, Kari Tanderup, Christian Kirisits, Astrid de Leeuw, Kathrin Kirchheiner, Remi Nout, Li Tee Tan, Christine Haie-Meder, Umesh Mahantshetty, Barbara Segedin, Peter Hoskin, Kjersti Bruheim, Bhavana Rai, Fleur Huang, Erik Van Limbergen, Max Schmid, Nicole Nesvacil, Alina Sturdza, Lars Fokdal, Nina Boje Kibsgaard Jensen, Dietmar Georg, Marianne Assenholt, Yvette Seppenwoolde, Christel Nomden, Israel Fortin, Supriya Chopra, Uulke van der Heide, Tamara Rumpold, Jacob Christian Lindegaard, Ina Jürgenliemk-Schulz
The publication of the GEC-ESTRO recommendations one decade ago was a significant step forward for reaching international consensus on adaptive target definition and dose reporting in image guided adaptive brachytherapy (IGABT) in locally advanced cervical cancer. Since then, IGABT has been spreading, particularly in Europe, North America and Asia, and the guidelines have proved their broad acceptance and applicability in clinical practice. However, a unified approach to volume contouring and reporting does not imply a unified administration of treatment, and currently both external beam radiotherapy (EBRT) and IGABT are delivered using a large variety of techniques and prescription/fractionation schedules...
February 2018: Clinical and translational radiation oncology
https://www.readbyqxmd.com/read/29594230/local-control-and-overall-survival-after-frameless-radiosurgery-a-single-center-experience
#6
Angelika Bilger, Florian Frenzel, Oliver Oehlke, Rolf Wiehle, Dusan Milanovic, Vesna Prokic, Carsten Nieder, Anca-Ligia Grosu
Introduction: Stereotactic radiosurgery (SRS) has been increasingly advocated for 1-3 small brain metastases. The goal of this study was to evaluate the clinical results in patients with brain metastases treated with LINAC-based SRS using a thermoplastic mask (non-invasive fixation system) and Image-Guided Radiotherapy (IGRT). Material and Methods: In this single-institution study 48 patients with 77 brain metastases were treated between February 2012 and January 2014...
December 2017: Clinical and Translational Radiation Oncology
https://www.readbyqxmd.com/read/29594038/priming-the-abscopal-effect-using-multifunctional-smart-radiotherapy-biomaterials-loaded-with-immunoadjuvants
#7
Michele Moreau, Sayeda Yasmin-Karim, Sijumon Kunjachan, Neeharika Sinha, Felix Gremse, Rajiv Kumar, Kwok Fan Chow, Wilfred Ngwa
In this study, we investigate the use of multifunctional smart radiotherapy biomaterials (SRBs) loaded with immunoadjuvants for boosting the abscopal effect of local radiotherapy (RT). SRBs were designed similar to currently used inert RT biomaterials, incorporating a biodegradable polymer with reservoir for loading payloads of the immunoadjuvant anti-CD40 monoclonal antibody. Lung (LLC1) tumors were generated both on the right and left flank of each mouse, with the left tumor representing metastasis. The mice were randomized and divided into eight cohorts with four cohorts receiving image-guided RT (IGRT) at 5 Gy and another similar four cohorts at 0 Gy...
2018: Frontiers in Oncology
https://www.readbyqxmd.com/read/29573744/optimization-of-treatment-planning-workflow-and-tumor-coverage-during-daily-adaptive-magnetic-resonance-image-guided-radiation-therapy-mr-igrt-of-pancreatic-cancer
#8
Sven Olberg, Olga Green, Bin Cai, Deshan Yang, Vivian Rodriguez, Hao Zhang, Jin Sung Kim, Parag J Parikh, Sasa Mutic, Justin C Park
BACKGROUND: To simplify the adaptive treatment planning workflow while achieving the optimal tumor-dose coverage in pancreatic cancer patients undergoing daily adaptive magnetic resonance image guided radiation therapy (MR-IGRT). METHODS: In daily adaptive MR-IGRT, the plan objective function constructed during simulation is used for plan re-optimization throughout the course of treatment. In this study, we have constructed the initial objective functions using two methods for 16 pancreatic cancer patients treated with the ViewRay™ MR-IGRT system: 1) the conventional method that handles the stomach, duodenum, small bowel, and large bowel as separate organs at risk (OARs) and 2) the OAR grouping method...
March 24, 2018: Radiation Oncology
https://www.readbyqxmd.com/read/29562919/comparison-of-carina-based-versus-bony-anatomy-based-registration-for-setup-verification-in-esophageal-cancer-radiotherapy
#9
Mélanie Machiels, Peng Jin, Christianne H van Gurp, Jeanin E van Hooft, Tanja Alderliesten, Maarten C C M Hulshof
BACKGROUND: To investigate the feasibility and geometric accuracy of carina-based registration for CBCT-guided setup verification in esophageal cancer IGRT, compared with current practice bony anatomy-based registration. METHODS: Included were 24 esophageal cancer patients with 65 implanted fiducial markers, visible on planning CTs and follow-up CBCTs. All available CBCT scans (n = 236) were rigidly registered to the planning CT with respect to the bony anatomy and the carina...
March 21, 2018: Radiation Oncology
https://www.readbyqxmd.com/read/29556580/salvage-image-guided-radiation-therapy-to-the-prostate-after-cryotherapy-failure
#10
Austin B Hopper, Ajay P S Sandhu, J Kellogg Parsons, Brent Rose, John P Einck
Purpose: Cryotherapy is an option for the primary treatment of localized prostate cancer, along with radical prostatectomy, external beam radiation therapy, and brachytherapy. Although it is known that local recurrence can occur in >20% of patients treated with primary cryotherapy, unfortunately there is a paucity of data on later salvage treatments. The use of external beam radiation therapy is an attractive option after cryotherapy failure, but there is little data on its efficacy and toxicity...
January 2018: Advances in Radiation Oncology
https://www.readbyqxmd.com/read/29556317/tumor-bed-radiotherapy-in-women-following-breast-conserving-surgery-for-breast-cancer-safety-margin-with-without-image-guidance
#11
Ales Hlavka, Jaroslav Vanasek, Karel Odrazka, Jan Stuk, Martin Dolezel, Vit Ulrych, Martina Vitkova, Jiri Mynarik, Iveta Kolarova, Zdenka Vilasova
Image guided radiation therapy (IGRT) enables the achievement of higher precision in radiation delivery, a reduction in safety margins and a reduced risk of toxicity in healthy tissues. The present study investigated the magnitude of safety margins for the radiation boost setup on skin marks or metal clips implanted into the tumor bed during breast cancer surgery. One hundred eighty-four patients after breast conserving surgery with implanted metal clips into tumor bed were analyzed. The present study investigated the difference in safety margin required for the treatment setup on skin marks and metal clips...
April 2018: Oncology Letters
https://www.readbyqxmd.com/read/29532493/image-guided-radiotherapy-quality-control-statistical-process-control-using-image-similarity-metrics
#12
Satomi Shiraishi, Michael P Grams, Luis E Fong de Los Santos
PURPOSE: To demonstrate an objective quality control framework for the image review process. METHODS AND MATERIALS: 927 cone-beam computed tomography (CBCT) registrations were retrospectively analyzed for 33 bilateral head and neck cancer patients who received definitive radiotherapy. Two registration tracking volumes (RTVs) - cervical spine (C-spine) and mandible - were defined, within which a similarity metric was calculated and used as a registration quality tracking metric over the course of treatment...
March 12, 2018: Medical Physics
https://www.readbyqxmd.com/read/29520019/hypofractionated-simultaneous-integrated-boost-imrt-sib-with-pelvic-nodal-irradiation-and-concurrent-androgen-deprivation-therapy-for-high-risk-prostate-cancer-results-of-a-prospective-phase-ii-trial
#13
Alessandro Magli, Eugenia Moretti, Annarita Tullio, Gianluca Giannarini, Fabrizio Tonetto, Mauro Urpis, Margherita Crespi, Claudio Foti, Agnese Prisco, Margherita Polsinelli, Gioacchino De Giorgi, Giulia Bravo, Paolo Scalchi, Marco Trovò
OBJECTIVE: The approach for treating high-risk prostate cancer still presents different unresolved issues. We report the safety and efficacy of a radiation therapy strategy based on the combination of moderate hypofractioned simultaneous integrated boost (SIB) and Image Guidance. MATERIALS AND METHODS: In this phase II trial of patients with high-risk prostate cancer, Image Guided SIB-IMRT plans (Simultaneous Intensity Modulated - Intensity Modulated Radiotherapy) were delivered between 2009 and 2012...
March 8, 2018: Prostate Cancer and Prostatic Diseases
https://www.readbyqxmd.com/read/29519410/cone-beam-ct-based-inter-fraction-localization-errors-for-tumors-in-the-pelvic-region
#14
Cristina Garibaldi, Cristiana Fodor, Giulia Riva, Damaris Patricia Rojas, Samantha Dicuonzo, Elisa Pace, Giuseppe Fanetti, Paolo De Marco, Veronica Dell'acqua, Giulia Marvaso, Maria Cristina Leonardi, Roberta Lazzari, Federica Cattani, Marta Cremonesi, Roberto Orecchia, Barbara Alicja Jereczek-Fossa
PURPOSE: To evaluate inter-fraction tumor localization errors (TE) in the RapidArc® treatment of pelvic cancers based on CBCT. Appropriate CTV-to PTV margins in a non-IGRT scenario have been proposed. METHODS: Data of 928 patients with prostate, gynecological, and rectum/anal canal cancers were retrospectively analyzed to determine systematic and random localization errors. Two protocols were used: daily online IGRT (d-IGRT) and weekly IGRT. The latter consisted in acquiring a CBCT for the first 3 fractions and subsequently once a week...
February 2018: Physica Medica: PM
https://www.readbyqxmd.com/read/29516610/optimizing-the-target-detectability-of-cone-beam-ct-performed-in-image-guided-radiation-therapy-for-patients-of-different-body-sizes
#15
Ching-Ching Yang, Pei-Chieh Yu, Jau-Ming Ruan, Yu-Cheng Chen
PURPOSE: The target detectability of cone beam computed tomography (CBCT) performed in image-guided radiation therapy (IGRT) was investigated to achieve sufficient image quality for patient positioning over a course of treatment session while maintaining radiation exposure from CBCT imaging as low as reasonably achievable (ALARA). METHODS: Body CBCT scans operated in half-fan mode were acquired with three different protocols: CBCTlowD , CBCTmidD , and CBCThighD , which resulted in weighted CT dose index (CTDIw ) of 0...
March 8, 2018: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/29500856/normal-tissue-doses-from-mv-image-guided-radiation-therapy-igrt-using-orthogonal-mv-and-mv-cbct
#16
Yuting Li, Tucker Netherton, Paige L Nitsch, Peter A Balter, Song Gao, Ann H Klopp, Laurence E Court
PURPOSE: The aim of this study was to measure and compare the mega-voltage imaging dose from the Halcyon medical linear accelerator (Varian Medical Systems) with measured imaging doses with the dose calculated by Eclipse treatment planning system. METHODS: An anthropomorphic thorax phantom was imaged using all imaging techniques available with the Halcyon linac - MV cone-beam computed tomography (MV-CBCT) and orthogonal anterior-posterior/lateral pairs (MV-MV), both with high-quality and low-dose modes...
March 3, 2018: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/29468678/image-guidance-doses-delivered-during-radiotherapy-quantification-management-and-reduction-report-of-the-aapm-therapy-physics-committee-task-group-180
#17
George X Ding, Parham Alaei, Bruce Curran, Ryan Flynn, Michael Gossman, T Rock Mackie, Moyed Miften, Richard Morin, X George Xu, Timothy C Zhu
With radiotherapy having entered the era of image guidance, or image-guided radiation therapy (IGRT), imaging procedures are routinely performed for patient positioning and target localization. The imaging dose delivered may result in excessive dose to sensitive organs and potentially increase the chance of secondary cancers and, therefore, needs to be managed. This task group was charged with: a) providing an overview on imaging dose, including megavoltage electronic portal imaging (MV EPI), kilovoltage digital radiography (kV DR), Tomotherapy MV-CT, megavoltage cone-beam CT (MV-CBCT) and kilovoltage cone-beam CT (kV-CBCT), and b) providing general guidelines for commissioning dose calculation methods and managing imaging dose to patients...
February 22, 2018: Medical Physics
https://www.readbyqxmd.com/read/29463958/interfractional-diaphragm-changes-during-breath-holding-in-stereotactic-body-radiotherapy-for-liver-cancer
#18
Daisuke Kawahara, Shuichi Ozawa, Takeo Nakashima, Shintaro Tsuda, Yusuke Ochi, Takuro Okumura, Hirokazu Masuda, Kazunari Hioki, Tathsuhiko Suzuki, Yoshimi Ohno, Tomoki Kimura, Yuji Murakami, Yasushi Nagata
Aim and background: IGRT based on bone matching may produce a large target positioning error in terms of the reproducibility of expiration breath-holding on SBRT for liver cancer. We evaluated the intrafractional and interfractional errors using the diaphragm position at the end of expiration by utilising Abches and analysed the factor of the interfractional error. Materials and methods: Intrafractional and interfractional errors were measured using a couple of frontal kV images, planning computed tomography (pCT) and daily cone-beam computed tomography (CBCT)...
March 2018: Reports of Practical Oncology and Radiotherapy
https://www.readbyqxmd.com/read/29457751/intra-and-inter-fraction-uncertainties-during-igrt-for-wilms-tumor
#19
Filipa Guerreiro, Enrica Seravalli, Geert O Janssens, Cees P van de Ven, Marry M van den Heuvel-Eibrink, Bas W Raaymakers
BACKGROUND AND PURPOSE: To assess intra- and inter-fraction motion uncertainties, due to displacements of the tumor bed (TB) and organs at risk (OAR), as well as intra- and inter-fraction patient set-up uncertainties, due to positioning variations, during image-guided radiation therapy (IGRT) in children with Wilms' tumor. MATERIAL AND METHODS: Four-dimensional computed tomography (4D-CT) and daily pre- and post-treatment cone-beam CT (CBCT)-scans of 15 patients (average 4, range 1-8 years) undergoing flank irradiation after nephrectomy were analyzed...
February 19, 2018: Acta Oncologica
https://www.readbyqxmd.com/read/29453744/low-serum-ige-is-a-sensitive-and-specific-marker-for-common-variable-immunodeficiency-cvid
#20
Monica G Lawrence, Thamiris V Palacios-Kibler, Lisa J Workman, Alexander J Schuyler, John W Steinke, Spencer C Payne, Emily C McGowan, James Patrie, Ramsay L Fuleihan, Kathleen E Sullivan, Patricia L Lugar, Camellia L Hernandez, Douglas E Beakes, James W Verbsky, Thomas A E Platts-Mills, Charlotte Cunningham-Rundles, John M Routes, Larry Borish
Although small prior studies have suggested that IgE can be low in common variable immunodeficiency (CVID), the workup for patients with recurrent infections and suspected hypogammaglobulinemia does not include the routine measurement of serum IgE. We sought to test the hypothesis that low/undetectable serum IgE is characteristic of CVID by comparing the frequency of low/undetectable serum IgE in healthy controls and patients with CVID. We measured total serum IgE in a large multi-center cohort of patients with CVID (n = 354) and compared this to large population-based cohorts of children and adults...
February 17, 2018: Journal of Clinical Immunology
keyword
keyword
12351
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"