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https://www.readbyqxmd.com/read/28337425/post-prostatectomy-image-guided-radiotherapy-the-invisible-target-concept
#1
REVIEW
Florent Vilotte, Mickael Antoine, Maxime Bobin, Igor Latorzeff, Stéphane Supiot, Pierre Richaud, Laurence Thomas, Nicolas Leduc, Stephane Guérif, Jone Iriondo-Alberdi, Renaud de Crevoisier, Paul Sargos
In the era of intensity-modulated radiation therapy, image-guided radiotherapy (IGRT) appears crucial to control dose delivery and to promote dose escalation while allowing healthy tissue sparing. The place of IGRT following radical prostatectomy is poorly described in the literature. This review aims to highlight some key points on the different IGRT techniques applicable to prostatic bed radiotherapy. Furthermore, methods used to evaluate target motion and to reduce planning target volume margins will also be explored...
2017: Frontiers in Oncology
https://www.readbyqxmd.com/read/28332342/evaluation-of-the-truebeam-machine-performance-check-mpc-geometric-checks-for-daily-igrt-geometric-accuracy-quality-assurance
#2
Michael P Barnes, Peter B Greer
Machine Performance Check (MPC) is an automated and integrated image-based tool for verification of beam and geometric performance of the TrueBeam linac. The aims of the study were to evaluate the performance of the MPC geometric tests relevant to OBI/CBCT IGRT geometric accuracy. This included evaluation of the MPC isocenter and couch tests. Evaluation was performed by comparing MPC to QA tests performed routinely in the department over a 4-month period. The MPC isocenter tests were compared against an in-house developed Winston-Lutz test and the couch compared against routine mechanical QA type procedures...
March 22, 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28321456/-comparison-of-combined-imrt-and-igrt-with-conventional-3d-crt-in-the-irradiation-of-prostate-cancer-studying-the-advantages-strongly-depends-on-the-conditions
#3
Norbert Hodapp
No abstract text is available yet for this article.
March 20, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28297443/comparison-of-automatic-image-registration-uncertainty-for-three-igrt-systems-using-a-male-pelvis-phantom
#4
Jeffrey Barber, Jonathan R Sykes, Lois Holloway, David I Thwaites
A series of phantom images using the CIRS Virtual Human Male Pelvis was acquired across available dose ranges for three image-guided radiotherapy (IGRT) imaging systems: Elekta XVI CBCT, Varian TrueBeam CBCT, and TomoTherapy MV CT. Each image was registered to a fan-beam CT within the XVI software 100 times with random initial offsets. The residual registration error was analyzed to assess the role of imaging hardware and reconstruction in the uncertainty of the IGRT process. Residual translation errors were similar for all systems and <0...
September 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28297353/comparison-of-manual-and-automatic-mr-ct-registration-for-radiotherapy-of-prostate-cancer
#5
Anne Sofie Korsager, Jesper Carl, Lasse Riis Østergaard
In image-guided radiotherapy (IGRT) of prostate cancer, delineation of the clinical target volume (CTV) often relies on magnetic resonance (MR) because of its good soft-tissue visualization. Registration of MR and computed tomography (CT) is required in order to add this accurate delineation to the dose planning CT. An automatic approach for local MR-CT registration of the prostate has previously been developed using a voxel property-based registration as an alternative to a manual landmark-based registration...
May 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28297345/a-software-tool-to-automatically-assure-and-report-daily-treatment-deliveries-by-a-cobalt-60-radiation-therapy-device
#6
Deshan Yang, H Omar Wooten, Olga Green, Harold H Li, Shi Liu, Xiaoling Li, Vivian Rodriguez, Sasa Mutic, Rojano Kashani
The aims of this study were to develop a method for automatic and immediate verification of treatment delivery after each treatment fraction in order to detect and correct errors, and to develop a comprehensive daily report which includes delivery verification results, daily image-guided radiation therapy (IGRT) review, and information for weekly physics reviews. After systematically analyzing the requirements for treatment delivery verification and understanding the available information from a commercial MRI-guided radiotherapy treatment machine, we designed a procedure to use 1) treatment plan files, 2) delivery log files, and 3) beam output information to verify the accuracy and completeness of each daily treatment delivery...
May 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28297337/one-year-analysis-of-elekta-cbct-image-quality-using-nps-and-mtf
#7
Satomi Nakahara, Masayuki Tachibana, Yoichi Watanabe
The image quality (IQ) of imaging systems must be sufficiently high for image-guided radiation therapy (IGRT). Hence, users should implement a quality assurance program to maintain IQ. In our routine IQ tests of the kV cone-beam CT system (Elekta XVI), image noise was quantified by noise standard deviation (NSD), which was the standard deviation of CT numbers measured in a small area in an image of an IQ test phantom (Catphan), and the high spatial resolution (HSR) was evaluated by the number of line-pairs (LPN) visually recognizable in the image...
May 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28297279/difference-in-performance-between-3d-and-4d-cbct-for-lung-imaging-a-dose-and-image-quality-analysis
#8
Sheeba Thengumpallil, Kathleen Smith, Pascal Monnin, Jean Bourhis, François Bochud, Raphaël Moeckli
The study was to describe and to compare the performance of 3D and 4D CBCT imaging modalities by measuring and analyzing the delivered dose and the image quality. The 3D (Chest) and 4D (Symmetry) CBCT Elekta XVI lung IGRT protocols were analyzed. Dose profiles were measured with TLDs inside a dedicated phantom. The dosimetric indicator cone-beam dose index (CBDI) was evaluated. The image quality analysis was performed by assessing the contrast transfer function (CTF), the noise power spectrum (NPS) and the noise-equivalent quanta (NEQ)...
November 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28296311/analysis-of-setup-error-based-on-ctvision-for-nasopharyngeal-carcinoma-during-igrt
#9
Shuxu Zhang, Xiang Zhou, Quanbin Zhang, Shaohui Jiang, Ruihao Wang, Guoqian Zhang, Huaiyu Lei, Shengqu Lin
The aim of the present study was to investigate the role of CTVision in interfractional setup errors during intensity-modulated radiation therapy (IMRT) in 12 nasopharyngeal carcinoma (NPC) patients. The trend of setup errors as a function of time during a fractionated radiotherapy course was investigated, and the influence of reconstructive thickness on image reconstruction for setup errors was analyzed. The appropriate planning target volume (PTV) margin and planning risk volume (PRV) margin were defined to provide a reference for the design of IMRT for NPC...
July 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28290067/expert-system-classifier-for-adaptive-radiation-therapy-in-prostate-cancer
#10
Gabriele Guidi, Nicola Maffei, Claudio Vecchi, Giovanni Gottardi, Alberto Ciarmatori, Grazia Maria Mistretta, Ercole Mazzeo, Patrizia Giacobazzi, Frank Lohr, Tiziana Costi
A classifier-based expert system was developed to compare delivered and planned radiation therapy in prostate cancer patients. Its aim is to automatically identify patients that can benefit from an adaptive treatment strategy. The study predominantly addresses dosimetric uncertainties and critical issues caused by motion of hollow organs. 1200 MVCT images of 38 prostate adenocarcinoma cases were analyzed. An automatic daily re-contouring of structures (i.e. rectum, bladder and femoral heads), rigid/deformable registration and dose warping was carried out to simulate dose and volume variations during therapy...
March 13, 2017: Australasian Physical & Engineering Sciences in Medicine
https://www.readbyqxmd.com/read/28256898/the-future-of-image-guided-radiotherapy-will-be-mr-guided
#11
Julianne M Pollard, Zhifei Wen, Ramaswamy Sadagopan, Jihong Wang, Geoffrey S Ibbott
Advances in image-guided radiotherapy (IGRT) have allowed for dose escalation and more precise radiation treatment delivery. Each decade brings new imaging technologies to help improve radiotherapy patient setup. Currently, the most frequently used method of 3D pre-treatment image verification is performed with cone-beam CT. However, more recent developments have provided radiotherapy with the ability to have on-board magnetic resonance (MR) imaging coupled to the Tele-radiotherapy unit. This latest tool for treating cancer is known as MR-guided radiotherapy (MR-gRT) ...
March 3, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28255386/variation-in-uterus-position-prior-to-brachytherapy-of-the-cervix-a-case-report
#12
M T Georgescu, R Anghel
Rationale: brachytherapy is administered in the treatment of patients with locally advanced cervical cancer following chemoradiotherapy. Lack of local anatomy evaluation prior to this procedure might lead to the selection of an inappropriate brachytherapy applicator, increasing the risk of side effects (e.g. uterus perforation, painful procedure ...). Objective: To assess the movement of the uterus and cervix prior to brachytherapy in patients with gynecological cancer, in order to select the proper type of brachytherapy applicator...
January 2017: Journal of Medicine and Life
https://www.readbyqxmd.com/read/28244420/is-dose-deformation-invariance-hypothesis-verified-in-prostate-igrt
#13
Antoine Simon, Amandine Le Maitre, Mohamed Nassef, Bastien Rigaud, Joël Castelli, Oscar Acosta, Pascal Haigron, Caroline Lafond, Renaud de Crevoisier
PURPOSE: To assess dose uncertainties resulting from the dose deformation-invariance hypothesis in prostate cone beam computed tomography (CT)-based image guided radiation therapy (IGRT), namely to evaluate whether rigidly propagated planned dose distribution enables good estimation of fraction dose distributions. METHODS AND MATERIALS: Twenty patients underwent a CT scan for planning intensity modulated radiation therapy-IGRT delivering 80 Gy to the prostate, followed by weekly CT scans...
March 15, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28240007/delineation-of-margins-for-the-planning-target-volume-ptv-for-image-guided-radiotherapy-igrt-of-gastric-cancer-based-on-intrafraction-motion
#14
Paulina Leszczyńska, Wojciech Leszczyński, Jerzy Wydmański, Dębiec Kinga, Agnieszka Namysł Kaletka, Andrzej Tukiendorf, Leszek Hawrylewicz
Background: Application of the image-guided radiotherapy (IGRT) system for gastric cancer involving daily verification of patient positioning on the treatment machine allows minimisation of geometrical errors as a consequence of intra- and inter-fraction motion. The purpose of this study was to define the intrafraction motion in gastric cancer patients during a treatment session based on the IGRT system and designation of margins around the clinical target volume CTV (internal target volume ITV) necessary to delineate the planning target volume (PTV)...
January 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28237181/moderate-hypofractionated-postprostatectomy-volumetric-modulated-arc-therapy-with-daily-image-guidance-vmat-igrt-a%C3%A2-mono-institutional-report-on-feasibility-and-acute-toxicity
#15
Sergio Fersino, Umberto Tebano, Rosario Mazzola, Niccolò Giaj-Levra, Francesco Ricchetti, Gioacchino Di Paola, Alba Fiorentino, Gianluisa Sicignano, Stefania Naccarato, Ruggero Ruggieri, Stefano Cavalleri, Filippo Alongi
INTRODUCTION: The aim of this study was to evaluate the acute toxicity profiles of a moderate hypofractionated regimen with volumetric modulated arc therapy (VMAT) in patients with prostate cancer (PC) who underwent radical prostatectomy. MATERIAL AND METHODS: From December 2012 to February 2016, 125 patients, previously having undergone radical prostatectomy, received adjuvant (64 patients) or salvage (61 patients) radiotherapy (RT) inside an institutional protocol of moderate hypofractionation schedule using the VMAT technique (Varian RapidArc, Palo Alto, CA)...
February 6, 2017: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/28205452/in-vivo-dosimetry-in-uk-external-beam-radiotherapy-current-and-future-usage
#16
Niall D MacDougall, Michael Graveling, Vibeke N Hansen, Kevin Brownsword, Andrew Morgan
OBJECTIVE: Towards Safer Radiotherapy recommended that radiotherapy (RT) centres should have protocols in place for in vivo dosimetry (IVD) monitoring at the beginning of patient treatment courses (Donaldson S. Towards safer radiotherapy. R Coll Radiol 2008). This report determines IVD implementation in the UK in 2014, the methods used and makes recommendations on future use. METHODS: Evidence from peer-reviewed journals was used in conjunction with the first survey of UK RT centre IVD practice since the publication of Towards Safer Radiotherapy...
April 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28154882/transperineal-gold-marker-implantation-for-image-guided-external-beam-radiotherapy-of-prostate-cancer-a-single-institution-prospective-study
#17
Kliton Jorgo, Péter Ágoston, Tibor Major, Zoltán Takácsi-Nagy, Csaba Polgár
PURPOSE: To present the feasibility and complications of transperineal fiducial marker implantation in prostate cancer patients undergoing image-guided radiotherapy (IGRT) METHODS AND MATERIALS: Between November 2011 and April 2016, three radiopaque, gold-plated markers were transperineally implanted into the prostate of 300 patients under transrectal ultrasound guidance and with local anaesthesia. A week after the procedure patients filled in a questionnaire regarding pain, dysuria, urinary frequency, nocturia, rectal bleeding, hematuria, hematospermia or fever symptoms caused by the implantation...
February 2, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28113225/system-integration-and-in-vivo-testing-of-a-robot-for-ultrasound-guidance-and-monitoring-during-radiotherapy
#18
Hasan Sen, Muyinatu Lediju Bell, Yin Zhang, Kai Ding, Emad Boctor, John Wong, Iulian Iordachita, Peter Kazanzides
We are developing a cooperatively-controlled robot system for image-guided radiation therapy (IGRT) in which a clinician and robot share control of a 3D ultrasound (US) probe. IGRT involves two main steps: (1) planning/ simulation and (2) treatment delivery. The goals of the system are to provide guidance for patient setup and realtime target monitoring during fractionated radiotherapy of soft tissue targets, especially in the upper abdomen. To compensate for soft tissue deformations created by the probe, we present a novel workflow where the robot holds the US probe on the patient during acquisition of the planning computerized tomography (CT) image, thereby ensuring that planning is performed on the deformed tissue...
October 3, 2016: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28102960/nine-degrees-of-freedom-flexmap-for-a-cone-beam-computed-tomography-imaging-device-with-independently-movable-source-and-detector
#19
Peter Keuschnigg, Daniel Kellner, Karl Fritscher, Andrea Zechner, Ulrich Mayer, Philipp Huber, Felix Sedlmayer, Heinz Deutschmann, Philipp Steininger
PURPOSE: Couch-mounted cone-beam computed tomography (CBCT) imaging devices with independently rotatable x-ray source and flat-panel detector arms for acquisitions of arbitrary regions of interest (ROI) have recently been introduced in image-guided radiotherapy (IGRT). This work analyzes mechanical limitations and gravity-induced effects influencing the geometric accuracy of images acquired with arbitrary angular constellations of source and detector in nonisocentric trajectories, which is considered essential for IGRT...
January 2017: Medical Physics
https://www.readbyqxmd.com/read/28090640/in-the-era-of-igrt-and-small-and-focal-field-external-beam-radiotherapy-brachytherapy-is-a-dying-modality
#20
E Ishmael Parsai, Zoubir Ouhib, Colin G Orton
No abstract text is available yet for this article.
February 2017: Medical Physics
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