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https://www.readbyqxmd.com/read/28330963/decrease-in-a%C3%AE-42-predicts-dopa-resistant-gait-progression-in-early-parkinson-disease
#1
Lynn Rochester, Brook Galna, Sue Lord, Alison J Yarnall, Rosie Morris, Gordon Duncan, Tien K Khoo, Brit Mollenhauer, David J Burn
OBJECTIVE: This prospective observational study investigates the role of CSF biomarkers in predicting progression of dopa-resistant gait impairments in Parkinson disease (PD) in the first 36 months from diagnosis. METHODS: Quantitative gait analysis was carried out longitudinally using an instrumented walkway (GAITRite) in 108 people with PD and 130 age-matched controls. A subgroup of 44 people with PD underwent lumbar puncture from which a battery of CSF biomarkers was measured: β-amyloid 1-42 and 1-40 (Aβ42 and Aβ40), total and phosphorylated tau protein (t-tau/p-tau181), and α-synuclein (αSyn)...
March 22, 2017: Neurology
https://www.readbyqxmd.com/read/28327841/-assessment-of-local-and-systemic-inflammatory-parameters-of-peripheral-burn-in-an-animal-model
#2
Wilmary Torres, Liseth Mendoza, Hember Vicci, Antonio Eblen-Zajjur, María Navarro
To evaluate the edema volume and leukocyte, platelet, and fibrinogen count of peripheral burn in an animal model. The back left leg of Rattus norvegicus (experimental group) was placed in water at 60 °C for 60 seconds or at room temperature (control group). An analysis was carried out before and after the induced burn (at 4, 8, 12, and 24 h). The edema volume was determined by an orthogonal photo, the leukocyte and platelet counts were determined using automated equipment, and the fibrinogen count was determined using the gravimetric method...
October 2016: Revista Peruana de Medicina Experimental y Salud Pública
https://www.readbyqxmd.com/read/28321262/allium-stipitatum-extract-exhibits-in-vivo-antibacterial-activity-against-methicillin-resistant-staphylococcus-aureus-and-accelerates-burn-wound-healing-in-a-full-thickness-murine-burn-model
#3
Arunkumar Karunanidhi, Ehsanollah Ghaznavi-Rad, Jayakayatri Jeevajothi Nathan, Yusuf Abba, Alex van Belkum, Vasanthakumari Neela
The in vivo antibacterial and burn wound healing potency of Persian shallot bulbs (Allium stipitatum) were explored in a mice burn model infected with methicillin-resistant Staphylococcus aureus (MRSA). Hexane (ASHE) and dichloromethane (ASDE) extracts were tested. Female BALB/c mice were inflicted with third-degree thermal injury followed by infection with MRSA. ASHE and ASDE formulated with simple ointment base (SOB) at concentrations of 1%, 2%, and 5% (w/w) were topically applied to burn wounds twice a day for 20 days...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28320964/in-vivo-optophysiology-reveals-that-g-protein-activation-triggers-osmotic-swelling-and-increased-light-scattering-of-rod-photoreceptors
#4
Pengfei Zhang, Robert J Zawadzki, Mayank Goswami, Phuong T Nguyen, Vladimir Yarov-Yarovoy, Marie E Burns, Edward N Pugh
The light responses of rod and cone photoreceptors have been studied electrophysiologically for decades, largely with ex vivo approaches that disrupt the photoreceptors' subretinal microenvironment. Here we report the use of optical coherence tomography (OCT) to measure light-driven signals of rod photoreceptors in vivo. Visible light stimulation over a 200-fold intensity range caused correlated rod outer segment (OS) elongation and increased light scattering in wild-type mice, but not in mice lacking the rod G-protein alpha subunit, transducin (Gαt), revealing these responses to be triggered by phototransduction...
March 20, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28319773/potential-of-water-washing-of-rape-straw-on-thermal-properties-and-interactions-during-co-combustion-with-bituminous-coal
#5
Qiulin Ma, Lujia Han, Guangqun Huang
The aim of this work was to study the thermal properties and interactions during co-combustion of rape straw (RS) before and after water-washing with bituminous coal. A series of experiments was conducted to investigate the properties and interactions during co-combustion of RS with bituminous coal (at 10, 20, 40 and 60% RS). The feasibility and potential of water-washing as an RS pre-treatment was also explored. Reactivity and the amount of heat released followed a quadratic trend, while changes to the degree of interactions between the fuels conformed to a cosine curve...
March 7, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28318750/changes-in-patterns-of-treatment-of-burned-children-at-the-linkoping-burn-centre-sweden-2009-2014
#6
Moustafa Elmasry, Ingrid Steinvall, Islam Abdelrahman, Pia Olofsson, Folke Sjoberg
INTRODUCTION: Children are a relatively large group among patients with burns in Sweden. We changed the management of children's burns to a flexible, outpatient-based plan. The aim was to follow up the outpatient management for children's burns during the period 2009-2014, and track it, to find out to what extent the patients had been treated flexibly as outpatients, and to clarify the reasons behind those who did not fit in the plan. METHODS: Descriptive retrospective analysis dividing the patients into three groups: inpatients only, flexible management, and outpatients...
March 15, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28314935/a-disease-with-a-sweet-tooth-exploring-the-warburg-effect-in-alzheimer-s-disease
#7
REVIEW
Anna Atlante, Lidia de Bari, Antonella Bobba, Giuseppina Amadoro
After more than 80 years from the revolutionary discoveries of Otto Warburg, who observed high glucose dependency, with increased glycolysis and lactate production regardless of oxygen availability in most cancer cells, the 'Warburg effect' returns to the fore in neuronal cells affected by Alzheimer's disease (AD). Indeed, it seems that, in the mild phase of AD, neuronal cells "prefer" to use the energetically inefficient method of burning glucose by glycolysis, as in cancer, proving to become resistant to β-amyloid (Aβ)-dependent apoptosis...
March 17, 2017: Biogerontology
https://www.readbyqxmd.com/read/28314677/vulvovaginal-candidiasis-etiology-symptomatology-and-risk-factors
#8
L Mtibaa, N Fakhfakh, A Kallel, S Belhadj, N Belhaj Salah, N Bada, K Kallel
OBJECTIVE: To determine epidemiological, clinical and mycological characteristics of vulvovaginal candidiasis (VVC) in Tunisian population and to evaluate predisposing factors. PATIENTS AND METHODS: In this retrospective study, 2160 vaginal swabs were performed over 2 years (January 2014-December 2015). It was carried out at the laboratory of Parasitology and Mycology, Rabta Hospital in Tunisia. After swab collecting, direct examination and culture on Sabouraud Chloramphenicol and Sabouraud Chloramphenicol Actidione media were implemented to research yeasts...
March 14, 2017: Journal de Mycologie Médicale
https://www.readbyqxmd.com/read/28293640/cost-analysis-of-a-novel-enzymatic-debriding-agent-for-management-of-burn-wounds
#9
Giuseppe Giudice, Angela Filoni, Giulio Maggio, Domenico Bonamonte, Michelangelo Vestita
Introduction. Given its efficacy and safety, NexoBrid™ (NXB) has become part of our therapeutic options in burns treatment with satisfactory results. However, no cost analysis comparing NXB to the standard of care (SOC) has been carried out as of today. Aim. To assess the cost of treatment with NXB and compare it to the SOC cost. Methods. 20 patients with 14-22% of TBSA with an intermediate-deep thermal burn related injury were retrospectively and consecutively included. 10 of these patients were treated with the SOC, while the other 10 with NXB...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28290624/thick-melanoma-in-tuscany
#10
Alessandra Chiarugi, Paolo Nardini, Lorenzo Borgognoni, Paola Brandani, Gianni Gerlini, Pietro Rubegni, Arianna Lamberti, Camilla Salvini, Giovanni Lo Scocco, Roberto Cecchi, Riccardo Sirna, Stefano Lorenzi, Riccardo Gattai, Silvio Battistini, Emanuele Crocetti
BACKGROUND: The epidemiologic trends of cutaneous melanoma are similar in several countries with a Western-type life style, where there is a progressive increasing incidence and a low but not decreasing mor- tality, or somewhere an increase too, especially in the older age groups. Also in Tuscany there is a steady rise in incidence with prevalence of in situ and invasive thin melanomas, with also an increase of thick melanomas. It is necessary to reduce the frequency of thick melanomas to reduce specific mortality...
March 14, 2017: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/28289359/fast-and-specific-detection-of-pseudomonas-aeruginosa-from-other-pseudomonas-species-by-pcr
#11
G Jami Al-Ahmadi, R Zahmatkesh Roodsari
Pseudomonas aeruginosa is an important life-threatening nosocomial pathogen that plays a prominent role in wound infections of burned patients. We designed this study to identify the isolates of P. aeruginosa recovered from burned patients at the genus and species level through primers targeting oprI and oprL genes, and analyzed their antimicrobial resistance pattern. Over a 2-month period, wound samples were taken from burned patients and plated on MacConkey agar. All suspected colonies were primarily screened for P...
December 31, 2016: Annals of Burns and Fire Disasters
https://www.readbyqxmd.com/read/28286783/decreasing-incidence-of-cutaneous-chemical-burns-in-a-resource-limited-burn-centre-is-this-a-positive-effect-of-modernization
#12
R E E Nnabuko, C P Okoye, I S Ogbonnaya, Egi Isiwele
BACKGROUND: Burns present a devastating injury to patients. Burns caused by chemical agents, present a worse scenario. In a resource limited country like Nigeria, readily available sources of these corrosive agents are mainly from lead-acid battery vendors and to some extent local small scale soap manufacturers who use caustic soda. We hypothesized that with the reduction in small scale soap manufacturing and increasing trend towards modernization in the use of dry cell batteries, chemical burns may be on the decline, and we sought to investigate this...
2017: Burns and trauma
https://www.readbyqxmd.com/read/28282004/five-year-retrospective-review-of-blunt-renal-injuries-at-a-level-i-trauma-center
#13
Jessica Burns, Megan Brown, Zakaria I Assi, Eric J Ferguson
We report the experience of a Level I trauma center in the management of blunt renal injury during a 5-year period, with special attention to those treated using angiography with embolization. The institutional trauma registry was queried for all patients with blunt renal injury between September 1, 2009 and August 30, 2014. Each injury was graded using the American Association for the Surgery of Trauma guidelines. Patients that underwent angiography with embolization were reviewed for case-specific information including imaging findings, treatment, materials used, clinical course, and mortality...
February 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28280403/-medical-students-burn-out-need-of-student-mentor-and-support-groups-and-emotional-resilience-skills-training-to-be-a-part-of-medical-school-curriculum
#14
COMMENT
Maria Shoaib, Anoshia Afzal, Muhammad Aadil
No abstract text is available yet for this article.
2017: Advances in Medical Education and Practice
https://www.readbyqxmd.com/read/28271966/a-national-survey-of-attitudes-toward-intimate-partner-violence-among-married-women-in-kazakhstan-kyrgyzstan-and-tajikistan-implications-for-health-prevention-and-intervention
#15
Manisha Joshi, Saltanat Childress
Attitudes toward intimate partner violence (IPV) can affect the prevalence of IPV, response of victims' to IPV (e.g., whether to seek help), and the response of professionals (e.g., police, social workers, health care professionals) to IPV. Knowledge about IPV-related attitudes is essential for developing effective social work and violence-related programs. Using data from the 2005-2006 Multiple Indicator Cluster Surveys, this study examines attitudes toward IPV and socio-demographic predictors of these attitudes among married women in Kazakhstan, Kyrgyzstan, and Tajikistan...
April 2017: Social Work in Health Care
https://www.readbyqxmd.com/read/28271777/-burning-platform-warning-for-nhs
#16
(no author information available yet)
The NHS 'stands on a burning platform', with four out of five trusts needing to improve on patient safety, the Care Quality Commission's (CQC) chief inspector of hospitals said.
March 8, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28270706/patients-with-burning-mouth-sensations-a-clinical-investigation-of-causative-factors-in-a-group-of-compete-denture-wearers-jordanian-population
#17
Gadeer Elea Mukatash-Nimri, Marwan A Al-Nimri, Omar G Al-Jadeed, Zaid R Al-Zobe, Khuzama K Aburumman, Nader A Masarwa
AIM: To find out the prevalence of "true" burning mouth syndrome and study the association between patients' spontaneous complaints of burning mouth and systemic conditions in a group of middle age and elderly "denture wearers" patients in Jordan. METHODS: A group of 129 patients (112 female and 17 male) of "complete denture wearers" subjects aged 40 years and over attended prosthetic clinic at King Hussein Medical Hospital complaining from oral burning, with no oral lesion possibly responsible for the burning sensations were selected...
January 2017: Saudi Dental Journal
https://www.readbyqxmd.com/read/28270316/donovanosis-with-bowen-disease
#18
Tarun Narang, Ashwini Manhas, Bhushan Kumar
A 45-year-old farmer presented with ulcers and plaques over his scrotum for the past 4 to 5 years. The condition started as a small lesion on the shaft of the penis, which improved with treatment; however, after 2 to 3 months, papulonodular lesions developed on the scrotum, which increased in size and subsequently broke down to form ulcers. He denied drug abuse but had a history of multiple unprotected sexual exposures. He was prescribed oral antibiotics, which improved the lesions, but he failed to take the antibiotics for more than a week...
2017: Skinmed
https://www.readbyqxmd.com/read/28268175/dissemination-of-carbapenem-resistant-acinetobacter-baumannii-in-patients-with-burn-injuries
#19
Saeed Shoja, Mojtaba Moosavian, Soodabeh Rostami, Abbas Farahani, Amir Peymani, Khadijeh Ahmadi, Nasim Ebrahimifard
BACKGROUND: Carbapenem-resistant Acinetobacter baumannii has emerged as an important cause of infection in burn patients. This study aimed to characterize the antimicrobial susceptibility pattern, determine the prevalence of oxacillinase and metallo-beta-lactamase (MBL) genes, and type the A. baumannii isolates obtained from burn patients. METHODS: During a 1-year period, a total of 40 nonduplicated isolates of A. baumannii were obtained from burn patients who were hospitalized in the Taleghani Burn Hospital in Ahvaz, in the southwest of Iran...
March 3, 2017: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/28262656/-hermeneutic-phenomenological-study-on-caring-experience-of-the-mothers-of-children-with-epilepsy
#20
Woo Joung Joung, Myungsun Yi
PURPOSE: The purpose of this study was to develop a deeper understanding of the experience of mothers caring for children with epilepsy. METHODS: Data were collected through individual in-depth interviews and observation from 12 mothers of children with epilepsy. Data were collected from December, 2014 to February, 2015 and analyzed using van Manen's hermeneutic phenomenological methodology to identify essential themes of their experience. RESULTS: The essential themes that fit into the context of the 4-existential grounds of time, body, other people, and space were: Lived time-ongoing influence of the past, living in insecure present, fearful future with no answer; Lived body-bonded body, burned out state; Lived other-burden but also support, shrunken down; Lived space-narrowed range of activity, widened horizon...
February 2017: Journal of Korean Academy of Nursing
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