keyword
MENU ▼
Read by QxMD icon Read
search

Shibis

keyword
https://www.readbyqxmd.com/read/29666653/mesenchymal-stem-cells-in-oriented-plga-acecm-composite-scaffolds-enhance-structure-specific-regeneration-of-hyaline-cartilage-in-a-rabbit-model
#1
Weimin Guo, Xifu Zheng, Weiguo Zhang, Mingxue Chen, Zhenyong Wang, Chunxiang Hao, Jingxiang Huang, Zhiguo Yuan, Yu Zhang, Mingjie Wang, Jiang Peng, Aiyuan Wang, Yu Wang, Xiang Sui, Wenjing Xu, Shuyun Liu, Shibi Lu, Quanyi Guo
Articular cartilage lacks a blood supply and nerves. Hence, articular cartilage regeneration remains a major challenge in orthopedics. Decellularized extracellular matrix- (ECM-) based strategies have recently received particular attention. The structure of native cartilage exhibits complex zonal heterogeneity. Specifically, the development of a tissue-engineered scaffold mimicking the aligned structure of native cartilage would be of great utility in terms of cartilage regeneration. Previously, we fabricated oriented PLGA/ACECM (natural, nanofibrous, articular cartilage ECM) composite scaffolds...
2018: Stem Cells International
https://www.readbyqxmd.com/read/29611112/sedation-practices-in-gastrointestinal-endoscopy-a-survey-from-southern-india
#2
Prakash Zacharias, Shibi Mathew, John Mathews, Aby Somu, Maya Peethambaran, Menon Prashanth, Mathew Philip
Gastrointestinal endoscopies can cause an unpleasant experience for the patient. In India, most endoscopists follow a common institutional policy for sedation. The aim of this study was to analyze the sedation practices in various endoscopy centers across southern India. Data were collected with the help of a structured questionnaire given to a senior endoscopist of the center. Data from the completed questionnaire were later analyzed. Data were obtained from 19 centers across southern India. All endoscopy suites had central oxygen supply and emergency cart...
April 3, 2018: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/29483834/analysis-of-early-stage-osteonecrosis-of-the-human-femoral-head-and-the-mechanism-of-femoral-head-collapse
#3
Cheng Wang, Haoye Meng, Yu Wang, Bin Zhao, Chenyang Zhao, Weijia Sun, Yun Zhu, Bingxing Han, Xueling Yuan, Ruoxi Liu, Xin Wang, Aiyuan Wang, Quanyi Guo, Jiang Peng, Shibi Lu
We explored the mechanism of early stage osteonecrotic femoral head collapse by analyzing and comparing different regions in human osteonecrotic femoral head samples. Eight osteonecrotic femoral heads (ARCO II-III) were obtained from patients undergoing total hip arthroplasty. Bone structure was observed and evaluated by micro-computed tomography (CT) scans and pathology. Osteoblast and osteoclast activities were detected by tartrate-resistant acid phosphatase, alkaline phosphatase, and immunofluorescent staining...
2018: International Journal of Biological Sciences
https://www.readbyqxmd.com/read/29396874/gross-anatomy-examination-performances-in-relation-to-medical-students-knowledge-of-classical-latin-and-greek
#4
Shiby Stephens, Bernard John Moxham
The ability of medical students to acquire anatomical and medical terminologies could be influenced by their knowledge of classical Greek and Latin. In a previous study (Stephens and Moxham, 2016), it was reported that, while newly recruited medical students have a very favourable attitude towards the need to understand these classical languages, final year students see no benefit. In this study, we tested the hypothesis that, regardless of attitude, students in the initial stages of their medical education perform better at both summative and formative anatomy examinations if they have prior knowledge of Greek and Latin...
February 3, 2018: Clinical Anatomy
https://www.readbyqxmd.com/read/29391278/human-umbilical-cord-wharton-s-jelly-mesenchymal-stem-cells-combined-with-an-acellular-cartilage-extracellular-matrix-scaffold-improve-cartilage-repair-compared-with-microfracture-in-a-caprine-model
#5
Yu Zhang, Shuyun Liu, Weimin Guo, Mingjie Wang, Chunxiang Hao, Shuang Gao, Xueliang Zhang, Xu Li, Mingxue Chen, Xiaoguang Jing, Zehao Wang, Jiang Peng, Shibi Lu, Quanyi Guo
OBJECTIVE: As a novel and promising seed cell, human umbilical cord Wharton's jelly mesenchymal stem cells(hWJMSCs) are widely applied in tissue engineering. However, whether hWJMSCs can better repair and regenerate the articular cartilage in big animals than microfracture(MF, a predominant clinical treatment strategy for damaged cartilage) is unclear. Evaluation of the validity, and safety of hWJMSCs in a caprine model with a full-thickness femoral condyle articular cartilage defect, compared with MF is required...
January 29, 2018: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/29375677/quantifying-the-degradation-of-degradable-implants-and-bone-formation-in-the-femoral-condyle-using-micro-ct-3d-reconstruction
#6
Yichi Xu, Haoye Meng, Heyong Yin, Zhen Sun, Jiang Peng, Xiaolong Xu, Quanyi Guo, Wenjing Xu, Xiaoming Yu, Zhiguo Yuan, Bo Xiao, Cheng Wang, Yu Wang, Shuyun Liu, Shibi Lu, Zhaoxu Wang, Aiyuan Wang
Degradation limits the application of magnesium alloys, and evaluation methods for non-traumatic in vivo quantification of implant degradation and bone formation are imperfect. In the present study, a micro-arc-oxidized AZ31 magnesium alloy was used to evaluate the degradation of implants and new bone formation in 60 male New Zealand white rabbits. Degradation was monitored by weighing the implants prior to and following implantation, and by performing micro-computed tomography (CT) scans and histological analysis after 1, 4, 12, 24, 36, and 48 weeks of implantation...
January 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29214173/fabrication-and-in-vitro-study-of-tissue-engineered-cartilage-scaffold-derived-from-wharton-s-jelly-extracellular-matrix
#7
Tongguang Xiao, Weimin Guo, Mingxue Chen, Chunxiang Hao, Shuang Gao, Jingxiang Huang, Zhiguo Yuan, Yu Zhang, Mingjie Wang, Penghao Li, Jiang Peng, Aiyuan Wang, Yu Wang, Xiang Sui, Li Zhang, Wenjing Xu, Shibi Lu, Heyong Yin, Jianhua Yang, Shuyun Liu, Quanyi Guo
The scaffold is a key element in cartilage tissue engineering. The components of Wharton's jelly are similar to those of articular cartilage and it also contains some chondrogenic growth factors, such as insulin-like growth factor I and transforming growth factor- β . We fabricated a tissue-engineered cartilage scaffold derived from Wharton's jelly extracellular matrix (WJECM) and compared it with a scaffold derived from articular cartilage ECM (ACECM) using freeze-drying. The results demonstrated that both WJECM and ACECM scaffolds possessed favorable pore sizes and porosities; moreover, they showed good water uptake ratios and compressive moduli...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29132634/a-model-to-determine-payments-associated-with-radiology-procedures
#8
Thusitha Mabotuwana, Christopher S Hall, Shiby Thomas, Christoph Wald
OBJECTIVE: Across the United States, there is a growing number of patients in Accountable Care Organizations and under risk contracts with commercial insurance. This is due to proliferation of new value-based payment models and care delivery reform efforts. In this context, the business model of radiology within a hospital or health system context is shifting from a primary profit-center to a cost-center with a goal of cost savings. Radiology departments need to increasingly understand how the transactional nature of the business relates to financial rewards...
December 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/29110690/autologous-cell-derived-tissue-engineered-cartilage-for-repairing-articular-cartilage-lesions-in-the-knee-study-protocol-for-a-randomized-controlled-trial
#9
Ning Ma, Hongxia Wang, Xian Xu, Yiqun Wan, Yufeng Liu, Mingjie Wang, Wen Yu, Yongjing Dai, Jiang Peng, Quanyi Guo, Changlong Yu, Shibi Lu
BACKGROUND: Spontaneous recovery from articular cartilage injury is difficult, and the ongoing progression of disease can eventually lead to osteoarthritis. Currently, there is no effective non-surgical treatment for articular cartilage injury. Arthroscopic debridement and microfracture surgery are performed for fibrocartilage repair. But fibrocartilage is different from normal articular cartilage, and functional recovery is not satisfactory. Therefore, it is necessary to develop more effective techniques for articular cartilage repair...
November 6, 2017: Trials
https://www.readbyqxmd.com/read/29091557/single-dose-gene-replacement-therapy-for-spinal-muscular-atrophy
#10
Jerry R Mendell, Samiah Al-Zaidy, Richard Shell, W Dave Arnold, Louise R Rodino-Klapac, Thomas W Prior, Linda Lowes, Lindsay Alfano, Katherine Berry, Kathleen Church, John T Kissel, Sukumar Nagendran, James L'Italien, Douglas M Sproule, Courtney Wells, Jessica A Cardenas, Marjet D Heitzer, Allan Kaspar, Sarah Corcoran, Lyndsey Braun, Shibi Likhite, Carlos Miranda, Kathrin Meyer, K D Foust, Arthur H M Burghes, Brian K Kaspar
BACKGROUND: Spinal muscular atrophy type 1 (SMA1) is a progressive, monogenic motor neuron disease with an onset during infancy that results in failure to achieve motor milestones and in death or the need for mechanical ventilation by 2 years of age. We studied functional replacement of the mutated gene encoding survival motor neuron 1 (SMN1) in this disease. METHODS: Fifteen patients with SMA1 received a single dose of intravenous adeno-associated virus serotype 9 carrying SMN complementary DNA encoding the missing SMN protein...
November 2, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/29020967/an-updated-meta-analysis-of-the-asporin-gene-d-repeat-in-knee-osteoarthritis-effects-of-gender-and-ethnicity
#11
Ruoxi Liu, Xueling Yuan, Jing Yu, Qi Quan, Haoye Meng, Cheng Wang, Aiyuan Wang, Quanyi Guo, Jiang Peng, Shibi Lu
BACKGROUND: Knee osteoarthritis (KOA) is the most prevalent form of knee joint disease and characterized by the progressive degeneration of articular cartilage. Although pathology of KOA remains unknown, genetic factors are considered to be the major cause. Asporin is a group of biologically active components of extracellular matrix (ECM) in articular cartilage, and asporin gene (ASPN) D-repeat polymorphism was reported to be associated with KOA. Thus, our meta-analysis is aimed at investigation of the association between asporin D-repeat polymorphism and susceptibility of KOA...
October 11, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28892553/impulsivity-and-sensation-seeking-personality-traits-as-predictors-of-substance-use-among-university-students
#12
Ayman M Hamdan-Mansour, Khadejah F Mahmoud, Ahmad N Al Shibi, Diana H Arabiat
The purpose of the current study was to investigate the relationship between substance use and impulsivity and sensation-seeking personality traits among 655 university students using a cross-sectional, descriptive, correlational design. A significant correlation was found between students' impulsivity level scores and frequency of substance use (r = 0.11, p < 0.05). A positive correlation was found between frequency of substance use and sensation-seeking levels (r = 0.2, p < 0.05), as well as impulsivity levels (r = 0...
January 1, 2018: Journal of Psychosocial Nursing and Mental Health Services
https://www.readbyqxmd.com/read/28718671/freeze-dried-and-irradiated-allograft-bone-combined-with-fresh-autologous-coagula-promotes-angiogenesis-in-an-ectopic-bone-allograft-implantation-model
#13
Haibo Lu, Haoye Meng, Shibi Lu, Ling Qin, Bin Zhao, Aiyuan Wang, Jiang Peng, Wenjing Xu, Quanyi Guo, Jian Zhang
BACKGROUND: Freeze-dried and irradiated allograft bone (FIAB) is more easily impacted than fresh-frozen allograft bone (FAB), but has weaker incorporation efficiency. We combined FIAB with fresh autologous coagula to enhance donor-host incorporation after impaction during hip revision. METHODS: Thirty adult male Sprague-Dawley (SD) rats were sacrificed for bone allograft harvesting, and nine male rats were subjected to ectopic bone allograft implantation. For each rat, the container on the left (study) side was filled with freeze-dried allograft bone powder and fresh autologous blood coagula, whereas the right (control) side was filled with freeze-dried allograft bone powder and physiological saline...
July 18, 2017: Connective Tissue Research
https://www.readbyqxmd.com/read/28686244/3d-printed-porous-ceramic-scaffolds-for-bone-tissue-engineering-a-review
#14
REVIEW
Yu Wen, Sun Xun, Meng Haoye, Sun Baichuan, Chen Peng, Liu Xuejian, Zhang Kaihong, Yang Xuan, Peng Jiang, Lu Shibi
This study summarizes the recent research status and development of three-dimensional (3D)-printed porous ceramic scaffolds in bone tissue engineering. Recent literature on 3D-printed porous ceramic scaffolds was reviewed. Compared with traditional processing and manufacturing technologies, 3D-printed porous ceramic scaffolds have obvious advantages, such as enhancement of the controllability of the structure or improvement of the production efficiency. More sophisticated scaffolds were fabricated by 3D printing technology...
August 22, 2017: Biomaterials Science
https://www.readbyqxmd.com/read/28548713/co-culture-systems-based-strategies-for-articular-cartilage-tissue-engineering
#15
REVIEW
Yu Zhang, Weimin Guo, Mingjie Wang, Chunxiang Hao, Liang Lu, Shuang Gao, Xueliang Zhang, Xu Li, Mingxue Chen, Penghao Li, Peng Jiang, Shibi Lu, Shuyun Liu, Quanyi Guo
Cartilage engineering facilitates repair and regeneration of damaged cartilage using engineered tissue that restores the functional properties of the impaired joint. The seed cells used most frequently in tissue engineering, are chondrocytes and mesenchymal stem cells. Seed cells activity plays a key role in the regeneration of functional cartilage tissue. However, seed cells undergo undesirable changes after in vitro processing procedures, such as degeneration of cartilage cells and induced hypertrophy of mesenchymal stem cells, which hinder cartilage tissue engineering...
March 2018: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/28261617/repair-of-osteochondral-defects-using-human-umbilical-cord-wharton-s-jelly-derived-mesenchymal-stem-cells-in-a-rabbit-model
#16
Shuyun Liu, Yanhui Jia, Mei Yuan, Weimin Guo, Jingxiang Huang, Bin Zhao, Jiang Peng, Wenjing Xu, Shibi Lu, Quanyi Guo
Umbilical cord Wharton's jelly-derived mesenchymal stem cell (WJMSC) is a new-found mesenchymal stem cell in recent years with multiple lineage potential. Due to its abundant resources, no damage procurement, and lower immunogenicity than other adult MSCs, WJMSC promises to be a good xenogenous cell candidate for tissue engineering. This in vivo pilot study explored the use of human umbilical cord Wharton's jelly mesenchymal stem cells (hWJMSCs) containing a tissue engineering construct xenotransplant in rabbits to repair full-thickness cartilage defects in the femoral patellar groove...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28246531/advances-and-prospects-in-stem-cells-for-cartilage-regeneration
#17
REVIEW
Mingjie Wang, Zhiguo Yuan, Ning Ma, Chunxiang Hao, Weimin Guo, Gengyi Zou, Yu Zhang, Mingxue Chen, Shuang Gao, Jiang Peng, Aiyuan Wang, Yu Wang, Xiang Sui, Wenjing Xu, Shibi Lu, Shuyun Liu, Quanyi Guo
The histological features of cartilage call attention to the fact that cartilage has a little capacity to repair itself owing to the lack of a blood supply, nerves, or lymphangion. Stem cells have emerged as a promising option in the field of cartilage tissue engineering and regenerative medicine and could lead to cartilage repair. Much research has examined cartilage regeneration utilizing stem cells. However, both the potential and the limitations of this procedure remain controversial. This review presents a summary of emerging trends with regard to using stem cells in cartilage tissue engineering and regenerative medicine...
2017: Stem Cells International
https://www.readbyqxmd.com/read/28114317/the-scaphoid-safe-zone-a-radiographic-simulation-study-to-prevent-cortical-perforation-arising-from-different-views
#18
Qi Quan, Lei Hong, Biao Chang, Ruoxi Liu, Yun Zhu, Jiang Peng, Qing Zhao, Shibi Lu
PURPOSE: The purpose of this study was to simulate and calculate the probability of iatrogenic perforation of the scaphoid cortical bone when internal fixation appeared to be safe on radiographs. The results will assist surgeons in determining proper screw placement. METHODS: Thirty scaphoids were reconstructed using computed tomography data and image-processing software. Different central axes were determined by the software to simulate the surgical views. The safe zone (SZ) and risk zone (RZ) were identified on the axial projection radiographs by comparing the scaphoid bone stenosis measured by the fluoroscopic radiographs with a three-dimensional reconstruction of the scaphoid stenosis...
2017: PloS One
https://www.readbyqxmd.com/read/27982575/a-model-to-stabilize-co2-uptake-capacity-during-carbonation-calcination-cycles-and-its-case-of-cao-mgo
#19
Qiancheng Zhu, Shibi Zeng, Ying Yu
Nowadays, capturing anthropogenic CO2 in a highly efficient and cost-effective way is one of the most challenging issues. Herein, the key parameters to stabilize CO2 uptake capacity have been studied based on four kinds of pure calcium oxides (CaO) prepared by a simple calcination method with four different calcium precursors. A simple ideal particle model was proposed to illustrate the uniform distribution of pure CaO, in which the CO2 uptake capacity is positively related with surface area of CaO particles and the stability is opposite to the distance between two CaO particles after carbonation...
January 3, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/27897383/photoswitchable-and-water-soluble-fluorescent-nano-aggregates-based-on-a-diarylethene-dansyl-dyad-and-liposome
#20
Hongbo Cheng, Pin Ma, Yanan Wang, Guofei Hu, Shibi Fang, Yanyan Fang, Yuan Lin
In this work, a unique approach is developed to generate photoswitchable and water-soluble fluorescent nano-aggregates. Initially, a new light-controlled diarylethene-dansyl dyad DAE 1 is formed by linking two dansyl fluorophores covalently to a symmetrical dithienylethene backbone, whose photophysical properties can be reversibly switched by optical stimuli. Subsequently, the water insolubility of the molecular switch 1 is overcome by incorporating it into the bilayer of liposome DPPC (1,2-dihexadecanoyl-sn-glycero-3-phosphocholine) in water...
January 17, 2017: Chemistry, An Asian Journal
keyword
keyword
12343
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"