keyword
MENU ▼
Read by QxMD icon Read
search

Juvenile Idiopathic Arthritis

keyword
https://www.readbyqxmd.com/read/28431162/risk-of-serious-bacterial-infection-associated-with-tumour-necrosis-factor-alpha-inhibitors-in-children-with-juvenile-idiopathic-arthritis
#1
Wan-Ju Lee, Todd A Lee, Katie J Suda, Gregory S Calip, Leslie Briars, Glen T Schumock
Objectives.: TNF-α inhibitors (TNFIs) have a black box warning for increased risk of serious infection that was based on evidence from studies of adults. Evidence of the association is lacking for children. We aimed to examine the risk of infection posed by TNFIs compared with DMARDs in children with JIA. Methods.: We conducted a cohort study using the 2009-13 Truven MarketScan Commercial Claims and Encounters database. Children <16 years old with JIA who initiated monotherapy with TNFIs or DMARDs were identified and followed for occurrence of serious bacterial infection requiring hospitalization...
April 18, 2017: Rheumatology
https://www.readbyqxmd.com/read/28428675/uveitis-associated-with-juvenile-idiopathic-arthritis-our-observations
#2
Almira Cosickic, Meliha Halilbasic, Amela Selimovic, Harun Avdagic
INTRODUCTION: Uveitis as extra-articular manifestation of juvenile idiopathic arthritis (JIA) is present in 20% of children with the persistent form, in 30% with the extended oligoarticular form, while it is present in psoriatic and polyarticular rheumatoid factor (RF) negative arthritis in 10% and 14%, respectively. AIM: The aim of the study was to evaluate the frequency of uveitis and its complications in children with JIA. MATERIAL AND METHODS: A retrospective study was conducted with an analysis of the medical records of children with JIA who were treated for the last 5 years...
February 2017: Medical Archives
https://www.readbyqxmd.com/read/28427313/sensitivity-of-a-juvenile-subject-specific-musculoskeletal-model-of-the-ankle-joint-to-the-variability-of-operator-dependent-input
#3
Iain Hannah, Erica Montefiori, Luca Modenese, Joe Prinold, Marco Viceconti, Claudia Mazzà
Subject-specific musculoskeletal modelling is especially useful in the study of juvenile and pathological subjects. However, such methodologies typically require a human operator to identify key landmarks from medical imaging data and are thus affected by unavoidable variability in the parameters defined and subsequent model predictions. The aim of this study was to thus quantify the inter- and intra-operator repeatability of a subject-specific modelling methodology developed for the analysis of subjects with juvenile idiopathic arthritis...
May 2017: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/28426894/characteristics-and-course-of-enthesitis-in-a-juvenile-idiopathic-arthritis-inception-cohort
#4
Dax G Rumsey, Jaime Guzman, Alan M Rosenberg, Adam M Huber, Rosie Scuccimarri, Natalie J Shiff, Alessandra Bruns, Brian M Feldman, Dean T Eurich
Objective To describe the prevalence, associated characteristics, and course of enthesitis in a juvenile idiopathic arthritis (JIA) inception cohort. Methods Canadian children newly diagnosed with JIA between 2005 and 2010 were categorized using ILAR criteria at the 6-month visit and followed in the ReACCh-Out cohort for up to 5 years. The presence of entheseal tenderness on examination at 33 sites shown on a homunculus was recorded at 0, 6, 12, 18, 24, 36, 48 and 60 months after enrolment. Enthesitis was defined as entheseal tenderness at more than one site or on more than one occasion...
April 20, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28424093/a-survey-of-national-and-multi-national-registries-and-cohort-studies-in-juvenile-idiopathic-arthritis-challenges-and-opportunities
#5
Timothy Beukelman, Janneke Anink, Lillemor Berntson, Ciaran Duffy, Justine A Ellis, Mia Glerup, Jaime Guzman, Gerd Horneff, Lianne Kearsley-Fleet, Ariane Klein, Jens Klotsche, Bo Magnusson, Kirsten Minden, Jane E Munro, Martina Niewerth, Ellen Nordal, Nicolino Ruperto, Maria Jose Santos, Laura E Schanberg, Wendy Thomson, Lisette van Suijlekom-Smit, Nico Wulffraat, Kimme Hyrich
BACKGROUND: To characterize the existing national and multi-national registries and cohort studies in juvenile idiopathic arthritis (JIA) and identify differences as well as areas of potential future collaboration. METHODS: We surveyed investigators from North America, Europe, and Australia about existing JIA cohort studies and registries. We excluded cross-sectional studies. We captured information about study design, duration, location, inclusion criteria, data elements and collection methods...
April 19, 2017: Pediatric Rheumatology Online Journal
https://www.readbyqxmd.com/read/28420491/telemedicine-for-patients-with-rheumatic-diseases-systematic-review-and-proposal-for-research-agenda
#6
REVIEW
Matteo Piga, Ignazio Cangemi, Alessandro Mathieu, Alberto Cauli
OBJECTIVE: To systematically review the scientific literature regarding tele-rheumatology and draw conclusions about feasibility, effectiveness, and patient satisfaction. METHODS: PubMed, Scopus, and Cochrane database searches were performed (April 2016) using relevant MeSH and keyword terms for telemedicine and rheumatic diseases. Articles were selected if reporting outcomes for feasibility, effectiveness, and patient satisfaction and methodologically appraised using the Cochrane Collaboration's tool for assessing risk of bias and a modified version of CONSORT 2010 Statement...
March 22, 2017: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/28418334/juvenile-idiopathic-arthritis
#7
Kenan Barut, Amra Adrovic, Sezgin Şahin, Özgür Kasapçopur
Juvenile idiopathic arthritis is the most common chronic rheumatic disease of unknown aetiology in childhood and predominantly presents with peripheral arthritis. The disease is divided into several subgroups, according to demographic characteristics, clinical features, treatment modalities and disease prognosis. Systemic juvenile idiopathic arthritis, which is one of the most frequent disease subtypes, is characterized by recurrent fever and rash. Oligoarticular juvenile idiopathic arthritis, common among young female patients, is usually accompanied by anti-nuclear antibodie positivity and anterior uveitis...
April 5, 2017: Balkan Medical Journal
https://www.readbyqxmd.com/read/28416939/a-systemic-onset-juvenile-idiopathic-arthritis-patient-with-reduced-anakinra-treatment-admitted-with-an-attack
#8
Dilek Yilmaz, Mediha Akcan, Semiha Terlemez, Ferah Sonmez, Abdullah Baris Akcan
Interleukin-1 plays an important role in the pathogenesis of systemic-onset juvenile idiopathic arthritis (SoJIA), and the use of anti-interleukin-1 therapy has been increasing. We report a case of a 14-year-old male patient with SoJIA. He was in remission with anakinra treatment for almost 2 years. When we extended the therapeutic range and decreased the dose (1 mg/kg twice a week), he developed symptoms mimicking pulmonary embolism and cardiac ischemia. Increased cardiac enzyme levels and echocardiographic findings were interpreted as myopericarditis...
February 2017: Eurasian Journal of Medicine
https://www.readbyqxmd.com/read/28416023/the-new-childhood-arthritis-and-rheumatology-research-alliance-carra-registry-design-rationale-and-characteristics-of-patients-enrolled-in-the-first-12%C3%A2-months
#9
Timothy Beukelman, Yukiko Kimura, Norman T Ilowite, Kelly Mieszkalski, Marc D Natter, Grendel Burrell, Brian Best, Jason Jones, Laura E Schanberg
BACKGROUND: Herein we describe the history, design, and rationale of the new Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry and present the characteristics of patients with juvenile idiopathic arthritis (JIA) enrolled in the first 12 months of operation. METHODS: The CARRA Registry began prospectively collecting data in the United States and Canada in July 2015 to evaluate the safety of therapeutic agents in persons with childhood-onset rheumatic disease, initially restricted to JIA...
April 17, 2017: Pediatric Rheumatology Online Journal
https://www.readbyqxmd.com/read/28415953/influence-of-etanercept-on-leptin-and-ghrelin-secretion-in-children-with-juvenile-idiopathic-arthritis
#10
Izabela Maciejewska-Paszek, Elżbieta Grochowska-Niedworok, Andrzej Siwiec, Anna Gruenpeter, Lechosław Dul, Tomasz Irzyniec
Objective To assess possible changes in leptin and ghrelin secretion due to etanercept in juvenile idiopathic arthritis (JIA). Methods 50 patients with JIA and 16 age-matched controls were enrolled into this prospective, cross-sectional study. Serum leptin, total and acyl ghrelin were measured in addition to white blood cell (WBC) and lymphocyte counts. Results 25 patients received etanercept and 25 conventional therapies (including methotrexate) for JIA. There was no difference between treatment and control groups in leptin or ghrelin levels and no evidence of a relationship between leptin and ghrelin in patients with JIA...
April 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28412712/antitumor-necrosis-factor-%C3%AE-therapy-associated-with-inflammatory-bowel-disease-three-cases-and-a-systematic-literature-review
#11
Amir Bieber, Abdallah Fawaz, Irena Novofastovski, Reuven Mader
OBJECTIVE: Antitumor necrosis factor-α (anti-TNF-α) therapy is the most prescribed biologic agent therapy in rheumatology and gastroenterology. However, a number of serious side effects have been reported with these drugs. Only a handful of cases of new-onset inflammatory bowel disease (IBD), mostly in children diagnosed with juvenile idiopathic arthritis (JIA), have been reported during anti-TNF-α therapy. We present 3 cases of adult IBD following anti-TNF-α therapy and a literature review on this topic...
April 15, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28412076/original-article-varicella-vaccination-elicits-a-humoral-and-cellular-response-in-children-with-rheumatic-diseases-using-immune-suppressive-treatment
#12
Noortje Groot, Gecilmara Pileggi, Cleonice B Sandoval, Ingrid Grein, Guy Berbers, Virginia Paes Leme Ferriani, Nico Wulffraat, Sytze de Roock
OBJECTIVE: To assess humoral and cellular responses to live-attenuated varicella zoster virus (VZV) vaccination of patients with juvenile idiopathic arthritis (JIA), juvenile dermatomyositis (JDM) or juvenile scleroderma (JScle) compared to those of healthy controls (HC). METHODS: Before, 4-6weeks and one year after VZV vaccination, blood samples of patients and HC were collected. VZV-specific antibody concentrations were measured by ELISA and multiplex immune-assay...
April 12, 2017: Vaccine
https://www.readbyqxmd.com/read/28407779/histologic-effects-of-mandibular-protrusion-splints-in-antigen-induced-tmj-arthritis-in-rabbits
#13
Julia von Bremen, Kernt Köhler, Krystyna Siudak, Daniel Zahner, Sabine Ruf
BACKGROUND: Although it is common clinical practice to treat children with Juvenile Idiopathic Arthritis (JIA) with functional appliances, the scientific evidence for this is limited. The aim of this study was to study the histologic effects of mandibular protrusion splints in temporomandibular joint (TMJ) arthritis in rabbits. METHODS: Twenty-eight ten-week old New Zealand white rabbits were randomly divided into four groups: AO (TMJ arthritis, no splint), AS (TMJ arthritis, mandibular splint advancement), OS (no arthritis, mandibular splint advancement) and OO (no arthritis, no splint)...
April 13, 2017: Pediatric Rheumatology Online Journal
https://www.readbyqxmd.com/read/28405017/lectin-pathway-factors-in-patients-suffering-from-juvenile-idiopathic-arthritis
#14
Katarzyna Kasperkiewicz, Łukasz Eppa, Anna S Świerzko, Marcin A Bartłomiejczyk, Zbigniew M Żuber, Katarzyna Siniewicz-Luzeńczyk, Elżbieta Mężyk, Misao Matsushita, Leokadia Bąk-Romaniszyn, Krzysztof Zeman, Mikael Skurnik, Maciej Cedzyński
Both complement activation and certain infections (including those with Yersinia sp.) may contribute to the pathogenesis of juvenile idiopathic arthritis (JIA). We investigated factors specific for the lectin pathway of complement: mannose-binding lectin (MBL), ficolins and associated serine protease-2 (MASP-2), in 144 patients and 98 controls. 106 patients had oligoarticular disease and 38 had polyarticular disease. In 51 patients (out of 133 tested), Yersinia-reactive antibodies were found (JIA Ye+ group)...
April 13, 2017: Immunology and Cell Biology
https://www.readbyqxmd.com/read/28403864/health-related-quality-of-life-among-swedish-children-with-juvenile-idiopathic-arthritis-parent-child-discrepancies-gender-differences-and-comparison-with-a-european-cohort
#15
Veronica Lundberg, Catharina Eriksson
BACKGROUND: This study investigates gender differences in self-reports and between parent and child reports in Health-related Quality of Life (HRQOL), measured with disease-specific and generic instruments for chronic disease. Comparison of HRQOL results in this Juvenile Idiopathic Arthritis (JIA) sample to a European cohort of children with JIA and one of children with other health conditions are also made. METHODS: Fifty-three children with juvenile idiopathic arthritis (JIA), aged 8-18 years, and their parents completed the condition-specific DISABKIDS for JIA, and the DISABKIDS generic instrument for chronic conditions (DCGM-37) in a cross-sectional study...
April 12, 2017: Pediatric Rheumatology Online Journal
https://www.readbyqxmd.com/read/28402494/school-self-concept-in-adolescents-with-chronic-pain
#16
Deirdre E Logan, Laura S Gray, Christina N Iversen, Susan Kim
This study investigated school self-efficacy and sense of school membership (collectively "school self-concept") as potential influences on impaired school function among adolescents with chronic pain, including comparison of adolescents with primary pain to those with disease-based pain and pain-free peers.  In all, 264 adolescents (12-17 years old) with primary pain conditions, juvenile idiopathic arthritis, or no pain completed measures of functional disability, school functioning, pain characteristics, and school self-concept, the Self-Efficacy Questionnaire for School Situations (SEQ-SS), and Psychological Sense of School Membership (PSSM)...
April 11, 2017: Journal of Pediatric Psychology
https://www.readbyqxmd.com/read/28401744/fdg-pet-in-macrophage-activation-syndrome-associated-with-systemic-juvenile-idiopathic-arthritis
#17
Masaki Shimizu, Yasuhiro Ikawa, Mao Mizuta, Maiko Takakura, Natsumi Inoue, Ryosei Nishimura, Akihiro Yachie
We herein describe a case of systemic juvenile idiopathic arthritis (s-JIA)-associated macrophage activation syndrome (MAS) in which the (18F) fluorodeoxyglucose positron emission tomography ((18)(F) FDG-PET) findings were characteristic. The pattern of greater (18)(F) FDG accumulation into the spleen compared with the liver was more remarkable in this patient compared with s-JIA. This pattern, however, was also observed in cases of acute leukemia. In the present patient, serum interleukin (IL)-18 was extremely elevated (255 000 pg/mL), whereas in leukemia patients it is mildly elevated (360-1480 pg/mL)...
April 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28400731/il-1-inhibition-may-have-an-important-role-in-treating-refractory-kawasaki-disease
#18
REVIEW
Perrine Dusser, Isabelle Koné-Paut
Kawasaki disease (KD) is an acute inflammatory vasculitis occurring in young children before 5 years and representing at this age, the main cause of acquired heart disease. A single infusion of 2 g/kg of intravenous immunoglobulins along with aspirin has reduced the frequency of coronary artery aneurysms from 25 to 5%. However, 10-20% of patients do not respond to standard treatment and have an increased risk of cardiac complications and death. The development of more potent therapeutic approaches of KD is an urgent need...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28399931/pilot-study-comparing-the-childhood-arthritis-rheumatology-research-alliance-carra-systemic-juvenile-idiopathic-arthritis-consensus-treatment-plans
#19
Yukiko Kimura, Sriharsha Grevich, Timothy Beukelman, Esi Morgan, Peter A Nigrovic, Kelly Mieszkalski, T Brent Graham, Maria Ibarra, Norman Ilowite, Marisa Klein-Gitelman, Karen Onel, Sampath Prahalad, Marilynn Punaro, Sarah Ringold, Dana Toib, Heather Van Mater, Jennifer E Weiss, Pamela F Weiss, Laura E Schanberg
OBJECTIVES: To assess the feasibility of studying the comparative effectiveness of the Childhood Arthritis and Rheumatology Research Alliance (CARRA) consensus treatment plans (CTPs) for systemic Juvenile Idiopathic Arthritis (JIA) using an observational registry. METHODS: Untreated systemic JIA patients enrolled in the CARRA Registry were begun on one of 4 CTPs chosen by the treating physician and patient/family (glucocorticoid [GC] alone; methotrexate [MTX] ± GC; IL1 inhibitor [IL1i] ± GC; IL6 inhibitor [IL6i] ± GC)...
April 11, 2017: Pediatric Rheumatology Online Journal
https://www.readbyqxmd.com/read/28399930/radiographic-damage-in-hands-and-wrists-of-patients-with-juvenile-idiopathic-arthritis-after-29%C3%A2-years-of-disease-duration
#20
Anne M Selvaag, Eva Kirkhus, Lena Törnqvist, Vibke Lilleby, Hanne A Aulie, Berit Flatø
BACKGROUND: There are few studies on radiographic outcome after long-term disease duration in juvenile idiopathic arthritis (JIA). We wanted to evaluate 29-year radiographic outcome in hands/wrists and predictors of damage in patients with long-term active JIA. METHODS: Patients diagnosed from 1980 to 1985, who had active disease at 15-, 23- or 29-year follow-up and arthritis in the wrists during the disease course, were reexamined with radiographs of hands/wrists...
April 11, 2017: Pediatric Rheumatology Online Journal
keyword
keyword
12337
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"