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https://www.readbyqxmd.com/read/29441614/characterization-of-oily-mature-skin-by-biophysical-and-skin-imaging-techniques
#1
M O de Melo, P M B G Maia Campos
BACKGROUND: The skin is a complex biological system and may suffer change according to the environmental factors, as higher temperatures can increase sebum excretion, presenting oiliness and acne. These alterations can persist during the aging and provoke more changes in aged skin. In this study we evaluated the mature oily skin characteristics using biophysical and skin imaging techniques. MATERIAL AND METHODS: Sixty healthy female subjects, aged between 39 and 55 years old were recruited and separated into 2 groups according to their skin type: normal/dry and oily skin...
February 13, 2018: Skin Research and Technology
https://www.readbyqxmd.com/read/29441293/mucocutaneous-manifestations-in-patients-with-chronic-kidney-disease-a-cross-sectional-study
#2
Rattan S Rashpa, Vikram K Mahajan, Pankaj Kumar, Karaninder S Mehta, Pushpinder S Chauhan, Ritu Rawat, Vikas Sharma
Background: Chronic kidney disease (CKD)-associated mucocutaneous manifestations significantly impair the quality of life but often remain understudied. They may also vary across regions, socioeconomic and nutritional status, and racial differences. Objectives: To study the patterns of mucocutaneous disorders and their prevalence in CKD patients irrespective of clinical stage or dialysis status. Materials and Methods: 122 (M:F = 77:45) patients aged 21‒85 (Mean ± SD = 57...
January 2018: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/29440628/drug-reaction-with-eosinophilia-and-systemic-symptoms-dress-syndrome-secondary-to-furosemide-case-report-and-review-of-literature
#3
Jared James, Yasser M Sammour, Andrew R Virata, Terri A Nordin, Igor Dumic
BACKGROUND DRESS is a rare, life threatening syndrome that occurs following exposure to certain medications, most commonly antibiotics and antiepileptics. While sulfonamide antibiotics are frequently implicated as causative agents for DRESS syndrome, furosemide, a nonantibiotic sulfonamide, has not been routinely reported as the causative agent despite its widespread use. CASE REPORT A 63 year old male who started furosemide for lower extremity edema 10 weeks prior presented with diarrhea, fever of 39.4°C, dry cough and maculopapular rash involving >50% of his body...
February 14, 2018: American Journal of Case Reports
https://www.readbyqxmd.com/read/29438574/protective-effects-of-an-extract-of-the-freshwater-microalga-scenedesmus-rubescens-on-uv-irradiated-skin-cells
#4
Remo Campiche, Petra Sandau, Elke Kurth, Marco Massironi, Dominik Imfeld, Rolf Schuetz
BACKGROUND: Skin aging results from intrinsic but also extrinsic factors of which UV-irradiation is a main cause. It is hence of interest to have means to protect skin from UV -irradiation induced damage. We selected an extract of the freshwater microalga Scenedesmus rubescens and assessed its potential to protect skin from photoaging caused by UV-irradiation. METHODS: Skin cells in-vitro and ex-vivo were analyzed for markers of UV-irradiation induced photodamage such as decreased viability, decreased collagen content, hyperpigmentation, and sunburn cells...
February 13, 2018: International Journal of Cosmetic Science
https://www.readbyqxmd.com/read/29436214/three-dimensional-graphene-structure-for-healable-flexible-electronics-based-on-diels-alder-chemistry
#5
Jinhui Li, Qiang Liu, Derek Ho, Songfang Zhao, Shuwen Wu, Lei Ling, Fei Han, Xinxiu Wu, Guoping Zhang, Rong Sun, Ching-Ping Wong
Wearable electronics with excellent stretchability and sensitivity have emerged as a very promising field with wide applications such as e-skin and human motion detection. Although three-dimensional (3D) graphene structures (GS) have been reported for high performance strain sensors, challenges still remain such as the high cost of GS preparation, low stretchability, as well as the lack of ability to heal itself. In this paper, we reported a novel self-healing flexible electronic with 3D GS based on Diels-Alder (DA) chemistry...
February 13, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29435597/-hedgehog-fungi-in-a%C3%A2-dermatological-office-in-munich-case-reports-and-review
#6
REVIEW
A Kargl, B Kosse, S Uhrlaß, D Koch, C Krüger, K Eckert, P Nenoff
Patient 1: After contact to a central European hedgehog (Erinaceus europaeus), a 50-year-old female with atopy developed erythrosquamous tinea manus on the thumb and thenar eminence of the right hand. The patient had previously been scalded by hot steam at the affected site. The zoophilic dermatophyte Trichophyton erinacei could be cultured from the hedgehog as well as from scrapings from the woman's skin. Antifungal treatment of the hedgehog was initiated using 2 weekly cycles of itraconazole solution (0...
February 12, 2018: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/29428701/influence-of-glycosaminoglycans-on-the-properties-of-thin-films-based-on-chitosan-collagen-blends
#7
B Kaczmarek, A Sionkowska, J Skopinska-Wisniewska
Thin films based on chitosan, collagen, and glycosaminoglycans isolated from fish skin were obtained by solvent evaporation. The films were characterized by different analyses, e.g. surface free energy determination, swelling tests, roughness, mechanical and thermal measurements. Moreover, the degradation studies were carried out by the film treatment with collagenase. The results showed that the properties of the films based on chitosan and collagen can be modified by the glycosaminoglycans addition. It was noticed that the addition of glycosaminoglycans enhances the surface hydrophilicity and reduces surface free energy...
February 6, 2018: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29426737/-demodex-genus-colonizing-parasites-of-healthy-people-or-mites-associated-with-ocular-pathology
#8
Florencia Mongi, Laura Laconte, Rodolfo D Casero
Demodex folliculorum and Demodex brevis are mites that are responsible for human demodicosis affecting skin and frequently linked to ocular diseasess. The aim of this work was to determine the association between Demodex sp. and eyelid and eyelash diseases and to establish the predisposing factors for acquiring this parasitic disease. Eyelashes from symptomatic and asymptomatic patients (n=72) between 9 and 82 years old were analyzed, where 53% were positive for Demodex sp., of which 66% manifested ocular symptoms and pathologies, blepharitis and dry eye being prevalent...
February 6, 2018: Revista Argentina de Microbiología
https://www.readbyqxmd.com/read/29423165/surgical-management-of-digital-ischemia-caused-by-constriction-band-formation-in-a-patient-with-ichthyosis-vulgaris
#9
Tian Ran Zhu, Jonathan Bass, Scott Schmidt
Ichthyosis is a broad and loosely defined group of hereditary and acquired disorders characterized by filaggrin dysfunction and impaired epidermal homeostasis that results in dry, scaly and thickened skin. Individuals with truncation mutations in the profilaggrin gene coding for filaggrin are strongly predisposed to severe forms of ichthyosis. The phenotypical expression of ichthyosis caused by the same genotypical mutation can vary considerably in severity and in regards to how much constricting scar tissue develops...
September 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29421601/novel-contiguous-gene-deletion-in-peruvian-girl-with-trichothiodystrophy-type-4-and-glutaric-aciduria-type-3
#10
Jorge La Serna-Infantes, Miguel Chávez Pastor, Milana Trubnykova, Félix Chavesta Velásquez, Flor Vásquez Sotomayor, Hugo Abarca Barriga
Trichothiodystrophy type 4 is a rare autosomal recessive and ectodermal disorder, characterized by dry, brittle, sparse and sulfur-deficient hair and other features like intellectual disability, ichthyotic skin and short stature, caused by a homozygous mutation in MPLKIP gene. Glutaric aciduria type 3 is caused by a homozygous mutation in SUGCT gene with no distinctive phenotype. Both genes are localized on chromosome 7 (7p14). We report an 8-year-old female with short stature, microcephaly, development delay, intellectual disability and hair characterized for dark, short, coarse, sparse and brittle associated to classical trichorrhexis microscopy pattern...
February 5, 2018: European Journal of Medical Genetics
https://www.readbyqxmd.com/read/29417794/efficacy-of-a-detergent-combined-with-a-moisturiser-for-the-treatment-of-pruritus-associated-with-xerosis-in-an-elderly-population-affected-by-kaposi-s-sarcoma
#11
Athanasia Tourlaki, Giovanni Genovese, Dario Consonni, Lucia Brambilla
BACKGROUND: Xerosis is common among patients with Kaposi's sarcoma (KS). The aim of our study was to evaluate the efficacy of a detergent containing dihydroavenanthramide D 5% combined with a moisturiser containing 1% of menthol for the treatment of chronic pruritus associated with xerosis in elderly KS patients. METHODS: We conducted a prospective, open-label, intra-individual, right/left comparative study. During the 4-week treatment study, patients used the test products on the right lower limb, and a basic skin cleanser plus basic cream on their left lower limb, in a predefined protocol...
February 7, 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29405429/age-related-differences-in-the-functional-properties-of-lips-compared-with-skin
#12
E Tamura, J Ishikawa, K Sugata, K Tsukahara, H Yasumori, T Yamamoto
BACKGROUND/AIMS: Lips can easily become dry and rough and their biggest problems are drying and chapping. The cause of those problems is considered to be that the stratum corneum (SC) moisture is small and its barrier function is low. However, those problems decrease in subjects as they approach 40 years of age, after which problems due to their shape and color increase. The purpose of this study was to investigate relationships between SC properties of the lips during aging and to clarify the cause(s) of lip problems...
February 6, 2018: Skin Research and Technology
https://www.readbyqxmd.com/read/29402243/treatment-decisions-clinical-outcomes-and-pharmacoeconomics-in-the-treatment-of-patients-with-egfr-mutated-stage-iii-iv-nsclc-in-germany-an-observational-study
#13
Wolfgang Schuette, Peter Schirmacher, Wilfried E E Eberhardt, Manfred Dietel, Ute Zirrgiebel, Lars Muehlenhoff, Michael Thomas
BACKGROUND: We evaluated treatment decisions and outcomes in a cohort of predominately Caucasian patients with EGFR mutation-positive (EGFR Mut+) non-small-cell lung cancer (NSCLC). METHODS: REASON (NCT00997230) was a non-interventional study in German patients with stage IIIB/IV NSCLC. Secondary endpoints for EGFR Mut + NSCLC included progression-free survival (PFS), overall survival (OS), adverse event (AE) management, and pharmacoeconomic outcomes. RESULTS: Among 334 patients with EGFR Mut + NSCLC, tyrosine kinase inhibitors (TKIs) were the most common first-line therapy (56...
February 5, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29399651/ionotactile-stimulation-nonvolatile-ionic-gels-for-human-machine-interfaces
#14
Samuel E Root, Cody W Carpenter, Laure V Kayser, Daniel Rodriquez, Daniel M Davies, Shen Wang, Siew Ting M Tan, Ying Shirley Meng, Darren J Lipomi
We report the application of a nonvolatile ionic gel as a soft, conductive interface for electrotactile stimulation. Materials characterization reveals that, compared to a conventional ionic hydrogel, a glycerol-containing ionic gel does not dry out in air, has better adhesion to skin, and exhibits a similar impedance spectrum in the range of physiological frequencies. Moreover, psychophysical experiments reveal that the nonvolatile gel also exhibits a wider window of comfortable electrotactile stimulation...
January 31, 2018: ACS Omega
https://www.readbyqxmd.com/read/29397030/sensitive-skin-in-france-a-study-on-prevalence-relationship-with-age-and-skin-type-and-impact-on-quality-of-life
#15
L Misery, E Jourdan, F Huet, E Brenaut, B Cadars, S Virassamynaïk, M Sayag, C Taieb
BACKGROUND: Many epidemiological studies have been performed, but a potential increase in the prevalence of sensitive skin as well as its relationship with age and skin type and the impact of sensitive skin on quality of life are still debated. OBJECTIVE: TO ANSWER THESE UNRESOLVED QUESTIONS: METHODS: An opinion poll was conducted on a representative French 5000-person sample. RESULTS: Fifty-nine percent of the people declared very sensitive or fairly sensitive skin (together: sensitive skin), and women (66%) declared sensitive skin more frequently than men (51...
February 3, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29394674/-a-case-of-stage-iv-breast-cancer-with-extensive-metastasis-successfully-treated-with-s-1-plus-anastrozole-therapy
#16
Tatsuro Mugitani, Tomoya Hatakeyama, Toshinori Sakai, Atsushi Matsumura, Shiro Ogino, Toshikazu Akami, Shinji Okano
We report the case of a patient in which S-1 plus anastrozole was administered as first-line chemotherapy for Stage IV breast cancer with skin invasion, multiple lymph node metastasis, and lymphangitis carcinomatosis. A 77-year-old woman had a mass destroyed immediately outside the axilla with dry coughs. An 11mm unpalpable mass in the right breast and an axillary mass were confirmed to be scirrhous carcinoma(Luminal type B), respectively, by core needle biopsy. In one course, S- 1(100mg/day)therapy involves taking 2 courses of 14 days of administration and 7 days off the drug...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29392767/does-dietary-fluid-intake-affect-skin-hydration-in-healthy-humans-a-systematic-literature-review
#17
M Akdeniz, T Tomova-Simitchieva, G Dobos, U Blume-Peytavi, J Kottner
BACKGROUND: Associations between daily amounts of drinking water and skin hydration and skin physiology receive increasingly attention in the daily life and in clinical practice. However, there is a lack of evidence of dermatological benefits from drinking increased amounts of water. MATERIALS AND METHODS: Pubmed and Web of Science were searched without any restrictions of publication dates. References of included papers and related reviews were checked. Eligibility criteria were primary intervention and observational studies investigating the effects of fluid intake on skin properties in English, German, Spanish or Portuguese language, including subjects being healthy and 18+ years...
February 2, 2018: Skin Research and Technology
https://www.readbyqxmd.com/read/29391092/outcomes-of-unroofing-with-limited-excision-and-structured-postoperative-care-for-pilonidal-disease
#18
Farees Ricky Tavangari, Jennifer Amy Lee, David Garza, Talar Tejirian
Despite a wide variety of surgical techniques to treat chronic pilonidal disease, high rates of recurrence are common. The current study analyzes the outcome of unroofing with limited excision combined with structured postoperative wound care for pilonidal disease. We performed a retrospective review of all patients who were treated with this technique over a seven year period. Ninety-four patients aged 11 to 63 (mean age 26) received this treatment for pilonidal disease. Eighty-nine patients were treated for primary pilonidal disease and five were treated for recurrent disease after procedures such as flaps...
October 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/29389599/recent-developments-on-the-extraction-and-application-of-ursolic-acid-a-review
#19
REVIEW
Lucía López-Hortas, Patricia Pérez-Larrán, María Jesús González-Muñoz, Elena Falqué, Herminia Domínguez
Ursolic acid (UA) is a pentacyclic triterpenoid widely found in herbs, leaves, flowers and fruits; update information on the major natural sources or agro-industrial wastes is presented. Traditional (maceration, Soxhlet and heat reflux) and modern (microwave-, ultrasound-, accelerated solvent- and supercritical fluid) extraction and purification technologies of UA, as well as some patented process, are summarized. The great interest in this bioactive compound is related to the beneficial effects in human health due to antioxidant, antimicrobial, anti-inflammatory, hepatoprotective, immunomodulatory, anti-tumor, chemopreventive, cardioprotective, antihyperlipidemic and hypoglycemic activities, and others...
January 2018: Food Research International
https://www.readbyqxmd.com/read/29387518/effect-of-administrating-polysaccharide-from-black-currant-ribes-nigrum-l-on-atopic-dermatitis-in-nc-nga-mice
#20
Hiroshi Ashigai, Yuta Komano, Guanying Wang, Yasuji Kawachi, Kazuko Sunaga, Reiko Yamamoto, Ryoji Takata, Mika Miyake, Takaaki Yanai
Atopic dermatitis (AD) is a chronic inflammatory skin disease that causes dry skin and functional disruption of the skin barrier. AD is often accompanied by allergic inflammation. AD patient suffer from heavy itching, and their quality of life is severely affected. Some pharmaceuticals for AD have some side effects such as skin atrophy. So it is necessary to develop mild solutions such as food ingredients without side effects. There are various causes of AD. It is especially induced by immunological imbalances such as IFN-γ reduction...
2018: Bioscience of Microbiota, Food and Health
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