Elisete Isabel Crocco, Liliana Torloni, Paula Bonilha Fernandes, Maria Elisa Barbosa Bueno de Campos, Maura Gonzaga, Fernanda Cristina Silva, João Paulo Sardin Nasario, Lucas Offenbecker Guerra, Angélica Richart Csipak, Vivienne Carduz Castilho
BACKGROUND: Melasma is a chronic dermatosis that impacts the patient's quality of life and can present considerable challenges in terms of effective treatment. OBJECTIVE: To evaluate the effectiveness, tolerability, and safety of 5% cysteamine combined with 4% nicotinamide in female subjects with melasma. METHODS: This single-center, single-arm, prospective, open-label study evaluated patients with melasma using a combination cream of 5% cysteamine and 4% nicotinamide in a progressive regimen (60 min in the first month, 120 min in the second month, and 180 min in the third month)...
February 7, 2024: Journal of Cosmetic Dermatology