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https://www.readbyqxmd.com/read/28529420/long-pulsed-nd-yag-laser-and-intense-pulse-light-755-nm-for-idiopathic-facial-hirsutism-a-comparative-study
#1
Arpit Shrimal, Souvik Sardar, Soumyajit Roychoudhury, Somenath Sarkar
BACKGROUND: Hirsutism means excessive terminal hair growth in a female in male pattern distribution. Perception of hirsutism is subjective. Permanent laser hair reduction is a slow process taking many sessions and tracking of improvement parameters is tedious. Hence, a lot of confusion still exists regarding the type of laser most beneficial for treatment. AIM: The aim of this study was to compare the effectiveness and safety profile of long-pulsed Nd: YAG laser (1064 nm) and intense pulse light (IPL)-755 nm in management of idiopathic facial hirsutism...
January 2017: Journal of Cutaneous and Aesthetic Surgery
https://www.readbyqxmd.com/read/28528603/a-retrospective-study-of-multiple-sequential-light-and-laser-sources-to-activate-aminolevulinic-acid-in-the-treatment-of-acne-vulgaris
#2
Daniel P Friedmann, Mitchel P Goldman, Sabrina G Fabi, Isabella Guiha
Reports of the sequential use of multiple light and laser sources for topical 5-aminolevulinic acid (ALA) activation in photodynamic therapy (PDT) of inflammatory acne vulgaris are lacking. The authors sought to retrospectively compare field-directed ALA-PDT with blue light only, blue light + pulsed dye laser (PDL), blue light + intense pulsed light (IPL), blue light + PDL + IPL, or blue light + red light + PDL + IPL for inflammatory acne of the face or upper trunk. Results showed a trend toward greater patient-reported improvement with comparable tolerability using multiple, sequential light sources in ALA-PDT for acne vulgaris, albeit not statistically significant...
2017: Skinmed
https://www.readbyqxmd.com/read/28523237/evoked-potential-changes-in-patients-with-parkinson-s-disease
#3
Chunyan Liu, Yaping Zhang, Weiguo Tang, Binda Wang, Bona Wang, Songbin He
OBJECTIVE: Patients with Parkinson's disease (PD) may have sensory dysfunction, and it can be more easily demonstrated through electrophysiologic testing. We aimed to explore whether the impairment of brainstem visual and auditory passageway exists in PD patients using visual evoked potential (VEP) and brainstem auditory evoked potential (BAEP) examinations. METHODS: Forty-two PD cases and thirty controls participated in the study. All subjects underwent the VEP and BAEP examinations...
May 2017: Brain and Behavior
https://www.readbyqxmd.com/read/28522884/profiles-of-periglomerular-cells-in-the-olfactory-bulb-of-prokineticin-type-2-receptor-deficient-mice
#4
Atsuko Kubo, Mitsugu Sujino, Koh-Hei Masumoto, Atsuko Fujioka, Toshio Terashima, Yasufumi Shigeyoshi, Mamoru Nagano
Both prokineticin receptor 2 (pkr2) and prokineticin 2 (pk2) gene-deficient mice have hypoplasia of the main olfactory bulb (MOB). This hypoplasia has been attributed to disruption of the glomerulus that is caused by loss of afferent projection from olfactory sensory neurons (OSN), and to the impaired migration of granule cells, a type of interneuron. In the present study, we examined whether migration of the second type of interneuron, periglomerular cells (PGC), is dependent on the pkr2 expression by observing the localization of distinct subpopulations of PGC: calretinin (CR)-, calbindin (CB)- and tyrosine hydroxylase (TH)-expressing neurons...
April 27, 2017: Acta Histochemica et Cytochemica
https://www.readbyqxmd.com/read/28522658/effect-of-fontan-geometry-on-exercise-haemodynamics-and-its-potential-implications
#5
Elaine Tang, Zhenglun Alan Wei, Kevin K Whitehead, Reza H Khiabani, Maria Restrepo, Lucia Mirabella, James Bethel, Stephen M Paridon, Bradley S Marino, Mark A Fogel, Ajit P Yoganathan
OBJECTIVE: Exercise intolerance afflicts Fontan patients with total cavopulmonary connections (TCPCs) causing a reduction in quality of life. Optimising TCPC design is hypothesised to have a beneficial effect on exercise capacity. This study investigates relationships between TCPC geometries and exercise haemodynamics and performance. METHODS: This study included 47 patients who completed metabolic exercise stress test with cardiac magnetic resonance (CMR). Phase-contrast CMR images were acquired immediately following supine lower limb exercise...
May 18, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28496300/prospective-evaluation-of-intense-pulsed-light-and-meibomian-gland-expression-efficacy-on-relieving-signs-and-symptoms-of-dry-eye-disease-due-to-meibomian-gland-dysfunction
#6
Steven J Dell, Ronald N Gaster, Sheila C Barbarino, Derek N Cunningham
PURPOSE: The aim of this study was to estimate the efficacy of intense pulsed light (IPL), followed by meibomian gland expression (MGX), for reducing the number and severity of signs and symptoms of dry eye disease (DED) secondary to meibomian gland dysfunction (MGD). PATIENTS AND METHODS: In a prospective study conducted in two sites, 40 subjects (80 eyes) with moderate to severe MGD were enrolled. Major inclusion criteria consisted of at least two of the following measures being compatible with DED in both eyes: tear breakup time (TBUT), meibomian gland score (MGS), corneal fluorescein staining (CFS), Standard Patient Evaluation of Eye Dryness (SPEED) questionnaire, and tear film osmolarity (TFO)...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28493982/comparison-of-spectral-domain-optical-coherence-tomography-for-intra-retinal-layers-thickness-measurements-between-healthy-and-diabetic-eyes-among-chinese-adults
#7
Shu-Ting Li, Xiang-Ning Wang, Xin-Hua Du, Qiang Wu
PURPOSE: To compare intra-retinal layer thickness measurements between eyes with no or mild diabetic retinopathy (DR) and age-matched controls using Spectralis spectral-domain optical coherence tomography (SD-OCT). METHODS: Cross-sectional observational analysis study. High-resolution macular volume scans (30° * 25°) were obtained for 133 type 2 diabetes mellitus (T2DM) patients with no DR, 42 T2DM patients with mild DR and 115 healthy controls. The mean thickness was measured in all 9 Early Treatment Diabetic Retinopathy Study (ETDRS) sectors for 8 separate layers, inner retinal layer (IRL), outer retinal layer (ORL) and total retina (TR), after automated segmentation...
2017: PloS One
https://www.readbyqxmd.com/read/28485872/new-lasers-and-light-sources-old-and-new-risks
#8
REVIEW
Uwe Paasch, Antje Schwandt, Nikolaus Seeber, Gerd Kautz, Sonja Grunewald, Merete Haedersdal
Recent developments (new wavelengths, treatment concepts, and combinations) in the field of lasers, intense pulsed light (IPL), LED, as well as new energy and light sources have opened up new therapeutic options that extend beyond mere aesthetic indications. Thus, while fractional lasers used to be employed to merely treat wrinkles, the same devices - in the context of laser-assisted drug delivery - have now become important tools in the treatment of scars, field cancerization, and epithelial tumors. The requirements posed to physicians, both with respect to establishing the indication and conducting treatment, have been growing along with the increase in technological complexity as well as the rising number of comorbidities and comedications in a patient population that continues to age...
May 2017: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/28483062/immunocytochemical-localization-of-cholinergic-amacrine-cells-in-the-bat-retina
#9
Eun-Bee Park, Ya-Nan Gu, Chang-Jin Jeon
The purpose of this study was to localize the cholinergic amacrine cells, one of the key elements of a functional retina, in the retina of a microbat, Rhinolophus ferrumequinum. The presence and localization of choline acetyltransferase-immunoreactive (ChAT-IR) cells in the microbat retina were investigated using immunocytochemistry, confocal microscopy, and quantitative analysis. These ChAT-IR cells were present in the ganglion cell layer (GCL) and inner part of the inner nuclear layer (INL), as previously reported in various animals...
May 5, 2017: Acta Histochemica
https://www.readbyqxmd.com/read/28476336/abnormal-neural-activity-as-a-potential-biomarker-for-drug-naive-first-episode-adolescent-onset-schizophrenia-with-coherence-regional-homogeneity-and-support-vector-machine-analyses
#10
Yi Liu, Yan Zhang, Luxian Lv, Renrong Wu, Jingping Zhao, Wenbin Guo
BACKGROUND: Patients with adolescent-onset schizophrenia (AOS) hold the same but severe form of symptoms with adult-onset schizophrenia, and with worse outcome and poor treatment response to antipsychotics. Several dominant brain regions of schizophrenia patients show significantly abnormal structural and functional connectivity during resting-state scans. However, coherence regional homogeneity (Cohe-ReHo) in drug-naive first-episode patients with AOS remains unclear. METHOD: A total of 48 drug-naive first-episode AOS outpatients and 31 healthy controls underwent resting-state functional magnetic resonance scans...
May 2, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28474293/increased-arithmetic-complexity-is-associated-with-domain-general-but-not-domain-specific-magnitude-processing-in-children-a-simultaneous-fnirs-eeg-study
#11
Mojtaba Soltanlou, Christina Artemenko, Thomas Dresler, Florian B Haeussinger, Andreas J Fallgatter, Ann-Christine Ehlis, Hans-Christoph Nuerk
The investigation of the neural underpinnings of increased arithmetic complexity in children is essential for developing educational and therapeutic approaches and might provide novel measures to assess the effects of interventions. Although a few studies in adults and children have revealed the activation of bilateral brain regions during more complex calculations, little is known about children. We investigated 24 children undergoing one-digit and two-digit multiplication tasks while simultaneously recording functional near-infrared spectroscopy (fNIRS) and electroencephalography (EEG) data...
May 4, 2017: Cognitive, Affective & Behavioral Neuroscience
https://www.readbyqxmd.com/read/28472856/multiple-cell-types-form-the-vip-amacrine-cell-population
#12
Luis Pérez de Sevilla Müller, Alexander Solomon, Kristopher Sheets, Hinekura Hapukino, Allen Rodriguez, Nicholas C Brecha
Amacrine cells are a heterogeneous group of interneurons that form microcircuits with bipolar, amacrine and ganglion cells to process visual information in the inner retina. This study has characterized the morphology, neurochemistry and major cell types of a VIP-ires-Cre amacrine cell population. VIP-tdTomato and -Confetti (Brainbow2.1) mouse lines were generated by crossing a VIP-ires-Cre line with either a Cre-dependent tdTomato or Brainbow2.1 reporter line. Retinal sections and whole-mounts were evaluated by quantitative, immunohistochemical and intracellular labeling approaches...
May 4, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28467917/resting-state-functional-reorganization-in-parkinson-s-disease-an-activation-likelihood-estimation-meta-analysis
#13
REVIEW
Masoud Tahmasian, Simon B Eickhoff, Kathrin Giehl, Frank Schwartz, Damian M Herz, Alexander Drzezga, Thilo van Eimeren, Angela R Laird, Peter T Fox, Habibolah Khazaie, Mojtaba Zarei, Carsten Eggers, Claudia R Eickhoff
Parkinson's disease (PD) is a common progressive neurodegenerative disorder. Studies using resting-state functional magnetic resonance imaging (fMRI) to investigate underlying pathophysiology of motor and non-motor symptoms in PD yielded largely inconsistent results. This quantitative neuroimaging meta-analysis aims to identify consistent abnormal intrinsic functional patterns in PD across studies. We used PubMed to retrieve suitable resting-state studies and stereotactic data were extracted from 28 individual between-group comparisons...
April 8, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28466070/a-cre-mouse-line-for-probing-irradiance-and-direction-encoding-retinal-networks
#14
Shai Sabbah, Daniel Berg, Carin Papendorp, Kevin L Briggman, David M Berson
Cell type-specific Cre driver lines have revolutionized the analysis of retinal cell types and circuits. We show that the transgenic mouse Rbp4-Cre selectively labels several retinal neuronal types relevant to the encoding of absolute light intensity (irradiance) and visual motion. In the ganglion cell layer (GCL), most marked cells are wide-field spiking polyaxonal amacrine cells (ACs) with sustained irradiance-encoding ON responses that persist during chemical synaptic blockade. Their arbors spread about 1 mm across the retina and are restricted to the inner half of the ON sublamina of the inner plexiform layer (IPL)...
March 2017: ENeuro
https://www.readbyqxmd.com/read/28463045/mitigation-of-epidermal-growth-factor-receptor-inhibitor-induced-side-effects-utilizing-melanin-and-vascular-specific-lasers-a-case-report-series
#15
Karen Y Kuo, Bernice Kwong, Zakia Rahman
The advent of targeted chemotherapy has led to the emergence of new dermatologic toxicities. We sought to use lasers and light devices to treat recalcitrant cutaneous adverse effects related to cancer treatment. Three stage III or IV cancer patients with cutaneous complications due to epidermal growth factor receptor (EGFR) inhibitors were treated with melanin and vascular-specific laser and light technologies. Two patients reported reduction in papulopustular eruption following pulse dye laser (PDL) treatment...
March 2, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/28461015/diagnostic-accuracy-of-spectralis-sd-oct-automated-macular-layers-segmentation-to%C3%A2-discriminate-normal-from-early-glaucomatous-eyes
#16
Marta Pazos, Agnieszka Anna Dyrda, Marc Biarnés, Alicia Gómez, Carlos Martín, Clara Mora, Gianluca Fatti, Alfonso Antón
PURPOSE: To evaluate the accuracy of the macular retinal layer segmentation software of the Spectralis spectral-domain (SD) optical coherence tomography (OCT) device (Heidelberg Engineering, Inc., Heidelberg, Germany) to discriminate between healthy and early glaucoma (EG) eyes. DESIGN: Prospective, cross-sectional study. PARTICIPANTS: Forty EG eyes and 40 healthy controls were included. METHODS: All participants were examined using the standard posterior pole and the peripapillary retinal nerve fiber layer (pRNFL) protocols of the Spectralis OCT device...
April 28, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28452227/prediction-of-lignin-content-in-different-parts-of-sugarcane-using-near-infrared-spectroscopy-nir-ordered-predictors-selection-ops-and-partial-least-squares-pls
#17
Camila Assis, Rachel S Ramos, Lidiane A Silva, Volmir Kist, Márcio H P Barbosa, Reinaldo F Teófilo
The building of multivariate calibration models using near-infrared spectroscopy (NIR) and partial least squares (PLS) to estimate the lignin content in different parts of sugarcane genotypes is presented. Laboratory analyses were performed to determine the lignin content using the Klason method. The independent variables were obtained from different materials: dry bagasse, bagasse-with-juice, leaf, and stalk. The NIR spectra in the range of 10 000-4000 cm(-1) were obtained directly for each material. The models were built using PLS regression, and different algorithms for variable selection were tested and compared: iPLS, biPLS, genetic algorithm (GA), and the ordered predictors selection method (OPS)...
January 1, 2017: Applied Spectroscopy
https://www.readbyqxmd.com/read/28448294/macular-ganglion-cell-and-retinal-nerve-fiber-layer-thickness-in-children-with-refractive-errors-an-optical-coherence-tomography-study
#18
Jody P Goh, Victor Koh, Yiong Huak Chan, Cheryl Ngo
PURPOSE: To study the distribution of macular ganglion cell-inner plexiform layer (GC-IPL) thickness and peripapillary retinal nerve fiber layer (RNFL) thickness in children with refractive errors. MATERIALS AND METHODS: Two hundred forty-three healthy eyes from 139 children with refractive error ranging from -10.00 to +5.00 D were recruited from the National University Hospital Eye Surgery outpatient clinic. After a comprehensive ocular examination, refraction, and axial length (AL) measurement (IOLMaster), macular GC-IPL and RNFL thickness values were obtained with a spectral domain Cirrus high definition optical coherence tomography system (Carl Zeiss Meditec Inc...
April 26, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28447589/neuroretinal-evaluation-using-optical-coherence-tomography-in-patients-affected-by-pituitary-tumors
#19
Yasar Altun, Ayse Sevgi Karadag, Seyho Cem Yucetas, Sadullah Saglam, A Z A Tak, Ilhan Cag, Yusuf Ehi
AIM: To investigate the thickness of the retinal nerve fiber layer (RNFL), the ganglion cell layer (GCL), inner plexiform layer (IPL), and choroid thickness (CT) in patients with pituitary tumours, microadenoma and macroadenoma, using spectral optical coherence tomography (OCT). METHODS: Thirty six patients who had micro and macroadenoma, and 34 healthy participants (control group) were included in the study. Spectral OCT was used to measure the RNFL, GCL, IPL, and CT values for all patients...
2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/28439729/macular-morphology-in-former-preterm-and-full-term-infants-aged-4-to-10%C3%A2-years
#20
Achim Fieß, Johannes Janz, Alexander K Schuster, Ruth Kölb-Keerl, Markus Knuf, Bernd Kirchhof, Philipp S Muether, Jacqueline Bauer
OBJECTIVE: To analyse macular retinal and choroidal layer thickness in former preterm and full-term infants and to assess associated perinatal influence factors and functional correlation. METHODS: This prospective controlled, cross-sectional, hospital-based study in a tertiary center of maximum care examined former preterm infants with a gestational age (GA) ≤ 32 weeks and full-term neonates currently aged 4 to 10 years. We investigated data from 397 infants, analysing total foveal retinal thickness and six distinct macular retinal layer and choroidal layer measurements via spectral-domain optical coherence tomography...
April 25, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
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