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Menopause hot flashes

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https://www.readbyqxmd.com/read/29332222/efficacy-of-crocus-sativus-saffron-in-treatment-of-major-depressive-disorder-associated-with-post-menopausal-hot-flashes-a-double-blind-randomized-placebo-controlled-trial
#1
Ladan Kashani, Sophia Esalatmanesh, Farzaneh Eftekhari, Samrand Salimi, Tahereh Foroughifar, Farnaz Etesam, Hamideh Safiaghdam, Ehsan Moazen-Zadeh, Shahin Akhondzadeh
PURPOSE: Due to concerns regarding the side effects of hormone therapy, many studies have focused on the development of non-hormonal agents for treatment of hot flashes. The aim of this study was to evaluate the efficacy and safety of saffron (stigma of Crocus sativus) in treatment of major depressive disorder associated with post-menopausal hot flashes. METHODS: Sixty women with post-menopausal hot flashes participated in this study. The patients randomly received either saffron (30 mg/day, 15 mg twice per day) or placebo for 6 weeks...
January 13, 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29290208/quality-of-life-among-postmenopausal-women-enrolled-in-the-minnesota-green-tea-trial
#2
Allison Dostal Webster, Deborah A Finstad, Mindy S Kurzer, Carolyn J Torkelson
BACKGROUND: Postmenopausal symptomatology has not been elucidated in large, long-term human clinical trials. Our objective was to measure quality of life in postmenopausal women aged 50-70 years. METHODS: A Menopause-Specific Quality of Life-Intervention (MENQOL) questionnaire was completed by women enrolled in the Minnesota Green Tea Trial (n=932) to assess vasomotor, physical, sexual, and psychosocial symptoms in the years following menopause. Responses were coded; mean overall and domain scores ranged from 1 to 8...
February 2018: Maturitas
https://www.readbyqxmd.com/read/29231429/-comparison-between-manual-acupuncture-and-electroacupuncture-for-hot-flashes-and-sex-hormone-of-perimenopausal-syndrome
#3
Zhiliang Cao, Jian Tang, Yuting Xue, Qiong Wang, Saiqun Li, Youjun Zhou, Wei Zhang
OBJECTIVE: To compare the effect and differences sex the influence of hormone levels of perimenopau-sal syndrome patients between manual acupuncture and electroacupuncture (EA). METHODS: A total of 50 cases with perimenopausal syndrome were randomly assigned into an manual acupuncture group (27 cases) and an EA group (23 cases), and 1 case dropped in the EA group. The acupoints in the two groups were Guanyuan (CV 4), Zigong (EX-CA 1), Tianshu (ST 25), and Sanyinjiao (SP 6)...
March 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29230660/dietary-intake-of-soy-and-cruciferous-vegetables-and-treatment-related-symptoms-in-chinese-american-and-non-hispanic-white-breast-cancer-survivors
#4
Sarah J O Nomura, Yi-Ting Hwang, Scarlett Lin Gomez, Teresa T Fung, Shu-Lan Yeh, Chiranjeev Dash, Laura Allen, Serena Philips, Leena Hilakivi-Clarke, Yun-Ling Zheng, Judy Huei-Yu Wang
PURPOSE: This project was undertaken to examine the association between dietary intake of soy or cruciferous vegetables and breast cancer treatment-related symptoms among Chinese-American (CA) and Non-Hispanic White (NHW) breast cancer survivors. METHODS: This cross-sectional study included 192 CA and 173 NHW female breast cancer survivors (stages 0-III, diagnosed between 2006 and 2012) recruited from two California cancer registries, who had completed primary treatment...
December 11, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29221848/menopausal-related-symptoms-in-women-one-year-after-breast-cancer-surgery
#5
Melissa Mazor, Kathryn Lee, Anand Dhruva, Janine K Cataldo, Steven M Paul, Michelle Melisko, Betty J Smoot, Jon D Levine, Charles Elboim, Yvette P Conley, Christine Miaskowksi
CONTEXT: Approximately 60% to 100% of women with breast cancer experience at least one menopausal-related symptom. Little is known about associations between menopausal status and symptoms in women 12 months after breast cancer surgery. OBJECTIVE: Purpose of this study was to evaluate for differences in occurrence, severity, and distress of symptoms between pre- and post-menopausal women 12 months after breast cancer surgery. METHODS: Women with breast cancer (n=327) completed the Menopausal Symptoms Scale, that evaluated the occurrence, severity, and distress of 46 common menopausal-related symptoms...
December 5, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/29207728/the-effect-of-soy-isoflavones-on-the-menopause-rating-scale-scoring-in-perimenopausal-and-postmenopausal-women-a-pilot-study
#6
Marya Ahsan, Ayaz Khurram Mallick
Introduction: Menopause is associated with many unpleasant symptoms which vary in different phases of menopausal transition. Although, Hormone Replacement Therapy (HRT) is considered the most effective mode of treatment for these symptoms, its use is associated with increased risk of breast cancer, endometrial cancer and thromboembolic events. Soy isoflavones are being widely used as a safer alternative to HRT, even though scientific evidence of their efficacy is poor or lacking. Aim: To study the effect of soy isoflavone supplementation on the menopausal symptoms in perimenopausal and postmenopausal women...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/29206774/associations-between-improvement-in-genitourinary-symptoms-of-menopause-and-changes-in-the-vaginal-ecosystem
#7
Caroline M Mitchell, Sujatha Srinivasan, Anna Plantinga, Michael C Wu, Susan D Reed, Katherine A Guthrie, Andrea Z LaCroix, Tina Fiedler, Matthew Munch, Congzhou Liu, Noah G Hoffman, Ian A Blair, Katherine Newton, Ellen W Freeman, Hadine Joffe, Lee Cohen, David N Fredricks
OBJECTIVE: The aim of the study was to identify associations between improvement in genitourinary symptoms of menopause (GSM) and vaginal microbiota, vaginal glycogen, and serum estrogen. METHODS: Thirty postmenopausal women enrolled in a hot flash treatment trial (oral estradiol vs venlafaxine vs placebo) who reported GSM and provided vaginal swabs at 0, 4, and 8 weeks were studied. Bacterial communities were characterized using deep sequencing targeting the 16S rRNA gene V3-V4 region...
December 4, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29206771/vasomotor-symptom-characteristics-are-they-risk-factors-for-incident-diabetes
#8
Kristen E Gray, Jodie G Katon, Erin S LeBlanc, Nancy F Woods, Lori A Bastian, Gayle E Reiber, Julie C Weitlauf, Karin M Nelson, Andrea Z LaCroix
OBJECTIVE: Vasomotor symptoms (VMS), encompassing hot flashes and night sweats, may be associated with diabetes, but evidence is limited. We sought to estimate these associations. METHODS: Among 150,007 postmenopausal Women's Health Initiative participants from 1993 to 2014, we prospectively examined associations of incident diabetes with VMS characteristics at enrollment: any VMS, severity (mild/ moderate/severe), type (hot flashes/night sweats), timing (early [premenopausal or perimenopausal]/late [postmenopausal]), and duration...
December 4, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29200839/prediction-of-risk-of-depressive-symptoms-in-menopausal-women-based-on-hot-flash-and-sweating-symptoms-a-multicentre-study
#9
Yanwei Zheng, Yibei Zhou, Jiangshan Hu, Jieping Zhu, Qi Hua, Minfang Tao
Objective: The present study aimed to develop a symptom-based (namely, hot flashes and sweating) scoring system for predicting the risk of depressive symptoms in menopausal women via a multicentre cross-sectional survey. Methods: The data examined in the present study were obtained from 1,004 women aged 40-60 years who underwent physical examination at A Hospital. The basic information was obtained using a questionnaire-based survey. A self-rating depression scale was used to obtain the depressive symptom scores, while the Kupperman Menopausal Index was used to obtain the scores for the frequency of hot flashes and sweating...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29193539/comprehensive-evaluation-of-the-role-of-soy-and-isoflavone-supplementation-in-humans-and-animals-over-the-past-two-decades
#10
REVIEW
Yunqi Xiao, Shan Zhang, Haibing Tong, Shourong Shi
Soy and soy-based foods are considered healthy, particularly in many Asia-Pacific countries, where soy products have long been consumed. Soy and soy-related products have been found to help prevent the occurrence of cardiovascular diseases and certain types of cancer, such as breast and prostate cancer. These products can also have antioxidative effects that alleviate hot flashes during menopause and bone loss. These biological and therapeutic functions are primarily due to the isoflavones derived from soy, whose structure is similar to the structure of 17-β-oestradiol...
November 29, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29165623/effects-of-pharmacologic-and-nonpharmacologic-interventions-on-insomnia-symptoms-and-subjective-sleep-quality-in-women-with-hot-flashes-a-pooled-analysis-of-individual-participant-data-from-4-msflash-trials
#11
Katherine A Guthrie, Joseph C Larson, Kristine E Ensrud, Garnet L Anderson, Janet S Carpenter, Ellen W Freeman, Hadine Joffe, Andrea Z LaCroix, JoAnn E Manson, Charles M Morin, Katherine M Newton, Julie Otte, Susan D Reed, Susan M McCurry
Study Objectives: The Menopause Strategies: Finding Lasting Answers for Symptoms and Health network conducted three randomized clinical trials (RCT) testing six interventions treating vasomotor symptoms (VMS), and also collected self-reported sleep outcomes. A fourth RCT assessed an intervention for insomnia symptoms among women with VMS. We describe these seven interventions' effects relative to control in women with comparably severe insomnia symptoms and VMS. Methods: We analyzed pooled individual-level data from 546 peri- and postmenopausal women with Insomnia Severity Index (ISI) >12, and ≥14 bothersome VMS/week across the four RCTs...
November 20, 2017: Sleep
https://www.readbyqxmd.com/read/29156534/effects-of-standardized-isopropanolic-black-cohosh-and-estrogen-on-salivary-function-in-ovariectomized-rats
#12
Shuya Liu, Kaiyu Niu, Yunmeng Da, Yao Liu, Jing Zhang, Wenjuan Wang, Yi Zhang, Hai Jiang, Ke Wang, Wenpei Bai, Lihua Qin, Jing Jia
Oral dryness is a common feature in menopausal women. Estrogen therapy can relieve this symptom; however, the underlying mechanism was not clear. Standardized isopropanolic black cohosh (Actaea racemosa; Remifemin) can also relieve menopausal symptoms, such as hot flashes and sweating. Our previous study showed that standardized isopropanolic black cohosh could protect the submandibular gland structure. To investigate the effects and possible mechanisms of action of estrogen and standardized isopropanolic black cohosh on submandibular gland function in ovariectomized (OVX) rats, we measured body weight, daily water consumption, and blood flow in the submandibular glands...
November 15, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29077767/expectancy-after-the-first-treatment-and-response-to-acupuncture-for-menopausal-hot-flashes
#13
Carolyn C Ee, Sharmala Thuraisingam, Marie V Pirotta, Simon D French, Charlie C Xue, Helena J Teede
BACKGROUND: Evidence on the impact of expectancy on acupuncture treatment response is conflicting. OBJECTIVES: This secondary analysis of a randomized sham-controlled trial on acupuncture for menopausal hot flashes investigated whether treatment expectancy score was associated with hot flash score at end-of-treatment. Secondary analyses investigated whether there were associations between other pre-specified factors and hot flash score. STUDY DESIGN: Women experiencing moderately-severe hot flashes were randomized to receive 10 sessions of real or sham acupuncture over eight weeks...
2017: PloS One
https://www.readbyqxmd.com/read/29069110/vortioxetine-for-major-depressive-disorder-vasomotor-and-cognitive-symptoms-associated-with-the-menopausal-transition
#14
Marlene P Freeman, Laura J Cheng, Danna Moustafa, Abigail Davies, Alexandra Z Sosinsky, Betty Wang, Laura F Petrillo, Charlotte Hogan, Lee S Cohen
BACKGROUND: In a preliminary trial, we assessed the efficacy of vortioxetine for major depressive disorder (MDD) during the menopausal transition. Secondary outcomes included hot flashes (HFs), anxiety, and cognitive complaints. METHODS: Perimenopausal and early postmenopausal women with MDD (N = 27) received 8 weeks of open-label, flexible-dose treatment with vortioxetine. The Montgomery-Åsberg Depression Rating Scale (MADRS) was the primary outcome measure. Secondary measures included: HF frequency, the Greene Climacteric Scale (GCS), Menopause-Specific Quality of Life Questionnaire (MEN-QOL), Beck Anxiety Inventory (BAI), Cognitive and Physical Functioning Questionnaire (CPFQ), Digit Symbol Substitution Test (DSST), and Cogstate testing...
November 2017: Annals of Clinical Psychiatry: Official Journal of the American Academy of Clinical Psychiatrists
https://www.readbyqxmd.com/read/29067142/intermittent-96-hour-auricular-electroacupuncture-for-hot-flashes-in-patients-with-prostate-cancer-a-pilot-study
#15
Tyvin Rich, Gerald W Porter, Luisel Ricks-Santi, Tzvi Milshtein, Thomas Corbin
Objective: The hot flash is a common vasomotor disorder that causes distress in menopausal women and that can be debilitating in men with prostate cancer who are treated with androgen deprivation therapy (ADT). The utility of auricular electroacupuncture (AEA) was tested exclusively for a small cohort of men with ADT-induced vasomotor symptoms while the men underwent a course of curative radiotherapy. Materials and Methods: Prior to and during radiotherapy treatment, men with vasomotor symptoms were given repeated questionnaires regarding severity and frequency of hot flashes, quality of life (QoL), and sleep over a 6-week span of an AEA protocol...
October 1, 2017: Medical Acupuncture
https://www.readbyqxmd.com/read/29063390/comparison-of-quality-of-life-between-2-year-and-3-or-more-year-administration-of-leuprorelin-acetate-every-3-months-depot-in-combination-with-tamoxifen-as-adjuvant-endocrine-treatment-in-premenopausal-patients-with-endocrine-responsive-breast-cancer-a-randomized
#16
Yasuo Ohashi, Eiichi Shiba, Hiroko Yamashita, Junichi Kurebayashi, Shinzaburo Noguchi, Hirotaka Iwase, Michihiro Yoshida, Tsukasa Fujimoto
BACKGROUND: We conducted an open-label, randomized controlled trial evaluating the appropriate treatment duration of leuprorelin acetate 3-month depot, TAP-144-SR (3M), administered postsurgically every 3 months for 2 years versus 3 or more (up to 5) years, in combination with tamoxifen, for 5 years in premenopausal endocrine-responsive breast cancer patients and reported similar survival benefit in the two treatment groups. We hereby present patient-reported quality of life (QOL) data obtained from this trial...
October 24, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29062032/association-between-pulse-wave-velocity-and-hot-flashes-sweats-in-middle-aged-women
#17
Ruwei Yang, Yang Zhou, Changbin Li, Minfang Tao
As women age and go through menopause, they suffer a higher incidence of cardiovascular morbidity and mortality. Previous studies have shown that a relationship exists between hot flashes/sweats and an increased risk of cardiovascular disease. However, the association between hot flashes/sweats and arterial stiffness is unclear. We aim to explore the relationship between hot flashes/sweats and arterial stiffness using the modified Kupperman index (KMI) questionnaire and measure the brachial-ankle pulse wave velocity (baPWV)...
October 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28975316/review-in-menopause-intact-uterus-estrogen-progestogen-isoflavones-and-black-cohosh-reduce-hot-flashes
#18
Dennis G Maki
No abstract text is available yet for this article.
September 19, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28945634/influence-of-menopausal-status-on-the-symptom-experience-of-women-before-breast-cancer-surgery
#19
Melissa Mazor, Janine K Cataldo, Kathryn Lee, Anand Dhruva, Steven M Paul, Betty J Smoot, Laura B Dunn, Jon D Levine, Judy Mastick, Yvette P Conley, Christine Miaskowski
BACKGROUND: Breast cancer treatments can change women's hormonal milieu and alter their symptom experience. Little is known about associations between menopausal status and menopausal symptoms in women with breast cancer before surgery. OBJECTIVE: The purpose of this study was to evaluate for differences in occurrence, severity, and distress of symptoms between premenopausal and postmenopausal women before breast cancer surgery. METHODS: A total of 312 women with breast cancer completed the Menopausal Symptoms Scale, a self-report measure that evaluated the occurrence, severity, and distress of 46 common symptoms associated with menopause...
September 23, 2017: Cancer Nursing
https://www.readbyqxmd.com/read/28930222/add-on-complementary-medicine-in-cancer-care-evidence-in-literature-and-experiences-of-integration
#20
REVIEW
Elio Rossi, Mariella Di Stefano, Fabio Firenzuoli, Maria Valeria Monechi, Sonia Baccetti
Background: According to the literature an increasing number of cancer patients demand for complementary therapies during their disease. Research has demonstrated that some of these therapies are effective and safe as adjunctive treatments in specific symptoms of these patients. Methods: The aims of the paper are to review the main and recent papers of international literature on the effectiveness of complementary medicine (CM) therapies on side effects of anti-cancer protocols and improvement in the quality of life of oncological patients, and to describe the integration of evidence-based acupuncture, herbal medicine and homeopathy treatments in Public Cancer Network of the region of Tuscany...
January 24, 2017: Medicines (Basel, Switzerland)
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