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Menopause hot flashes

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https://www.readbyqxmd.com/read/28719420/the-bidirectional-relationship-between-vasomotor-symptoms-and-depression-across-the-menopausal-transition-a-systematic-review-of-longitudinal-studies
#1
Rifani B Natari, Alexandra M Clavarino, Treasure M McGuire, Kaeleen D Dingle, Samantha A Hollingworth
OBJECTIVE: To explore the nature of the bidirectional relationship between vasomotor symptoms (VMS) and depression, and to determine whether hot flashes and night sweats differentially affect the association between VMS and depression through their effect on sleep disruption. METHODS: Multiple databases were searched from 1961 until July 31, 2016, and a manual search of reference lists of identified articles was conducted. Sixteen articles that involved 10,008 participants were identified and analyzed...
July 17, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28706550/effect-of-acupressure-on-early-complications-of-menopause-in-women-referring-to-selected-health-care-centers
#2
Maryam Armand, Gity Ozgoli, Reza Heshmat Giti, Hamid Alavi Majd
BACKGROUND: Menopausal period is accompanied by numerous disorders and complications. Nowadays, hormone therapy is the most effective existing method to treat these complications, but many women cannot undergo that due to the known potentiality of risk. So, the present study aimed to investigate the effect of acupressure on early complications of menopause. MATERIALS AND METHODS: This is a blind random clinical trial conducted on 70 menopaused women referring to selected health care centers in Tehran who were qualified to enter the study...
May 2017: Iranian Journal of Nursing and Midwifery Research
https://www.readbyqxmd.com/read/28649145/do-ssris-and-snris-reduce-the-frequency-and-or-severity-of-hot-flashes-in-menopausal-women
#3
Chris Stubbs, Lisa Mattingly, Steven A Crawford, Elizabeth A Wickersham, Jessica L Brockhaus, Laine H McCarthy
CLINICAL QUESTION: In menopausal women who experience regular hot flashes, does treatment with selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs) reduce the frequency and/or severity of hot flashes? ANSWER: Yes. Review of the literature suggests that treatment with SSRIs or SNRIs reduces the frequency and severity of hot flashes in menopausal and post-menopausal women. Studies demonstrated that paroxetine (Paxil), citalopram (Celexa) and escitolapram (Lexapro) were the most effective SSRIs, and venlafaxine (Effexor) was the most effective first line SNRI, with desvenlafaxine as a second option...
May 2017: Journal of the Oklahoma State Medical Association
https://www.readbyqxmd.com/read/28640159/transcranial-direct-current-stimulation-effects-on-menopausal-vasomotor-symptoms
#4
Mônia Steigleder Bianchi, Charles Francisco Ferreira, Felipe Fregni, Pedro Schestatsky, Wolnei Caumo, Maria Celeste Osório Wender
OBJECTIVE: To assess the effects of transcranial direct current stimulation (tDCS) compared with tDCS-sham on vasomotor symptoms of postmenopausal women. METHODS: Postmenopausal women (N = 30), aged between 45 and 68 years, with at least four episodes of vasomotor symptoms per day, were recruited from a specialized outpatient clinic at a tertiary hospital in the south of Brazil and through a media call after inclusion and exclusion criteria were ensured. Active and tDCS-sham were administered over the motor cortex position (anode electrode) and contralateral supraorbital region (cathode electrode) for 10 consecutive days, except weekends...
June 19, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28640154/vaginal-microbiota-and-genitourinary-menopausal-symptoms-a-cross-sectional-analysis
#5
Caroline M Mitchell, Sujatha Srinivasan, Xiang Zhan, Michael C Wu, Susan D Reed, Katherine A Guthrie, Andrea Z LaCroix, Tina Fiedler, Matthew Munch, Congzhou Liu, Noah G Hoffman, Ian A Blair, Katherine Newton, Ellen W Freeman, Hadine Joffe, Lee Cohen, David N Fredricks
OBJECTIVE: To examine associations between the composition of the vaginal microbiota and genitourinary menopausal symptoms, serum estrogen, and vaginal glycogen. METHODS: For this cross-sectional study, 88 women aged 40 to 62 years, enrolled in a hot flash treatment trial, provided vaginal swabs and a blood sample at enrollment. Bacterial communities were characterized using 16S rRNA PCR and deep sequencing targeting the V3-V4 region. Quantities of Lactobacillus crispatus and Lactobacillus iners were measured using qPCR...
June 19, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28584559/schisandrae-fructus-reduces-symptoms-of-4-vinylcyclohexene-diepoxide-induced-ovarian-failure-in-mice
#6
Dasom Shin, Jinhee Ha, Seong Bin Hong, Geun-Hyung Kang, Deok-Sang Hwang, Hyunsu Bae
Menopause is associated with a decrease in the level of sex hormones such as ovarian estradiol and progesterone and can cause various symptoms such as depression, hot flash, fatigue, heart palpitations, and headache. Furthermore, there is a risk of developing complications such as osteoporosis, cardiovascular diseases, Alzheimer's disease, and ovarian cancer. Schisandrae Fructus (SF) is widely used in Korean medicine as a cure for such complications. This study was conducted to evaluate the therapeutic effects of SF against menopause symptoms associated with follicle depletion caused by the industrial chemical 4-vinylcyclohexene diepoxide (VCD) in mice...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28562488/does-obesity-increase-the-risk-of-hot-flashes-among-midlife-women-a-population-based-study
#7
Sylvio Saccomani, Jeffrey Frederico Lui-Filho, Cassia Raquel Juliato, Jose Roberto Gabiatti, Adriana Orcesi Pedro, Lucia Costa-Paiva
OBJECTIVE: To evaluate the association between vasomotor symptoms and obesity in climacteric women. METHODS: We conducted a cross-sectional population-based study of 749 women aged 45 to 60 years. The dependent variable was intensity of menopausal symptoms evaluated by the menopause rating scale questionnaire. Independent variables were sociodemographic and clinical characteristics, and obesity evaluated by body mass index. RESULTS: There was no significant difference in the majority of clinical and sociodemographic characteristics between the body mass index groups...
May 29, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28546818/investigating-the-relationship-between-sexual-function-and-quality-of-life-in-menopausal-women
#8
Masumeh Ghazanfarpour, Talat Khadivzadeh, Masaudeh Babakhanian
Objective: To evaluate the symptoms of menopausal women and the link between sexual function, menopausal symptoms and demographic variables. Materials and methods: This is a cross-sectional study in which 202 postmenopausal women admitted to the health care centers were selected. The Female Sexual Function Index (FSFI) questionnaire and Menopause-Specific Quality of Life (MENQOL) were the main means of data gathering. Results: The results of our study suggested that suggested that women experienced a number of menopausal symptoms such hot flash, headache and neck pains, reduced physical strength weight gain, pain or leg cramps, intensified sexual problem than women who lack such symptoms...
December 2016: Journal of Family & Reproductive Health
https://www.readbyqxmd.com/read/28538600/topical-geospatial-and-temporal-diffusion-of-the-2015-north-american-menopause-society-position-statement-on-nonhormonal-management-of-vasomotor-symptoms
#9
Janet S Carpenter, Tei Laine, Blake Harrison, Meghan LePage, Taran Pierce, Nathan Hoteling, Katy Börner
OBJECTIVE: We sought to depict the topical, geospatial, and temporal diffusion of the 2015 North American Menopause Society position statement on the nonhormonal management of menopause-associated vasomotor symptoms released on September 21, 2015, and its associated press release from September 23, 2015. METHODS: Three data sources were used: online news articles, National Public Radio, and Twitter. For topical diffusion, we compared keywords and their frequencies among the position statement, press release, and online news articles...
May 22, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28509814/validity-cut-points-and-minimally-important-differences-for-two-hot-flash-related-daily-interference-scales
#10
Janet S Carpenter, Giorgos Bakoyannis, Julie L Otte, Chen X Chen, Kevin L Rand, Nancy Woods, Katherine Newton, Hadine Joffe, JoAnn E Manson, Ellen W Freeman, Katherine A Guthrie
OBJECTIVES: To conduct psychometric analyses to condense the Hot Flash-Related Daily Interference Scale (HFRDIS) into a shorter form termed the Hot Flash Interference (HFI) scale; evaluate cut-points for both scales; and establish minimally important differences (MIDs) for both scales. METHODS: We analyzed baseline and postrandomization patient-reported data pooled across three randomized trials aimed at reducing vasomotor symptoms (VMS) in 899 midlife women. Trials were conducted across five MsFLASH clinical sites between July 2009 and October 2012...
May 15, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28489562/incidence-of-menopausal-symptoms-in-postmenopausal-breast-cancer-patients-treated-with-aromatase-inhibitors
#11
Dongsheng Hong, Ling Bi, Jun Zhou, Yinghui Tong, Qingwei Zhao, Jing Chen, Xiaoyang Lu
Aromatase inhibitors (AIs) are the standard of care for postmenopausal women with estrogen receptor-positive breast cancer. Here, we performed a meta-analysis to evaluate the occurrence of menopausal symptoms in breast cancer patients receiving the AI therapy. Patients treated with AIs had an increased risk of all-grade arthralgia (1.63 [95% CI: 1.34-1.98]) and insomnia (1.24 [95% CI: 1.14-1.34]). The overall incidence of hot flashes, fatigue, arthralgia, sweating, and insomnia in patients receiving AIs was 30...
June 20, 2017: Oncotarget
https://www.readbyqxmd.com/read/28488202/autonomic-control-of-body-temperature-and-blood-pressure-influences-of-female-sex-hormones
#12
REVIEW
Nisha Charkoudian, Emma C J Hart, Jill N Barnes, Michael J Joyner
Female reproductive hormones exert important non-reproductive influences on autonomic regulation of body temperature and blood pressure. Estradiol and progesterone influence thermoregulation both centrally and peripherally, where estradiol tends to promote heat dissipation, and progesterone tends to promote heat conservation and higher body temperatures. Changes in thermoregulation over the course of the menstrual cycle and with hot flashes at menopause are mediated by hormonal influences on neural control of skin blood flow and sweating...
May 9, 2017: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/28472898/the-relation-among-steroid-hormone-levels-lipid-profile-and-menopausal-symptom-severity
#13
Cihan Kaya, Hüseyin Cengiz, Ali Yeşil, Murat Ekin, Levent Yaşar
INTRODUCTION: Many postmenopausal women experience hot flashes, night sweats, non-specific emotional and psychological distresses. Our aim was to investigate the relation among steroid hormone levels, lipid profile and menopausal symptom severity using the menopause rating scale (MRS). METHODS: A cross-sectional study was performed at our outpatient clinic with natural postmenopausal women. A total of 444 women were included in this study. The basic characteristics of the study population, such as age, gravidity, parity, time to menopause onset and body mass index (BMI) were recorded...
May 4, 2017: Journal of Psychosomatic Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28399006/quantitative-analysis-of-placebo-response-and-factors-associated-with-menopausal-hot-flashes
#14
Lujin Li, Ling Xu, Junyi Wu, Lidan Dong, Yinghua Lv, Qingshan Zheng
OBJECTIVE: The aim of the study was to quantitatively analyze the placebo response and the factors associated with menopausal hot flashes. METHODS: The PubMed and Cochrane Library databases were searched for placebo-controlled trials that reported the treatment of menopausal hot flashes, with a retrieval deadline of December 31, 2015. The clinical and demographic characteristics of participants and placebo responses, defined as the percentage of reduction in hot flashes at each observation time point compared with that of baseline values, were extracted from the studies...
April 10, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28380486/neurokinin-3-receptor-antagonism-reveals-roles-for-neurokinin-b-in-the-regulation-of-gonadotropin-secretion-and-hot-flashes-in-postmenopausal-women
#15
Karolina Skorupskaite, Jyothis T George, Johannes D Veldhuis, Robert P Millar, Richard A Anderson
OBJECTIVES: Neurokinin B (NKB) and kisspeptin are obligate for normal gonadotropin secretion, and links between GnRH pulsatility and vasomotor symptoms have been proposed. Using a selective NKB receptor (NK3R) antagonist, the role of NKB in the hypergonadotropic state in menopausal women was explored. METHODS: Eleven postmenopausal women were administered the NK3R antagonist MLE4901, 40 mg twice daily orally for 7 days. 10-min blood sampling for 8 h was performed before and on the last day of NK3R antagonist treatment for LH pulsatility analysis with kisspeptin-10 (0...
April 5, 2017: Neuroendocrinology
https://www.readbyqxmd.com/read/28364498/sleep-characteristics-and-carotid-atherosclerosis-among-midlife-women
#16
Rebecca C Thurston, Yuefang Chang, Roland von Känel, Emma Barinas-Mitchell, J Richard Jennings, Martica H Hall, Nanette Santoro, Daniel J Buysse, Karen A Matthews
Introduction: Midlife, which encompasses the menopause transition in women, can be a time of disrupted sleep and accelerated atherosclerosis accumulation. Short or poor sleep quality has been associated with cardiovascular disease (CVD) risk; few studies have investigated relations among midlife women. We tested whether shorter actigraphy sleep time or poorer subjective sleep quality was associated with carotid atherosclerosis among midlife women. Aims and Methods: Two hundred fifty-six peri- and postmenopausal women aged 40-60 years completed 3 days of wrist actigraphy, hot flash monitoring, questionnaires (Pittsburgh Sleep Quality Index [PSQI], Berlin), a blood draw, and carotid ultrasound [intima media thickness (IMT), plaque]...
February 1, 2017: Sleep
https://www.readbyqxmd.com/read/28350757/acupuncture-for-menopausal-hot-flashes-clinical-evidence-update-and-its-relevance-to-decision-making
#17
Carolyn Ee, Simon D French, Charlie C Xue, Marie Pirotta, Helena Teede
OBJECTIVE: There is conflicting evidence on the efficacy and effectiveness of acupuncture for menopausal hot flashes. This article synthesizes the best available evidence for when women are considering whether acupuncture might be useful for menopausal hot flashes. METHODS: We searched electronic databases to identify randomized controlled trials and systematic reviews of acupuncture for menopausal hot flushes. RESULTS: The overall evidence demonstrates that acupuncture is effective when compared with no treatment, but not efficacious compared with sham...
March 27, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28278010/the-effect-of-valerian-on-the-severity-and-frequency-of-hot-flashes-a-triple-blind-randomized-clinical-trial
#18
Ensiyeh Jenabi, Fatemeh Shobeiri, Seyyed Mohammad Mahdi Hazavehei, Ghodratollah Roshanaei
Valerian is one of the most widely used herbal supplements and a phytoestrogenic herb. The aim of this study was to determine the effect of Valerian on the severity and frequency of hot flashes. This triple-blind, randomized, controlled clinical trial was conducted during a three-month period in Hamadan, Iran, in 60 postmenopausal women aged 45-55 years. Participants were randomly assigned to one of two groups- either placebo or Valerian. An oral Valerian 530 mg capsule was given twice per day for two months...
February 16, 2017: Women & Health
https://www.readbyqxmd.com/read/28225431/menopause-and-big-data-word-adjacency-graph-modeling-of-menopause-related-chacha-data
#19
Janet S Carpenter, Doyle Groves, Chen X Chen, Julie L Otte, Wendy R Miller
OBJECTIVE: To detect and visualize salient queries about menopause using Big Data from ChaCha. METHODS: We used Word Adjacency Graph (WAG) modeling to detect clusters and visualize the range of menopause-related topics and their mutual proximity. The subset of relevant queries was fully modeled. We split each query into token words (ie, meaningful words and phrases) and removed stopwords (ie, not meaningful functional words). The remaining words were considered in sequence to build summary tables of words and two and three-word phrases...
July 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28219672/changes-in-cardiovascular-function-based-on-adrenalin-and-norepinephrine-metabolism-in-ovariectomized-rats
#20
Hai Jiang, Wenpei Bai, Wenjuan Wang, Jing Zhang, Ke Wang, Yao Liu, Shuya Liu, Jing Jia, Lihua Qin
Menopause is a cardiovascular risk factor in women, and cardiovascular changes during perimenopause can increase the risk. We observed the influence of plasma adrenalin and norepinephrine and their metabolites on the cardiovascular system and the rectification effect of estrogen in ovariectomized rats. Fifty-four adult female Sprague-Dawley rats were randomly divided into sham (Sham), ovariectomized (OVX), or ovariectomized+estrogen treatment groups (OVX+E), with 18 rats in each. The Sham and OVX groups were given normal saline and the OVX+E group was given estradiol valerate beginning 2weeks after ovariectomy and continuing for 4weeks...
May 2017: Experimental Gerontology
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